PH31115A - Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained. - Google Patents
Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained.Info
- Publication number
- PH31115A PH31115A PH45320A PH45320A PH31115A PH 31115 A PH31115 A PH 31115A PH 45320 A PH45320 A PH 45320A PH 45320 A PH45320 A PH 45320A PH 31115 A PH31115 A PH 31115A
- Authority
- PH
- Philippines
- Prior art keywords
- obtaining
- pure preparations
- products obtained
- melarsomine dihydrochloride
- intermediate products
- Prior art date
Links
- WMZUMAJTJUZEKQ-UHFFFAOYSA-N 2-n-[4-[bis(2-aminoethylsulfanyl)arsanyl]phenyl]-1,3,5-triazine-2,4,6-triamine;dihydrochloride Chemical compound Cl.Cl.C1=CC([As](SCCN)SCCN)=CC=C1NC1=NC(N)=NC(N)=N1 WMZUMAJTJUZEKQ-UHFFFAOYSA-N 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 229960004330 melarsomine dihydrochloride Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/80—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/74—Aromatic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR919114904A FR2684382B1 (fr) | 1991-12-02 | 1991-12-02 | Medicaments et preparations pures de dichlorhydrate de melarsomine, leur procede d'obtention et produits intermediaires obtenus. |
Publications (1)
Publication Number | Publication Date |
---|---|
PH31115A true PH31115A (en) | 1998-02-23 |
Family
ID=9419573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH45320A PH31115A (en) | 1991-12-02 | 1992-11-25 | Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained. |
Country Status (15)
Country | Link |
---|---|
US (3) | US5459263A (pt) |
JP (1) | JP3578277B2 (pt) |
AU (1) | AU667329B2 (pt) |
BR (1) | BR9204643A (pt) |
CA (1) | CA2083766C (pt) |
ES (1) | ES2039311B1 (pt) |
FR (1) | FR2684382B1 (pt) |
GR (1) | GR920100526A (pt) |
IT (1) | IT1256117B (pt) |
MA (1) | MA22723A1 (pt) |
MX (1) | MX9206890A (pt) |
MY (1) | MY111175A (pt) |
PH (1) | PH31115A (pt) |
PT (1) | PT101105B (pt) |
TW (1) | TW358099B (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2684382B1 (fr) * | 1991-12-02 | 1994-10-21 | Rhone Merieux | Medicaments et preparations pures de dichlorhydrate de melarsomine, leur procede d'obtention et produits intermediaires obtenus. |
US6191123B1 (en) * | 1999-03-19 | 2001-02-20 | Parker Hughes Institute | Organic-arsenic compounds |
AUPQ296799A0 (en) * | 1999-09-20 | 1999-10-14 | Unisearch Limited | A cell-membrane impermeable trivalent organoarsenical derivative and use thereof |
US20060166208A1 (en) | 2002-11-07 | 2006-07-27 | Hogg Philip J | Induction of the mitochondrial permeability transition |
US6686344B1 (en) | 2003-01-30 | 2004-02-03 | Paker Hughes Institute | Organic-arsonic compounds |
AU2007314076B2 (en) | 2006-11-01 | 2012-07-19 | Newsouth Innovations Pty Limited | Organo-arsenoxide compounds and use thereof |
US8373412B2 (en) * | 2009-01-23 | 2013-02-12 | Baker Hughes Incorporated | NMR-LWD imaging tool |
US8324895B2 (en) * | 2009-01-23 | 2012-12-04 | Baker Hughes Incorporated | MWD/LWD NMR imaging with long echo trains |
CN102558234B (zh) * | 2011-04-08 | 2015-01-07 | 浙江工商大学 | 一种通过对氨基苯胂酸重氮化制备阿散酸制剂的方法 |
CN102558235B (zh) * | 2011-04-08 | 2015-01-07 | 浙江工商大学 | 一种通过三甲氧苄氨嘧啶重氮化制备阿散酸制剂的方法 |
US20140051840A1 (en) * | 2012-08-17 | 2014-02-20 | The Curators Of The University Of Missouri | Arsenic complexes for potential diagnostic applications |
US9593052B2 (en) | 2012-08-17 | 2017-03-14 | The Curators Of The University Of Missouri | Arsenic complexes for potential diagnostic applications |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL54891C (pt) * | 1938-12-23 | 1900-01-01 | ||
CH242529A (de) * | 1940-12-10 | 1946-05-15 | Friedheim Ernst Albert Hermann | Verfahren zur Darstellung von m-(2,4-Diamino-1,3,5-triazinyl-(6))-amino-phenylarsinoxyd. |
NL60802C (pt) * | 1940-12-10 | |||
US2422724A (en) * | 1944-01-20 | 1947-06-24 | Ernst A H Friedheim | Substituted 1,3,5-triazinyl-(6)-aminophenyl-arsenic compounds |
US2400547A (en) * | 1944-01-20 | 1946-05-21 | Ernst A H Friedheim | Substituted 1, 3, 5-triazinyl-(6)-aminophenyl-arsenic compounds |
US2390091A (en) * | 1944-06-03 | 1945-11-27 | Ernst A H Friedheim | Substituted 1,3,5-triazinyl-(6)-aminophenyl-arsenic compounds |
CH245837A (de) * | 1946-11-16 | 1946-11-30 | Dr Friedheim Ernst A H | Verfahren zur Darstellung von p-2,4-Diamino-1,3,5-triazinyl-(6)-amino-phenyl-arsenoxyd. |
CH254164A (de) * | 1946-11-16 | 1948-04-15 | Dr Friedheim Ernst A H | Verfahren zur Darstellung von p-(2,4-Diamino-1,3,5-triazinyl-(6)-aminophenyl-arsenoxyd. |
US2659723A (en) * | 1947-01-28 | 1953-11-17 | Ernst A H Friedheim | Triazine organometallic compounds and process for preparing same |
US2593434A (en) * | 1947-02-19 | 1952-04-22 | Ernst A H Friedheim | Propylene glycol solution of arsenic medicaments |
US3482171A (en) * | 1966-07-15 | 1969-12-02 | Itt | Bidirectional electronic phase shifter |
US3856971A (en) * | 1971-07-20 | 1974-12-24 | E Friedheim | Method of combating filariasis in dogs |
BE786573A (fr) * | 1971-07-20 | 1973-01-22 | Hoechst Ag | Medicament a base de composes arsenicaux organiques et de derives du benzimidazole |
GB2024008B (en) * | 1978-06-28 | 1983-02-16 | Merck & Co Inc | Compositions for treating trypanosomiasis infections |
ZW8781A1 (en) * | 1980-05-23 | 1981-12-16 | Hoffmann La Roche | 2-nitroimidazoles and preparation thereof |
US4514390A (en) * | 1982-04-12 | 1985-04-30 | The Rockefeller University | Melaminylthioarsenites |
FR2572730B1 (fr) * | 1984-11-02 | 1987-12-11 | Centre Nat Rech Scient | Nouveaux derives de l'arsenic, leur preparation et leur application, notamment comme medicaments antiparasitaires |
FR2640269B1 (fr) * | 1988-12-13 | 1991-03-15 | Maes Ludo | Composes organometalliques, leurs modes de preparation et compositions pharmaceutiques les contenant |
FR2684382B1 (fr) * | 1991-12-02 | 1994-10-21 | Rhone Merieux | Medicaments et preparations pures de dichlorhydrate de melarsomine, leur procede d'obtention et produits intermediaires obtenus. |
-
1991
- 1991-12-02 FR FR919114904A patent/FR2684382B1/fr not_active Expired - Lifetime
-
1992
- 1992-11-25 PH PH45320A patent/PH31115A/en unknown
- 1992-11-25 ES ES09202376A patent/ES2039311B1/es not_active Expired - Fee Related
- 1992-11-25 CA CA002083766A patent/CA2083766C/en not_active Expired - Lifetime
- 1992-11-25 IT ITMI922692A patent/IT1256117B/it active IP Right Grant
- 1992-11-26 GR GR920100526A patent/GR920100526A/el unknown
- 1992-11-27 MY MYPI92002180A patent/MY111175A/en unknown
- 1992-11-27 AU AU29720/92A patent/AU667329B2/en not_active Expired
- 1992-11-30 PT PT101105A patent/PT101105B/pt not_active IP Right Cessation
- 1992-11-30 MX MX9206890A patent/MX9206890A/es unknown
- 1992-12-01 MA MA23013A patent/MA22723A1/fr unknown
- 1992-12-01 BR BR9204643A patent/BR9204643A/pt not_active Application Discontinuation
- 1992-12-02 US US07/984,934 patent/US5459263A/en not_active Expired - Lifetime
- 1992-12-02 JP JP34986692A patent/JP3578277B2/ja not_active Expired - Lifetime
- 1992-12-11 TW TW081109949A patent/TW358099B/zh not_active IP Right Cessation
-
1995
- 1995-06-02 US US08/459,797 patent/US5635499A/en not_active Expired - Lifetime
-
1996
- 1996-09-05 US US08/707,613 patent/US5770733A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
TW358099B (en) | 1999-05-11 |
FR2684382B1 (fr) | 1994-10-21 |
PT101105B (pt) | 1999-10-29 |
IT1256117B (it) | 1995-11-28 |
BR9204643A (pt) | 1993-06-08 |
AU667329B2 (en) | 1996-03-21 |
CA2083766C (en) | 2002-09-10 |
MY111175A (en) | 1999-09-30 |
US5635499A (en) | 1997-06-03 |
ITMI922692A0 (it) | 1992-11-25 |
MX9206890A (es) | 1993-08-01 |
US5459263A (en) | 1995-10-17 |
FR2684382A1 (fr) | 1993-06-04 |
CA2083766A1 (en) | 1993-06-03 |
MA22723A1 (fr) | 1993-07-01 |
PT101105A (pt) | 1994-03-31 |
US5770733A (en) | 1998-06-23 |
ES2039311A1 (es) | 1993-09-16 |
ITMI922692A1 (it) | 1994-05-25 |
JPH0624960A (ja) | 1994-02-01 |
ES2039311B1 (es) | 1997-08-16 |
AU2972092A (en) | 1993-06-03 |
GR920100526A (el) | 1993-08-31 |
JP3578277B2 (ja) | 2004-10-20 |
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