PH18297A - 1-phenyl-2(h,3h)endolone psychotherapeutic agents - Google Patents

1-phenyl-2(h,3h)endolone psychotherapeutic agents

Info

Publication number
PH18297A
PH18297A PH29565A PH29565A PH18297A PH 18297 A PH18297 A PH 18297A PH 29565 A PH29565 A PH 29565A PH 29565 A PH29565 A PH 29565A PH 18297 A PH18297 A PH 18297A
Authority
PH
Philippines
Prior art keywords
phenyl
indolones
treatment
endolone
psychotherapeutic agents
Prior art date
Application number
PH29565A
Other languages
English (en)
Inventor
Harry Ralph Howard Jr
Reinhard Sarges
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH18297A publication Critical patent/PH18297A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PH29565A 1982-09-20 1983-09-20 1-phenyl-2(h,3h)endolone psychotherapeutic agents PH18297A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/420,544 US4476307A (en) 1982-09-20 1982-09-20 Heteroylidene indolone compounds

Publications (1)

Publication Number Publication Date
PH18297A true PH18297A (en) 1985-05-24

Family

ID=23666904

Family Applications (1)

Application Number Title Priority Date Filing Date
PH29565A PH18297A (en) 1982-09-20 1983-09-20 1-phenyl-2(h,3h)endolone psychotherapeutic agents

Country Status (24)

Country Link
US (1) US4476307A (de)
EP (1) EP0104860B1 (de)
JP (1) JPS5976058A (de)
KR (1) KR860001270B1 (de)
AT (1) ATE25972T1 (de)
AU (1) AU543115B2 (de)
CA (1) CA1194871A (de)
DD (1) DD213211A5 (de)
DE (1) DE3370325D1 (de)
DK (1) DK157010C (de)
ES (3) ES8503328A1 (de)
FI (1) FI77446C (de)
GR (1) GR79732B (de)
HU (1) HU189747B (de)
IE (1) IE55923B1 (de)
IL (1) IL69758A (de)
NO (1) NO161557C (de)
NZ (1) NZ205638A (de)
PH (1) PH18297A (de)
PL (3) PL141370B1 (de)
PT (1) PT77360B (de)
SU (1) SU1272983A3 (de)
YU (4) YU189283A (de)
ZA (1) ZA836933B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879391A (en) * 1982-09-20 1989-11-07 Pfizer Inc. 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
HU217072B (hu) * 1989-01-10 1999-11-29 Pfizer Inc. 1-Heteroaril-oxindol-3-karboxamid-származékok, azok előállítása, és az azokat tartalmazó gyógyszerkészítmények
US5078756A (en) * 1990-01-12 1992-01-07 Major Thomas O Apparatus and method for purification and recovery of refrigerant
US5158969A (en) * 1991-08-21 1992-10-27 Neurosearch A/S Indole derivatives as potassium channel blockers
US5760250A (en) * 1991-11-05 1998-06-02 Zeneca Limited Process for the preparation of 3-(α-methoxy)methylenebenzofuranones and intermediates therefor
DE19949209A1 (de) * 1999-10-13 2001-04-19 Boehringer Ingelheim Pharma In 5-Stellung substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel
AU2002341881B2 (en) * 2001-09-27 2008-05-08 Allergan, Inc. 3-(arylamino)methylene-1, 3-dihydro-2h-indol-2-ones as kinase inhibitors
US20050101788A1 (en) * 2002-03-27 2005-05-12 Jacopo Zanon Method for manufacture of sertindole
FR2847813A1 (fr) * 2002-11-29 2004-06-04 Oreal Compositions cosmetiques photoprotectrices contenant des derives de 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one et utilisations
FR2847811B1 (fr) * 2002-11-29 2005-01-07 Oreal Composition filtrante contenant au moins un derive du dibenzoylmethane et au moins un derive de 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one;procede de photostabilisation
ES2524922T3 (es) 2005-05-10 2014-12-15 Intermune, Inc. Derivados de piridona para modular el sistema de proteína cinasa activada por estrés
EP2296653B1 (de) 2008-06-03 2016-01-27 Intermune, Inc. Verbindungen und verfahren zur behandlung von entzündungserkrankungen und fibrotischen erkrankungen
PL2380876T3 (pl) 2008-12-19 2015-02-27 Nippon Soda Co Pochodna 1-heterodienu i środek do zwalczania szkodników
US9012493B2 (en) 2009-11-12 2015-04-21 Nippon Soda Co., Ltd. 1-heterodiene derivative and pest control agent
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
US10233195B2 (en) 2014-04-02 2019-03-19 Intermune, Inc. Anti-fibrotic pyridinones

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3506683A (en) * 1963-10-07 1970-04-14 Upjohn Co 3-(2-pyrrolidinylidene)-3h-indoles
GB1237008A (en) * 1968-12-18 1971-06-30 Pfizer Ltd Novel indoline derivatives
US3723457A (en) * 1969-09-30 1973-03-27 Eisai Co Ltd Indoline-2-one derivatives and preparation thereof
GB1374414A (en) * 1972-06-12 1974-11-20 Sterling Drug Inc 1-acyl-3-amino-alkyl-indoles and their preparation
DE2557342A1 (de) * 1975-12-19 1977-06-30 Hoechst Ag Basisch substituierte indolderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
FI77446C (fi) 1989-03-10
PL141876B1 (en) 1987-09-30
ATE25972T1 (de) 1987-04-15
JPS6241711B2 (de) 1987-09-04
AU543115B2 (en) 1985-04-04
SU1272983A3 (ru) 1986-11-23
US4476307A (en) 1984-10-09
ES531908A0 (es) 1985-06-01
YU169386A (en) 1987-10-31
NZ205638A (en) 1986-12-05
PL250768A1 (en) 1985-07-02
IE832193L (en) 1984-03-20
IL69758A (en) 1986-12-31
EP0104860A1 (de) 1984-04-04
DK157010B (da) 1989-10-30
PT77360A (en) 1983-10-01
KR860001270B1 (ko) 1986-09-04
DD213211A5 (de) 1984-09-05
ES525737A0 (es) 1985-02-16
PL141609B1 (en) 1987-08-31
JPS5976058A (ja) 1984-04-28
DK157010C (da) 1990-03-26
YU169186A (en) 1987-10-31
FI833335A0 (fi) 1983-09-19
PL250769A1 (en) 1985-07-02
FI833335A (fi) 1984-03-21
DK425383A (da) 1984-05-03
IL69758A0 (en) 1983-12-30
ES8505951A1 (es) 1985-06-01
PT77360B (en) 1986-05-19
ZA836933B (en) 1985-05-29
YU189283A (en) 1987-10-31
AU1925283A (en) 1984-03-29
EP0104860B1 (de) 1987-03-18
DE3370325D1 (en) 1987-04-23
DK425383D0 (da) 1983-09-19
GR79732B (de) 1984-10-31
FI77446B (fi) 1988-11-30
ES8503328A1 (es) 1985-02-16
IE55923B1 (en) 1991-02-27
PL141370B1 (en) 1987-07-31
PL243826A1 (en) 1985-04-24
KR840006239A (ko) 1984-11-22
NO161557C (no) 1989-08-30
NO161557B (no) 1989-05-22
ES531907A0 (es) 1985-06-01
NO833367L (no) 1984-03-21
ES8505950A1 (es) 1985-06-01
HU189747B (en) 1986-07-28
YU169286A (en) 1987-10-31
CA1194871A (en) 1985-10-08

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