PH12014500397B1 - Use of the pacap as a molecular adjuvant for vaccines - Google Patents
Use of the pacap as a molecular adjuvant for vaccinesInfo
- Publication number
- PH12014500397B1 PH12014500397B1 PH1/2014/500397A PH12014500397A PH12014500397B1 PH 12014500397 B1 PH12014500397 B1 PH 12014500397B1 PH 12014500397 A PH12014500397 A PH 12014500397A PH 12014500397 B1 PH12014500397 B1 PH 12014500397B1
- Authority
- PH
- Philippines
- Prior art keywords
- pacap
- vaccines
- adjuvant
- aquatic organisms
- molecular adjuvant
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 239000002671 adjuvant Substances 0.000 title abstract 3
- 101150060255 MZB1 gene Proteins 0.000 title 1
- 101100462550 Mus musculus Adcyap1 gene Proteins 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- UDMBCSSLTHHNCD-KQYNXXCUSA-N adenosine 5'-monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 abstract 1
- 244000078703 ectoparasite Species 0.000 abstract 1
- 230000005745 host immune response Effects 0.000 abstract 1
- 238000007654 immersion Methods 0.000 abstract 1
- 239000012678 infectious agent Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001817 pituitary effect Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000004044 response Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0003—Invertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU2011000167A CU24075B1 (es) | 2011-08-26 | 2011-08-26 | Composición vacunal que comprende el péptido activador de la adenilato ciclasa de pituitaria como adyuvante molecular. |
| PCT/CU2012/000004 WO2013029570A1 (es) | 2011-08-26 | 2012-08-24 | Uso del pacap como adyuvante molecular para vacunas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PH12014500397A1 PH12014500397A1 (en) | 2014-04-14 |
| PH12014500397B1 true PH12014500397B1 (en) | 2018-09-12 |
Family
ID=47046313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH1/2014/500397A PH12014500397B1 (en) | 2011-08-26 | 2012-08-24 | Use of the pacap as a molecular adjuvant for vaccines |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9549977B2 (enExample) |
| EP (1) | EP2749291B1 (enExample) |
| JP (1) | JP6077541B2 (enExample) |
| KR (1) | KR101857705B1 (enExample) |
| CN (1) | CN103874510A (enExample) |
| AU (1) | AU2012303887B2 (enExample) |
| BR (1) | BR112014004620B1 (enExample) |
| CA (1) | CA2844898C (enExample) |
| CL (1) | CL2014000386A1 (enExample) |
| CU (1) | CU24075B1 (enExample) |
| ES (1) | ES2648337T3 (enExample) |
| MX (1) | MX351725B (enExample) |
| MY (1) | MY191697A (enExample) |
| NO (1) | NO2749291T3 (enExample) |
| PH (1) | PH12014500397B1 (enExample) |
| PT (1) | PT2749291T (enExample) |
| RU (1) | RU2580294C2 (enExample) |
| SG (1) | SG11201400215SA (enExample) |
| WO (1) | WO2013029570A1 (enExample) |
| ZA (1) | ZA201401271B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190060057A (ko) | 2017-11-24 | 2019-06-03 | 유병희 | 웰빙 무드등 |
| EP3970796B1 (en) * | 2019-05-14 | 2025-08-20 | Senju Pharmaceutical Co., Ltd. | Composition for preventing or treating neurotrophic keratitis which contains stabilized pacap peptide |
| CN117617183B (zh) * | 2023-11-29 | 2025-09-05 | 中国医学科学院医药生物技术研究所 | 突变体斑马鱼在制备凝血功能障碍疾病的动物模型中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE65568B1 (en) * | 1990-10-22 | 1995-11-01 | Unilever Plc | Vaccine compositions for fish |
| PE20010612A1 (es) * | 1999-09-28 | 2001-07-12 | Bayer Corp | Agonistas del receptor 3 (r3) del peptido activador de la adenilato ciclasa de la pituitaria y su uso farmacologico |
| GB0427267D0 (en) * | 2004-12-13 | 2005-01-12 | Maria Teresa De Magistris | Peptide adjuvants |
| CU23557A1 (es) | 2005-11-22 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Neuropéptidos para el cultivo de organismos acuáticos |
| CN102883739B (zh) * | 2009-11-02 | 2015-11-25 | 图兰恩教育基金管理人 | 垂体腺苷酸环化酶激活多肽（pacap）的类似物和它们的应用方法 |
| CN103255089B (zh) * | 2013-05-03 | 2015-08-05 | 中国水产科学研究院黄海水产研究所 | 一株强毒迟缓爱德华氏菌疫苗株及其应用 |
-
2011
- 2011-08-26 CU CU2011000167A patent/CU24075B1/es active IP Right Grant
-
2012
- 2012-08-24 JP JP2014526385A patent/JP6077541B2/ja active Active
- 2012-08-24 PH PH1/2014/500397A patent/PH12014500397B1/en unknown
- 2012-08-24 NO NO12775123A patent/NO2749291T3/no unknown
- 2012-08-24 US US14/238,377 patent/US9549977B2/en active Active
- 2012-08-24 CA CA2844898A patent/CA2844898C/en active Active
- 2012-08-24 CN CN201280041829.5A patent/CN103874510A/zh active Pending
- 2012-08-24 BR BR112014004620-4A patent/BR112014004620B1/pt active IP Right Grant
- 2012-08-24 ES ES12775123.8T patent/ES2648337T3/es active Active
- 2012-08-24 AU AU2012303887A patent/AU2012303887B2/en not_active Ceased
- 2012-08-24 MX MX2014002214A patent/MX351725B/es active IP Right Grant
- 2012-08-24 EP EP12775123.8A patent/EP2749291B1/en active Active
- 2012-08-24 SG SG11201400215SA patent/SG11201400215SA/en unknown
- 2012-08-24 KR KR1020147006186A patent/KR101857705B1/ko active Active
- 2012-08-24 WO PCT/CU2012/000004 patent/WO2013029570A1/es not_active Ceased
- 2012-08-24 MY MYPI2014700419A patent/MY191697A/en unknown
- 2012-08-24 RU RU2014111465/15A patent/RU2580294C2/ru active
- 2012-08-24 PT PT127751238T patent/PT2749291T/pt unknown
-
2014
- 2014-02-14 CL CL2014000386A patent/CL2014000386A1/es unknown
- 2014-02-19 ZA ZA2014/01271A patent/ZA201401271B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012303887B2 (en) | 2017-06-22 |
| KR20140064847A (ko) | 2014-05-28 |
| JP2014524450A (ja) | 2014-09-22 |
| PT2749291T (pt) | 2017-11-24 |
| CA2844898A1 (en) | 2013-03-07 |
| BR112014004620A2 (pt) | 2017-03-21 |
| CU24075B1 (es) | 2015-01-29 |
| EP2749291A1 (en) | 2014-07-02 |
| RU2014111465A (ru) | 2015-10-10 |
| MY191697A (en) | 2022-07-07 |
| CA2844898C (en) | 2021-06-22 |
| MX351725B (es) | 2017-10-25 |
| CU20110167A7 (es) | 2013-06-28 |
| ZA201401271B (en) | 2015-04-29 |
| US9549977B2 (en) | 2017-01-24 |
| US20140294889A1 (en) | 2014-10-02 |
| JP6077541B2 (ja) | 2017-02-08 |
| MX2014002214A (es) | 2014-04-30 |
| AU2012303887A1 (en) | 2014-03-06 |
| ES2648337T3 (es) | 2018-01-02 |
| RU2580294C2 (ru) | 2016-04-10 |
| BR112014004620B1 (pt) | 2019-10-29 |
| PH12014500397A1 (en) | 2014-04-14 |
| NO2749291T3 (enExample) | 2018-03-17 |
| KR101857705B1 (ko) | 2018-06-20 |
| CL2014000386A1 (es) | 2014-07-11 |
| CN103874510A (zh) | 2014-06-18 |
| EP2749291B1 (en) | 2017-10-18 |
| SG11201400215SA (en) | 2014-09-26 |
| WO2013029570A1 (es) | 2013-03-07 |
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