PH26002A - Gradual release structure for chewing gum - Google Patents
Gradual release structure for chewing gum Download PDFInfo
- Publication number
- PH26002A PH26002A PH39968A PH39968A PH26002A PH 26002 A PH26002 A PH 26002A PH 39968 A PH39968 A PH 39968A PH 39968 A PH39968 A PH 39968A PH 26002 A PH26002 A PH 26002A
- Authority
- PH
- Philippines
- Prior art keywords
- active agent
- wall material
- chewing gum
- gradual release
- fibers
- Prior art date
Links
- 235000015218 chewing gum Nutrition 0.000 title claims abstract description 39
- 229940112822 chewing gum Drugs 0.000 title claims abstract description 35
- 239000013543 active substance Substances 0.000 claims abstract description 110
- 239000000463 material Substances 0.000 claims abstract description 63
- 238000000034 method Methods 0.000 claims abstract description 46
- 238000002074 melt spinning Methods 0.000 claims abstract description 13
- 239000000835 fiber Substances 0.000 claims description 130
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical group OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 63
- 108010011485 Aspartame Proteins 0.000 claims description 62
- 239000000605 aspartame Substances 0.000 claims description 62
- 235000010357 aspartame Nutrition 0.000 claims description 62
- 229960003438 aspartame Drugs 0.000 claims description 62
- 229920002689 polyvinyl acetate Polymers 0.000 claims description 54
- 239000011118 polyvinyl acetate Substances 0.000 claims description 49
- 239000000203 mixture Substances 0.000 claims description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical group [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- 238000005520 cutting process Methods 0.000 claims description 4
- 239000008123 high-intensity sweetener Substances 0.000 claims description 4
- 235000013615 non-nutritive sweetener Nutrition 0.000 claims description 4
- NUFKRGBSZPCGQB-FLBSXDLDSA-N (3s)-3-amino-4-oxo-4-[[(2r)-1-oxo-1-[(2,2,4,4-tetramethylthietan-3-yl)amino]propan-2-yl]amino]butanoic acid;pentahydrate Chemical group O.O.O.O.O.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C NUFKRGBSZPCGQB-FLBSXDLDSA-N 0.000 claims description 3
- 239000004377 Alitame Substances 0.000 claims description 3
- 235000019409 alitame Nutrition 0.000 claims description 3
- 108010009985 alitame Proteins 0.000 claims description 3
- 239000011159 matrix material Substances 0.000 description 31
- 239000002904 solvent Substances 0.000 description 30
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 19
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 12
- 239000004615 ingredient Substances 0.000 description 12
- 229920000642 polymer Polymers 0.000 description 12
- 238000011068 loading method Methods 0.000 description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 10
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- 238000007664 blowing Methods 0.000 description 7
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- 229920005989 resin Polymers 0.000 description 7
- 239000007787 solid Substances 0.000 description 7
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- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
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- 238000006731 degradation reaction Methods 0.000 description 6
- 229920001971 elastomer Polymers 0.000 description 6
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- 238000009472 formulation Methods 0.000 description 6
- 239000004014 plasticizer Substances 0.000 description 6
- 239000001103 potassium chloride Substances 0.000 description 6
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- 239000004698 Polyethylene Substances 0.000 description 5
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- 150000003839 salts Chemical class 0.000 description 5
- 239000011780 sodium chloride Substances 0.000 description 5
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- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 4
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- VHOQXEIFYTTXJU-UHFFFAOYSA-N Isobutylene-isoprene copolymer Chemical compound CC(C)=C.CC(=C)C=C VHOQXEIFYTTXJU-UHFFFAOYSA-N 0.000 description 1
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- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
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- 239000003963 antioxidant agent Substances 0.000 description 1
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- 235000013871 bee wax Nutrition 0.000 description 1
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- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
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- 230000015572 biosynthetic process Effects 0.000 description 1
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- 235000015165 citric acid Nutrition 0.000 description 1
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- 239000003433 contraceptive agent Substances 0.000 description 1
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- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 1
- 239000000347 magnesium hydroxide Substances 0.000 description 1
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/02—Apparatus specially adapted for manufacture or treatment of chewing gum
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/18—Chewing gum characterised by shape, structure or physical form, e.g. aerated products
- A23G4/20—Composite products, e.g. centre-filled, multi-layer, laminated
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Confectionery (AREA)
- Medicinal Preparation (AREA)
- Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
- Seasonings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/340,384 US4978537A (en) | 1989-04-19 | 1989-04-19 | Gradual release structures for chewing gum |
Publications (1)
Publication Number | Publication Date |
---|---|
PH26002A true PH26002A (en) | 1992-01-29 |
Family
ID=23333138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH39968A PH26002A (en) | 1989-04-19 | 1990-01-30 | Gradual release structure for chewing gum |
Country Status (14)
Country | Link |
---|---|
US (1) | US4978537A (de) |
EP (1) | EP0423255B1 (de) |
JP (1) | JPH0751049B2 (de) |
CN (1) | CN1054884A (de) |
AT (1) | ATE95983T1 (de) |
AU (1) | AU619152B2 (de) |
CA (1) | CA1335763C (de) |
DE (1) | DE69004047T2 (de) |
DK (1) | DK0423255T3 (de) |
ES (1) | ES2045906T3 (de) |
FI (1) | FI906250A0 (de) |
NZ (1) | NZ232236A (de) |
PH (1) | PH26002A (de) |
WO (1) | WO1990012511A1 (de) |
Families Citing this family (137)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5387431A (en) | 1991-10-25 | 1995-02-07 | Fuisz Technologies Ltd. | Saccharide-based matrix |
US5516537A (en) * | 1987-04-20 | 1996-05-14 | Fuisz Technologies Ltd. | Frozen comestibles |
US5422136A (en) * | 1987-04-20 | 1995-06-06 | Fuisz Technologies Ltd. | Starch-based food enhancing ingredient |
US5370881A (en) * | 1987-04-20 | 1994-12-06 | Fuisz Technologies Ltd. | Water-soluble delivery systems for hydrophobic liquids |
US5286513A (en) * | 1987-04-20 | 1994-02-15 | Fuisz Technologies Ltd. | Proteinaceous food product containing a melt spun oleaginous matrix |
US5236734A (en) * | 1987-04-20 | 1993-08-17 | Fuisz Technologies Ltd. | Method of preparing a proteinaceous food product containing a melt spun oleaginous matrix |
US5456932A (en) * | 1987-04-20 | 1995-10-10 | Fuisz Technologies Ltd. | Method of converting a feedstock to a shearform product and product thereof |
US5229148A (en) * | 1989-04-19 | 1993-07-20 | Wm. Wrigley Jr. Company | Method of combining active ingredients with polyvinyl acetates |
US5108762A (en) * | 1989-04-19 | 1992-04-28 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
US5169658A (en) * | 1989-04-19 | 1992-12-08 | Wm. Wrigley Jr. Company | Polyvinyl acetate encapsulation of crystalline sucralose for use in chewing gum |
US5165944A (en) * | 1989-04-19 | 1992-11-24 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
US5139794A (en) * | 1989-04-19 | 1992-08-18 | Wm. Wrigley Jr. Company | Use of encapsulated salts in chewing gum |
US5154939A (en) * | 1989-04-19 | 1992-10-13 | Wm. Wrigley Jr. Company | Use of salt to improve extrusion encapsulation of chewing gum ingredients |
US5198251A (en) * | 1989-04-19 | 1993-03-30 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
NZ235372A (en) * | 1989-10-10 | 1992-05-26 | Wrigley W M Jun Co | Slow release delivery system made by fibre melt spinning techniques producing a fibre about 1mm diameter, exterior is substantially wall material and core mostly active agent dispersed through the fibre material which is porous overall |
US5139798A (en) * | 1990-11-21 | 1992-08-18 | Wm. Wrigley Jr. Company | Polyvinyl acetate encapsulation of codried sucralose for use in chewing gum |
US5196199A (en) * | 1990-12-14 | 1993-03-23 | Fuisz Technologies Ltd. | Hydrophilic form of perfluoro compounds and method of manufacture |
US5128155A (en) * | 1990-12-20 | 1992-07-07 | Wm. Wrigley Jr. Company | Flavor releasing structures for chewing gum |
US5154938A (en) * | 1990-12-20 | 1992-10-13 | Wm. Wrigley Jr. Company | Gum composition having dispersed porous beads containing plasticizers |
US5116627A (en) * | 1991-03-07 | 1992-05-26 | International Flavors & Fragrances Inc. | Chewing gum containing compositions for controlled release of flavor bearing substances and process for producing same |
KR100241403B1 (ko) * | 1991-05-17 | 2000-02-01 | 리차드 디. 슈미트 | 열 가소성 중합체 물질 및 그의 제조방법 |
US5227182A (en) * | 1991-07-17 | 1993-07-13 | Wm. Wrigley Jr. Company | Method of controlling release of sucralose in chewing gum using cellulose derivatives and gum produced thereby |
US5169657A (en) * | 1991-07-17 | 1992-12-08 | Wm. Wrigley Jr. Company | Polyvinyl acetate encapsulation of sucralose from solutions for use in chewing gum |
NZ243667A (en) * | 1991-08-02 | 1995-02-24 | Kurihara Yoshie | Chewing gum containing coated curculin derivative or fruit containing curculin |
US5192561A (en) * | 1991-09-19 | 1993-03-09 | Wm. Wrigley Jr. Company | Aspartame stability in chewing gum using an acid gelatin system |
US5576042A (en) | 1991-10-25 | 1996-11-19 | Fuisz Technologies Ltd. | High intensity particulate polysaccharide based liquids |
EP0661966B1 (de) * | 1991-12-17 | 2000-07-19 | Biovail Technologies Ltd. | Zusammensetzung und verfahren zur ulcusprävention und -behandlung |
US5218020A (en) * | 1992-02-12 | 1993-06-08 | The Goodyear Tire & Rubber Company | Chitosan reinforced tires and method of incorporating chitosan into an elastomer |
US5654003A (en) * | 1992-03-05 | 1997-08-05 | Fuisz Technologies Ltd. | Process and apparatus for making tablets and tablets made therefrom |
US5288508A (en) * | 1992-03-20 | 1994-02-22 | Fuisz Technologies, Ltd. | Delivery systems containing elastomer solvents subjected to flash flow |
US5286502A (en) * | 1992-04-21 | 1994-02-15 | Wm. Wrigley Jr. Company | Use of edible film to prolong chewing gum shelf life |
US5728397A (en) * | 1992-05-12 | 1998-03-17 | Fuisz Technologies Ltd. | Polydextrose product and process |
US5279849A (en) * | 1992-05-12 | 1994-01-18 | Fuisz Technologies Ltd. | Dispersible polydextrose, compositions containing same and method for the preparation thereof |
CA2095776C (en) * | 1992-05-12 | 2007-07-10 | Richard C. Fuisz | Rapidly dispersable compositions containing polydextrose |
US5334397A (en) * | 1992-07-14 | 1994-08-02 | Amurol Products Company | Bubble gum formulation |
US5348758A (en) * | 1992-10-20 | 1994-09-20 | Fuisz Technologies Ltd. | Controlled melting point matrix formed with admixtures of a shearform matrix material and an oleaginous material |
US5380473A (en) * | 1992-10-23 | 1995-01-10 | Fuisz Technologies Ltd. | Process for making shearform matrix |
US5338809A (en) * | 1993-01-19 | 1994-08-16 | Nabisco, Inc. | Chewing gum or confection containing flavorant adsorbed on silica |
US5518551A (en) * | 1993-09-10 | 1996-05-21 | Fuisz Technologies Ltd. | Spheroidal crystal sugar and method of making |
US5622719A (en) * | 1993-09-10 | 1997-04-22 | Fuisz Technologies Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
US5597416A (en) * | 1993-10-07 | 1997-01-28 | Fuisz Technologies Ltd. | Method of making crystalline sugar and products resulting therefrom |
US5851553A (en) * | 1993-09-10 | 1998-12-22 | Fuisz Technologies, Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
US5895664A (en) * | 1993-09-10 | 1999-04-20 | Fuisz Technologies Ltd. | Process for forming quickly dispersing comestible unit and product therefrom |
US5346377A (en) * | 1993-10-07 | 1994-09-13 | Fuisz Technologies Ltd. | Apparatus for flash flow processing having feed rate control |
US5626892A (en) * | 1993-11-24 | 1997-05-06 | Nabisco, Inc. | Method for production of multi-flavored and multi-colored chewing gum |
US6020002A (en) * | 1994-06-14 | 2000-02-01 | Fuisz Technologies Ltd. | Delivery of controlled-release system(s) |
US5567439A (en) * | 1994-06-14 | 1996-10-22 | Fuisz Technologies Ltd. | Delivery of controlled-release systems(s) |
US5445769A (en) * | 1994-06-27 | 1995-08-29 | Fuisz Technologies Ltd. | Spinner head for flash flow processing |
US5582855A (en) | 1994-07-01 | 1996-12-10 | Fuisz Technologies Ltd. | Flash flow formed solloid delivery systems |
US5843922A (en) * | 1994-07-29 | 1998-12-01 | Fuisz Technologies Ltd. | Preparation of oligosaccharides and products therefrom |
US5556652A (en) | 1994-08-05 | 1996-09-17 | Fuisz Technologies Ltd. | Comestibles containing stabilized highly odorous flavor component delivery systems |
US5587198A (en) | 1995-05-31 | 1996-12-24 | Fuisz Technologies Ltd. | Positive hydration method of preparing confectionery and product therefrom |
US6472000B1 (en) | 1996-12-23 | 2002-10-29 | Wm. Wrigley Jr. Co. | Method of controlling release of bitterness inhibitors in chewing gum and gum produced thereby |
US20030180414A1 (en) * | 1996-11-27 | 2003-09-25 | Gudas Victor V. | Method of controlling release of bitterness inhibitors in chewing gum and gum produced thereby |
CA2271889C (en) * | 1996-11-27 | 2004-01-27 | Wm. Wrigley Jr. Company | Method of controlling release of caffeine in chewing gum and gum produced thereby |
US6949264B1 (en) | 1996-11-27 | 2005-09-27 | Wm. Wrigley Jr. Company | Nutraceuticals or nutritional supplements and method of making |
US6165516A (en) * | 1996-11-27 | 2000-12-26 | Wm. Wrigley Jr. Company | Method of controlling release of caffeine in chewing gum |
WO2000035298A1 (en) * | 1996-11-27 | 2000-06-22 | Wm. Wrigley Jr. Company | Chewing gum containing medicament active agents |
US6080432A (en) * | 1996-12-23 | 2000-06-27 | Wm. Wrigley Jr. Company | Chewing gum composition containing sodium glycinate and method of making a chewing gum product therefrom |
US6627233B1 (en) | 1997-09-18 | 2003-09-30 | Wm. Wrigley Jr. Company | Chewing gum containing physiological cooling agents |
RU2214721C2 (ru) * | 1997-09-18 | 2003-10-27 | Вм. Ригли Дж. Компани | Способ производства жевательной резинки с физиологическими охлаждающими агентами (варианты), жевательная резинка по этому способу, композиция охлаждающего ароматизирующего вещества, жевательная резинка, включающая эту композицию, покрытая жевательная резинка (варианты), способ усиления вкусового воздействия покрытой жевательной резинки, способ покрытия жевательной резинки, композиция жевательной резинки |
US6455080B1 (en) | 1997-12-29 | 2002-09-24 | Wm. Wrigley Jr., Company | Chewing gum containing controlled release acyclic carboxamide and method of making |
AU2002318866B2 (en) * | 1997-12-30 | 2005-12-22 | Wm. Wrigley Jr. Company | Method of Controlling Release of Antimicrobial Agents in Chewing Gum and Gum Produced Thereby |
EP1043937A4 (de) * | 1997-12-30 | 2004-05-12 | Wrigley W M Jun Co | Verfahren zur kontrollierten abgabe antimikrobieller mittel in kaugummi sowie dadurch hergestellter kaugummi |
US6592912B1 (en) * | 1997-12-30 | 2003-07-15 | Wm. Wrigley Jr. Company | Method of controlling release of antimicrobial agents from chewing gum and gum produced thereby |
AU2006203624B2 (en) * | 1998-06-05 | 2008-07-10 | Wm. Wrigley Jr. Company | Method of controlling release of N-substituted derivatives of aspartame in chewing gum and gum produced thereby |
DK1083799T3 (da) * | 1998-06-05 | 2011-01-10 | Wrigley W M Jun Co | Fremgangsmåde til kontrol af frigørelse af N-substituerede derivater af aspartam i tyggegummi og tyggegummi produceret dermed |
US6692778B2 (en) | 1998-06-05 | 2004-02-17 | Wm. Wrigley Jr. Company | Method of controlling release of N-substituted derivatives of aspartame in chewing gum |
US6531114B1 (en) | 1999-04-06 | 2003-03-11 | Wm. Wrigley Jr. Company | Sildenafil citrate chewing gum formulations and methods of using the same |
US7163705B2 (en) | 1998-12-15 | 2007-01-16 | Wm. Wrigley Jr. Company | Coated chewing gum product and method of making |
US6627234B1 (en) | 1998-12-15 | 2003-09-30 | Wm. Wrigley Jr. Company | Method of producing active agent coated chewing gum products |
BR9916302A (pt) * | 1998-12-15 | 2003-11-18 | Wrigley W M Jun Co | Liberação controlada de agentes ativos a partir de um revestimento de goma de mascar |
US6586023B1 (en) * | 1998-12-15 | 2003-07-01 | Wm. Wrigley Jr. Company | Process for controlling release of active agents from a chewing gum coating and product thereof |
PL350925A1 (en) | 1999-04-01 | 2003-02-10 | Wrigley W M Jun Co | Long flavor duration releasing structures for chewing gum |
US6355265B1 (en) | 1999-04-06 | 2002-03-12 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US6773716B2 (en) | 1999-04-06 | 2004-08-10 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US7935362B2 (en) | 1999-04-06 | 2011-05-03 | Wm. Wrigley Jr. Company | Over-coated product including consumable center and medicament |
US6322806B1 (en) | 1999-04-06 | 2001-11-27 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations including tableted center |
US6541048B2 (en) | 1999-09-02 | 2003-04-01 | Wm. Wrigley Jr. Company | Coated chewing gum products containing an acid blocker and process of preparing |
US6663849B1 (en) | 2000-09-01 | 2003-12-16 | Wm. Wrigley Jr. Company | Antacid chewing gum products coated with high viscosity materials |
US6645535B2 (en) | 1999-09-02 | 2003-11-11 | Wm. Wrigley Jr. Company | Method of making coated chewing gum products containing various antacids |
US6569472B1 (en) | 2000-09-01 | 2003-05-27 | Wm. Wrigley Jr. Company | Coated chewing gum products containing antacid and method of making |
AU3885201A (en) | 1999-09-20 | 2001-04-24 | Mastercare | Diet and weight control gum and sucker |
US9387168B2 (en) | 1999-09-20 | 2016-07-12 | Jack Barreca | Chewing gum with tomatidine |
US9253991B2 (en) | 1999-09-20 | 2016-02-09 | Jack Barreca | Chewing gum with B vitamins |
CN1158936C (zh) * | 1999-12-30 | 2004-07-28 | Wm.雷格利Jr.公司 | 自口香糖中的亲脂活性剂释放 |
US7115288B2 (en) | 2000-06-09 | 2006-10-03 | Wm. Wrigley Jr. Company | Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener |
US6572900B1 (en) | 2000-06-09 | 2003-06-03 | Wm. Wrigley, Jr. Company | Method for making coated chewing gum products including a high-intensity sweetener |
US6444241B1 (en) | 2000-08-30 | 2002-09-03 | Wm. Wrigley Jr. Company | Caffeine coated chewing gum product and process of making |
EP1349459A4 (de) | 2000-12-15 | 2006-09-13 | Wrigley W M Jun Co | Eingekapselte säuremischungen und sie enthaltende produkte |
US6579545B2 (en) | 2000-12-22 | 2003-06-17 | Wm. Wrigley Jr. Company | Coated chewing gum products containing an antigas agent |
US6773733B2 (en) * | 2001-03-26 | 2004-08-10 | Loders Croklaan Usa Llc | Structured particulate systems |
US6673383B2 (en) * | 2001-03-26 | 2004-01-06 | Unilever Patent Holdings Bv | Method for improving the performance of a food product |
US7445769B2 (en) | 2002-10-31 | 2008-11-04 | Cadbury Adams Usa Llc | Compositions for removing stains from dental surfaces and methods of making and using the same |
US8367047B2 (en) * | 2002-12-20 | 2013-02-05 | L'oreal | Hair compositions |
US20050008747A1 (en) * | 2003-07-11 | 2005-01-13 | Barkalow David G. | Method of forming a sugarless coating on chewing gum |
US7390518B2 (en) | 2003-07-11 | 2008-06-24 | Cadbury Adams Usa, Llc | Stain removing chewing gum composition |
US8591973B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for active components and a material having preselected hydrophobicity as part of an edible composition |
US8389032B2 (en) | 2005-05-23 | 2013-03-05 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition having selected particle size |
US8591974B2 (en) * | 2003-11-21 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for two or more active components as part of an edible composition |
US8591972B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for coated active components as part of an edible composition |
US8597703B2 (en) | 2005-05-23 | 2013-12-03 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component |
US8591968B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Edible composition including a delivery system for active components |
US9271904B2 (en) | 2003-11-21 | 2016-03-01 | Intercontinental Great Brands Llc | Controlled release oral delivery systems |
US20050112236A1 (en) | 2003-11-21 | 2005-05-26 | Navroz Boghani | Delivery system for active components as part of an edible composition having preselected tensile strength |
US8389031B2 (en) | 2005-05-23 | 2013-03-05 | Kraft Foods Global Brands Llc | Coated delivery system for active components as part of an edible composition |
US7641892B2 (en) | 2004-07-29 | 2010-01-05 | Cadburry Adams USA, LLC | Tooth whitening compositions and delivery systems therefor |
US7727565B2 (en) | 2004-08-25 | 2010-06-01 | Cadbury Adams Usa Llc | Liquid-filled chewing gum composition |
US20060068058A1 (en) * | 2004-09-30 | 2006-03-30 | Cadbury Adams Usa Llc | Thermally stable, high tensile strength encapsulation compositions for actives |
US7955630B2 (en) | 2004-09-30 | 2011-06-07 | Kraft Foods Global Brands Llc | Thermally stable, high tensile strength encapsulated actives |
US20080274183A1 (en) * | 2005-02-04 | 2008-11-06 | Phillip Michael Cook | Thermoplastic articles containing a medicament |
US9198448B2 (en) | 2005-02-07 | 2015-12-01 | Intercontinental Great Brands Llc | Stable tooth whitening gum with reactive ingredients |
US20060204613A1 (en) * | 2005-02-18 | 2006-09-14 | Castro Armando J | Chewing gum containing flavor delivery systems |
US20060286200A1 (en) * | 2005-04-18 | 2006-12-21 | Castro Armando J | Confections containing flavor delivery systems |
CA2604760C (en) | 2005-05-23 | 2012-06-26 | Cadbury Adams Usa Llc | Taste potentiator compositions and beverages containing same |
US7851005B2 (en) | 2005-05-23 | 2010-12-14 | Cadbury Adams Usa Llc | Taste potentiator compositions and beverages containing same |
US7851006B2 (en) | 2005-05-23 | 2010-12-14 | Cadbury Adams Usa Llc | Taste potentiator compositions and beverages containing same |
US20070042078A1 (en) * | 2005-08-22 | 2007-02-22 | Cadbury Adams Usa Llc | Biodegradable chewing gum |
PL1978817T3 (pl) * | 2006-02-03 | 2018-01-31 | Wrigley W M Jun Co | Sole fosforanowe wapnia w kompozycjach doustnych użyteczne jako środek do remineralizacji zębów |
US20070218165A1 (en) * | 2006-03-15 | 2007-09-20 | Wm. Wrigley Jr. Company | Confectionery compositions using nanomaterials |
CN101415336A (zh) * | 2006-03-31 | 2009-04-22 | Wm.雷格利Jr.公司 | 长持续时间包封调味剂和使用该调味剂的口香糖 |
PL2026747T3 (pl) * | 2006-05-25 | 2016-07-29 | Wrigley W M Jun Co | Doustne kompozycje zapewniające polepszone usuwanie przebarwień nazębnych |
EP1862793A1 (de) * | 2006-05-29 | 2007-12-05 | Biotest AG | Teilchenzähler mit hoher Durchlaufleistung |
EP2083638B1 (de) * | 2006-10-31 | 2010-10-06 | WM. Wrigley Jr., Company | Geschmacksfreisetzende kerne und ihre verwendung bei kaugummi |
US9120963B2 (en) * | 2006-11-08 | 2015-09-01 | Schlumberger Technology Corporation | Delayed water-swelling materials and methods of use |
WO2009070570A1 (en) * | 2007-11-29 | 2009-06-04 | Cadbury Adams Usa Llc | Multi-region chewing gum with actives |
RU2496977C2 (ru) * | 2008-02-27 | 2013-10-27 | Шлюмберже Текнолоджи Б.В. | Способ улучшения обработки подземного пласта через скважину и способ гидроразрыва пласта через скважину |
PL2597967T3 (pl) | 2010-07-30 | 2015-10-30 | Intercontinental Great Brands Llc | System dostarczania składników aktywnych jako część kompozycji spożywczej |
ES2656944T3 (es) | 2011-04-29 | 2018-03-01 | Intercontinental Great Brands Llc | Ácido encapsulado, método de preparación del mismo, y goma de mascar que lo comprende |
CN103040090B (zh) | 2012-01-20 | 2016-03-30 | 奥驰亚客户服务公司 | 脱除烟草的口腔用产品 |
CN102754907B (zh) | 2012-01-20 | 2015-06-24 | 奥驰亚客户服务公司 | 口腔用产品 |
CN102754908B (zh) | 2012-01-20 | 2015-06-10 | 奥驰亚客户服务公司 | 口腔用烟草产品 |
CN103039688B (zh) * | 2012-01-20 | 2016-01-06 | 奥驰亚客户服务公司 | 口腔用产品 |
US9854831B2 (en) | 2012-01-20 | 2018-01-02 | Altria Client Services Llc | Oral product |
KR102373049B1 (ko) * | 2013-12-20 | 2022-03-11 | 필립모리스 프로덕츠 에스.에이. | 왁스로 캡슐화된 담배용 제올라이트 향미 전달 시스템 |
JP6636528B2 (ja) | 2015-01-29 | 2020-01-29 | インターコンチネンタル グレート ブランズ エルエルシー | 食用組成物中の1種又はそれ以上の有効成分の送達システムを調製するための方法 |
DE102016203008A1 (de) * | 2016-02-25 | 2017-08-31 | Wacker Chemie Ag | Verkapselte Süßstoffe und Verfahren zur ihrer Herstellung |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL125158C (de) * | 1959-10-01 | |||
US3201353A (en) * | 1960-06-14 | 1965-08-17 | American Agricultural Chem Co | Micro-inclusions and method of making same |
US3329574A (en) * | 1965-04-12 | 1967-07-04 | Schwarz Biores Inc | Method and material for selective diffusion |
US3435110A (en) * | 1966-03-21 | 1969-03-25 | Ethicon Inc | Collagen fibril matrix pharmaceuticals |
DE2037947C3 (de) * | 1969-08-01 | 1983-01-13 | Bush Boake Allen Ltd., London | Eingekapselte Zubereitungen |
US3795744A (en) * | 1970-10-21 | 1974-03-05 | Lotte Co Ltd | Flavor variable chewing gum and methods of preparing the same |
US3737521A (en) * | 1970-12-09 | 1973-06-05 | Goodrich Co B F | Formulation for sustained release of a biological agent |
US3951821A (en) * | 1972-07-14 | 1976-04-20 | The Dow Chemical Company | Disintegrating agent for tablets |
US4206301A (en) * | 1972-09-28 | 1980-06-03 | Seymour Yolles | Sustained flavor release composition |
US3818107A (en) * | 1972-09-28 | 1974-06-18 | Brook D | Chewing gum with sustained flavor release compositions |
US3928633A (en) * | 1973-12-03 | 1975-12-23 | Gen Foods Corp | Sweetening composition and process therefor |
US3923939A (en) * | 1974-06-07 | 1975-12-02 | Alza Corp | Process for improving release kinetics of a monolithic drug delivery device |
US4125519A (en) * | 1976-10-13 | 1978-11-14 | Murray Goodman | Polypeptides containing 3,4-dihydroxyphenylalanine |
US4122195A (en) * | 1977-01-24 | 1978-10-24 | General Foods Corporation | Fixation of APM in chewing gum |
US4230687A (en) * | 1978-05-30 | 1980-10-28 | Griffith Laboratories U.S.A., Inc. | Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices |
US4374858A (en) * | 1979-10-04 | 1983-02-22 | Warner-Lambert Company | Aspartame sweetened chewing gum of improved sweetness stability |
PT72939B (en) * | 1980-05-08 | 1983-01-13 | Merck & Co Inc | Process for preparing calcium alginate fibres |
US4384005A (en) * | 1980-09-26 | 1983-05-17 | General Foods Corporation | Non-friable, readily-soluble, compressed tablets and process for preparing same |
US4447475A (en) * | 1980-12-03 | 1984-05-08 | Ici Australia Limited | Process for composite polymer beads |
US4496596A (en) * | 1980-12-29 | 1985-01-29 | General Foods Corporation | Aromatizing method |
US4384004A (en) * | 1981-06-02 | 1983-05-17 | Warner-Lambert Company | Encapsulated APM and method of preparation |
US4388328A (en) * | 1981-10-15 | 1983-06-14 | Warner-Lambert Company | Sorbitol containing mixture encapsulated flavor |
US4386106A (en) * | 1981-12-01 | 1983-05-31 | Borden, Inc. | Process for preparing a time delayed release flavorant and an improved flavored chewing gum composition |
US4515769A (en) * | 1981-12-01 | 1985-05-07 | Borden, Inc. | Encapsulated flavorant material, method for its preparation, and food and other compositions incorporating same |
JPS5966841A (ja) * | 1982-10-05 | 1984-04-16 | Meiji Seika Kaisha Ltd | 複合繊維状チユ−インガムの製造方法 |
US4673577A (en) * | 1983-02-18 | 1987-06-16 | Wm. Wrigley Jr. Company | Shellac encapsulant for high-potency sweeteners in chewing gum |
US4485118A (en) * | 1983-04-21 | 1984-11-27 | Warner-Lambert Company | Gum composition with plural time releasing flavors and method of preparation |
US4568560A (en) * | 1984-03-16 | 1986-02-04 | Warner-Lambert Company | Encapsulated fragrances and flavors and process therefor |
US4590075A (en) * | 1984-08-27 | 1986-05-20 | Warner-Lambert Company | Elastomer encapsulation of flavors and sweeteners, long lasting flavored chewing gum compositions based thereon and process of preparation |
US4752485A (en) * | 1984-10-05 | 1988-06-21 | Warner-Lambert Company | Novel sweetener delivery systems |
US4606940A (en) * | 1984-12-21 | 1986-08-19 | The Ohio State University Research Foundation | Small particle formation and encapsulation |
US4720384A (en) * | 1985-05-03 | 1988-01-19 | E. I. Du Pont De Nemours And Company | Manufacture of hollow fine tubular drug delivery systems |
US4673565A (en) * | 1985-05-03 | 1987-06-16 | E. I. Du Pont De Nemours And Company | Pharmaceutical compositions containing hollow fine tubular drug delivery systems |
US4695463A (en) * | 1985-05-24 | 1987-09-22 | Warner-Lambert Company | Delivery system for active ingredients and preparation thereof |
US4634593A (en) * | 1985-07-31 | 1987-01-06 | Nabisco Brands, Inc. | Composition and method for providing controlled release of sweetener in confections |
US4766036A (en) * | 1985-09-16 | 1988-08-23 | The Dow Chemical Company | Process for producing porous fibers from orientable olefin polymers having cation-containing, pendent reactive side-groups and the resultant product |
US4690825A (en) * | 1985-10-04 | 1987-09-01 | Advanced Polymer Systems, Inc. | Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be prepared by a process utilizing the active ingredient as a porogen |
US4740376A (en) * | 1986-01-07 | 1988-04-26 | Warner-Lambert Company | Encapsulation composition for use with chewing gum and edible products |
US4711784A (en) * | 1986-01-07 | 1987-12-08 | Warner-Lambert Company | Encapsulation composition for use with chewing gum and edible products |
AU7472687A (en) * | 1986-06-25 | 1988-01-07 | Nabisco Brands Incorporated | Encapsulated active comestible ingredients |
US4726953A (en) * | 1986-10-01 | 1988-02-23 | Nabisco Brands, Inc. | Sweet flavorful soft flexible sugarless chewing gum |
US4816265A (en) * | 1986-12-23 | 1989-03-28 | Warner-Lambert Company | Sweetener delivery systems containing polyvinyl acetate |
US4722845A (en) * | 1986-12-23 | 1988-02-02 | Warner-Lambert Company | Stable cinnamon-flavored chewing gum composition |
US4855326A (en) * | 1987-04-20 | 1989-08-08 | Fuisz Pharmaceutical Ltd. | Rapidly dissoluble medicinal dosage unit and method of manufacture |
US4975270A (en) * | 1987-04-21 | 1990-12-04 | Nabisco Brands, Inc. | Elastomer encased active ingredients |
AU3542089A (en) * | 1989-03-28 | 1990-06-26 | Wm. Wrigley Jr. Company | Method of controlling release of alitame in chewing gum and gum produced thereby |
AU3056389A (en) * | 1989-12-09 | 1989-05-02 | Wm. Wrigley Jr. Company | Method of controlling release of acesulfame k in chewing gum and gum produced thereby |
-
1989
- 1989-04-19 US US07/340,384 patent/US4978537A/en not_active Expired - Lifetime
- 1989-09-26 CA CA000613119A patent/CA1335763C/en not_active Expired - Lifetime
-
1990
- 1990-01-24 NZ NZ232236A patent/NZ232236A/xx unknown
- 1990-01-26 ES ES90902500T patent/ES2045906T3/es not_active Expired - Lifetime
- 1990-01-26 DE DE90902500T patent/DE69004047T2/de not_active Expired - Lifetime
- 1990-01-26 WO PCT/US1990/000430 patent/WO1990012511A1/en active IP Right Grant
- 1990-01-26 EP EP90902500A patent/EP0423255B1/de not_active Expired - Lifetime
- 1990-01-26 AU AU50214/90A patent/AU619152B2/en not_active Expired
- 1990-01-26 DK DK90902500.9T patent/DK0423255T3/da active
- 1990-01-26 JP JP2502900A patent/JPH0751049B2/ja not_active Expired - Lifetime
- 1990-01-26 AT AT90902500T patent/ATE95983T1/de active
- 1990-01-30 PH PH39968A patent/PH26002A/en unknown
- 1990-03-19 CN CN90101542A patent/CN1054884A/zh active Pending
- 1990-12-18 FI FI906250A patent/FI906250A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69004047T2 (de) | 1994-02-10 |
CA1335763C (en) | 1995-06-06 |
DE69004047D1 (de) | 1993-11-25 |
AU5021490A (en) | 1990-11-16 |
EP0423255A1 (de) | 1991-04-24 |
JPH03505282A (ja) | 1991-11-21 |
ATE95983T1 (de) | 1993-11-15 |
DK0423255T3 (da) | 1993-12-13 |
CN1054884A (zh) | 1991-10-02 |
WO1990012511A1 (en) | 1990-11-01 |
FI906250A0 (fi) | 1990-12-18 |
EP0423255B1 (de) | 1993-10-20 |
US4978537A (en) | 1990-12-18 |
AU619152B2 (en) | 1992-01-16 |
EP0423255A4 (en) | 1991-10-02 |
NZ232236A (en) | 1991-10-25 |
JPH0751049B2 (ja) | 1995-06-05 |
ES2045906T3 (es) | 1994-01-16 |
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