PH23134A - 3-condensed imidazolium cephem compounds - Google Patents

3-condensed imidazolium cephem compounds

Info

Publication number
PH23134A
PH23134A PH32153A PH32153A PH23134A PH 23134 A PH23134 A PH 23134A PH 32153 A PH32153 A PH 32153A PH 32153 A PH32153 A PH 32153A PH 23134 A PH23134 A PH 23134A
Authority
PH
Philippines
Prior art keywords
cephem compounds
imidazolium
condensed
condensed imidazolium
cephem
Prior art date
Application number
PH32153A
Other languages
English (en)
Inventor
Akio Miyake
Masahiro Kondo
Masahiko Fujino
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1984/000212 external-priority patent/WO1985004879A1/ja
Priority claimed from PCT/JP1984/000270 external-priority patent/WO1985005620A1/ja
Priority claimed from PCT/JP1985/000102 external-priority patent/WO1986005184A1/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of PH23134A publication Critical patent/PH23134A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/081,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D505/00Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
PH32153A 1984-04-23 1985-04-18 3-condensed imidazolium cephem compounds PH23134A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/JP1984/000212 WO1985004879A1 (fr) 1984-04-23 1984-04-23 Nouveaux composes de cephem
PCT/JP1984/000270 WO1985005620A1 (en) 1984-05-25 1984-05-25 Cephem compounds
PCT/JP1985/000102 WO1986005184A1 (en) 1985-03-01 1985-03-01 Antibacterial compound

Publications (1)

Publication Number Publication Date
PH23134A true PH23134A (en) 1989-05-11

Family

ID=27304399

Family Applications (1)

Application Number Title Priority Date Filing Date
PH32153A PH23134A (en) 1984-04-23 1985-04-18 3-condensed imidazolium cephem compounds

Country Status (13)

Country Link
EP (1) EP0160252B1 (de)
JP (1) JPH07103130B2 (de)
KR (2) KR920008945B1 (de)
AU (1) AU580995B2 (de)
CA (1) CA1283096C (de)
DE (2) DE3586547D1 (de)
ES (4) ES8606362A1 (de)
FI (1) FI851592L (de)
GR (1) GR850965B (de)
NO (2) NO165842C (de)
NZ (1) NZ211858A (de)
PH (1) PH23134A (de)
PT (1) PT80328B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH22107A (en) * 1984-06-07 1988-06-01 Takeda Chemical Industries Ltd 3-pyrazolo(1,5-a)pyrdinium cephem compounds
ATE89826T1 (de) * 1985-03-01 1993-06-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
EP0203271B1 (de) * 1985-03-01 1993-05-26 Takeda Chemical Industries, Ltd. Antibakterielle Verbindungen, ihre Herstellung und Verwendung
US4921851A (en) * 1986-06-09 1990-05-01 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
JP2519054B2 (ja) * 1986-06-09 1996-07-31 武田薬品工業株式会社 新規セフェム化合物
DE3707019A1 (de) * 1987-03-05 1988-09-15 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
AU615966B2 (en) * 1987-12-04 1991-10-17 Takeda Chemical Industries Ltd. Crystals of cephem hydrochloride
US4933334A (en) * 1987-12-04 1990-06-12 Takeda Chemical Industries, Ltd. Antibiotic composition
ATE117690T1 (de) * 1990-03-01 1995-02-15 Takeda Chemical Industries Ltd Imidazopyridazine, ihre herstellung und verwendung.
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
DE602004024297D1 (de) * 2003-04-30 2010-01-07 Trine Pharmaceuticals Inc Carbacephem beta-lactam-antibiotika
PT2960244T (pt) 2008-10-31 2016-11-02 Shionogi & Co Cefalosporina contendo grupo catecol
EP2557082A4 (de) 2010-04-05 2013-08-28 Shionogi & Co Cephemverbindung mit einer catecholgruppe
TWI547496B (zh) 2011-10-04 2016-09-01 葛蘭素集團公司 抗菌化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165430A (en) * 1976-03-19 1979-08-21 Glaxo Laboratories Limited Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group
EP0062321B1 (de) * 1981-04-03 1989-03-01 Fujisawa Pharmaceutical Co., Ltd. Cephalosporinderivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Präparate und ihre Ausgangsprodukte
DE3336757A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPH07103130B2 (ja) 1995-11-08
KR850007427A (ko) 1985-12-04
DE3586547A1 (de) 1993-02-04
ES553666A0 (es) 1987-06-16
PT80328B (en) 1987-02-16
ES542447A0 (es) 1986-04-01
PT80328A (en) 1985-05-01
EP0160252B1 (de) 1992-08-26
ES557129A0 (es) 1987-12-01
FI851592A0 (fi) 1985-04-22
KR920008945B1 (ko) 1992-10-12
ES8606362A1 (es) 1986-04-01
ES8800950A1 (es) 1987-12-01
NZ211858A (en) 1988-08-30
KR920008953B1 (ko) 1992-10-12
ES8706692A1 (es) 1987-06-16
GR850965B (de) 1985-11-25
DE3586547T2 (de) 1993-04-15
NO167293C (no) 1991-10-23
JPS60231684A (ja) 1985-11-18
DE3586547D1 (de) 1993-02-04
NO854730L (no) 1985-10-24
NO165842C (no) 1991-04-17
NO165842B (no) 1991-01-07
FI851592L (fi) 1985-10-24
EP0160252A3 (en) 1987-01-14
AU580995B2 (en) 1989-02-09
NO167293B (no) 1991-07-15
ES8707245A1 (es) 1987-07-16
CA1283096C (en) 1991-04-16
ES549180A0 (es) 1987-07-16
AU4170085A (en) 1985-10-31
NO851538L (no) 1985-10-24
EP0160252A2 (de) 1985-11-06

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