PH12022550474A1 - Aqueous ophthalmic composition comprising diquafosol or salt thereof and polyvinylpyrrolidone - Google Patents
Aqueous ophthalmic composition comprising diquafosol or salt thereof and polyvinylpyrrolidoneInfo
- Publication number
- PH12022550474A1 PH12022550474A1 PH1/2022/550474A PH12022550474A PH12022550474A1 PH 12022550474 A1 PH12022550474 A1 PH 12022550474A1 PH 12022550474 A PH12022550474 A PH 12022550474A PH 12022550474 A1 PH12022550474 A1 PH 12022550474A1
- Authority
- PH
- Philippines
- Prior art keywords
- polyvinylpyrrolidone
- diquafosol
- aqueous ophthalmic
- ophthalmic composition
- salt
- Prior art date
Links
- NMLMACJWHPHKGR-NCOIDOBVSA-N P(1),P(4)-bis(uridin-5'-yl) tetraphosphate Chemical compound N1([C@@H]2O[C@@H]([C@H]([C@H]2O)O)COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N2C(NC(=O)C=C2)=O)O)O)C=CC(=O)NC1=O NMLMACJWHPHKGR-NCOIDOBVSA-N 0.000 title abstract 4
- 229950003529 diquafosol Drugs 0.000 title abstract 4
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 title abstract 4
- 229920000036 polyvinylpyrrolidone Polymers 0.000 title abstract 4
- 239000001267 polyvinylpyrrolidone Substances 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 title abstract 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 abstract 4
- 208000003556 Dry Eye Syndromes Diseases 0.000 abstract 2
- 206010013774 Dry eye Diseases 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 2
- 229910001961 silver nitrate Inorganic materials 0.000 abstract 2
- 229910052708 sodium Inorganic materials 0.000 abstract 2
- 239000011734 sodium Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019154525 | 2019-08-27 | ||
| PCT/JP2020/031917 WO2021039748A1 (ja) | 2019-08-27 | 2020-08-25 | ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12022550474A1 true PH12022550474A1 (en) | 2023-03-06 |
Family
ID=74685901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH1/2022/550474A PH12022550474A1 (en) | 2019-08-27 | 2020-08-25 | Aqueous ophthalmic composition comprising diquafosol or salt thereof and polyvinylpyrrolidone |
Country Status (7)
| Country | Link |
|---|---|
| JP (3) | JP6966667B2 (https=) |
| KR (2) | KR102656181B1 (https=) |
| CN (2) | CN114286670B (https=) |
| MY (1) | MY209059A (https=) |
| PH (1) | PH12022550474A1 (https=) |
| TW (1) | TWI848171B (https=) |
| WO (1) | WO2021039748A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117137866A (zh) * | 2018-02-28 | 2023-12-01 | 参天制药株式会社 | 含有地夸磷索及阳离子性聚合物的眼科用组合物 |
| JP6966667B2 (ja) * | 2019-08-27 | 2021-11-17 | 参天製薬株式会社 | ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 |
| CA3215750A1 (en) * | 2021-03-30 | 2022-10-06 | Senju Pharmaceutical Co., Ltd. | Suspension containing heterocyclidene acetamide derivative |
| CN114646705A (zh) * | 2022-03-22 | 2022-06-21 | 武汉绿合医药科技有限公司 | 一种地夸磷索钠滴眼液有关物质含量检测方法 |
| JP7245383B1 (ja) | 2022-09-20 | 2023-03-23 | 参天製薬株式会社 | ジクアホソルまたはその塩を含有する眼科用組成物のｐＨの低下を抑制する方法 |
| KR20250160050A (ko) | 2024-05-03 | 2025-11-11 | 삼천당제약주식회사 | 물리화학적 특성이 개선된 안구건조증 예방 또는 치료용 약학 조성물 |
| CN119970633A (zh) * | 2025-03-26 | 2025-05-13 | 苏州乐珠制药有限公司 | 一种地夸磷索钠滴眼液及其制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0365270A (ja) | 1989-07-31 | 1991-03-20 | Kanzaki Paper Mfg Co Ltd | 塗布シートの製造方法 |
| JPH0365270U (https=) | 1989-10-31 | 1991-06-25 | ||
| US5358706A (en) * | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
| CA2125060C (en) * | 1993-07-02 | 1999-03-30 | Henry P. Dabrowski | Ophthalmic solution for artificial tears |
| US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
| US5900407A (en) * | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
| KR100549904B1 (ko) * | 1996-03-27 | 2006-05-16 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 우리딘트리포스페이트및관련화합물을함유하는섬모운동장해치료용약학조성물 |
| US6274626B1 (en) * | 1998-12-22 | 2001-08-14 | Bausch & Lomb Incorporated | Pheniramine-containing compositions and method for treating allergic responses |
| AU2225701A (en) * | 1999-12-27 | 2001-07-09 | Santen Pharmaceutical Co. Ltd. | System for stabilizing lacrimal fluid layer |
| AU2001260643B9 (en) * | 2000-05-30 | 2006-10-19 | Merck Sharp & Dohme Corp. | Ectocornea extension promoters |
| KR20070114130A (ko) * | 2005-02-14 | 2007-11-29 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | 착용감이 편안한 안용 장치 및 이의 제조방법 |
| CN106729718A (zh) * | 2010-09-10 | 2017-05-31 | 参天制药株式会社 | 以组合p2y2受体激动剂和透明质酸或其盐为特征的干眼症治疗剂 |
| US20110052678A1 (en) * | 2010-11-05 | 2011-03-03 | Shantha Totada R | Method for treating age related macular degeneration |
| UA113839C2 (xx) * | 2010-12-28 | 2017-03-27 | Очний розчин, який містить диквафозол, спосіб його отримання і спосіб інгібування утворення нерозчинного осаду | |
| KR20120077080A (ko) | 2010-12-30 | 2012-07-10 | 동우 화인켐 주식회사 | 광학필름 및 이를 이용한 백라이트 유닛 |
| US20160213708A1 (en) * | 2012-01-08 | 2016-07-28 | Medicure Technologies Ltd. | Ophthalmic composition |
| KR101536885B1 (ko) * | 2012-03-26 | 2015-07-14 | 산텐 세이야꾸 가부시키가이샤 | 디쿠아포솔 함유 점안액 |
| JP2015032653A (ja) | 2013-08-01 | 2015-02-16 | 株式会社東芝 | 固体撮像装置 |
| JP6267003B2 (ja) | 2014-02-27 | 2018-01-24 | 参天製薬株式会社 | ジクアホソルまたはその塩およびレバミピドまたはその塩を組み合わせたことを特徴とする涙液分泌促進剤 |
| EP3139903B1 (en) * | 2014-05-07 | 2019-07-03 | Croma-Pharma Gesellschaft m.b.H. | Aqueous ophthalmic solution and method for treating dry eye syndrome |
| KR102330736B1 (ko) * | 2014-12-25 | 2021-11-23 | 산텐 세이야꾸 가부시키가이샤 | 수성 점안액 |
| CN107635565A (zh) * | 2015-06-05 | 2018-01-26 | 参天制药株式会社 | 以向佩戴有软性隐形眼镜的干眼症患者的眼中滴入的方式使用为特征的干眼症治疗剂 |
| CN107837276A (zh) * | 2016-09-19 | 2018-03-27 | 刘力 | 局部给药的药物组合物 |
| CN117137866A (zh) * | 2018-02-28 | 2023-12-01 | 参天制药株式会社 | 含有地夸磷索及阳离子性聚合物的眼科用组合物 |
| JP6966667B2 (ja) * | 2019-08-27 | 2021-11-17 | 参天製薬株式会社 | ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 |
-
2020
- 2020-08-25 JP JP2021521065A patent/JP6966667B2/ja active Active
- 2020-08-25 MY MYPI2022001012A patent/MY209059A/en unknown
- 2020-08-25 KR KR1020227009546A patent/KR102656181B1/ko active Active
- 2020-08-25 PH PH1/2022/550474A patent/PH12022550474A1/en unknown
- 2020-08-25 CN CN202080059970.2A patent/CN114286670B/zh active Active
- 2020-08-25 WO PCT/JP2020/031917 patent/WO2021039748A1/ja not_active Ceased
- 2020-08-25 CN CN202311818685.6A patent/CN117771172A/zh active Pending
- 2020-08-25 TW TW109128895A patent/TWI848171B/zh active
- 2020-08-25 KR KR1020247011257A patent/KR20240049646A/ko active Pending
-
2021
- 2021-10-20 JP JP2021171358A patent/JP7614069B2/ja active Active
-
2024
- 2024-12-25 JP JP2024228577A patent/JP2025031918A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN114286670B (zh) | 2024-01-16 |
| JP2025031918A (ja) | 2025-03-07 |
| CN117771172A (zh) | 2024-03-29 |
| JP2022003099A (ja) | 2022-01-11 |
| CN114286670A (zh) | 2022-04-05 |
| TWI848171B (zh) | 2024-07-11 |
| KR20220052971A (ko) | 2022-04-28 |
| JP7614069B2 (ja) | 2025-01-15 |
| JPWO2021039748A1 (ja) | 2021-09-30 |
| TW202122094A (zh) | 2021-06-16 |
| KR102656181B1 (ko) | 2024-04-08 |
| KR20240049646A (ko) | 2024-04-16 |
| JP6966667B2 (ja) | 2021-11-17 |
| WO2021039748A1 (ja) | 2021-03-04 |
| MY209059A (en) | 2025-06-18 |
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