PH22862A - Novel quinoline derivatives and method of use thereof - Google Patents

Novel quinoline derivatives and method of use thereof

Info

Publication number
PH22862A
PH22862A PH34426A PH34426A PH22862A PH 22862 A PH22862 A PH 22862A PH 34426 A PH34426 A PH 34426A PH 34426 A PH34426 A PH 34426A PH 22862 A PH22862 A PH 22862A
Authority
PH
Philippines
Prior art keywords
quinoline derivatives
novel quinoline
novel
derivatives
quinoline
Prior art date
Application number
PH34426A
Other languages
English (en)
Inventor
Jun-Ichi Matsumoto
Teruyuki Miyamoto
Hiroshi Egawa
Shinichi Nakamura
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of PH22862A publication Critical patent/PH22862A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH34426A 1985-10-29 1986-10-29 Novel quinoline derivatives and method of use thereof PH22862A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24225785 1985-10-29
JP28532385 1985-12-17
JP3262786 1986-02-17

Publications (1)

Publication Number Publication Date
PH22862A true PH22862A (en) 1989-01-19

Family

ID=27287785

Family Applications (1)

Application Number Title Priority Date Filing Date
PH34426A PH22862A (en) 1985-10-29 1986-10-29 Novel quinoline derivatives and method of use thereof

Country Status (26)

Country Link
US (1) US4795751A (de)
EP (2) EP0375658B1 (de)
JP (2) JPS62277362A (de)
KR (1) KR910006806B1 (de)
CN (1) CN1009930B (de)
AR (3) AR242031A1 (de)
AT (2) ATE66210T1 (de)
AU (1) AU594983B2 (de)
CA (1) CA1340402C (de)
DE (3) DE10075028I2 (de)
DK (2) DK170593B1 (de)
ES (2) ES2029786T3 (de)
FI (1) FI87457C (de)
GE (1) GEP19960467B (de)
GR (1) GR3002475T3 (de)
HU (1) HU200452B (de)
IL (1) IL80404A (de)
LU (2) LU88596I2 (de)
MY (1) MY100574A (de)
NL (2) NL970020I2 (de)
NO (1) NO170726C (de)
NZ (1) NZ218089A (de)
PH (1) PH22862A (de)
PT (1) PT83643B (de)
SU (2) SU1598873A3 (de)
YU (3) YU46414B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
EP0242789A3 (de) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Chinolinderivate und Verfahren zu ihrer Herstellung
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4780468A (en) * 1987-08-07 1988-10-25 Warner-Lambert Company 8-trifluoromethyl quinolones as antibacterial agents
IL88003A (en) * 1987-10-16 1992-11-15 Dainippon Pharmaceutical Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
US5164392A (en) * 1987-10-16 1992-11-17 Dainippon Pharmaceutical Co., Ltd. Quinoline derivatives and antibacterial agent containing them
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
JP2709604B2 (ja) * 1988-06-29 1998-02-04 大日本製薬株式会社 マイコプラズマ汚染の防止または除去
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
FR2655545B1 (fr) 1989-12-11 1994-06-10 Rhone Poulenc Sante Nouvelle application therapeutique des derives des fluoroquinolones.
DE4019023A1 (de) * 1990-06-14 1991-12-19 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
JP2613139B2 (ja) * 1990-07-19 1997-05-21 エスエス製薬 株式会社 キノロンカルボン酸誘導体
US5342846A (en) * 1990-12-05 1994-08-30 Synphar Laboratories, Inc. 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
FR2681863B1 (fr) * 1991-09-27 1995-02-03 Rhone Dpc Europ Solution de sparfloxacine sa preparation et sel la constituant.
US5430028A (en) * 1992-05-26 1995-07-04 Ss Pharmaceutical Co., Ltd. 5-aminoquinolone carboxylic acid derivative and antibacterial agent containing the same as active ingredient
WO1993025545A1 (en) * 1992-06-09 1993-12-23 Korea Research Institute Of Chemical Technology Novel quinoline derivatives and processes for preparing the same
US5290794A (en) * 1992-10-27 1994-03-01 Warner Lambert Co. Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
CN1038326C (zh) * 1993-07-20 1998-05-13 爱斯制药株式会社 5-氨基喹诺酮羧酸衍生物及其含有该衍生物作为活性成分的抗菌剂
US5532239A (en) * 1993-08-02 1996-07-02 Assistance Publique - Hopitaux De Paris Therapeutic application of fluoroquinolone derivatives
EP1135132A2 (de) 1998-12-04 2001-09-26 Influx, Inc. Inhibitoren des multidrogentransportes
EP1161956A4 (de) 1999-03-17 2005-03-16 Daiichi Seiyaku Co Medikamentenzusammensetzung
CN1091103C (zh) * 1999-04-02 2002-09-18 中国科学院上海药物研究所 一类喹诺酮类化合物及它的制备和其用途
US6957105B2 (en) * 2002-03-26 2005-10-18 Cardiac Pacemakers, Inc. Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals
KR100519158B1 (ko) * 2002-12-21 2005-10-06 주식회사유한양행 퀴놀론 카르복실레이트 유도체의 제조방법
US20070196398A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone fatty acid salt compositions
US20070197548A1 (en) 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
US7973022B2 (en) 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
ES2962526T3 (es) 2017-06-22 2024-03-19 Cipla Ltd Secretagogos PAR-4 para el tratamiento del cáncer
CN112939860B (zh) * 2019-11-11 2022-11-11 山东畜牧兽医职业学院 一种治疗耐药性革兰阴阳性菌的化合物及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753993A (en) * 1971-05-17 1973-08-21 Sterling Drug Inc 1,4-dihydro-4-oxo-7-pyridyl-3-quinoline-carboxylic acid derivatives
DE3033157A1 (de) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS58174367A (ja) 1982-04-07 1983-10-13 Tanabe Seiyaku Co Ltd キノリン誘導体及びその製法
DE3248507A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen Mikrobizide mittel auf chinoloncarbonsaeure basis
DE3248506A1 (de) 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(alkyl-1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3306771A1 (de) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
JPS60169475A (ja) * 1984-02-14 1985-09-02 Dai Ichi Seiyaku Co Ltd キノリン誘導体
DE3574380D1 (en) 1984-02-17 1989-12-28 Daiichi Seiyaku Co 1,8-naphthyridine derivatives
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
ZA852369B (en) 1984-04-26 1985-12-24 Abbott Lab Quinoline antibacterial compounds
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS6110574A (ja) * 1984-06-25 1986-01-18 Hokuriku Seiyaku Co Ltd 6−フルオロ−1,4−ジヒドロ−4−オキソ−7−置換ピペラジニルキノリン−3−カルボン酸誘導体
IE58742B1 (en) 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPS6191183A (ja) * 1984-10-11 1986-05-09 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
EP0181521A1 (de) * 1984-10-19 1986-05-21 Otsuka Pharmaceutical Co., Ltd. 1-Substituierte Phenyl-4-oxochinolin-3-carbonsäure-Verbindungen
US4636506A (en) * 1984-12-06 1987-01-13 Pfizer, Inc. 7-heterocyclic-1,4-dihydroquinolones
DE3576335D1 (de) * 1984-12-14 1990-04-12 Daiichi Seiyaku Co Chinolincarbonsaeure-derivate.
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
JPS6259263A (ja) * 1985-09-10 1987-03-14 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
EP0230053A3 (de) * 1986-01-17 1988-03-30 American Cyanamid Company 7-(Substituierte)Piperazinyl-1-äthyl-6-fluor-1,4-dihydro-4-oxo-3-chinolinkarbonsäure
EP0242789A3 (de) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Chinolinderivate und Verfahren zu ihrer Herstellung
GB8612137D0 (en) * 1986-05-19 1986-06-25 Fujisawa Pharmaceutical Co Quinolone compounds

Also Published As

Publication number Publication date
DE3650018T2 (de) 1995-01-05
YU137191A (sh) 1994-01-20
FI87457C (fi) 1993-01-11
CA1340402C (en) 1999-02-23
DK514586D0 (da) 1986-10-28
NO170726C (no) 1992-11-25
DE10075028I1 (de) 2000-12-14
GR3002475T3 (en) 1992-12-30
DE3680859D1 (de) 1991-09-19
AR243520A1 (es) 1993-08-31
DK25992A (da) 1992-02-28
EP0221463A2 (de) 1987-05-13
DE3650018D1 (de) 1994-09-08
PT83643B (pt) 1988-10-14
DK170774B1 (da) 1996-01-15
JPH0714918B2 (ja) 1995-02-22
FI864299A0 (fi) 1986-10-23
NL300014I2 (nl) 2001-02-01
AR243178A1 (es) 1993-07-30
HU200452B (en) 1990-06-28
GEP19960467B (en) 1996-05-27
HUT43839A (en) 1987-12-28
JPH0541633B2 (de) 1993-06-24
CN1009930B (zh) 1990-10-10
YU183586A (en) 1988-04-30
NO864247L (no) 1987-04-30
ATE66210T1 (de) 1991-08-15
KR910006806B1 (ko) 1991-09-02
AR242031A1 (es) 1993-02-26
PT83643A (en) 1986-11-01
EP0221463B1 (de) 1991-08-14
EP0221463A3 (en) 1987-12-02
DE10075028I2 (de) 2004-01-29
LU88596I2 (fr) 1995-07-10
NO864247D0 (no) 1986-10-23
IL80404A0 (en) 1987-01-30
NZ218089A (en) 1989-03-29
CN86107491A (zh) 1987-04-29
IL80404A (en) 1990-06-10
ATE109472T1 (de) 1994-08-15
JPH0543551A (ja) 1993-02-23
FI87457B (fi) 1992-09-30
DK25992D0 (da) 1992-02-28
ES2057197T3 (es) 1994-10-16
ES2029786T3 (es) 1992-10-01
DK514586A (da) 1987-04-30
US4795751A (en) 1989-01-03
LU90621I2 (fr) 2000-10-09
DK170593B1 (da) 1995-11-06
NO170726B (no) 1992-08-17
NL970020I2 (nl) 1998-01-05
FI864299A (fi) 1987-04-30
NL970020I1 (nl) 1997-08-01
EP0375658B1 (de) 1994-08-03
NL300014I1 (nl) 2000-10-02
JPS62277362A (ja) 1987-12-02
AU594983B2 (en) 1990-03-22
YU46414B (sh) 1993-10-20
MY100574A (en) 1990-12-15
AU6427786A (en) 1987-04-30
SU1635898A3 (ru) 1991-03-15
KR870004019A (ko) 1987-05-06
EP0375658A1 (de) 1990-06-27
YU137291A (sh) 1994-01-20
SU1598873A3 (ru) 1990-10-07

Similar Documents

Publication Publication Date Title
PH22862A (en) Novel quinoline derivatives and method of use thereof
PH23495A (en) Phenoxyalkylaminopyrimidine derivatives and the composition and method of use thereof
PL260806A1 (en) Method of obtaining novel derivatives of avermectine
PH22141A (en) N-aralkyl piperidinemethanol derivatives and method of use thereof
PH21588A (en) Pleuromutilin derivatives and method of use thereof
ZA869139B (en) Sulfomethylamide-containing polymers and method of preparing same
PL262599A1 (en) Method of obtaining derivatives of quinolone
PL261011A1 (en) Novel method of obtaining sphingozine derivatives
PL260921A1 (en) Method of obtaining novel derivatives of n-4-pyridylamide
EP0221677A3 (en) P-aminophenols, derivatives thereof and method of use
GB2186192B (en) Catheter and method of making same
GR860744B (en) Tampons and method of making
PL261196A1 (en) Method of obtaining derivatives of methylenedihydroxyphenathrene and stilbene
PH22427A (en) Eburnamenine derivatives and method of use thereof
GB2175006B (en) Method and apparatus of brewing
AR242570A1 (es) Procedimiento para preparar derivados de acido 4,4'-metilen-bis-(3-hidroxi)-2-naftoico y obtencion de preparados bactericidas orales en base a los mismos.
CS783386A3 (en) Novel derivatives of quinoline, their esters and salts
PL266025A1 (en) Method of obtaining novel quinoline derivatives
BG40405A1 (en) Method for manufacture of lysergol and its derivatives
ZA868094B (en) Novel quinoline derivatives and processes for preparation thereof
PL265496A1 (en) Method of obtaining novel derivatives of trihalogenimidazole
BG40218A1 (en) 2- (cycloalkyloxymethyl) morpholenes and method of preparation
RO92738B1 (ro) Metoda de analgezie rapida
BG40732A1 (en) Derivatives of 4- (2- arylvinyl)- 3- acetyl- 2h- 1- benzopyran- 2- on and method for their preparing
BG40731A1 (en) Derivatives of 3- cynamoyl- 2h- 1- benzopyran- 2- on and method for their preparing