ES531908A0 - Un procedimiento para la preparacion de nuevas indolonas. - Google Patents
Un procedimiento para la preparacion de nuevas indolonas.Info
- Publication number
- ES531908A0 ES531908A0 ES531908A ES531908A ES531908A0 ES 531908 A0 ES531908 A0 ES 531908A0 ES 531908 A ES531908 A ES 531908A ES 531908 A ES531908 A ES 531908A ES 531908 A0 ES531908 A0 ES 531908A0
- Authority
- ES
- Spain
- Prior art keywords
- indolones
- phenyl
- treatment
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Dental Preparations (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/420,544 US4476307A (en) | 1982-09-20 | 1982-09-20 | Heteroylidene indolone compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES531908A0 true ES531908A0 (es) | 1985-06-01 |
| ES8505951A1 ES8505951A1 (es) | 1985-06-01 |
Family
ID=23666904
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES525737A Expired ES8503328A1 (es) | 1982-09-20 | 1983-09-19 | Un procedimiento para la preparacion de nuevas idolonas. |
| ES531907A Granted ES531907A0 (es) | 1982-09-20 | 1984-04-25 | Un procedimiento para la preparacion de nuevas indolonas. |
| ES531908A Expired ES8505951A1 (es) | 1982-09-20 | 1984-04-25 | Un procedimiento para la preparacion de nuevas indolonas. |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES525737A Expired ES8503328A1 (es) | 1982-09-20 | 1983-09-19 | Un procedimiento para la preparacion de nuevas idolonas. |
| ES531907A Granted ES531907A0 (es) | 1982-09-20 | 1984-04-25 | Un procedimiento para la preparacion de nuevas indolonas. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4476307A (es) |
| EP (1) | EP0104860B1 (es) |
| JP (1) | JPS5976058A (es) |
| KR (1) | KR860001270B1 (es) |
| AT (1) | ATE25972T1 (es) |
| AU (1) | AU543115B2 (es) |
| CA (1) | CA1194871A (es) |
| DD (1) | DD213211A5 (es) |
| DE (1) | DE3370325D1 (es) |
| DK (1) | DK157010C (es) |
| ES (3) | ES8503328A1 (es) |
| FI (1) | FI77446C (es) |
| GR (1) | GR79732B (es) |
| HU (1) | HU189747B (es) |
| IE (1) | IE55923B1 (es) |
| IL (1) | IL69758A (es) |
| NO (1) | NO161557C (es) |
| NZ (1) | NZ205638A (es) |
| PH (1) | PH18297A (es) |
| PL (3) | PL141876B1 (es) |
| PT (1) | PT77360B (es) |
| SU (1) | SU1272983A3 (es) |
| YU (4) | YU189283A (es) |
| ZA (1) | ZA836933B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4879391A (en) * | 1982-09-20 | 1989-11-07 | Pfizer Inc. | 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents |
| US4760083A (en) * | 1986-04-10 | 1988-07-26 | E. I. Dupont De Nemours & Company | 3,3-disubstituted indolines |
| US5128352A (en) * | 1989-01-10 | 1992-07-07 | Pfizer Inc. | Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides |
| US5078756A (en) * | 1990-01-12 | 1992-01-07 | Major Thomas O | Apparatus and method for purification and recovery of refrigerant |
| US5158969A (en) * | 1991-08-21 | 1992-10-27 | Neurosearch A/S | Indole derivatives as potassium channel blockers |
| US5760250A (en) * | 1991-11-05 | 1998-06-02 | Zeneca Limited | Process for the preparation of 3-(α-methoxy)methylenebenzofuranones and intermediates therefor |
| DE19949209A1 (de) * | 1999-10-13 | 2001-04-19 | Boehringer Ingelheim Pharma | In 5-Stellung substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel |
| WO2003027102A1 (en) * | 2001-09-27 | 2003-04-03 | Allergan, Inc. | 3-(arylamino)methylene-1, 3-dihydro-2h-indol-2-ones as kinase inhibitors |
| US20050101788A1 (en) * | 2002-03-27 | 2005-05-12 | Jacopo Zanon | Method for manufacture of sertindole |
| FR2847811B1 (fr) * | 2002-11-29 | 2005-01-07 | Oreal | Composition filtrante contenant au moins un derive du dibenzoylmethane et au moins un derive de 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one;procede de photostabilisation |
| FR2847813A1 (fr) * | 2002-11-29 | 2004-06-04 | Oreal | Compositions cosmetiques photoprotectrices contenant des derives de 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one et utilisations |
| ES2524922T3 (es) | 2005-05-10 | 2014-12-15 | Intermune, Inc. | Derivados de piridona para modular el sistema de proteína cinasa activada por estrés |
| JP5627574B2 (ja) | 2008-06-03 | 2014-11-19 | インターミューン, インコーポレイテッド | 炎症性および線維性疾患を治療するための化合物および方法 |
| WO2010070910A1 (ja) | 2008-12-19 | 2010-06-24 | 日本曹達株式会社 | 1-ヘテロジエン誘導体および有害生物防除剤 |
| BR112012011002B1 (pt) | 2009-11-12 | 2019-06-25 | Nippon Soda Company Limited | Derivado de 1-heterodieno e agente de controle de pragas |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHOD AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA |
| MX382781B (es) | 2014-04-02 | 2025-03-13 | Intermune Inc | Piridinonas anti-fibroticas. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3506683A (en) * | 1963-10-07 | 1970-04-14 | Upjohn Co | 3-(2-pyrrolidinylidene)-3h-indoles |
| GB1237008A (en) * | 1968-12-18 | 1971-06-30 | Pfizer Ltd | Novel indoline derivatives |
| US3723457A (en) * | 1969-09-30 | 1973-03-27 | Eisai Co Ltd | Indoline-2-one derivatives and preparation thereof |
| GB1374414A (en) * | 1972-06-12 | 1974-11-20 | Sterling Drug Inc | 1-acyl-3-amino-alkyl-indoles and their preparation |
| DE2557342A1 (de) * | 1975-12-19 | 1977-06-30 | Hoechst Ag | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
-
1982
- 1982-09-20 US US06/420,544 patent/US4476307A/en not_active Expired - Fee Related
-
1983
- 1983-09-16 CA CA000436845A patent/CA1194871A/en not_active Expired
- 1983-09-18 IL IL69758A patent/IL69758A/xx unknown
- 1983-09-19 IE IE2193/83A patent/IE55923B1/en not_active IP Right Cessation
- 1983-09-19 NO NO833367A patent/NO161557C/no unknown
- 1983-09-19 NZ NZ205638A patent/NZ205638A/en unknown
- 1983-09-19 PT PT77360A patent/PT77360B/pt not_active IP Right Cessation
- 1983-09-19 DD DD83254923A patent/DD213211A5/de unknown
- 1983-09-19 DK DK425383A patent/DK157010C/da not_active IP Right Cessation
- 1983-09-19 KR KR1019830004396A patent/KR860001270B1/ko not_active Expired
- 1983-09-19 FI FI833335A patent/FI77446C/fi not_active IP Right Cessation
- 1983-09-19 HU HU833235A patent/HU189747B/hu unknown
- 1983-09-19 ZA ZA836933A patent/ZA836933B/xx unknown
- 1983-09-19 EP EP83305484A patent/EP0104860B1/en not_active Expired
- 1983-09-19 SU SU833646758A patent/SU1272983A3/ru active
- 1983-09-19 AT AT83305484T patent/ATE25972T1/de not_active IP Right Cessation
- 1983-09-19 AU AU19252/83A patent/AU543115B2/en not_active Ceased
- 1983-09-19 DE DE8383305484T patent/DE3370325D1/de not_active Expired
- 1983-09-19 ES ES525737A patent/ES8503328A1/es not_active Expired
- 1983-09-19 GR GR72470A patent/GR79732B/el unknown
- 1983-09-20 PL PL1983250769A patent/PL141876B1/pl unknown
- 1983-09-20 PH PH29565A patent/PH18297A/en unknown
- 1983-09-20 JP JP58174025A patent/JPS5976058A/ja active Granted
- 1983-09-20 YU YU01892/83A patent/YU189283A/xx unknown
- 1983-09-20 PL PL1983243826A patent/PL141609B1/pl unknown
- 1983-09-20 PL PL1983250768A patent/PL141370B1/pl unknown
-
1984
- 1984-04-25 ES ES531907A patent/ES531907A0/es active Granted
- 1984-04-25 ES ES531908A patent/ES8505951A1/es not_active Expired
-
1986
- 1986-10-01 YU YU01692/86A patent/YU169286A/xx unknown
- 1986-10-01 YU YU01693/86A patent/YU169386A/xx unknown
- 1986-10-01 YU YU01691/86A patent/YU169186A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |