PL139646B1 - Process for preparing novel 5-/substituted phenyl/-hydantoins - Google Patents

Process for preparing novel 5-/substituted phenyl/-hydantoins Download PDF

Info

Publication number
PL139646B1
PL139646B1 PL1983244350A PL24435083A PL139646B1 PL 139646 B1 PL139646 B1 PL 139646B1 PL 1983244350 A PL1983244350 A PL 1983244350A PL 24435083 A PL24435083 A PL 24435083A PL 139646 B1 PL139646 B1 PL 139646B1
Authority
PL
Poland
Prior art keywords
formula
compounds
sodium
solution
ether
Prior art date
Application number
PL1983244350A
Other languages
English (en)
Polish (pl)
Other versions
PL244350A1 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PL244350A1 publication Critical patent/PL244350A1/xx
Publication of PL139646B1 publication Critical patent/PL139646B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL1983244350A 1982-11-01 1983-10-28 Process for preparing novel 5-/substituted phenyl/-hydantoins PL139646B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/438,199 US4452806A (en) 1982-11-01 1982-11-01 Treating diabetic complications with 5-(substituted phenyl)hydantoins

Publications (2)

Publication Number Publication Date
PL244350A1 PL244350A1 (en) 1985-02-13
PL139646B1 true PL139646B1 (en) 1987-02-28

Family

ID=23739660

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1983244350A PL139646B1 (en) 1982-11-01 1983-10-28 Process for preparing novel 5-/substituted phenyl/-hydantoins

Country Status (13)

Country Link
US (1) US4452806A (esLanguage)
JP (1) JPS5998063A (esLanguage)
KR (1) KR860001507B1 (esLanguage)
CA (1) CA1203241A (esLanguage)
DK (1) DK158724C (esLanguage)
ES (1) ES526841A0 (esLanguage)
FI (1) FI80265C (esLanguage)
GR (1) GR79638B (esLanguage)
HU (1) HU191887B (esLanguage)
PL (1) PL139646B1 (esLanguage)
PT (1) PT77578A (esLanguage)
YU (1) YU43556B (esLanguage)
ZA (1) ZA838092B (esLanguage)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030060898A (ko) 2000-09-25 2003-07-16 이비덴 가부시키가이샤 반도체소자,반도체소자의 제조방법,다층프린트배선판 및다층프린트배선판의 제조방법
IT1319201B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per il diabete.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189587A (en) * 1977-04-05 1980-02-19 Ciba-Geigy Corporation 1,3-Diaminomethyl-hydantoin additives for lubricating oils
FR2458546A1 (fr) * 1979-06-07 1981-01-02 Hoechst France Procede de fabrication d'aryl-5 hydantoines racemiques et produits nouveaux en resultant

Also Published As

Publication number Publication date
DK499983A (da) 1984-05-02
ZA838092B (en) 1985-06-26
YU216783A (en) 1986-02-28
HU191887B (en) 1987-04-28
CA1203241A (en) 1986-04-15
US4452806A (en) 1984-06-05
YU43556B (en) 1989-08-31
DK499983D0 (da) 1983-11-01
PT77578A (en) 1983-11-01
FI80265C (fi) 1990-05-10
PL244350A1 (en) 1985-02-13
KR860001507B1 (ko) 1986-09-30
FI833993A0 (fi) 1983-10-31
JPH0465832B2 (esLanguage) 1992-10-21
KR840006630A (ko) 1984-12-01
DK158724B (da) 1990-07-09
ES8507119A1 (es) 1985-05-01
DK158724C (da) 1990-11-19
FI833993A7 (fi) 1984-05-02
FI80265B (fi) 1990-01-31
ES526841A0 (es) 1985-05-01
GR79638B (esLanguage) 1984-10-31
JPS5998063A (ja) 1984-06-06

Similar Documents

Publication Publication Date Title
FI62838B (fi) Foerfarande foer framstaellning av den nya farmaceutiskt anvaendbara hoegerroterande isomeren av en asymmetriskt spiro-hydantoinfoerening
US4198421A (en) Antiinflammatory 2-substituted-dibenzo[2,3:6,7]oxepino[4,5-d]imidazoles
GB2140412A (en) Thiazolidine derivatives, process for the preparation and pharmaceutical compositions thereof
CN112430221B (zh) 用于预防、治疗或减轻高尿酸血症或痛风的化合物及其应用
JPS6052157B2 (ja) スピロ−多環式イミダゾリジンジオン誘導体
PT92180B (pt) Processo para a preparacao de novas mevalonolactonas do tipo tienopiridina e de composicoes farmaceuticas que as contem
US4259344A (en) Sulfur-containing benzimidazole derivatives
CA1269389A (en) PROCESS FOR PREPARING .gamma.-BUTYROLACTONE DERIVATIVES, AND IMMUNOMODULATING COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS
PL139646B1 (en) Process for preparing novel 5-/substituted phenyl/-hydantoins
AU644454B2 (en) Novel oxazole derivatives, a preparation method therefor and pharmaceutical compositions containing same
FI87460C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 7-fenyl-, naftyl- och bensofuranylisotiazolo/4,5-d/-1,2,3-triazin-4(3h)-oner
EP0335979A1 (en) Thienopyrimidine derivatives
PL147400B1 (en) Method of obtaining novel derivatives of spiro imidazolidine
US5326883A (en) Oxime ether derivatives having lipoxygenase inhibitory activity
US4176190A (en) Diuretic and saliuretic sulphamoylbenzoic acids
GB2192002A (en) Glycine derivatives
NZ198192A (en) 1-substituted-1h-tetrazol-5-amines and pharmaceutical compositions
US4882340A (en) Benzofuran derivative and processes for preparing the same
US6194585B1 (en) Process for preparing 5-lipoxygenase inhibitors
AU610629B2 (en) Improvements in or relating to leukotriene antagonists
EP0294994B1 (en) 3-4-Dihydro-2-alkyl-3-oxo-N-aryl-2H-[1]benzothieno[3,2-el]-1,2-thiazine-4-carboxamide-1,1-dioxides
JPH08505877A (ja) 抗増殖剤としての縮合複素環式グルタミン酸誘導体
EP0666253A1 (en) N-t-BUTYLANILINE ANALOG AND LIPID LEVEL DEPRESSANT CONTAINING THE SAME
CA1195689A (en) Aldose reductase inhibiting 5-(2-alkoxy-3-substituted phenyl) hydantoins
US20250129055A1 (en) Glucoside derivative, and preparation method therefor and application thereof