PH25571A - Alpha'-alkyl-4-amino-3-quinolinemethanols, 1-(4-aralkylamino-3-quinolinyl) alaknones, their use as medicaments - Google Patents

Alpha'-alkyl-4-amino-3-quinolinemethanols, 1-(4-aralkylamino-3-quinolinyl) alaknones, their use as medicaments

Info

Publication number
PH25571A
PH25571A PH35724A PH35724A PH25571A PH 25571 A PH25571 A PH 25571A PH 35724 A PH35724 A PH 35724A PH 35724 A PH35724 A PH 35724A PH 25571 A PH25571 A PH 25571A
Authority
PH
Philippines
Prior art keywords
loweralkyl
hydrogen
alaknones
quinolinemethanols
aralkylamino
Prior art date
Application number
PH35724A
Other languages
English (en)
Inventor
Richard Charles Effland
Joseph Thomas Klein
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PH25571A publication Critical patent/PH25571A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PH35724A 1986-08-25 1987-08-24 Alpha'-alkyl-4-amino-3-quinolinemethanols, 1-(4-aralkylamino-3-quinolinyl) alaknones, their use as medicaments PH25571A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/899,584 US4789678A (en) 1986-08-25 1986-08-25 Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Publications (1)

Publication Number Publication Date
PH25571A true PH25571A (en) 1991-08-08

Family

ID=25411249

Family Applications (1)

Application Number Title Priority Date Filing Date
PH35724A PH25571A (en) 1986-08-25 1987-08-24 Alpha'-alkyl-4-amino-3-quinolinemethanols, 1-(4-aralkylamino-3-quinolinyl) alaknones, their use as medicaments

Country Status (19)

Country Link
US (1) US4789678A (fi)
EP (1) EP0258755B1 (fi)
JP (1) JPS6360968A (fi)
KR (1) KR880002834A (fi)
AT (2) ATE67189T1 (fi)
AU (1) AU589029B2 (fi)
CA (1) CA1297111C (fi)
DE (1) DE3772905D1 (fi)
DK (1) DK441187A (fi)
ES (1) ES2029812T3 (fi)
FI (1) FI86299C (fi)
GR (1) GR3003299T3 (fi)
HU (1) HU199425B (fi)
IL (1) IL83629A (fi)
NO (1) NO873568L (fi)
NZ (1) NZ221543A (fi)
PH (1) PH25571A (fi)
PT (1) PT85583B (fi)
ZA (1) ZA876254B (fi)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581382B1 (fr) * 1985-05-06 1987-06-26 Sanofi Sa Derives n-(quinolyl) glycinamides, leur procede de preparation et leur application therapeutique en tant que psychotropes
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
US4743601A (en) * 1987-07-13 1988-05-10 Hoechst-Roussel Pharmaceuticals Inc. Dihydro-1,4-oxazino(2,3-C)quinolines
US4942168A (en) * 1987-07-13 1990-07-17 Hoechst-Roussel Pharmaceuticals Inc. Hydroxyquinoline amines, and method of enhancing memory in mammals
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
EP0361489A3 (en) * 1988-09-30 1991-06-12 Chugai Seiyaku Kabushiki Kaisha Novel 3,4-diaminoquinoline and pyridine compounds
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5110815A (en) * 1990-12-03 1992-05-05 Hoechst-Roussel Pharmaceuticals Inc. 5-amino-5,6,7,8-tetrahydroquinolines and related compounds and pharmaceutical use
GB9122051D0 (en) * 1991-10-17 1991-11-27 Univ Nottingham Medicines
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
HUP0203045A3 (en) * 1999-09-22 2004-06-28 Sanofi Aventis Deutschland 4-benzylaminoquinoline conjugates with bile acid and their heteroanalogues, methods for producing the same, medicaments containing these compounds and their use
US8420670B2 (en) 2007-08-22 2013-04-16 Abbott Laboratories 4-benzylaminoquinolines, pharmaceutical compositions containing them, and their use in therapy
JP5554319B2 (ja) 2008-04-01 2014-07-23 アボット ゲーエムベーハー ウント カンパニー カーゲー テトラヒドロイソキノリン類、それを含む医薬組成物および治療におけるそれの使用
AR075442A1 (es) 2009-02-16 2011-03-30 Abbott Gmbh & Co Kg Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
US8877794B2 (en) 2010-08-13 2014-11-04 Abbott Laboratories Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US8883839B2 (en) 2010-08-13 2014-11-11 Abbott Laboratories Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 (en) 2010-08-13 2015-06-09 AbbVie Deutschland GmbH & Co. KG Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8846743B2 (en) 2010-08-13 2014-09-30 Abbott Laboratories Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9045459B2 (en) 2010-08-13 2015-06-02 AbbVie Deutschland GmbH & Co. KG Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9309200B2 (en) 2011-05-12 2016-04-12 AbbVie Deutschland GmbH & Co. KG Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
JP2014521682A (ja) 2011-08-05 2014-08-28 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー アミノクロマン、アミノチオクロマンおよびアミノ−１，２，３，４−テトラヒドロキノリン誘導体、これらを含有する医薬組成物、ならびに治療におけるこれらの使用
JP2014533675A (ja) 2011-11-18 2014-12-15 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー Ｎ置換アミノベンゾシクロヘプテン、アミノテトラリン、アミノインダンおよびフェナルキルアミン誘導体、これらを含有する医薬組成物、および治療におけるこれらの使用
US9365512B2 (en) 2012-02-13 2016-06-14 AbbVie Deutschland GmbH & Co. KG Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en) 2013-03-15 2017-05-23 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9650334B2 (en) 2013-03-15 2017-05-16 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
CN105764895A (zh) 2013-10-17 2016-07-13 艾伯维德国有限责任两合公司 氨基四氢化萘及氨基二氢化茚衍生物，包含其的药物组合物及其在治疗中的用途
CN105992764A (zh) 2013-10-17 2016-10-05 艾伯维德国有限责任两合公司 氨基色满、氨基硫代色满及氨基-1,2,3,4-四氢喹啉衍生物，包含其的药物组合物及其在治疗中的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785165A (en) * 1953-12-22 1957-03-12 Abbott Lab Preparation of 4-aminoquinoline
US3391146A (en) * 1964-11-10 1968-07-02 Bristol Myers Co Nu-substituted carbamates and thiocarbamates of 2-quinolinemethanols
US4180670A (en) * 1977-02-02 1979-12-25 John Wyeth & Brother Limited Amino pyridine derivatives
FR2498187A1 (fr) * 1981-01-16 1982-07-23 Rhone Poulenc Sante Procede de preparation d'amino-4 chloro-7 quinoleines
EP0179383B1 (en) * 1984-10-25 1991-05-29 Hoechst-Roussel Pharmaceuticals Incorporated 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments
US4631286A (en) * 1984-10-25 1986-12-23 Hoechst-Roussel Pharmaceuticals Inc. 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US4695573A (en) * 1984-10-25 1987-09-22 Hoechst-Roussel Pharmaceuticals Inc. 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
US4816456A (en) * 1986-10-01 1989-03-28 Summers William K Administration of monoamine acridines in cholinergic neuronal deficit states

Also Published As

Publication number Publication date
AU589029B2 (en) 1989-09-28
FI86299B (fi) 1992-04-30
ZA876254B (en) 1988-04-27
EP0258755A1 (en) 1988-03-09
FI86299C (fi) 1992-08-10
ES2029812T3 (es) 1992-10-01
NZ221543A (en) 1990-09-26
PT85583A (en) 1987-09-01
IL83629A0 (en) 1988-01-31
GR3003299T3 (en) 1993-02-17
DE3772905D1 (de) 1991-10-17
FI873631A (fi) 1988-02-26
AU7734387A (en) 1988-02-25
PT85583B (pt) 1990-05-31
DK441187D0 (da) 1987-08-24
DK441187A (da) 1988-02-26
ATA260187A (de) 1989-01-15
US4789678A (en) 1988-12-06
ATE67189T1 (de) 1991-09-15
NO873568D0 (no) 1987-08-24
EP0258755B1 (en) 1991-09-11
JPS6360968A (ja) 1988-03-17
HU199425B (en) 1990-02-28
HUT45503A (en) 1988-07-28
KR880002834A (ko) 1988-05-11
FI873631A0 (fi) 1987-08-21
AT388729B (de) 1989-08-25
NO873568L (no) 1988-02-26
IL83629A (en) 1992-02-16
CA1297111C (en) 1992-03-10

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