PH26277A - Plaster used as therapeutic system for the administration of active substances to the skin which exhibits a graduated active substance and process for the production thereof - Google Patents
Plaster used as therapeutic system for the administration of active substances to the skin which exhibits a graduated active substance and process for the production thereof Download PDFInfo
- Publication number
- PH26277A PH26277A PH40156A PH40156A PH26277A PH 26277 A PH26277 A PH 26277A PH 40156 A PH40156 A PH 40156A PH 40156 A PH40156 A PH 40156A PH 26277 A PH26277 A PH 26277A
- Authority
- PH
- Philippines
- Prior art keywords
- active substance
- matrix
- plaster
- deposit
- plaster according
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title claims description 115
- 239000011505 plaster Substances 0.000 title claims description 89
- 238000004519 manufacturing process Methods 0.000 title claims description 21
- 238000000034 method Methods 0.000 title claims description 20
- 230000001225 therapeutic effect Effects 0.000 title claims description 12
- 239000011159 matrix material Substances 0.000 claims abstract description 97
- 239000010410 layer Substances 0.000 claims abstract description 56
- 238000009792 diffusion process Methods 0.000 claims abstract description 14
- 239000003814 drug Substances 0.000 claims abstract description 12
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims description 25
- 230000003578 releasing effect Effects 0.000 claims description 12
- 238000012423 maintenance Methods 0.000 claims description 9
- 239000000126 substance Substances 0.000 claims description 8
- 239000011241 protective layer Substances 0.000 claims description 7
- 239000000853 adhesive Substances 0.000 claims description 6
- 230000001070 adhesive effect Effects 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- 230000009969 flowable effect Effects 0.000 claims description 4
- 239000012752 auxiliary agent Substances 0.000 claims description 3
- 239000006185 dispersion Substances 0.000 claims description 3
- 230000002500 effect on skin Effects 0.000 claims description 3
- 239000000155 melt Substances 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 230000009885 systemic effect Effects 0.000 claims description 3
- 230000000063 preceeding effect Effects 0.000 claims 4
- 238000011065 in-situ storage Methods 0.000 claims 2
- 241000206607 Porphyra umbilicalis Species 0.000 claims 1
- 238000012856 packing Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 abstract description 9
- 239000012790 adhesive layer Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 230000004907 flux Effects 0.000 description 6
- 230000035515 penetration Effects 0.000 description 6
- -1 e.g. Substances 0.000 description 5
- 238000001727 in vivo Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 239000000306 component Substances 0.000 description 4
- 238000010276 construction Methods 0.000 description 4
- 230000000875 corresponding effect Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 229920001577 copolymer Polymers 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000011888 foil Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- GLVVKKSPKXTQRB-UHFFFAOYSA-N ethenyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OC=C GLVVKKSPKXTQRB-UHFFFAOYSA-N 0.000 description 2
- 230000001747 exhibiting effect Effects 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 2
- 239000011976 maleic acid Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229960002715 nicotine Drugs 0.000 description 2
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920000193 polymethacrylate Polymers 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 239000005060 rubber Substances 0.000 description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 229920000298 Cellophane Polymers 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- 229920002292 Nylon 6 Polymers 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical class CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 230000000390 anti-adipogenic effect Effects 0.000 description 1
- 230000003474 anti-emetic effect Effects 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 229940125683 antiemetic agent Drugs 0.000 description 1
- 239000002111 antiemetic agent Substances 0.000 description 1
- 239000002830 appetite depressant Substances 0.000 description 1
- 230000036765 blood level Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000036576 dermal application Effects 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 229960004667 ethyl cellulose Drugs 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920001289 polyvinyl ether Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000002557 soporific effect Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Medical Informatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3908432A DE3908432A1 (de) | 1989-03-14 | 1989-03-14 | Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
PH26277A true PH26277A (en) | 1992-04-10 |
Family
ID=6376397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH40156A PH26277A (en) | 1989-03-14 | 1990-03-07 | Plaster used as therapeutic system for the administration of active substances to the skin which exhibits a graduated active substance and process for the production thereof |
Country Status (28)
Country | Link |
---|---|
US (1) | US5176915A (no) |
EP (1) | EP0387694B1 (no) |
JP (1) | JP2588039B2 (no) |
KR (1) | KR950013462B1 (no) |
AT (1) | ATE133569T1 (no) |
AU (1) | AU622775B2 (no) |
CA (1) | CA2012124A1 (no) |
CZ (1) | CZ286264B6 (no) |
DD (1) | DD296844A5 (no) |
DE (2) | DE3908432A1 (no) |
DK (1) | DK0387694T3 (no) |
ES (1) | ES2085293T3 (no) |
FI (1) | FI107371B (no) |
GR (1) | GR3019786T3 (no) |
HR (1) | HRP930666B1 (no) |
HU (1) | HU206992B (no) |
IE (1) | IE74681B1 (no) |
IL (1) | IL93679A (no) |
MY (1) | MY107088A (no) |
NO (1) | NO901127L (no) |
NZ (1) | NZ232896A (no) |
PH (1) | PH26277A (no) |
PL (1) | PL162638B1 (no) |
PT (1) | PT93431B (no) |
SI (1) | SI9010494B (no) |
SK (1) | SK280996B6 (no) |
YU (1) | YU48229B (no) |
ZA (1) | ZA901940B (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4110027C2 (de) * | 1991-03-27 | 1996-08-29 | Lohmann Therapie Syst Lts | Verfahren zur Konfektionierung transdermaler therapeutischer Pflaster |
JP3212340B2 (ja) * | 1992-01-27 | 2001-09-25 | アルケア株式会社 | 皮膚保護用ペースト状組成物 |
DK170792B1 (da) * | 1992-08-27 | 1996-01-22 | Coloplast As | Hudpladeprodukt til dosering af et eller flere medikamenter |
US5523095A (en) * | 1993-12-15 | 1996-06-04 | Eastman Chemical Company | Controlled release matrix system using cellulose acetate/polyvinylpyrrolidone blends |
US5536505A (en) * | 1993-12-15 | 1996-07-16 | Eastman Chemical Company | Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends |
US5547681A (en) * | 1994-07-14 | 1996-08-20 | Union Carbide Chemicals & Plastics Technology Corporation | Dermal patch |
DE19802050A1 (de) * | 1998-01-21 | 1999-07-22 | Labtec Gmbh | Zubereitung zur Freisetzung von Coenzym Q 10 in die Mundhöhle |
US5939477A (en) * | 1998-02-02 | 1999-08-17 | Dow Corning Corporation | Silicone pressure sensitive adhesive composition containing functionalized polyisobutylene |
FR2784581B1 (fr) * | 1998-10-20 | 2002-12-13 | Oreal | Patch, ensemble constitue d'un patch et d'un recipient, et procede |
NZ512788A (en) * | 1998-12-07 | 2003-07-25 | Elan Corp Plc | Transdermal patch for delivering volatile liquid drugs |
US6974588B1 (en) | 1999-12-07 | 2005-12-13 | Elan Pharma International Limited | Transdermal patch for delivering volatile liquid drugs |
WO2001052823A2 (en) | 2000-01-20 | 2001-07-26 | Noven Pharmaceuticals, Inc. | Compositions to effect the release profile in the transdermal administration of drugs |
FR2804870B1 (fr) | 2000-02-16 | 2002-08-16 | Oreal | Structure composite a matrice adhesive contenant un ou plusieurs actifs |
DE10110391A1 (de) * | 2001-03-03 | 2002-09-26 | Lohmann Therapie Syst Lts | Hochflexibles Nikotin transdermales therapeutisches System mit Nikotin als Wirkstoff |
FR2822711B1 (fr) * | 2001-03-28 | 2003-06-13 | Oreal | Dispositif de traitement comportant une enveloppe definissant une cavite dans laquelle peut-etre engagee une partie du corps |
AR033748A1 (es) * | 2002-05-15 | 2004-01-07 | Thalas Group Inc | Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo |
US20050202073A1 (en) | 2004-03-09 | 2005-09-15 | Mylan Technologies, Inc. | Transdermal systems containing multilayer adhesive matrices to modify drug delivery |
US9205062B2 (en) * | 2004-03-09 | 2015-12-08 | Mylan Pharmaceuticals, Inc. | Transdermal systems containing multilayer adhesive matrices to modify drug delivery |
US7888422B2 (en) * | 2005-11-09 | 2011-02-15 | Mylan Technologies Inc. | Long-wearing removable pressure sensitive adhesive |
DE102007006244B4 (de) * | 2007-02-08 | 2012-03-15 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System zur Verabreichung wasserlöslicher Wirkstoffe |
US9017301B2 (en) * | 2007-09-04 | 2015-04-28 | Mylan Technologies, Inc. | Transdermal drug delivery systems comprising a coated release liner |
AU2012240329A1 (en) | 2011-04-04 | 2013-10-10 | The Procter & Gamble Company | Personal care article |
WO2013025761A1 (en) | 2011-08-15 | 2013-02-21 | The Procter & Gamble Company | Conformable personal care articles |
US8795695B2 (en) | 2011-08-15 | 2014-08-05 | The Procter & Gamble Company | Personal care methods |
US9907738B2 (en) | 2013-06-27 | 2018-03-06 | The Procter & Gamble Company | Personal care compositions and articles |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3731683A (en) * | 1971-06-04 | 1973-05-08 | Alza Corp | Bandage for the controlled metering of topical drugs to the skin |
US4262003A (en) * | 1975-12-08 | 1981-04-14 | Alza Corporation | Method and therapeutic system for administering scopolamine transdermally |
JPS57179437U (no) * | 1981-05-06 | 1982-11-13 | ||
JPS5984819U (ja) * | 1982-11-29 | 1984-06-08 | 松下電器産業株式会社 | 油入静止機器巻線 |
US4597961A (en) * | 1985-01-23 | 1986-07-01 | Etscorn Frank T | Transcutaneous application of nicotine |
JPS6216414A (ja) * | 1985-07-11 | 1987-01-24 | Nitto Electric Ind Co Ltd | 複合製剤 |
US4698062A (en) * | 1985-10-30 | 1987-10-06 | Alza Corporation | Medical device for pulsatile transdermal delivery of biologically active agents |
US4666441A (en) * | 1985-12-17 | 1987-05-19 | Ciba-Geigy Corporation | Multicompartmentalized transdermal patches |
EP0249475A3 (en) * | 1986-06-13 | 1989-10-11 | Alza Corporation | Delayed percutaneous delivery |
DE3629304A1 (de) * | 1986-08-28 | 1988-03-24 | Lohmann Gmbh & Co Kg | Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung |
DE3809978A1 (de) * | 1988-03-24 | 1989-10-05 | Lohmann Gmbh & Co Kg | Reservoir fuer gesteuerte wirkstoffabgabe, dieses enthaltende vorrichtung, sowie verfahren zu deren herstellung und verwendung der vorrichtung |
-
1989
- 1989-03-14 DE DE3908432A patent/DE3908432A1/de active Granted
-
1990
- 1990-03-07 AU AU50766/90A patent/AU622775B2/en not_active Expired
- 1990-03-07 PH PH40156A patent/PH26277A/en unknown
- 1990-03-07 MY MYPI90000357A patent/MY107088A/en unknown
- 1990-03-08 CZ CS19901137A patent/CZ286264B6/cs not_active IP Right Cessation
- 1990-03-08 SK SK1137-90A patent/SK280996B6/sk not_active IP Right Cessation
- 1990-03-08 DK DK90104407.3T patent/DK0387694T3/da active
- 1990-03-08 ES ES90104407T patent/ES2085293T3/es not_active Expired - Lifetime
- 1990-03-08 AT AT90104407T patent/ATE133569T1/de not_active IP Right Cessation
- 1990-03-08 EP EP90104407A patent/EP0387694B1/de not_active Expired - Lifetime
- 1990-03-08 IL IL9367990A patent/IL93679A/en not_active IP Right Cessation
- 1990-03-08 DE DE59010095T patent/DE59010095D1/de not_active Expired - Lifetime
- 1990-03-09 NO NO90901127A patent/NO901127L/no unknown
- 1990-03-12 JP JP2058242A patent/JP2588039B2/ja not_active Expired - Lifetime
- 1990-03-13 NZ NZ232896A patent/NZ232896A/en unknown
- 1990-03-13 HU HU901423A patent/HU206992B/hu unknown
- 1990-03-13 DD DD90338651A patent/DD296844A5/de not_active IP Right Cessation
- 1990-03-14 PT PT93431A patent/PT93431B/pt not_active IP Right Cessation
- 1990-03-14 PL PL28430090A patent/PL162638B1/pl unknown
- 1990-03-14 YU YU49490A patent/YU48229B/sh unknown
- 1990-03-14 IE IE91490A patent/IE74681B1/en not_active IP Right Cessation
- 1990-03-14 CA CA002012124A patent/CA2012124A1/en not_active Abandoned
- 1990-03-14 KR KR90003381A patent/KR950013462B1/ko not_active IP Right Cessation
- 1990-03-14 SI SI9010494A patent/SI9010494B/sl unknown
- 1990-03-14 ZA ZA901940A patent/ZA901940B/xx unknown
- 1990-03-15 FI FI901291A patent/FI107371B/fi active IP Right Grant
-
1991
- 1991-06-20 US US07/721,903 patent/US5176915A/en not_active Expired - Lifetime
-
1993
- 1993-04-01 HR HRP-494/90A patent/HRP930666B1/xx not_active IP Right Cessation
-
1996
- 1996-04-29 GR GR960401166T patent/GR3019786T3/el unknown
Also Published As
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