PH12016500783A1 - Suspension and clustering of human pluripotent stem cells for differentation into pancreatic endocrine cells - Google Patents
Suspension and clustering of human pluripotent stem cells for differentation into pancreatic endocrine cellsInfo
- Publication number
- PH12016500783A1 PH12016500783A1 PH12016500783A PH12016500783A PH12016500783A1 PH 12016500783 A1 PH12016500783 A1 PH 12016500783A1 PH 12016500783 A PH12016500783 A PH 12016500783A PH 12016500783 A PH12016500783 A PH 12016500783A PH 12016500783 A1 PH12016500783 A1 PH 12016500783A1
- Authority
- PH
- Philippines
- Prior art keywords
- clustering
- suspension
- pluripotent stem
- differentation
- cells
- Prior art date
Links
- 210000001778 pluripotent stem cell Anatomy 0.000 title abstract 2
- 239000000725 suspension Substances 0.000 title abstract 2
- 210000003890 endocrine cell Anatomy 0.000 title 1
- 230000009996 pancreatic endocrine effect Effects 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 2
- 230000004069 differentiation Effects 0.000 abstract 2
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 abstract 1
- 210000002064 heart cell Anatomy 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C12N5/0075—General culture methods using substrates using microcarriers
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
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- C12N2500/00—Specific components of cell culture medium
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- C12N2501/10—Growth factors
- C12N2501/117—Keratinocyte growth factors (KGF-1, i.e. FGF-7; KGF-2, i.e. FGF-12)
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- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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- C12N2501/10—Growth factors
- C12N2501/19—Growth and differentiation factors [GDF]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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- C12N2501/72—Transferases [EC 2.]
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
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- C12N2531/00—Microcarriers
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- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361962158P | 2013-11-01 | 2013-11-01 | |
US13/998,974 US10377989B2 (en) | 2012-12-31 | 2013-12-30 | Methods for suspension cultures of human pluripotent stem cells |
PCT/US2014/042796 WO2015065537A1 (en) | 2013-11-01 | 2014-06-17 | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
Publications (1)
Publication Number | Publication Date |
---|---|
PH12016500783A1 true PH12016500783A1 (en) | 2016-06-13 |
Family
ID=53004904
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH12016500783A PH12016500783A1 (en) | 2013-11-01 | 2016-04-27 | Suspension and clustering of human pluripotent stem cells for differentation into pancreatic endocrine cells |
PH12016500782A PH12016500782A1 (en) | 2013-11-01 | 2016-04-27 | Suspension and clustering of human pluripotent stem cells for differentation into pancreatic endocrine cells |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH12016500782A PH12016500782A1 (en) | 2013-11-01 | 2016-04-27 | Suspension and clustering of human pluripotent stem cells for differentation into pancreatic endocrine cells |
Country Status (12)
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2928639A1 (en) * | 2013-11-01 | 2015-05-07 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
EP3474866A4 (en) * | 2016-06-23 | 2020-02-26 | Tithon Biotech, Inc. | CELLS EXPRESSING THE PARATHYROID HORMONE RECEPTOR 1 AND USES THEREOF |
CN110167455B (zh) | 2016-11-10 | 2022-10-11 | 韦尔赛特公司 | 含有pdx1胰腺内胚层细胞的细胞递送装置及其方法 |
CA3042562C (en) * | 2016-11-16 | 2023-02-28 | Cynata Therapeutics Limited | Pluripotent stem cell assay |
US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
EP3654996A4 (en) * | 2017-07-21 | 2021-03-24 | Semma Therapeutics, Inc. | REAGGREGATION OF PANCREAS BETA CELLS FROM STEM CELLS |
JP7000896B2 (ja) * | 2017-08-23 | 2022-01-19 | 王子ホールディングス株式会社 | 細胞シート形成部材、細胞シート形成部材の製造方法、および、細胞シートの製造方法 |
JP2021509812A (ja) * | 2018-01-05 | 2021-04-08 | プレートレット バイオジェネシス, インコーポレイテッド | 巨核球を産生するための組成物および方法 |
EP3740566A4 (en) | 2018-01-18 | 2021-10-27 | Agency for Science, Technology and Research | PROCESS FOR DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELL LINES IN SUSPENSION CULTURE |
KR102115360B1 (ko) * | 2018-05-30 | 2020-05-26 | 주식회사 바이블리오테카 | 성체 줄기세포 배양액 및 그 제조방법 |
US10724052B2 (en) | 2018-09-07 | 2020-07-28 | Crispr Therapeutics Ag | Universal donor cells |
US20220234006A1 (en) | 2019-05-31 | 2022-07-28 | W. L. Gore & Associates, Inc. | A biocompatible membrane composite |
JP2022535239A (ja) | 2019-05-31 | 2022-08-05 | ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティド | 生体適合性メンブレン複合体 |
WO2020243665A1 (en) | 2019-05-31 | 2020-12-03 | W. L. Gore & Associates, Inc. | A biocompatible membrane composite |
CA3139292A1 (en) | 2019-05-31 | 2020-12-03 | Timothy M. BRUHN | Cell encapsulation devices with controlled oxygen diffusion distances |
CA3151339A1 (en) * | 2019-08-27 | 2021-03-04 | United Therapeutics Corporation | Methods and compositions for culturing alveolar cells |
US11116797B2 (en) | 2019-09-05 | 2021-09-14 | Crispr Therapeutics Ag | Universal donor cells |
US11118196B2 (en) | 2019-09-05 | 2021-09-14 | Crispr Therapeutics Ag | Universal donor cells |
EP4061929A1 (en) * | 2019-11-22 | 2022-09-28 | Novo Nordisk A/S | Spin-aggregated neural microspheres and the application thereof |
US11578309B2 (en) | 2020-12-31 | 2023-02-14 | Crispr Therapeutics Ag | Universal donor cells |
JPWO2022203051A1 (enrdf_load_stackoverflow) * | 2021-03-25 | 2022-09-29 | ||
CN116218766A (zh) * | 2023-04-21 | 2023-06-06 | 北京意胜生物科技有限公司 | 一种制备胰腺前体细胞的方法、培养基及其应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2351648C2 (ru) * | 2001-11-09 | 2009-04-10 | Артесел Сайенсиз, Инк. | Дифференцировка стромальных клеток, полученных из жировой ткани, в эндокринные клетки поджелудочной железы и их использование |
EP2733203B1 (en) * | 2006-08-02 | 2018-10-10 | Technion Research & Development Foundation Ltd. | Methods of expanding embryonic stem cells in a suspension culture |
JP5067949B2 (ja) * | 2006-11-09 | 2012-11-07 | 独立行政法人国立国際医療研究センター | 霊長類動物胚性幹細胞の培養及び継代方法、並びにその分化誘導方法 |
WO2008148105A1 (en) * | 2007-05-25 | 2008-12-04 | Medistem Laboratories, Inc. | Endometrial stem cells and methods of making and using same |
WO2009006399A1 (en) * | 2007-07-01 | 2009-01-08 | Lifescan | Single pluripotent stem cell culture |
SG188918A1 (enrdf_load_stackoverflow) * | 2008-03-17 | 2013-04-30 | Agency Science Tech & Res | |
BRPI0914116A2 (pt) * | 2008-06-30 | 2019-09-17 | Centocor Ortho Biotech Inc | diferenciação de células-tronco pluripotentes |
US8008075B2 (en) * | 2008-11-04 | 2011-08-30 | Viacyte, Inc. | Stem cell aggregate suspension compositions and methods of differentiation thereof |
EP2464723B1 (en) * | 2009-08-12 | 2016-06-22 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into neural precursor cells |
EP2582795B1 (en) * | 2010-06-15 | 2017-04-12 | Kyoto University | Method for selecting human induced pluripotent stem cells |
EP2853589B1 (en) * | 2010-08-31 | 2017-12-27 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
WO2012117333A1 (en) * | 2011-02-28 | 2012-09-07 | Stempeutics Research Malaysia Sdn Bhd | Isolation and expansion of adult stem cells, their therapeutic composition and uses thereof |
WO2013056072A1 (en) * | 2011-10-13 | 2013-04-18 | Wisconsin Alumni Research Foundation | Generation of cardiomyocytes from human pluripotent stem cells |
BR112014015417A8 (pt) * | 2011-12-22 | 2017-07-04 | Janssen Biotech Inc | diferenciação de células-tronco embrionárias humanas em células positivas de insulina hormonal únicas |
US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
EP2938722B1 (en) * | 2012-12-31 | 2021-12-08 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent cells for differentiation into pancreatic endocrine cells |
CA2928639A1 (en) * | 2013-11-01 | 2015-05-07 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
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2014
- 2014-05-21 CA CA2928639A patent/CA2928639A1/en not_active Abandoned
- 2014-05-21 MX MX2016005657A patent/MX2016005657A/es unknown
- 2014-05-21 KR KR1020167014409A patent/KR20160079072A/ko not_active Ceased
- 2014-05-21 SG SG11201603045VA patent/SG11201603045VA/en unknown
- 2014-05-21 KR KR1020187034291A patent/KR20180128529A/ko not_active Abandoned
- 2014-05-21 JP JP2016527338A patent/JP2016534731A/ja active Pending
- 2014-05-21 WO PCT/US2014/038993 patent/WO2015065524A2/en active Application Filing
- 2014-05-21 EP EP14857034.4A patent/EP3063268A4/en not_active Withdrawn
- 2014-05-21 RU RU2016121409A patent/RU2689710C2/ru active
- 2014-05-21 AU AU2014342995A patent/AU2014342995C1/en not_active Ceased
- 2014-05-21 CN CN201480059910.5A patent/CN105793413A/zh active Pending
- 2014-06-17 CN CN201480059902.0A patent/CN105683362A/zh active Pending
- 2014-06-17 RU RU2016121404A patent/RU2016121404A/ru not_active Application Discontinuation
- 2014-06-17 BR BR112016009393A patent/BR112016009393A8/pt not_active Application Discontinuation
- 2014-06-17 CA CA2928741A patent/CA2928741A1/en not_active Abandoned
- 2014-06-17 SG SG11201603047PA patent/SG11201603047PA/en unknown
- 2014-06-17 WO PCT/US2014/042796 patent/WO2015065537A1/en active Application Filing
- 2014-06-17 MX MX2016005658A patent/MX2016005658A/es unknown
- 2014-06-17 KR KR1020167014406A patent/KR20160079071A/ko not_active Abandoned
- 2014-06-17 EP EP14859059.9A patent/EP3063269A4/en not_active Withdrawn
- 2014-06-17 JP JP2016527450A patent/JP2017500013A/ja active Pending
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2016
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2018
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