PE20221663A1 - Composicion para prevenir o tratar enfermedades pulmonares que comprende proteina 1 de union de hialuronano y proteoglucano - Google Patents
Composicion para prevenir o tratar enfermedades pulmonares que comprende proteina 1 de union de hialuronano y proteoglucanoInfo
- Publication number
- PE20221663A1 PE20221663A1 PE2022001520A PE2022001520A PE20221663A1 PE 20221663 A1 PE20221663 A1 PE 20221663A1 PE 2022001520 A PE2022001520 A PE 2022001520A PE 2022001520 A PE2022001520 A PE 2022001520A PE 20221663 A1 PE20221663 A1 PE 20221663A1
- Authority
- PE
- Peru
- Prior art keywords
- composition
- proteoglucan
- protein
- binding protein
- lung diseases
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 208000019693 Lung disease Diseases 0.000 title abstract 2
- KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 title abstract 2
- 229940099552 hyaluronan Drugs 0.000 title abstract 2
- 229920002674 hyaluronan Polymers 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 101001079904 Homo sapiens Hyaluronan and proteoglycan link protein 1 Proteins 0.000 abstract 4
- 102100028084 Hyaluronan and proteoglycan link protein 1 Human genes 0.000 abstract 3
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 2
- 206010006458 Bronchitis chronic Diseases 0.000 abstract 1
- 206010014561 Emphysema Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000007451 chronic bronchitis Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/314—Foods, ingredients or supplements having a functional effect on health having an effect on lung or respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Toxicology (AREA)
- Marine Sciences & Fisheries (AREA)
- Immunology (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE AL MENOS UNO SELECCIONADO DEL GRUPO QUE CONSISTE EN PROTEINA HAPLN1 (PROTEINA 1 DE UNION DE HIALURONANO Y PROTEOGLUCANO), UN GEN QUE CODIFICA LA PROTEINA HAPLN1 Y UN AGENTE EFICAZ PARA POTENCIAR LA EXPRESION O ACTIVAR LAS FUNCIONES DE LA PROTEINA O DEL GEN HAPLN1 COMO PRINCIPIO ACTIVO; DONDE LA PROTEINA HAPLN1 COMPRENDE UNA SECUENCIA DE AMINOACIDOS QUE TIENE AL MENOS UN 95 % DE IDENTIDAD DE SECUENCIA CON SEQ ID NO: 1. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE ENFERMEDADES PULMONARES COMO BRONQUITIS CRONICA, ASMA, ENFISEMA, ENFERMEDAD PULMONAR OBSTRUCTIVA CRONICA (EPOC).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020200012742A KR102166453B1 (ko) | 2020-02-03 | 2020-02-03 | Hapln1을 포함하는 폐질환 예방 또는 치료용 조성물 |
| PCT/KR2021/001374 WO2021158000A1 (en) | 2020-02-03 | 2021-02-02 | Composition for preventing or treating pulmonary diseases comprising hyaluronan and proteoglycan link protein 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20221663A1 true PE20221663A1 (es) | 2022-10-26 |
Family
ID=72882981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2022001520A PE20221663A1 (es) | 2020-02-03 | 2021-02-02 | Composicion para prevenir o tratar enfermedades pulmonares que comprende proteina 1 de union de hialuronano y proteoglucano |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US12268728B2 (es) |
| EP (1) | EP3887525B1 (es) |
| JP (1) | JP7329877B2 (es) |
| KR (1) | KR102166453B1 (es) |
| CN (1) | CN115427576B (es) |
| AR (1) | AR121243A1 (es) |
| AU (1) | AU2021216358A1 (es) |
| BR (1) | BR112022015361A2 (es) |
| CA (1) | CA3166146A1 (es) |
| CL (1) | CL2022002067A1 (es) |
| CO (1) | CO2022011135A2 (es) |
| ES (1) | ES2964715T3 (es) |
| IL (1) | IL294952A (es) |
| MX (1) | MX2022009544A (es) |
| PE (1) | PE20221663A1 (es) |
| TW (1) | TWI792171B (es) |
| WO (1) | WO2021158000A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102166453B1 (ko) | 2020-02-03 | 2020-10-15 | 중앙대학교 산학협력단 | Hapln1을 포함하는 폐질환 예방 또는 치료용 조성물 |
| KR102284800B1 (ko) | 2020-12-30 | 2021-08-03 | 주식회사 하플사이언스 | 재조합 세포외 기질 단백질의 생산을 위한 동물세포 배양용 배지 조성물 및 이를 이용한 방법 |
| KR102678583B1 (ko) * | 2021-05-31 | 2024-06-27 | 중앙대학교 산학협력단 | Hapln1을 포함하는 혈관질환 예방 또는 치료용 조성물 |
Family Cites Families (39)
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| JPS584462Y2 (ja) | 1980-10-13 | 1983-01-25 | 古賀産業株式会社 | 海苔「す」 |
| KR100785969B1 (ko) | 2004-05-12 | 2007-12-14 | 동아제약주식회사 | Fgf2를 유효성분으로 포함하는 천식 및 만성폐쇄성폐질환 예방 또는 치료제 |
| MX2007000625A (es) | 2004-07-16 | 2007-03-07 | Warner Lambert Co | Agentes activadores del crecimiento capilar. |
| GB0422525D0 (en) | 2004-10-11 | 2004-11-10 | Luebcke Peter | Dermatological compositions and methods |
| WO2007027509A2 (en) | 2005-08-31 | 2007-03-08 | Biogen Idec Ma Inc. | Evaluating and treating scleroderma |
| US7908090B2 (en) | 2005-11-30 | 2011-03-15 | The Board Of Trustees Of The Leland Stanford Junior University | Signatures for human aging |
| US20080139500A1 (en) | 2006-12-11 | 2008-06-12 | Isadore Elliott Goldberg | Use of composite monomer or monomers, catalyst, sodium hyaluronate or hyaluronic acid, glucosamide sulfate, chondroiten sulfate or chlorides, for the treatment of osteoarthritis by intraarticular application to a hip or knee joint |
| RU2631488C2 (ru) | 2009-07-10 | 2017-09-22 | Хистоджен, Инк. | Кондиционированная среда и композиции на основе внеклеточного матрикса из клеток, культивированных в гипоксических условиях |
| KR101704666B1 (ko) | 2009-07-16 | 2017-02-08 | 바이오타임, 인코포레이티드 | 시험관내 및 생체내 연골형성을 위한 방법 및 조성물 |
| US20120128632A1 (en) | 2009-07-23 | 2012-05-24 | Jeffrey Keeler Teumer | Identity markers |
| US8334136B2 (en) | 2009-07-24 | 2012-12-18 | Shiseido Company, Ltd. | Method for promoting hair growth or hair regeneration by maintaining or increasing expression of cell-adhesion factor |
| EP2552472A4 (en) | 2010-03-29 | 2014-03-12 | Massachusetts Inst Technology | INFLAMMATION INHIBITING FACTORS |
| EP2704728A4 (en) | 2011-05-03 | 2015-04-22 | Dermachip Inc | EXPRESSION SIGNATURES OF AGENTS ASSOCIATED WITH SKIN AGING AND GEN NETWORKS |
| JP6043343B2 (ja) | 2011-05-17 | 2016-12-14 | シャネル パフュームズ ビューテ | 皮膚の老化の予防および/もしくは低減ならびに/または皮膚を水和するためのlarge、hs6st2またはst8sia1活性化剤 |
| JP6162707B2 (ja) * | 2011-10-24 | 2017-07-12 | ハロザイム インコーポレイテッド | 抗ヒアルロナン剤治療のためのコンパニオン診断およびその使用方法 |
| JP5767591B2 (ja) | 2012-01-24 | 2015-08-19 | HOYA Technosurgical株式会社 | 人工軟骨の製造方法 |
| WO2013129456A1 (ja) | 2012-02-29 | 2013-09-06 | ロート製薬株式会社 | 線維芽細胞増殖促進能を有する組成物 |
| WO2013144672A1 (en) | 2012-03-30 | 2013-10-03 | Société De Développement Et De Recherche Industrielle | Method and kit for the classification and prognosis of wounds |
| EP2845910A4 (en) | 2012-05-02 | 2015-11-25 | Mitsubishi Rayon Co | PROBE OR PROBE TO EVALUATE THE INFLUENCE OF ULTRAVIOLET RADIATION ON SKIN AND NUCLEIC ACID MICRO ARRAYS |
| US10245229B2 (en) * | 2012-06-08 | 2019-04-02 | Translate Bio, Inc. | Pulmonary delivery of mRNA to non-lung target cells |
| JP2015528001A (ja) * | 2012-07-11 | 2015-09-24 | ティッシュテック,インク. | Hc−ha/ptx3複合体を含む組成物およびその使用方法 |
| AU2013237760A1 (en) | 2012-10-08 | 2014-04-24 | Biotime, Inc. | Differentiated progeny of clonal progenitor cell lines |
| WO2014130411A1 (en) | 2013-02-22 | 2014-08-28 | Emory University | Tgf-beta enhancing compositions for cartilage repair and methods related thereto |
| US20160192689A1 (en) | 2013-07-31 | 2016-07-07 | Wikifoods, Inc. | Encapsulated functional food compositions |
| US11819555B2 (en) | 2013-09-09 | 2023-11-21 | Figene, Llc | Gene therapy for the regeneration of chondrocytes or cartilage type cells |
| JP6538081B2 (ja) | 2014-07-07 | 2019-07-03 | メディポスト カンパニー リミテッド | 刺激を受けた幹細胞の馴化培地の発毛促進能およびそれらの使用 |
| HUE053684T2 (hu) | 2015-01-07 | 2021-07-28 | Pfizer | Oldható FGFR3 csalik csontnövekedési rendellenességek kezelésére |
| GB201505520D0 (en) | 2015-03-31 | 2015-05-13 | Univ Lancaster | Composition |
| KR101897340B1 (ko) * | 2015-09-09 | 2018-09-13 | 중앙대학교 산학협력단 | Hapln1을 이용한 피부 노화 측정 또는 예방 또는 개선용 조성물 |
| AU2017207445B2 (en) | 2016-01-14 | 2023-12-07 | Spinalcyte, Llc | Cellular blend for the regeneration of chondrocytes or cartilage type cells |
| KR101900748B1 (ko) | 2016-08-17 | 2018-09-20 | (주)진셀팜 | 모발 성장 촉진 효과를 가지는 펩타이드, 및 이의 용도 |
| CA3055168C (en) * | 2017-03-06 | 2022-09-06 | Haplnscience inc. | Composition for skin aging measurement, prevention, or alleviation using hapln1 |
| KR20190024727A (ko) | 2017-08-29 | 2019-03-08 | 중앙대학교 산학협력단 | Hapln1을 유효성분으로 함유하는 연골 재생용 조성물 |
| WO2019045451A1 (ko) | 2017-08-29 | 2019-03-07 | 중앙대학교 산학협력단 | Hapln1을 유효성분으로 함유하는 연골 재생용 조성물 |
| KR20200104831A (ko) | 2019-02-27 | 2020-09-04 | 주식회사 하플사이언스 | Hapln1을 포함하는 연골 관련 질환 또는 증상의 예방, 개선 또는 치료용 조성물 |
| MX2021008327A (es) | 2019-02-28 | 2021-08-11 | Haplnscience Inc | Composicion para prevenir, mejorar o tratar enfermedades o sintomas relacionados con el cartilago que comprende hapln1. |
| AU2020265476A1 (en) | 2019-04-30 | 2022-01-06 | Haplnscience inc. | Composition for prevention or treatment of hair loss including HAPLN1 |
| KR102166453B1 (ko) | 2020-02-03 | 2020-10-15 | 중앙대학교 산학협력단 | Hapln1을 포함하는 폐질환 예방 또는 치료용 조성물 |
| KR102284800B1 (ko) | 2020-12-30 | 2021-08-03 | 주식회사 하플사이언스 | 재조합 세포외 기질 단백질의 생산을 위한 동물세포 배양용 배지 조성물 및 이를 이용한 방법 |
-
2020
- 2020-02-03 KR KR1020200012742A patent/KR102166453B1/ko active Active
-
2021
- 2021-02-01 AR ARP210100261A patent/AR121243A1/es not_active Application Discontinuation
- 2021-02-02 BR BR112022015361A patent/BR112022015361A2/pt unknown
- 2021-02-02 JP JP2021521505A patent/JP7329877B2/ja active Active
- 2021-02-02 PE PE2022001520A patent/PE20221663A1/es unknown
- 2021-02-02 US US17/287,443 patent/US12268728B2/en active Active
- 2021-02-02 CA CA3166146A patent/CA3166146A1/en active Pending
- 2021-02-02 AU AU2021216358A patent/AU2021216358A1/en not_active Abandoned
- 2021-02-02 EP EP21717303.8A patent/EP3887525B1/en active Active
- 2021-02-02 ES ES21717303T patent/ES2964715T3/es active Active
- 2021-02-02 MX MX2022009544A patent/MX2022009544A/es unknown
- 2021-02-02 CN CN202180001405.5A patent/CN115427576B/zh active Active
- 2021-02-02 WO PCT/KR2021/001374 patent/WO2021158000A1/en not_active Ceased
- 2021-02-02 IL IL294952A patent/IL294952A/en unknown
- 2021-02-03 TW TW110104089A patent/TWI792171B/zh active
-
2022
- 2022-08-01 CL CL2022002067A patent/CL2022002067A1/es unknown
- 2022-08-05 CO CONC2022/0011135A patent/CO2022011135A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022524899A (ja) | 2022-05-11 |
| AU2021216358A1 (en) | 2022-09-01 |
| MX2022009544A (es) | 2022-08-25 |
| CA3166146A1 (en) | 2021-08-12 |
| BR112022015361A2 (pt) | 2022-09-20 |
| CN115427576B (zh) | 2025-02-28 |
| US20220305077A1 (en) | 2022-09-29 |
| IL294952A (en) | 2022-09-01 |
| CN115427576A (zh) | 2022-12-02 |
| EP3887525A4 (en) | 2022-06-22 |
| WO2021158000A1 (en) | 2021-08-12 |
| EP3887525A1 (en) | 2021-10-06 |
| TWI792171B (zh) | 2023-02-11 |
| EP3887525B1 (en) | 2023-08-23 |
| ES2964715T3 (es) | 2024-04-09 |
| JP7329877B2 (ja) | 2023-08-21 |
| AR121243A1 (es) | 2022-05-04 |
| TW202130360A (zh) | 2021-08-16 |
| CL2022002067A1 (es) | 2023-01-20 |
| US12268728B2 (en) | 2025-04-08 |
| EP3887525C0 (en) | 2023-08-23 |
| CO2022011135A2 (es) | 2022-08-30 |
| KR102166453B1 (ko) | 2020-10-15 |
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