PH22007A - A new process for the synthesis of pyridoimidazorifaycins - Google Patents

A new process for the synthesis of pyridoimidazorifaycins

Info

Publication number
PH22007A
PH22007A PH32186A PH32186A PH22007A PH 22007 A PH22007 A PH 22007A PH 32186 A PH32186 A PH 32186A PH 32186 A PH32186 A PH 32186A PH 22007 A PH22007 A PH 22007A
Authority
PH
Philippines
Prior art keywords
pyridoimidazorifaycins
synthesis
new process
new
Prior art date
Application number
PH32186A
Other languages
English (en)
Inventor
Cannata Veincenzo
Tamagnone Gian Franco
Piani Silvano
Marchi Egidio
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of PH22007A publication Critical patent/PH22007A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH32186A 1984-05-15 1985-04-25 A new process for the synthesis of pyridoimidazorifaycins PH22007A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03463/84A IT1199374B (it) 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine

Publications (1)

Publication Number Publication Date
PH22007A true PH22007A (en) 1988-05-02

Family

ID=11107845

Family Applications (1)

Application Number Title Priority Date Filing Date
PH32186A PH22007A (en) 1984-05-15 1985-04-25 A new process for the synthesis of pyridoimidazorifaycins

Country Status (18)

Country Link
US (1) US4557866A (da)
EP (1) EP0161534B1 (da)
JP (1) JPS60252483A (da)
AR (1) AR241913A1 (da)
AT (1) ATE46512T1 (da)
AU (1) AU568934B2 (da)
CA (1) CA1215708A (da)
DE (1) DE3573120D1 (da)
DK (1) DK162647C (da)
ES (1) ES543115A0 (da)
FI (1) FI81101C (da)
GR (1) GR851144B (da)
IE (1) IE58392B1 (da)
IT (1) IT1199374B (da)
NO (1) NO164242C (da)
PH (1) PH22007A (da)
PT (1) PT80446B (da)
ZA (1) ZA852971B (da)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US7078399B2 (en) * 2001-12-13 2006-07-18 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US7923553B2 (en) 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US7902206B2 (en) 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US7906542B2 (en) 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
DK1698630T3 (da) * 2005-03-03 2014-12-08 Alfa Wassermann Spa Nye polymorfe former af rifaximin, fremgangsmåde for deres fremstilling og anvendelse deraf i de medicinske præparater
ITBO20050123A1 (it) * 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
ES2747259T3 (es) 2006-03-09 2020-03-10 Salix Pharmaceuticals Inc Preparación anti-disfunción rectal de rifaximina
CA2659874C (en) 2006-08-02 2016-10-11 Salix Pharmaceuticals, Inc. Methods for the treatment of radiation proctosigmoiditis
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
EP2069363B1 (en) * 2006-09-22 2013-03-20 Cipla Ltd. Rifaximin in an amorphous form
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
US7709634B2 (en) 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
CN102015725B (zh) 2008-02-25 2014-10-22 萨利克斯药品有限公司 利福昔明的多种形式及其用途
PL2252148T3 (pl) 2008-02-26 2019-09-30 Salix Pharmaceuticals, Ltd. Sposoby leczenia zespołu jelita drażliwego
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
DK2294012T3 (da) 2008-05-07 2014-10-06 Salix Pharmaceuticals Ltd Administration af et tarmrensemiddel og et antibiotika til behandlingen af tarmsygdom
CN101585843B (zh) * 2008-05-21 2011-07-06 重庆赛诺生物药业股份有限公司 一种利福昔明的制备工艺
SI3628319T1 (sl) 2008-10-02 2024-04-30 Salix Pharmaceuticals, Ltd. Zdravljenje jetrne encefalopatije z rifaksiminom
US20110035232A1 (en) 2008-10-02 2011-02-10 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
US7928115B2 (en) 2008-10-02 2011-04-19 Salix Pharmaceuticals, Ltd. Methods of treating travelers diarrhea and hepatic encephalopathy
JP5756020B2 (ja) 2008-12-10 2015-07-29 シプラ・リミテッド リファキシミン複合体
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
NZ596851A (en) 2009-06-02 2013-10-25 Salix Pharmaceuticals Ltd Methods of treating hepatic encephalopathy
KR20120062897A (ko) 2009-09-13 2012-06-14 샐릭스 파마슈티컬스 리미티드 과민성 장 증후군(ｉｂｓ)의 치료방법
BR112012012316A2 (pt) 2009-11-23 2016-04-26 Cipla Ltd composição farmacêutica para administração retal tópica na forma de espuma, uso de uma composição farmacêutica, método para tratamento, prevenção ou alívio de um dustúrbio no reto, cólon, íleo terminal ou ânus, processo para fabricação de uma composição farmacêutica contendo rifaximina, uso de um silicone e dispensador para composição farmacêutica
WO2011080691A1 (en) 2009-12-28 2011-07-07 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
AU2011218129A1 (en) 2010-02-18 2012-08-23 Board Of Regents Of The University Of Texas System Methods for treating infection
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
WO2011156897A2 (en) * 2010-06-16 2011-12-22 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
CN103228662B (zh) 2010-07-12 2016-08-10 萨利克斯药品有限公司 利福昔明的制剂及其用途
US8759513B2 (en) 2010-09-13 2014-06-24 Sequent Scientific Limited Polymorphic form of rifaximin and process for its preparation
US8735419B2 (en) 2011-02-11 2014-05-27 Salix Pharmaceuticals, Ltd. Forms of rifaximin and uses thereof
CA2834829A1 (en) 2011-05-02 2012-11-08 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
WO2012155981A1 (en) 2011-05-19 2012-11-22 Friulchem Spa New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
AU2012332211B2 (en) 2011-11-02 2016-11-24 Salix Pharmaceuticals, Ltd. Methods for treating irritable bowel syndrome (IBS) and infections
US9359374B2 (en) 2012-06-13 2016-06-07 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
US20160038468A1 (en) 2013-03-15 2016-02-11 Alfa Wassermann S.P.A. Rifaximin for use in the treating of vaginal infections
EP2971062A2 (en) 2013-03-15 2016-01-20 ALFA WASSERMANN S.p.A. Method for diagnosing vaginal infections
JP6433980B2 (ja) 2013-04-12 2018-12-05 アルファシグマ ソシエタ ペル アチオニ Ｎｓａｉｄ投与並びに関連する組成物、方法及びシステム
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
ITMI20131307A1 (it) 2013-08-02 2015-02-02 A M S A Anonima Materie Sint & Affini S P A Processo per la preparazione di refaximina k
CN103509038B (zh) * 2013-09-30 2016-01-20 浙江思贤制药有限公司 一种新晶型利福昔明ζ及其制备方法
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
CA2947962C (en) 2014-05-04 2024-01-16 Salix Pharmaceuticals, Inc. Ibs microbiota and uses thereof
ES2742106T3 (es) 2014-05-12 2020-02-13 Alfasigma Spa Nueva forma de cristal solvatado de rifaximina, producción, composiciones y usos de la misma
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
WO2018064472A1 (en) 2016-09-30 2018-04-05 Salix Pharmaceuticals, Ltd. Solid dispersion forms of rifaximin
PL3645539T3 (pl) * 2017-06-26 2021-10-25 Biofer S.P.A. Pochodne pirydoimidazoryfamycyny jako środek przeciwbakteryjny

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1154655B (it) * 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Also Published As

Publication number Publication date
EP0161534A3 (en) 1987-03-04
PT80446A (en) 1985-06-01
DK162647B (da) 1991-11-25
NO851921L (no) 1985-11-18
EP0161534B1 (en) 1989-09-20
FI81101B (fi) 1990-05-31
DK214685D0 (da) 1985-05-14
AU4251585A (en) 1985-11-21
NO164242C (no) 1990-09-12
AU568934B2 (en) 1988-01-14
JPH0469634B2 (da) 1992-11-06
DE3573120D1 (en) 1989-10-26
ATE46512T1 (de) 1989-10-15
ZA852971B (en) 1985-12-24
IE851191L (en) 1985-11-15
NO164242B (no) 1990-06-05
IT8403463A0 (it) 1984-05-15
EP0161534A2 (en) 1985-11-21
FI851907A0 (fi) 1985-05-14
US4557866A (en) 1985-12-10
IT1199374B (it) 1988-12-30
PT80446B (pt) 1987-11-11
DK214685A (da) 1985-11-16
ES8603489A1 (es) 1986-01-01
CA1215708A (en) 1986-12-23
GR851144B (da) 1985-11-25
AR241913A1 (es) 1993-01-29
IE58392B1 (en) 1993-09-08
ES543115A0 (es) 1986-01-01
FI851907L (fi) 1985-11-16
DK162647C (da) 1992-04-13
JPS60252483A (ja) 1985-12-13
FI81101C (fi) 1990-09-10

Similar Documents

Publication Publication Date Title
PH22007A (en) A new process for the synthesis of pyridoimidazorifaycins
HUT38954A (en) Process for producing new peptid-aldehydes
PT79963A (en) Process for the preparation of asymetric diesthers
HUT38324A (en) Process for producing new 1-aryl-5h-2beta-beta-benzodiazepines
YU200985A (en) Process for producing acilated diketonic compounds
HUT39190A (en) Process for producing new compounds
HUT38339A (en) Process for producing dihydropyridine-carbonyl compounds
PT80322A (en) Process for urea synthesis
DE3480339D1 (en) A new process for the preparation of alpha-6-deoxy-tetracyclines
DE3571028D1 (en) A process for the preparation of p-isononanoyloxybenzenenesulphonate
DE3571603D1 (en) Process for the synthesis of 2-methoxy-6-bromo-naphthalene
IL76901A0 (en) Process for the resolution of a racemate
PT80447A (en) A new process for the synthesis of imidazo rifamycins
PT81198A (en) A new process for the synthesis of pyrido-imidazo-rifamycins
GB2178749B (en) A process for the manufacture of a solid urea-formaldehyde-resin
DE3570438D1 (en) A process for the preparation of bis-phosphineoxide compounds
DE3560592D1 (en) A process for the preparation of l-tryptophan
GB2161802B (en) Process for producing n-chlorosulfenyl compounds
PT79934B (en) Process for the manufacture of a carbazole derivative
HUT40807A (en) Process for producing new citostatic materials
DE3563742D1 (en) Process for the synthesis of aminonitropyridines
HUT37428A (en) Process for the production of new apovincaminol-derivatives
DE3568347D1 (en) Process for the production of chanoclavin
GB2149399B (en) A process for the preparation of 2-hydroxy-5-1-hydroxy-2-(4phenyl-2-bukyl)-amine-ethyl-benzamide
YU132785A (en) Process for silicophosphoaluminate synthesis