AR243184A1 - Procedimiento para preparar 1-(4-morfolinil) alquil-1h-indoles. - Google Patents

Procedimiento para preparar 1-(4-morfolinil) alquil-1h-indoles.

Info

Publication number
AR243184A1
AR243184A1 AR88309876A AR30987688A AR243184A1 AR 243184 A1 AR243184 A1 AR 243184A1 AR 88309876 A AR88309876 A AR 88309876A AR 30987688 A AR30987688 A AR 30987688A AR 243184 A1 AR243184 A1 AR 243184A1
Authority
AR
Argentina
Prior art keywords
analgesics
morpholinyl
alkyl
preparation
indoles useful
Prior art date
Application number
AR88309876A
Other languages
English (en)
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Application granted granted Critical
Publication of AR243184A1 publication Critical patent/AR243184A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AR88309876A 1987-02-11 1988-01-20 Procedimiento para preparar 1-(4-morfolinil) alquil-1h-indoles. AR243184A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/013,313 US4840950A (en) 1987-02-11 1987-02-11 4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles

Publications (1)

Publication Number Publication Date
AR243184A1 true AR243184A1 (es) 1993-07-30

Family

ID=21759325

Family Applications (1)

Application Number Title Priority Date Filing Date
AR88309876A AR243184A1 (es) 1987-02-11 1988-01-20 Procedimiento para preparar 1-(4-morfolinil) alquil-1h-indoles.

Country Status (21)

Country Link
US (1) US4840950A (es)
EP (1) EP0278265B1 (es)
JP (1) JP2561939B2 (es)
KR (1) KR960007523B1 (es)
AR (1) AR243184A1 (es)
AT (1) ATE80386T1 (es)
AU (1) AU596494B2 (es)
CA (1) CA1299180C (es)
DE (1) DE3874361T2 (es)
DK (1) DK167921B1 (es)
ES (1) ES2052608T3 (es)
FI (1) FI88152C (es)
GR (1) GR3005855T3 (es)
IE (1) IE63264B1 (es)
IL (1) IL84922A (es)
MX (1) MX174421B (es)
NO (1) NO169713C (es)
NZ (1) NZ223146A (es)
PH (1) PH25902A (es)
PT (1) PT86527B (es)
ZA (1) ZA879723B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5081122A (en) * 1990-03-05 1992-01-14 Sterling Drug Inc. Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
EP2027087A2 (en) 2006-05-18 2009-02-25 MannKind Corporation Intracellular kinase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3182071A (en) * 1961-06-27 1965-05-04 Warner Lambert Pharmaceutical Acylated indole derivatives
US3215699A (en) * 1961-06-27 1965-11-02 Warner Lambert Pharmaceutical Substituted acetylphenyl hydrazones of 2,3-piperidine diones
US3481953A (en) * 1967-12-18 1969-12-02 American Home Prod 1-arylsulfonyl-3-(2-substituted ethyl) indoles
GB1374414A (en) * 1972-06-12 1974-11-20 Sterling Drug Inc 1-acyl-3-amino-alkyl-indoles and their preparation
GB1436771A (en) * 1973-02-16 1976-05-26 Labaz Indole derivatives and process for preparing the same
US4581354A (en) * 1984-08-06 1986-04-08 Sterling Drug Inc. 3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
PH23498A (en) * 1984-08-06 1989-08-16 Sterling Drug Inc 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof

Also Published As

Publication number Publication date
NO880206L (no) 1988-08-12
MX10085A (es) 1993-09-01
JP2561939B2 (ja) 1996-12-11
EP0278265A1 (en) 1988-08-17
JPS63216865A (ja) 1988-09-09
DK21588D0 (da) 1988-01-19
ZA879723B (en) 1988-06-23
ES2052608T3 (es) 1994-07-16
DK167921B1 (da) 1994-01-03
IE880047L (en) 1988-08-11
DE3874361D1 (de) 1992-10-15
CA1299180C (en) 1992-04-21
DK21588A (da) 1988-08-12
IE63264B1 (en) 1995-04-05
GR3005855T3 (es) 1993-06-07
FI880117A0 (fi) 1988-01-12
PT86527A (en) 1988-02-01
KR880009962A (ko) 1988-10-06
EP0278265B1 (en) 1992-09-09
NZ223146A (en) 1990-01-29
US4840950A (en) 1989-06-20
MX174421B (es) 1994-05-16
FI88152C (fi) 1993-04-13
ATE80386T1 (de) 1992-09-15
AU1038788A (en) 1988-08-18
DE3874361T2 (de) 1993-03-25
IL84922A0 (en) 1988-06-30
NO880206D0 (no) 1988-01-19
AU596494B2 (en) 1990-05-03
FI88152B (fi) 1992-12-31
PH25902A (en) 1991-12-19
IL84922A (en) 1992-03-29
KR960007523B1 (ko) 1996-06-05
NO169713C (no) 1992-07-29
FI880117A (fi) 1988-08-12
NO169713B (no) 1992-04-21
PT86527B (pt) 1991-12-31

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