PH12014501704A1 - Method for preparing compound by novel michael addition reaction using water or various acids as additive - Google Patents

Method for preparing compound by novel michael addition reaction using water or various acids as additive

Info

Publication number
PH12014501704A1
PH12014501704A1 PH12014501704A PH12014501704A PH12014501704A1 PH 12014501704 A1 PH12014501704 A1 PH 12014501704A1 PH 12014501704 A PH12014501704 A PH 12014501704A PH 12014501704 A PH12014501704 A PH 12014501704A PH 12014501704 A1 PH12014501704 A1 PH 12014501704A1
Authority
PH
Philippines
Prior art keywords
additive
water
addition reaction
michael addition
various acids
Prior art date
Application number
PH12014501704A
Other languages
English (en)
Other versions
PH12014501704B1 (en
Inventor
Park Ae Ri
Kim Bong Chan
An Ji Eun
Lee Hee Bong
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of PH12014501704A1 publication Critical patent/PH12014501704A1/en
Publication of PH12014501704B1 publication Critical patent/PH12014501704B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58Preparation of carboxylic acid halides
    • C07C51/64Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/02Addition
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/62Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PH12014501704A 2012-02-03 2014-07-28 Method for preparing compound by novel michael addition reaction using water or various acids as additive PH12014501704B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120011317 2012-02-03
PCT/KR2013/000829 WO2013115595A1 (ko) 2012-02-03 2013-02-01 물 또는 다양한 산을 첨가제로 이용한 새로운 마이클-첨가 반응을 통하여 화합물을 제조하는 방법

Publications (2)

Publication Number Publication Date
PH12014501704A1 true PH12014501704A1 (en) 2014-10-13
PH12014501704B1 PH12014501704B1 (en) 2014-10-13

Family

ID=48905559

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12014501704A PH12014501704B1 (en) 2012-02-03 2014-07-28 Method for preparing compound by novel michael addition reaction using water or various acids as additive

Country Status (16)

Country Link
KR (1) KR101539761B1 (pt)
CN (1) CN104159884B (pt)
AU (1) AU2013215796B2 (pt)
BR (1) BR112014018985B1 (pt)
CL (1) CL2014002029A1 (pt)
CO (1) CO7030967A2 (pt)
EA (1) EA026411B1 (pt)
MA (1) MA35906B1 (pt)
MX (1) MX355336B (pt)
MY (1) MY168411A (pt)
PE (1) PE20142331A1 (pt)
PH (1) PH12014501704B1 (pt)
SG (1) SG11201404396TA (pt)
TN (1) TN2014000329A1 (pt)
WO (1) WO2013115595A1 (pt)
ZA (1) ZA201405598B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9774740B2 (en) 2008-01-28 2017-09-26 Afiniti Europe Technologies Limited Techniques for benchmarking pairing strategies in a contact center system

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108191647B (zh) * 2018-02-22 2020-09-29 江苏尚莱特医药化工材料有限公司 2,2-二氟二羧酸二烷基酯的合成方法
CN113149823B (zh) * 2021-03-29 2023-12-08 上海青平药业有限公司 一种2-r1戊酸的制备方法
CN113354495A (zh) * 2021-05-20 2021-09-07 上海应用技术大学 一种二氟酮羰基取代不对称腈类化合物及其制备与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS573159B2 (pt) * 1973-12-05 1982-01-20
ATE66469T1 (de) * 1985-01-14 1991-09-15 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
ES2299538T3 (es) * 2001-03-07 2008-06-01 Firmenich Sa Procedimiento para la preparacion de aductos de michael.
BRPI0819719B8 (pt) * 2007-12-21 2021-05-25 Lg Chemical Ltd compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativo

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9774740B2 (en) 2008-01-28 2017-09-26 Afiniti Europe Technologies Limited Techniques for benchmarking pairing strategies in a contact center system

Also Published As

Publication number Publication date
WO2013115595A1 (ko) 2013-08-08
AU2013215796A1 (en) 2014-08-21
CN104159884A (zh) 2014-11-19
SG11201404396TA (en) 2015-06-29
BR112014018985A2 (pt) 2017-06-20
BR112014018985A8 (pt) 2017-07-11
MY168411A (en) 2018-11-09
MA35906B1 (fr) 2014-12-01
CO7030967A2 (es) 2014-08-21
ZA201405598B (en) 2015-09-30
CN104159884B (zh) 2016-01-13
MX2014009309A (es) 2014-11-10
MX355336B (es) 2018-04-16
EA026411B1 (ru) 2017-04-28
AU2013215796B2 (en) 2016-09-15
PE20142331A1 (es) 2015-01-17
CL2014002029A1 (es) 2014-12-26
EA201491463A1 (ru) 2014-11-28
PH12014501704B1 (en) 2014-10-13
KR20130090360A (ko) 2013-08-13
KR101539761B1 (ko) 2015-07-28
TN2014000329A1 (en) 2015-12-21
BR112014018985B1 (pt) 2021-01-19

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