CN114286670B - 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物 - Google Patents

含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物 Download PDF

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Publication number
CN114286670B
CN114286670B CN202080059970.2A CN202080059970A CN114286670B CN 114286670 B CN114286670 B CN 114286670B CN 202080059970 A CN202080059970 A CN 202080059970A CN 114286670 B CN114286670 B CN 114286670B
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eye
drops
ophthalmic composition
aqueous ophthalmic
sodium
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CN114286670A (zh
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森岛健司
浅田博之
桃川雄介
神村明日香
远藤健一
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Santen Pharmaceutical Co Ltd
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Santen Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN202080059970.2A 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物 Active CN114286670B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311818685.6A CN117771172A (zh) 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物

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JP2019154525 2019-08-27
JP2019-154525 2019-08-27
PCT/JP2020/031917 WO2021039748A1 (ja) 2019-08-27 2020-08-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

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CN202311818685.6A Division CN117771172A (zh) 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物

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CN114286670A CN114286670A (zh) 2022-04-05
CN114286670B true CN114286670B (zh) 2024-01-16

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CN202080059970.2A Active CN114286670B (zh) 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物
CN202311818685.6A Pending CN117771172A (zh) 2019-08-27 2020-08-25 含有地夸磷索或其盐、及聚乙烯吡咯烷酮的水性眼科用组合物

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Country Status (7)

Country Link
JP (3) JP6966667B2 (https=)
KR (2) KR102656181B1 (https=)
CN (2) CN114286670B (https=)
MY (1) MY209059A (https=)
PH (1) PH12022550474A1 (https=)
TW (1) TWI848171B (https=)
WO (1) WO2021039748A1 (https=)

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CN117137866A (zh) * 2018-02-28 2023-12-01 参天制药株式会社 含有地夸磷索及阳离子性聚合物的眼科用组合物
JP6966667B2 (ja) * 2019-08-27 2021-11-17 参天製薬株式会社 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物
CA3215750A1 (en) * 2021-03-30 2022-10-06 Senju Pharmaceutical Co., Ltd. Suspension containing heterocyclidene acetamide derivative
CN114646705A (zh) * 2022-03-22 2022-06-21 武汉绿合医药科技有限公司 一种地夸磷索钠滴眼液有关物质含量检测方法
JP7245383B1 (ja) 2022-09-20 2023-03-23 参天製薬株式会社 ジクアホソルまたはその塩を含有する眼科用組成物のｐＨの低下を抑制する方法
KR20250160050A (ko) 2024-05-03 2025-11-11 삼천당제약주식회사 물리화학적 특성이 개선된 안구건조증 예방 또는 치료용 약학 조성물
CN119970633A (zh) * 2025-03-26 2025-05-13 苏州乐珠制药有限公司 一种地夸磷索钠滴眼液及其制备方法

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CN111757742A (zh) * 2018-02-28 2020-10-09 参天制药株式会社 含有地夸磷索及阳离子性聚合物的眼科用组合物

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US5591426A (en) * 1993-07-02 1997-01-07 Bausch & Lomb Incorporated Ophthalmic solution for artificial tears
US6274626B1 (en) * 1998-12-22 2001-08-14 Bausch & Lomb Incorporated Pheniramine-containing compositions and method for treating allergic responses
CN1413114A (zh) * 1999-12-27 2003-04-23 参天制药株式会社 用于稳定泪液层的体系
CN103096929A (zh) * 2010-09-10 2013-05-08 参天制药株式会社 以组合p2y2受体激动剂和透明质酸或其盐为特征的干眼症治疗剂、干眼症的治疗方法、及干眼症治疗剂的应用
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Publication number Publication date
JP2025031918A (ja) 2025-03-07
CN117771172A (zh) 2024-03-29
JP2022003099A (ja) 2022-01-11
CN114286670A (zh) 2022-04-05
TWI848171B (zh) 2024-07-11
KR20220052971A (ko) 2022-04-28
JP7614069B2 (ja) 2025-01-15
JPWO2021039748A1 (ja) 2021-09-30
TW202122094A (zh) 2021-06-16
PH12022550474A1 (en) 2023-03-06
KR102656181B1 (ko) 2024-04-08
KR20240049646A (ko) 2024-04-16
JP6966667B2 (ja) 2021-11-17
WO2021039748A1 (ja) 2021-03-04
MY209059A (en) 2025-06-18

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