PH12014502571B1 - Ophthalmic compositions with improved dessication protection and retention - Google Patents
Ophthalmic compositions with improved dessication protection and retentionInfo
- Publication number
- PH12014502571B1 PH12014502571B1 PH1/2014/502571A PH12014502571A PH12014502571B1 PH 12014502571 B1 PH12014502571 B1 PH 12014502571B1 PH 12014502571 A PH12014502571 A PH 12014502571A PH 12014502571 B1 PH12014502571 B1 PH 12014502571B1
- Authority
- PH
- Philippines
- Prior art keywords
- dessication
- retention
- protection
- improved
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 230000014759 maintenance of location Effects 0.000 title 1
- 244000007835 Cyamopsis tetragonoloba Species 0.000 abstract 2
- -1 hydroxypropyl Chemical group 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 abstract 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- 229920000926 Galactomannan Polymers 0.000 abstract 1
- 239000000607 artificial tear Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261642901P | 2012-05-04 | 2012-05-04 | |
| PCT/US2013/039487 WO2013166399A1 (en) | 2012-05-04 | 2013-05-03 | Ophthalmic compositions with improved dessication protection and retention |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PH12014502571A1 PH12014502571A1 (en) | 2015-01-21 |
| PH12014502571B1 true PH12014502571B1 (en) | 2022-04-29 |
Family
ID=48464107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH1/2014/502571A PH12014502571B1 (en) | 2012-05-04 | 2013-05-03 | Ophthalmic compositions with improved dessication protection and retention |
Country Status (19)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6357228B2 (ja) | 2013-07-10 | 2018-07-11 | マトリックス バイオロジー インスティテュート | 高い弾性を有するヒアルロナンの組成物およびその使用 |
| US10245324B2 (en) * | 2014-10-31 | 2019-04-02 | Johnson & Johnson Consumer Inc. | Ophthalmic composition |
| CN105311042B (zh) * | 2015-09-07 | 2019-04-12 | 广州国宇医药科技有限公司 | 一种糖醇组合物在制备治疗干眼症的药物中的应用 |
| PL3842047T3 (pl) | 2015-09-24 | 2024-10-28 | Matrix Biology Institute | Kompozycje hialuronanu o wysokiej elastyczności i sposoby ich zastosowania |
| US10632202B2 (en) | 2016-03-04 | 2020-04-28 | Johnson & Johnson Consumer Inc. | Preservative containing compositions |
| TWI884130B (zh) * | 2018-02-21 | 2025-05-21 | 瑞士商愛爾康公司 | 基於脂質的眼用乳劑 |
| TWI826685B (zh) * | 2019-05-02 | 2023-12-21 | 瑞士商愛爾康公司 | 可溶解聚合物眼睛插入物及其使用方法 |
| TWI757773B (zh) | 2019-06-28 | 2022-03-11 | 瑞士商愛爾康公司 | 眼用組成物 |
| CN114191378A (zh) * | 2021-11-23 | 2022-03-18 | 温州医科大学附属眼视光医院 | 一种地夸磷索缓释凝胶及其制备方法与应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09227385A (ja) * | 1996-02-29 | 1997-09-02 | Ofutekusu:Kk | 眼手術用補助剤 |
| CA2296080C (en) | 1997-07-29 | 2005-02-01 | Alcon Laboratories, Inc. | Ophthalmic compositions containing galactomannan polymers and borate |
| PT2116227E (pt) * | 2003-06-13 | 2013-06-28 | Novartis Ag | Composições oftálmicas que contêm uma combinação sinérgica de dois polímeros |
| US7947295B2 (en) * | 2003-06-13 | 2011-05-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| EP2109442B1 (en) * | 2007-02-09 | 2014-03-26 | Novartis AG | Ophthalmic compositions containing a synergistic combination of three polymers |
| US20090036554A1 (en) * | 2007-08-01 | 2009-02-05 | Burke Susan E | Ophthalmic compositions comprising a terpene compound |
| US9096819B2 (en) * | 2008-01-31 | 2015-08-04 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer |
| TWI526213B (zh) * | 2008-04-26 | 2016-03-21 | 愛爾康研究有限公司 | 聚合性人工淚液系統 |
| US20100087550A1 (en) * | 2008-10-06 | 2010-04-08 | Zora Marlowe | Formulations with a Tertiary Amine Oxide |
| KR20130060228A (ko) * | 2010-05-05 | 2013-06-07 | 알콘 리서치, 리미티드 | 안정화된 안과용 갈락토만난 제제 |
-
2013
- 2013-03-05 UA UAA201412705A patent/UA113434C2/uk unknown
- 2013-05-03 CN CN201811311427.8A patent/CN109157539A/zh active Pending
- 2013-05-03 AU AU2013256144A patent/AU2013256144B2/en active Active
- 2013-05-03 US US13/886,788 patent/US20130296264A1/en not_active Abandoned
- 2013-05-03 IN IN2248MUN2014 patent/IN2014MN02248A/en unknown
- 2013-05-03 CN CN201380031008.8A patent/CN104379131A/zh active Pending
- 2013-05-03 EP EP13723623.8A patent/EP2844226B1/en active Active
- 2013-05-03 PH PH1/2014/502571A patent/PH12014502571B1/en unknown
- 2013-05-03 PL PL13723623T patent/PL2844226T3/pl unknown
- 2013-05-03 BR BR112014027582-3A patent/BR112014027582B1/pt active IP Right Grant
- 2013-05-03 PT PT137236238T patent/PT2844226T/pt unknown
- 2013-05-03 ES ES13723623T patent/ES2761373T3/es active Active
- 2013-05-03 AR ARP130101515A patent/AR090930A1/es unknown
- 2013-05-03 WO PCT/US2013/039487 patent/WO2013166399A1/en active Application Filing
- 2013-05-03 KR KR1020147032805A patent/KR102076033B1/ko active Active
- 2013-05-03 RU RU2014148758A patent/RU2659207C2/ru active
- 2013-05-03 MX MX2014013444A patent/MX362266B/es active IP Right Grant
- 2013-05-03 CA CA2872622A patent/CA2872622C/en active Active
- 2013-05-03 DK DK13723623.8T patent/DK2844226T3/da active
-
2014
- 2014-11-19 ZA ZA2014/08490A patent/ZA201408490B/en unknown
-
2017
- 2017-02-01 US US15/421,513 patent/US20170136057A1/en not_active Abandoned
-
2019
- 2019-12-19 US US16/721,443 patent/US10828320B2/en active Active
-
2020
- 2020-10-01 US US17/060,343 patent/US11376275B2/en active Active
-
2022
- 2022-05-19 US US17/664,143 patent/US11672820B2/en active Active
-
2023
- 2023-05-17 US US18/319,196 patent/US20230285443A1/en active Pending
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