PH23736A - Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs - Google Patents

Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs

Info

Publication number
PH23736A
PH23736A PH34246A PH34246A PH23736A PH 23736 A PH23736 A PH 23736A PH 34246 A PH34246 A PH 34246A PH 34246 A PH34246 A PH 34246A PH 23736 A PH23736 A PH 23736A
Authority
PH
Philippines
Prior art keywords
parenteral
oral administration
water soluble
emulsion compositions
hydrophobic drugs
Prior art date
Application number
PH34246A
Other languages
English (en)
Inventor
Narendra Raghunathi Desai
Madurai Ganesan
Eugene Albert Carpenter
Edward Charles Shinal
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PH23736A publication Critical patent/PH23736A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PH34246A 1985-09-16 1986-09-11 Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs PH23736A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/776,306 US4784845A (en) 1985-09-16 1985-09-16 Emulsion compostions for the parenteral administration of sparingly water soluble ionizable hydrophobic drugs

Publications (1)

Publication Number Publication Date
PH23736A true PH23736A (en) 1989-11-03

Family

ID=25107019

Family Applications (1)

Application Number Title Priority Date Filing Date
PH34246A PH23736A (en) 1985-09-16 1986-09-11 Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs

Country Status (18)

Country Link
US (1) US4784845A (de)
EP (1) EP0215313B1 (de)
JP (1) JPS6267018A (de)
KR (1) KR890004684B1 (de)
AR (1) AR242716A1 (de)
AT (1) ATE78683T1 (de)
AU (1) AU591705B2 (de)
CA (1) CA1272447A (de)
DE (1) DE3686221T2 (de)
DK (1) DK165730C (de)
ES (1) ES2002750A6 (de)
FI (1) FI863728A (de)
GR (1) GR862354B (de)
HU (1) HU199282B (de)
NO (1) NO863670L (de)
NZ (1) NZ217484A (de)
PH (1) PH23736A (de)
ZA (1) ZA867009B (de)

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US5004593A (en) * 1989-04-17 1991-04-02 Mayo Foundation For Medical Education And Research Hexamethylmelamine formulation exhibiting reduced neurotoxicity
JPH0832638B2 (ja) * 1989-05-25 1996-03-29 カイロン コーポレイション サブミクロン油滴乳剤を含んで成るアジュバント製剤
GB8919172D0 (en) * 1989-08-23 1989-10-04 Univ Nottingham Useful composition
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US5534502A (en) * 1990-11-06 1996-07-09 Nippon Shinyaku Co. Ltd. Process for producing fat emulsion
DE4124252A1 (de) * 1991-07-22 1993-01-28 Knoll Ag Verfahren zur herstellung einer sterilfiltrierbaren wirkstoffloesung
IL103275A0 (en) * 1991-10-01 1993-02-21 Lilly Co Eli Injectable extended release formulations and methods
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JPH06245700A (ja) * 1993-02-23 1994-09-06 Snow Brand Milk Prod Co Ltd 消化吸収性を低減した油脂組成物
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MY112798A (en) * 1994-02-04 2001-09-29 Karlshamns Lipidteknik Ab Oil-in-water emulsions
EP0746318A1 (de) * 1994-02-25 1996-12-11 Takeda Chemical Industries, Ltd. Injizierbare emulsionen enthaltend fungizide triazolderivate
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
CA2185803C (en) * 1994-03-18 2006-07-11 Edward M. Rudnic Emulsified drug delivery systems
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US5616342A (en) * 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
US5824638A (en) * 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
WO1997011709A1 (en) * 1995-09-25 1997-04-03 Ashmont Holdings Limited Anthelmintic macrocyclic lactone compositions
EP0928136B1 (de) 1996-06-05 2003-10-22 Ashmont Holdings Limited Injizierbare zusammensetzungen
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US6054421A (en) * 1997-09-23 2000-04-25 Scimed Life Systems, Inc. Medical emulsion lubricant
US6281175B1 (en) 1997-09-23 2001-08-28 Scimed Life Systems, Inc. Medical emulsion for lubrication and delivery of drugs
AU752552C (en) * 1997-09-30 2003-09-11 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
US6036946A (en) * 1997-12-24 2000-03-14 Shaklee Corporation Methods for protecting skin from damaging effects of ultraviolet light
WO1999043301A1 (en) * 1998-02-24 1999-09-02 The Board Of Trustees Of The University Of Illinois Lipid emulsions in the treatment of systemic poisoning
US7030155B2 (en) * 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US6146664A (en) * 1998-07-10 2000-11-14 Shaklee Corporation Stable topical ascorbic acid compositions
US6682758B1 (en) 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system
US6777450B1 (en) * 2000-05-26 2004-08-17 Color Access, Inc. Water-thin emulsions with low emulsifier levels
IL162213A0 (en) * 2001-12-03 2005-11-20 Novacea Inc Pharmaceutical compositions containing active vitamin d compounds
AU2002353118A1 (en) * 2001-12-11 2003-07-24 Dor Biopharma, Inc. Lipid particles and suspensions and uses thereof
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040062779A1 (en) * 2002-09-26 2004-04-01 Jerry Whittemore Dermatologic composition using ultra-fine/micronized 1-ascorbic acid and other antioxidant ingredients in a stabilized anhydrous vehicle
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
US20050186230A1 (en) * 2004-01-23 2005-08-25 Sd Pharmaceuticals, Inc. Elemene compositions containing liquid oil
EP1838716B1 (de) 2005-01-05 2011-06-01 Eli Lilly And Company Olanzapinpamoat-dihydrat
KR101327649B1 (ko) 2005-03-31 2013-11-12 산토리 홀딩스 가부시키가이샤 리그난류 화합물 함유 수중 유적형 에멀션 및 그것을함유하는 조성물
JP2009515990A (ja) * 2005-11-17 2009-04-16 バイオアバイラビリティ，インク． 生体適合性潜在的乳化剤
EP2070532B1 (de) * 2006-10-04 2013-07-24 Suntory Holdings Limited Ö/w/ö emulsion mit einer lignan-verbindung und zusammensetzung damit
WO2009042114A2 (en) 2007-09-21 2009-04-02 The Johns Hopkins University Phenazine derivatives and uses thereof
WO2010008891A2 (en) * 2008-06-24 2010-01-21 Merial Limited Anthelminthic formulations
EP3024457A4 (de) 2013-07-26 2017-06-28 Update Pharma Inc. Zusammensetzungen zur verbesserung des therapeutischen nutzens von bisantren
CN105764491A (zh) 2013-12-09 2016-07-13 度瑞公司 药物活性剂复合物、聚合物复合物，以及包括其的组合物和方法
US11141398B2 (en) 2017-01-08 2021-10-12 The United States Government As Represented By The Department Of Veterans Affairs Methods for decreasing injuries associated with intraoperative hypotension
WO2019055370A1 (en) * 2017-09-12 2019-03-21 Academic Pharmaceuticals, Inc. METOLAZONE EMULSION FORMULATION
US20210401775A1 (en) * 2018-11-02 2021-12-30 Amaterasu Lifesciences Llp A liquid injectable composition

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US3996934A (en) * 1971-08-09 1976-12-14 Alza Corporation Medical bandage
FR2313078A1 (fr) * 1975-02-07 1976-12-31 Anvar Composition a base d'huile vegetale metabolisable et d'eau, utilisable notamment pour la constitution de preparations adjuvantes, ces preparations adjuvantes et leur procede d'obtention
DE2526938C2 (de) * 1975-02-14 1982-04-22 F. Hoffmann-La Roche & Co. AG, 4002 Basel Vitaminpräparate
US3991206A (en) * 1976-01-15 1976-11-09 American Cyanamid Company Alleviation of eye inflammation by topical application of p-biphenylacetic acid
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
JPS5822085B2 (ja) * 1977-07-19 1983-05-06 株式会社ミドリ十字 静注用ガンマ・グロブリン製剤
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US4340054A (en) * 1980-12-29 1982-07-20 Alza Corporation Dispenser for delivering fluids and solids
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US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs

Also Published As

Publication number Publication date
ES2002750A6 (es) 1988-10-01
EP0215313A2 (de) 1987-03-25
AR242716A1 (es) 1993-05-31
DK165730B (da) 1993-01-11
DE3686221D1 (de) 1992-09-03
EP0215313A3 (en) 1987-09-09
KR870002835A (ko) 1987-04-13
FI863728A0 (fi) 1986-09-15
EP0215313B1 (de) 1992-07-29
DK438286D0 (da) 1986-09-12
AU6269686A (en) 1987-03-19
DK438286A (da) 1987-03-17
AU591705B2 (en) 1989-12-14
ATE78683T1 (de) 1992-08-15
KR890004684B1 (ko) 1989-11-25
HUT43947A (en) 1988-01-28
FI863728A (fi) 1987-03-17
DK165730C (da) 1993-06-07
NO863670D0 (no) 1986-09-15
GR862354B (en) 1987-01-19
ZA867009B (en) 1987-07-29
CA1272447A (en) 1990-08-07
JPS6267018A (ja) 1987-03-26
NO863670L (no) 1987-03-17
DE3686221T2 (de) 1993-02-25
US4784845A (en) 1988-11-15
HU199282B (en) 1990-02-28
NZ217484A (en) 1990-04-26

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