PL1608685T3 - Antagoniści VEGF do leczenia cukrzycy - Google Patents

Antagoniści VEGF do leczenia cukrzycy

Info

Publication number
PL1608685T3
PL1608685T3 PL04758372T PL04758372T PL1608685T3 PL 1608685 T3 PL1608685 T3 PL 1608685T3 PL 04758372 T PL04758372 T PL 04758372T PL 04758372 T PL04758372 T PL 04758372T PL 1608685 T3 PL1608685 T3 PL 1608685T3
Authority
PL
Poland
Prior art keywords
vegf
diabetes
treatment
vegf antagonists
blocking
Prior art date
Application number
PL04758372T
Other languages
English (en)
Inventor
Mark W Sleeman
Stanley J Wiegand
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of PL1608685T3 publication Critical patent/PL1608685T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL04758372T 2003-03-28 2004-03-26 Antagoniści VEGF do leczenia cukrzycy PL1608685T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45879003P 2003-03-28 2003-03-28
EP04758372A EP1608685B1 (en) 2003-03-28 2004-03-26 Vegf antagonists for the treatment of diabetes
PCT/US2004/009246 WO2004087206A2 (en) 2003-03-28 2004-03-26 Methods of treating diabetes by blocking vegf-mediated activity

Publications (1)

Publication Number Publication Date
PL1608685T3 true PL1608685T3 (pl) 2007-07-31

Family

ID=33131825

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04758372T PL1608685T3 (pl) 2003-03-28 2004-03-26 Antagoniści VEGF do leczenia cukrzycy

Country Status (16)

Country Link
US (1) US7052691B2 (pl)
EP (1) EP1608685B1 (pl)
JP (2) JP4730909B2 (pl)
AT (1) ATE354592T1 (pl)
AU (1) AU2004226417B2 (pl)
BR (1) BRPI0408749B1 (pl)
CA (1) CA2519787C (pl)
CY (1) CY1106530T1 (pl)
DE (1) DE602004004883T2 (pl)
DK (1) DK1608685T3 (pl)
ES (1) ES2278333T3 (pl)
MX (1) MXPA05008972A (pl)
PL (1) PL1608685T3 (pl)
PT (1) PT1608685E (pl)
SI (1) SI1608685T1 (pl)
WO (1) WO2004087206A2 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7378095B2 (en) 2004-07-30 2008-05-27 Regeneron Pharmaceuticals, Inc. Methods of treating type I diabetes by blocking VEGF-mediated activity
CN102614134B (zh) * 2005-03-25 2016-09-07 瑞泽恩制药公司 Vegf拮抗剂制剂
RU2432155C3 (ru) 2006-06-16 2017-11-17 Ридженерон Фармасьютикалз, Инк. Составы антагониста vegf, подходящие для интравитреального введения
ES2345596B1 (es) * 2009-03-26 2011-07-13 Fundacion Progreso Y Salud Composicion para la prevencion o el tratamiento de la diabetes mellitus.
US20100330098A1 (en) * 2009-06-29 2010-12-30 Kuo Calvin J Methods to regulate glucose metabolism
MX385629B (es) 2011-01-13 2025-03-18 Regeneron Pharma Uso de un antagonista de factor de crecimiento endotelial vascular para tratar trastornos oculares angiogenicos.
JO3283B1 (ar) 2011-04-26 2018-09-16 Sanofi Sa تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI)
PE20170142A1 (es) 2014-01-25 2017-04-02 Chengdu Kanghong Biotechnologies Co Ltd Proteina de fusion que inhibe angiogenesis o crecimiento y uso de la misma
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
ES2732925T3 (es) 2014-07-18 2019-11-26 Sanofi Sa Método para predecir el resultado de un tratamiento con aflibercept de un paciente que se sospecha que padece un cáncer
KR20250057128A (ko) 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
ITUB20169928A1 (it) * 2016-01-12 2017-07-12 Medical And Biotechnological Services In Sigla M B S Srl Formulazioni farmaceutiche per il trattamento del diabete
SMT202200374T1 (it) 2017-11-30 2022-11-18 Regeneron Pharma Uso di un antagonista del vegf per trattare disturbi angiogenici dell’occhio
MX2020009152A (es) 2018-03-02 2020-11-09 Kodiak Sciences Inc Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos.
CN114786731A (zh) 2019-10-10 2022-07-22 科达制药股份有限公司 治疗眼部病症的方法
JP2023525034A (ja) 2020-05-08 2023-06-14 リジェネロン・ファーマシューティカルズ・インコーポレイテッド Vegfトラップおよびミニトラップならびに眼障害およびがんの治療方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9410533D0 (en) * 1994-05-26 1994-07-13 Lynxvale Ltd In situ hybridisation and immuno-Chemical localisation of a growth factor
WO2000064946A2 (en) * 1999-04-28 2000-11-02 Board Of Regents, The University Of Texas System Compositions and methods for cancer treatment by selectively inhibiting vegf
CA2376379C (en) 1999-06-08 2007-08-07 Regeneron Pharmaceuticals, Inc. Modified chimeric polypeptides with improved pharmacokinetic properties
US6833349B2 (en) 1999-06-08 2004-12-21 Regeneron Pharmaceuticals, Inc. Methods of treating inflammatory skin diseases

Also Published As

Publication number Publication date
SI1608685T1 (sl) 2007-08-31
PT1608685E (pt) 2007-05-31
WO2004087206A2 (en) 2004-10-14
ES2278333T3 (es) 2007-08-01
BRPI0408749B1 (pt) 2016-10-04
JP4730909B2 (ja) 2011-07-20
EP1608685A2 (en) 2005-12-28
WO2004087206A3 (en) 2004-12-16
DK1608685T3 (da) 2007-06-11
HK1080092A1 (en) 2006-04-21
CA2519787C (en) 2012-06-05
MXPA05008972A (es) 2005-11-04
CA2519787A1 (en) 2004-10-14
AU2004226417B2 (en) 2009-01-22
BRPI0408749A (pt) 2006-03-28
JP2006521397A (ja) 2006-09-21
US7052691B2 (en) 2006-05-30
US20040213787A1 (en) 2004-10-28
DE602004004883D1 (de) 2007-04-05
CY1106530T1 (el) 2012-01-25
DE602004004883T2 (de) 2007-11-15
ATE354592T1 (de) 2007-03-15
AU2004226417A1 (en) 2004-10-14
EP1608685B1 (en) 2007-02-21
JP2011037894A (ja) 2011-02-24

Similar Documents

Publication Publication Date Title
SI1608685T1 (sl) Antagonisti VEGF za zdravljenje diabetesa
ATE321048T1 (de) Beta-amino-tetrahydroimidazo(1,2-a)pyrazine und - tetrahydrotriazolo(4,3-a)pyrazine als dipeptidyl peptidase inhibitoren zur behandlung oder prevention von diabetes
AP1913A (en) Substituted benzazoles and use thereof as raf kinase inhibitors
MXPA05010819A (es) Uso de antagonistas de opioide perifericos, especialmente metilnaltrexona para tratar sindrome de intestino irritable.
ATE435015T1 (de) Substituierte benzazole und ihre verwendung als raf-kinase-hemmer
MY169308A (en) Treatment of tnf? related disorders
WO2004105757A3 (en) Use of rho-kinase inhibitors in the treatment of aneurysm and cardiac hypertrophy
DE60133029D1 (de) Mittel zur prävention oder behandlung von psoriasi
TW200716673A (en) Use of TNF &ahr; inhibitor for treatment of erosive polyarthritis
WO2004084943A8 (en) Use of antagonists of ghrelin or ghrelin receptor to treat intestinal inflammation
EA200801118A1 (ru) Способ ингибирования flt3 киназы
MXPA05001649A (es) Uso de compuestos antagonistas del cgrp para tratamiento de la psoriasis.
EP1804811A4 (en) METHOD AND COMPOSITION FOR THE TREATMENT OF FLAVIVERS, PESTIVERS AND HEPACIVIRES
WO2007073497A3 (en) Calcium channel antagonists
MX2007001241A (es) Metodos para tratar diabetes tipo i mediante el bloqueo de la actividad mediada de vegf.
ATE520709T1 (de) Campylobacter-polypeptide und verwendungsverfahren
EA200800755A1 (ru) Ikk ингибиторы, предназначенные для лечения эндометриоза
WO2003037310A3 (en) Use of inhibitors of the abc drug transporter to increase the activity of anti-microbial agents
WO2007075852A3 (en) Calcium channel antagonists
WO2006060787A3 (en) Delaying or preventing onset of multiple sclerosis
DE60214019D1 (de) Stickstoff enthaltende heterozyklen und ihre verwendung als raf inhibitoren
EA200800766A1 (ru) Ингибиторы pi3k для лечения эндометриоза
DE602004022423D1 (de) Hemmung der s6-kinase-aktivität zur behandlung von insulinresistenz
WO2004047762A3 (en) Methods for treating cancer using porimin as a target
NO20004363L (no) Anvendelse av D1-/D5-antagonister for behandling av tvangsforstyrrelser, somatoforme forstyrrelser, dissosiative forstyrrelser, impulskontrollforstyrrelser og autisme