PH18065A - Therapeutically useful 1-alkyl-2-aminotetralin - Google Patents

Therapeutically useful 1-alkyl-2-aminotetralin

Info

Publication number
PH18065A
PH18065A PH27236A PH27236A PH18065A PH 18065 A PH18065 A PH 18065A PH 27236 A PH27236 A PH 27236A PH 27236 A PH27236 A PH 27236A PH 18065 A PH18065 A PH 18065A
Authority
PH
Philippines
Prior art keywords
carbon atoms
group
alkyl group
alkyl
compounds
Prior art date
Application number
PH27236A
Other languages
English (en)
Inventor
Folke Lars-Erik Arvidsson
Anette Margareta Johansson
Uli Alf Hacksell
Per Arvid Emil Garlsson
John Stephan Mikael Hjorth
Per Lennart Linberg
John Lars Gunnar Nilsson
Domingo Sanchez
Hakan Vilhelm Wikstrom
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of PH18065A publication Critical patent/PH18065A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PH27236A 1981-05-08 1982-05-05 Therapeutically useful 1-alkyl-2-aminotetralin PH18065A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8102908 1981-05-08

Publications (1)

Publication Number Publication Date
PH18065A true PH18065A (en) 1985-03-18

Family

ID=20343779

Family Applications (2)

Application Number Title Priority Date Filing Date
PH27236A PH18065A (en) 1981-05-08 1982-05-05 Therapeutically useful 1-alkyl-2-aminotetralin
PH30792A PH19585A (en) 1981-05-08 1984-06-08 1-alkyl-2-aminotetralin derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH30792A PH19585A (en) 1981-05-08 1984-06-08 1-alkyl-2-aminotetralin derivatives

Country Status (16)

Country Link
US (1) US4876284A (da)
EP (1) EP0064964B1 (da)
JP (1) JPS57192344A (da)
AT (1) ATE8874T1 (da)
AU (2) AU554206B2 (da)
CA (1) CA1236113A (da)
DE (1) DE3260529D1 (da)
DK (1) DK164937C (da)
ES (4) ES511986A0 (da)
FI (1) FI78067C (da)
GR (1) GR77121B (da)
IE (1) IE53143B1 (da)
IL (1) IL65501A (da)
NO (1) NO152902C (da)
NZ (1) NZ200526A (da)
PH (2) PH18065A (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
US4722933A (en) * 1985-12-20 1988-02-02 Nelson Research & Development Co. Substituted 2-aminotetralins
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
GB2157950B (en) * 1984-05-04 1988-11-02 Nelson Res & Dev Selective d-2 dopamine receptor agonist
AU573828B2 (en) * 1984-05-17 1988-06-23 E.R. Squibb & Sons, Inc. Tetrahydronaphthalenols
DE3479314D1 (en) * 1984-05-22 1989-09-14 Nelson Res & Dev Substituted 2-aminotetralins and processes for synthesis
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
US5091526A (en) * 1988-07-29 1992-02-25 Schering Corporation Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
JPH03505735A (ja) * 1988-07-29 1991-12-12 シェリング・コーポレーション ヘキサヒドロ―ベンゾ［ｄ］―ナフト［２，１―ｂ］アゼピンのための中間体の対掌体特異的合成のための方法
CA1335106C (en) * 1989-02-27 1995-04-04 John Mehnert Schaus Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
ATE172712T1 (de) * 1989-05-31 1998-11-15 Upjohn Co Zns-wirksame 8-heterocyclyl-2-aminotetralin derivate
IT1232160B (it) * 1989-07-31 1992-01-25 Sigma Tau Ind Farmaceuti 2-(n-acil)ammino-6,7-dimetossi tetraline, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' antiipertensiva che le contengono
EP0507863A4 (en) * 1989-12-28 1993-07-07 Virginia Commonwealth University Sigma receptor ligands and the use thereof
EP0471515B1 (en) * 1990-08-15 1997-03-05 Eli Lilly And Company Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes, 3-aminochromanes and 3-aminothiochromanes
CA2106197A1 (en) * 1991-04-26 1992-10-27 Montford F. Piercey Method of treating/preventing substance abuse
WO1993000313A2 (en) * 1991-06-27 1993-01-07 Virginia Commonwealth University Sigma receptor ligands and the use thereof
IT1251877B (it) * 1991-09-26 1995-05-26 Zambon Spa Processo per la preparazione di 2-ammino-5,6 dimetossi-tetralina
EP0697894A4 (en) * 1993-03-31 1996-05-01 Univ Pennsylvania DOPAMINE D-3 AND SEROTONIN (5-HT 1A) RECEPTOR LIGANDS AND IMAGING AGENTS
CA2166100A1 (en) * 1993-06-23 1995-01-05 Richard A. Glennon Sigma receptor ligands and the use thereof
GB9315566D0 (en) * 1993-07-28 1993-09-08 Smithkline Beecham Plc Medicaments
DE69608551T2 (de) * 1995-03-27 2001-01-18 Smithkline Beecham P.L.C., Brentford Bicyclische amin-derivate und ihre verwendung als antipsychotische wirkstoffe
US5646188A (en) * 1995-07-05 1997-07-08 Teva Pharmaceutical Industries, Ltd. Polyamine derivatives of 1-aminoindan
NZ510988A (en) * 1998-10-07 2005-01-28 Ortho Mcneil Pharm Inc N-aralkylaminotetralins useful as ligands for the neuropeptide Y5 receptor
AU2003241453A1 (en) 2002-05-17 2003-12-02 Janssen Pharmaceutica N.V. Aminotetralin-derived urea modulators of vanilloid vr1 receptor
EP2098511A1 (en) 2008-03-07 2009-09-09 Solvias AG Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring
DE102010020553A1 (de) 2010-05-14 2011-11-17 Bayer Schering Pharma Aktiengesellschaft Substituierte 8-Alkoxy-2-aminotetralin-Derivate und ihre Verwendung
WO2014012935A1 (de) 2012-07-20 2014-01-23 Bayer Pharma Aktiengesellschaft Substituierte aminoindan- und aminotetralin-carbonsäuren und ihre verwendung
EP2875003B1 (de) 2012-07-20 2016-11-16 Bayer Pharma Aktiengesellschaft Neue 5-aminotetrahydrochinolin-2-carbonsäuren und ihre verwendung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1017359A (en) * 1972-07-03 1977-09-13 Frederic P. Hauck Substituted cyclic polymethylene phenols
JPS5124508B2 (da) * 1972-08-14 1976-07-24
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
DE3062971D1 (en) * 1979-09-14 1983-06-09 Sandoz Ag Derivatives of tetraline, their preparation and medicaments containing these compounds
AU7179781A (en) * 1980-05-29 1981-12-21 Astra Lakemedel Aktiebolag Therapeutically useful tetralin derivatives
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
FR2512814A1 (fr) * 1981-09-16 1983-03-18 Synthelabo Derives d'amino-2 tetrahydro-1,2,3,4 naphtalene, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
IL65501A (en) 1986-04-29
IE53143B1 (en) 1988-07-20
ES8504666A1 (es) 1985-05-01
ES8306708A1 (es) 1983-06-01
FI78067B (fi) 1989-02-28
NZ200526A (en) 1985-09-13
EP0064964B1 (en) 1984-08-08
ES8602603A1 (es) 1985-12-01
DK164937C (da) 1993-02-01
AU8340982A (en) 1982-11-11
JPS57192344A (en) 1982-11-26
FI821598A0 (fi) 1982-05-06
EP0064964A1 (en) 1982-11-17
US4876284A (en) 1989-10-24
JPH0419221B2 (da) 1992-03-30
AU554206B2 (en) 1986-08-14
ATE8874T1 (de) 1984-08-15
CA1236113A (en) 1988-05-03
FI821598L (fi) 1982-11-09
PH19585A (en) 1986-05-26
DK202882A (da) 1982-11-09
DE3260529D1 (en) 1984-09-13
ES535882A0 (es) 1985-12-01
AU2587984A (en) 1984-06-28
ES8506591A1 (es) 1985-08-01
NO152902C (no) 1985-12-11
FI78067C (fi) 1989-06-12
ES519615A0 (es) 1985-05-01
NO152902B (no) 1985-09-02
NO821494L (no) 1982-11-09
ES529311A0 (es) 1985-08-01
IL65501A0 (en) 1982-07-30
AU572497B2 (en) 1988-05-12
IE821076L (en) 1982-11-08
DK164937B (da) 1992-09-14
GR77121B (da) 1984-09-07
ES511986A0 (es) 1983-06-01

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