PH24761A - Novel xanthine derivatives - Google Patents
Novel xanthine derivativesInfo
- Publication number
- PH24761A PH24761A PH35741A PH35741A PH24761A PH 24761 A PH24761 A PH 24761A PH 35741 A PH35741 A PH 35741A PH 35741 A PH35741 A PH 35741A PH 24761 A PH24761 A PH 24761A
- Authority
- PH
- Philippines
- Prior art keywords
- xanthine derivatives
- novel xanthine
- novel
- derivatives
- xanthine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/12—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1, 3, and 7, e.g. caffeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868620825A GB8620825D0 (en) | 1986-08-28 | 1986-08-28 | Organic compounds |
| GB878702129A GB8702129D0 (en) | 1987-01-30 | 1987-01-30 | Organic compounds |
| GB878703435A GB8703435D0 (en) | 1987-02-13 | 1987-02-13 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH24761A true PH24761A (en) | 1990-10-01 |
Family
ID=27263135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH35741A PH24761A (en) | 1986-08-28 | 1987-08-27 | Novel xanthine derivatives |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0258191B1 (es) |
| JP (1) | JPH0631236B2 (es) |
| KR (1) | KR880002870A (es) |
| AU (1) | AU600021B2 (es) |
| CA (1) | CA1289954C (es) |
| DE (1) | DE3779374D1 (es) |
| DK (1) | DK169337B1 (es) |
| ES (1) | ES2033922T3 (es) |
| FI (1) | FI87356C (es) |
| GR (1) | GR3004747T3 (es) |
| HU (1) | HU199840B (es) |
| IE (1) | IE60512B1 (es) |
| IL (1) | IL83659A (es) |
| MY (1) | MY101830A (es) |
| NZ (1) | NZ221571A (es) |
| PH (1) | PH24761A (es) |
| PT (1) | PT85594B (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9020921D0 (en) * | 1990-09-26 | 1990-11-07 | Beecham Group Plc | Novel compounds |
| DE4129603A1 (de) * | 1991-09-06 | 1993-03-11 | Thomae Gmbh Dr K | Kondensierte 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| GB9210839D0 (en) * | 1992-05-21 | 1992-07-08 | Smithkline Beecham Plc | Novel compounds |
| GB9312853D0 (en) | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
| US5591776A (en) | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| US5922751A (en) | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| AU4527896A (en) | 1994-12-13 | 1996-07-03 | Euro-Celtique S.A. | Aryl thioxanthines |
| ATE247655T1 (de) | 1994-12-13 | 2003-09-15 | Euro Celtique Sa | Dreifachsubstituierte thioxanthine |
| US6166041A (en) | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
| US6075016A (en) | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| US5864037A (en) | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
| US6821978B2 (en) | 2000-09-19 | 2004-11-23 | Schering Corporation | Xanthine phosphodiesterase V inhibitors |
| MXPA04001891A (es) | 2001-08-28 | 2004-06-15 | Schering Corp | Inhibidores policiclicos de guanina fosfodiesterasa v. |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US20100120694A1 (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CN108676076A (zh) | 2011-03-01 | 2018-10-19 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| RS65632B1 (sr) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Ltd | Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe |
| WO2015021358A2 (en) | 2013-08-09 | 2015-02-12 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1024968B (de) * | 1956-03-31 | 1958-02-27 | Asal Fabrik Biolog Und Pharmaz | Verfahren zur Herstellung von 7-Ketonyl-8-amino-theophyllinen |
| AT212847B (de) * | 1959-08-13 | 1961-01-10 | Hans Dr Med Voigt | Verfahren zur Herstellung des neuen Coffeino-(8)-(β-Phenyl-isopropyl)-amin |
| FR2157727A1 (en) * | 1971-10-29 | 1973-06-08 | Brun Lab Sa Le | !,#dimethyl-8-aminopurines - with analgesicantitussive and other theophylline-like activities |
| US4558051A (en) * | 1983-10-11 | 1985-12-10 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same |
| DE3400951A1 (de) * | 1984-01-13 | 1985-07-18 | Robert Bosch Gmbh, 7000 Stuttgart | Verfahren und vorrichtung zur drehzahlregelung bei einer brennkraftmaschine |
| HU197746B (en) * | 1985-09-05 | 1989-05-29 | Sandoz Ag | Process for producing xantin derivatives and pharmaceutical compositions containing them |
-
1987
- 1987-08-25 EP EP87810481A patent/EP0258191B1/en not_active Expired - Lifetime
- 1987-08-25 ES ES198787810481T patent/ES2033922T3/es not_active Expired - Lifetime
- 1987-08-25 DE DE8787810481T patent/DE3779374D1/de not_active Expired - Lifetime
- 1987-08-26 FI FI873704A patent/FI87356C/fi not_active IP Right Cessation
- 1987-08-26 PT PT85594A patent/PT85594B/pt not_active IP Right Cessation
- 1987-08-26 AU AU77445/87A patent/AU600021B2/en not_active Ceased
- 1987-08-26 IL IL83659A patent/IL83659A/xx not_active IP Right Cessation
- 1987-08-26 NZ NZ221571A patent/NZ221571A/en unknown
- 1987-08-26 CA CA000545408A patent/CA1289954C/en not_active Expired - Lifetime
- 1987-08-27 MY MYPI87001462A patent/MY101830A/en unknown
- 1987-08-27 HU HU873781A patent/HU199840B/hu not_active IP Right Cessation
- 1987-08-27 DK DK448787A patent/DK169337B1/da not_active IP Right Cessation
- 1987-08-27 PH PH35741A patent/PH24761A/en unknown
- 1987-08-27 IE IE229687A patent/IE60512B1/en not_active IP Right Cessation
- 1987-08-27 KR KR870009453A patent/KR880002870A/ko not_active Application Discontinuation
- 1987-08-27 JP JP62214119A patent/JPH0631236B2/ja not_active Expired - Lifetime
-
1992
- 1992-05-28 GR GR920401069T patent/GR3004747T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL83659A0 (en) | 1988-01-31 |
| FI87356B (fi) | 1992-09-15 |
| IE872296L (en) | 1988-02-28 |
| DE3779374D1 (en) | 1992-07-02 |
| DK448787A (da) | 1988-02-29 |
| CA1289954C (en) | 1991-10-01 |
| KR880002870A (ko) | 1988-05-12 |
| JPH0631236B2 (ja) | 1994-04-27 |
| NZ221571A (en) | 1990-11-27 |
| AU600021B2 (en) | 1990-08-02 |
| ES2033922T3 (es) | 1993-04-01 |
| IL83659A (en) | 1991-06-10 |
| EP0258191A1 (en) | 1988-03-02 |
| MY101830A (en) | 1992-01-31 |
| FI873704A (fi) | 1988-02-29 |
| EP0258191B1 (en) | 1992-05-27 |
| DK169337B1 (da) | 1994-10-10 |
| FI873704A0 (fi) | 1987-08-26 |
| HU199840B (en) | 1990-03-28 |
| GR3004747T3 (es) | 1993-04-28 |
| PT85594A (en) | 1987-09-01 |
| DK448787D0 (da) | 1987-08-27 |
| PT85594B (pt) | 1990-05-31 |
| HUT47111A (en) | 1989-01-30 |
| FI87356C (fi) | 1992-12-28 |
| JPS6363679A (ja) | 1988-03-22 |
| AU7744587A (en) | 1988-03-03 |
| IE60512B1 (en) | 1994-07-27 |
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