PH25902A - 1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics - Google Patents

1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics

Info

Publication number
PH25902A
PH25902A PH36317A PH36317A PH25902A PH 25902 A PH25902 A PH 25902A PH 36317 A PH36317 A PH 36317A PH 36317 A PH36317 A PH 36317A PH 25902 A PH25902 A PH 25902A
Authority
PH
Philippines
Prior art keywords
indoles
analgesics
morpholinyl
alkyl
useful
Prior art date
Application number
PH36317A
Other languages
English (en)
Inventor
Thomas Edward D Ambra
Malcolm Rice Bell
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of PH25902A publication Critical patent/PH25902A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH36317A 1987-02-11 1988-01-04 1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics PH25902A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/013,313 US4840950A (en) 1987-02-11 1987-02-11 4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles

Publications (1)

Publication Number Publication Date
PH25902A true PH25902A (en) 1991-12-19

Family

ID=21759325

Family Applications (1)

Application Number Title Priority Date Filing Date
PH36317A PH25902A (en) 1987-02-11 1988-01-04 1-[4-morpholinyl)alkyl-1-N-indoles which are useful as analgesics

Country Status (21)

Country Link
US (1) US4840950A (el)
EP (1) EP0278265B1 (el)
JP (1) JP2561939B2 (el)
KR (1) KR960007523B1 (el)
AR (1) AR243184A1 (el)
AT (1) ATE80386T1 (el)
AU (1) AU596494B2 (el)
CA (1) CA1299180C (el)
DE (1) DE3874361T2 (el)
DK (1) DK167921B1 (el)
ES (1) ES2052608T3 (el)
FI (1) FI88152C (el)
GR (1) GR3005855T3 (el)
IE (1) IE63264B1 (el)
IL (1) IL84922A (el)
MX (1) MX174421B (el)
NO (1) NO169713C (el)
NZ (1) NZ223146A (el)
PH (1) PH25902A (el)
PT (1) PT86527B (el)
ZA (1) ZA879723B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5081122A (en) * 1990-03-05 1992-01-14 Sterling Drug Inc. Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
EP2865381A1 (en) 2006-05-18 2015-04-29 Pharmacyclics, Inc. ITK inhibitors for treating blood cell malignancies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3215699A (en) * 1961-06-27 1965-11-02 Warner Lambert Pharmaceutical Substituted acetylphenyl hydrazones of 2,3-piperidine diones
US3182071A (en) * 1961-06-27 1965-05-04 Warner Lambert Pharmaceutical Acylated indole derivatives
US3489429A (en) * 1967-12-18 1970-01-13 American Home Prod 1-loweralkanoyl-3-(2-substituted ethyl)indoles
GB1374414A (en) * 1972-06-12 1974-11-20 Sterling Drug Inc 1-acyl-3-amino-alkyl-indoles and their preparation
GB1436771A (en) * 1973-02-16 1976-05-26 Labaz Indole derivatives and process for preparing the same
US4581354A (en) * 1984-08-06 1986-04-08 Sterling Drug Inc. 3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
PH23498A (en) * 1984-08-06 1989-08-16 Sterling Drug Inc 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof

Also Published As

Publication number Publication date
AU596494B2 (en) 1990-05-03
FI88152C (fi) 1993-04-13
ZA879723B (en) 1988-06-23
DK21588D0 (da) 1988-01-19
AR243184A1 (es) 1993-07-30
DK21588A (da) 1988-08-12
IE63264B1 (en) 1995-04-05
IL84922A0 (en) 1988-06-30
ES2052608T3 (es) 1994-07-16
NO880206L (no) 1988-08-12
NZ223146A (en) 1990-01-29
IL84922A (en) 1992-03-29
DK167921B1 (da) 1994-01-03
DE3874361D1 (de) 1992-10-15
FI88152B (fi) 1992-12-31
JP2561939B2 (ja) 1996-12-11
CA1299180C (en) 1992-04-21
KR960007523B1 (ko) 1996-06-05
NO169713C (no) 1992-07-29
EP0278265A1 (en) 1988-08-17
JPS63216865A (ja) 1988-09-09
KR880009962A (ko) 1988-10-06
AU1038788A (en) 1988-08-18
FI880117A (fi) 1988-08-12
GR3005855T3 (el) 1993-06-07
PT86527B (pt) 1991-12-31
EP0278265B1 (en) 1992-09-09
NO880206D0 (no) 1988-01-19
DE3874361T2 (de) 1993-03-25
FI880117A0 (fi) 1988-01-12
MX174421B (es) 1994-05-16
ATE80386T1 (de) 1992-09-15
IE880047L (en) 1988-08-11
MX10085A (es) 1993-09-01
US4840950A (en) 1989-06-20
NO169713B (no) 1992-04-21
PT86527A (en) 1988-02-01

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