PH13780A - N-tetrahydrofurfuryl-noroxynorphones,their salts,and analgesic compositions and methods employing them - Google Patents

N-tetrahydrofurfuryl-noroxynorphones,their salts,and analgesic compositions and methods employing them

Info

Publication number
PH13780A
PH13780A PH18780A PH18780A PH13780A PH 13780 A PH13780 A PH 13780A PH 18780 A PH18780 A PH 18780A PH 18780 A PH18780 A PH 18780A PH 13780 A PH13780 A PH 13780A
Authority
PH
Philippines
Prior art keywords
noroxynorphones
tetrahydrofurfuryl
salts
methods employing
analgesic compositions
Prior art date
Application number
PH18780A
Other languages
English (en)
Inventor
K Stockhaus
G Walther
H Wick
H Merz
A Langbein
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of PH13780A publication Critical patent/PH13780A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH18780A 1975-08-27 1976-08-12 N-tetrahydrofurfuryl-noroxynorphones,their salts,and analgesic compositions and methods employing them PH13780A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752538075 DE2538075A1 (de) 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
PH13780A true PH13780A (en) 1980-09-26

Family

ID=5954931

Family Applications (1)

Application Number Title Priority Date Filing Date
PH18780A PH13780A (en) 1975-08-27 1976-08-12 N-tetrahydrofurfuryl-noroxynorphones,their salts,and analgesic compositions and methods employing them

Country Status (33)

Country Link
US (1) US4100288A (fr)
JP (1) JPS5231100A (fr)
AT (1) AT350737B (fr)
AU (1) AU499926B2 (fr)
BE (1) BE845563A (fr)
BG (2) BG27545A3 (fr)
CA (1) CA1068266A (fr)
CH (5) CH622521A5 (fr)
CS (2) CS192564B2 (fr)
DD (1) DD127145A5 (fr)
DE (1) DE2538075A1 (fr)
DK (1) DK143278C (fr)
ES (5) ES450897A1 (fr)
FI (1) FI762430A (fr)
FR (1) FR2321888A1 (fr)
GB (1) GB1519719A (fr)
GR (1) GR61158B (fr)
HU (1) HU176929B (fr)
IE (1) IE44069B1 (fr)
IL (1) IL50355A (fr)
LU (1) LU75667A1 (fr)
MX (1) MX4133E (fr)
NL (1) NL7609485A (fr)
NO (1) NO145793C (fr)
NZ (1) NZ181864A (fr)
PH (1) PH13780A (fr)
PL (2) PL110724B1 (fr)
PT (1) PT65521B (fr)
RO (1) RO69457A (fr)
SE (1) SE7609495L (fr)
SU (2) SU612631A3 (fr)
YU (1) YU208176A (fr)
ZA (1) ZA765120B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
DE3220831A1 (de) * 1982-06-03 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
JP5586223B2 (ja) * 2006-04-21 2014-09-10 ネクター セラピューティクス モルヒノンの立体選択的還元
WO2012005795A1 (fr) 2010-07-08 2012-01-12 Alkermes, Inc. Procédé de synthèse de morphinanes substitués
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
EP3003311A2 (fr) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Méthodes de traitement de symptômes de la dépression
AU2014268361B2 (en) 2013-05-24 2018-09-06 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
CN111836813A (zh) * 2018-02-23 2020-10-27 罗德科技公司 新型阿片样化合物及其用途
EP4243768A1 (fr) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Comprimé multicouche à libération immédiate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH446370A (de) 1964-03-05 1967-11-15 Hoffmann La Roche Verfahren zur Herstellung von Phenanthren-Derivaten
DE2238839A1 (de) * 1972-08-07 1974-02-14 Boehringer Sohn Ingelheim Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
CH624115A5 (fr) 1981-07-15
ES454085A1 (es) 1977-11-16
DD127145A5 (fr) 1977-09-07
AU499926B2 (en) 1979-05-03
FI762430A (fr) 1977-02-28
MX4133E (es) 1982-01-06
LU75667A1 (fr) 1977-09-13
PL110724B1 (en) 1980-07-31
GR61158B (en) 1978-09-30
DE2538075A1 (de) 1977-03-17
NO762932L (fr) 1977-03-01
IE44069B1 (en) 1981-08-12
NL7609485A (nl) 1977-03-01
ES454086A1 (es) 1977-11-16
CH624116A5 (fr) 1981-07-15
CS192599B2 (en) 1979-08-31
IL50355A0 (en) 1976-10-31
DK143278C (da) 1981-12-07
BE845563A (fr) 1977-02-28
JPS5231100A (en) 1977-03-09
NZ181864A (en) 1978-06-20
IL50355A (en) 1979-11-30
CS192564B2 (en) 1979-08-31
YU208176A (en) 1982-08-31
BG27546A4 (en) 1979-11-12
DK386876A (da) 1977-02-28
SE7609495L (sv) 1977-02-28
FR2321888B1 (fr) 1980-01-11
ES454087A2 (es) 1977-11-16
US4100288A (en) 1978-07-11
DK143278B (da) 1981-08-03
ZA765120B (en) 1978-05-30
FR2321888A1 (fr) 1977-03-25
ES454084A1 (es) 1977-11-16
PL192020A1 (pl) 1979-03-12
SU612631A3 (ru) 1978-06-25
SU638262A3 (ru) 1978-12-15
HU176929B (hu) 1981-06-28
PT65521A (de) 1976-09-01
ES450897A1 (es) 1977-12-01
CH622521A5 (fr) 1981-04-15
IE44069L (en) 1977-02-27
PT65521B (de) 1978-07-04
CH624117A5 (fr) 1981-07-15
BG27545A3 (en) 1979-11-12
GB1519719A (en) 1978-08-02
ATA553976A (de) 1978-11-15
CH624114A5 (fr) 1981-07-15
CA1068266A (fr) 1979-12-18
PL109091B1 (en) 1980-05-31
AT350737B (de) 1979-06-11
NO145793C (no) 1982-06-02
RO69457A (fr) 1981-04-30
NO145793B (no) 1982-02-22
AU1720176A (en) 1978-03-02

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