PE20211750A1 - Sintesis de 5-cloro-2-[(3,4,4-trifluoro-3-buten-1-il)tio]-tiazol - Google Patents

Sintesis de 5-cloro-2-[(3,4,4-trifluoro-3-buten-1-il)tio]-tiazol

Info

Publication number
PE20211750A1
PE20211750A1 PE2020000992A PE2020000992A PE20211750A1 PE 20211750 A1 PE20211750 A1 PE 20211750A1 PE 2020000992 A PE2020000992 A PE 2020000992A PE 2020000992 A PE2020000992 A PE 2020000992A PE 20211750 A1 PE20211750 A1 PE 20211750A1
Authority
PE
Peru
Prior art keywords
formula
weight
ncs
buten
trifluoro
Prior art date
Application number
PE2020000992A
Other languages
English (en)
Inventor
Boris Rubinov
Thomas Zell
Original Assignee
Adama Makhteshim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adama Makhteshim Ltd filed Critical Adama Makhteshim Ltd
Publication of PE20211750A1 publication Critical patent/PE20211750A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Abstract

La presente invencion se refiere a un procedimiento para la preparacion de 5-cloro-2-[3,4,4-trifluoro-3-buten-1-il)tio]-tiazol de formula (I). Este proceso comprende hacer reaccionar 2-[3,4,4-trifluoro-3-buten-1-il)tio]-tiazol de formula (II) con N-clorosuccinimida (NCS) en presencia de una cantidad reducida de agua, donde: i) concentracion de agua entre el 0% en peso y el 5% en peso en relacion con el peso total de la mezcla de reaccion; ii) concentracion de agua entre el 0% en peso y el 7% en peso en relacion con el peso del compuesto de formula (II) en la mezcla de reaccion; iii) concentracion de agua entre 0% en peso y el 7% en peso en relacion con el peso de NCS en la mezcla de reaccion. Tambien se refiere a un procedimiento mejorado para la preparacion de 5-cloro-2-[3,4,4-trifluoro-3-buten-1-il)tio]-tiazol de formula (I) que comprende hacer reaccionar 2-[3,4,4-trifluoro-3-buten-1-il)tio]-tiazol de formula (II) con N-clorosuccinimida (NCS) en presencia de agua y con una cantidad molar en exceso de NCS, donde la relacion molar de NCS con respecto al compuesto de formula (II) es de aproximadamente 3:1 hasta aproximadamente 1:8,5. Tambien se refiere a un procedimiento para la preparacion de un compuesto de formula (III) que comprende convertir el compuesto de formula (I) con NCS segun el procedimiento. El compuesto de formula (I) corresponde a un principio activo muy eficaz contra nematodos parasitos de plantas.
PE2020000992A 2018-01-23 2019-01-22 Sintesis de 5-cloro-2-[(3,4,4-trifluoro-3-buten-1-il)tio]-tiazol PE20211750A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862620769P 2018-01-23 2018-01-23
PCT/IB2019/050533 WO2019145857A2 (en) 2018-01-23 2019-01-22 Synthesis of 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)thio]-thiazole

Publications (1)

Publication Number Publication Date
PE20211750A1 true PE20211750A1 (es) 2021-09-06

Family

ID=67395259

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2020000992A PE20211750A1 (es) 2018-01-23 2019-01-22 Sintesis de 5-cloro-2-[(3,4,4-trifluoro-3-buten-1-il)tio]-tiazol

Country Status (10)

Country Link
US (1) US11352335B2 (es)
CN (1) CN111885917B (es)
AR (1) AR114185A1 (es)
AU (1) AU2019212442A1 (es)
BR (1) BR112020015004A2 (es)
CA (1) CA3089436A1 (es)
IL (1) IL276196B2 (es)
MX (1) MX2020007630A (es)
PE (1) PE20211750A1 (es)
WO (1) WO2019145857A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR122022001869B1 (pt) 2015-12-10 2022-09-13 Adama Makhteshim Ltd. Composição de material agrícola, método de controle e prevenção de peste e de aperfeiçoamento do crescimento de planta, processo de preparo da composição de material agrícola e uso de um copolímero em bloco
AR114185A1 (es) 2018-01-23 2020-07-29 Adama Makhteshim Ltd Síntesis de 5-cloro-2-[(3,4,4-trifluoro-3-buten-1-il)tio]-tiazol

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007731A3 (en) 1978-07-28 1980-02-20 Imperial Chemical Industries Plc Process for the production of dispersions of hydrophobic particulate solids (e.g. pesticides) and the particulate dispersions thus obtained
US5085698A (en) 1990-04-11 1992-02-04 E. I. Du Pont De Nemours And Company Aqueous pigmented inks for ink jet printers
US5763548A (en) 1995-03-31 1998-06-09 Carnegie-Mellon University (Co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization
ATE271043T1 (de) * 1995-12-21 2004-07-15 Syngenta Participations Ag Verfahren zur herstellung von 2-chlor-5- chloromethyl-thiazol
DE19621983A1 (de) 1996-06-03 1997-12-04 Basf Ag Verwendung von Copolymeren aus hydrophilen und hydrophoben Monomeren zur Erhöhung der Lösegeschwindigkeit von teilchenförmigen Waschmittelformulierungen in Wasser
DE69709110T2 (de) 1996-07-10 2002-04-25 Du Pont Polymerisation mit "living" kennzeichen
US5708095A (en) 1996-08-30 1998-01-13 E. I. Du Pont De Nemours And Company Graft copolymers containing sulfonate and phosphonate groups having particular utility as pigmented ink dispersants
FR2764892B1 (fr) 1997-06-23 2000-03-03 Rhodia Chimie Sa Procede de synthese de polymeres a blocs
JP2001510208A (ja) 1997-07-15 2001-07-31 チバ スペシャルティ ケミカルズ ホールディング インコーポレーテッド ニトロソ化合物又はニトロン化合物から誘導されたアルコキシアミン化合物を含む重合可能な組成物
KR100589073B1 (ko) 1997-12-18 2006-06-13 이 아이 듀폰 디 네모아 앤드 캄파니 리빙 특성의 중합 방법 및 이 방법으로 제조된 중합체
FR2773161B1 (fr) 1997-12-31 2000-01-21 Rhodia Chimie Sa Procede de synthese de polymeres a blocs
US6812291B1 (en) 1997-12-31 2004-11-02 Rhodia Chimie Method for block polymer synthesis by controlled radical polymerization from dithiocarbamate compounds
US6262152B1 (en) 1998-10-06 2001-07-17 E. I. Du Pont De Nemours And Company Particles dispersed w/polymer dispersant having liquid soluble and cross-linkable insoluble segments
US6204319B1 (en) 1998-10-30 2001-03-20 E.I. Du Pont De Nemours And Company Aqueous coating compositions
FR2794463B1 (fr) 1999-06-04 2005-02-25 Rhodia Chimie Sa Procede de synthese de polymeres par polymerisation radicalaire controlee a l'aide de xanthates halogenes
JP2001019685A (ja) 1999-07-06 2001-01-23 Nippon Bayer Agrochem Co Ltd 殺センチュウ性トリフルオロブテン類
JP2001322988A (ja) 2000-03-09 2001-11-20 Nippon Bayer Agrochem Co Ltd 殺センチュウ性トリフルオロブテン類
AT408756B (de) * 2000-05-23 2002-03-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von 2-chlor-5-chlormethyl-1,3-thiazol
DE10034130A1 (de) 2000-07-13 2002-01-24 Bayer Ag Heterocyclische Fluoralkenylthioether (lV)
FR2812293B1 (fr) 2000-07-28 2002-12-27 Rhodia Chimie Sa Procede de synthese de polymeres a blocs par polymerisation radicalaire controlee
AU2001290979A1 (en) 2000-09-14 2002-03-26 Rohm And Haas Company A method of improving the melt processing of thermoplastic polymers and compositions produced thereby
FR2814168B1 (fr) 2000-09-18 2006-11-17 Rhodia Chimie Sa Procede de synthese de polymeres a blocs par polymerisation radicalaire controlee en presence d'un compose disulfure
US6569969B2 (en) 2000-09-28 2003-05-27 Symyx Technologies, Inc. Control agents for living-type free radical polymerization, methods of polymerizing and polymers with same
US6579947B2 (en) 2001-02-20 2003-06-17 Rhodia Chimie Hydraulic fracturing fluid comprising a block copolymer containing at least one water-soluble block and one hydrophobic block
JP2003113168A (ja) * 2001-09-28 2003-04-18 Bayer Ag 殺センチュウ性トリフルオロブテン誘導体
DE10229776A1 (de) * 2002-07-03 2004-01-22 Bayer Cropscience Ag Verfahren zum Herstellen von heterocyclischen Fluoralkenylsulfonen
DE10319591A1 (de) 2003-05-02 2004-11-18 Bayer Cropscience Ag Wirkstoffkombinationen mit nematiziden, insektiziden und fungiziden Eigenschaften basierend auf Trifluorbutenyl-Verbindungen
DE10319590A1 (de) 2003-05-02 2004-11-18 Bayer Cropscience Ag Wirkstoffkombinationen mit nematiziden und insektiziden Eigenschaften basierend auf Trifluorbutenyl-Verbindungen
US7576216B2 (en) * 2004-07-30 2009-08-18 Abbott Laboratories Preparation of pyridonecarboxylic acid antibacterials
AU2006233601A1 (en) 2005-04-08 2006-10-19 Syngenta Participations Ag. Method of mollusc control
EP1973400A2 (en) 2006-01-10 2008-10-01 Innovaform Technologies, LLC Pesticide delivery system
US20070194216A1 (en) 2006-02-21 2007-08-23 Exatec, Llc Printable controls for a window assembly
MX2009006321A (es) 2006-12-13 2009-06-30 Innovaform Technologies Llc Agregados de pesticidas.
CN105309424B (zh) 2008-09-25 2022-09-02 维乌作物保护有限公司 生产聚合物纳米颗粒的方法和活性成分的制剂
CN102209468A (zh) 2008-11-07 2011-10-05 巴斯夫欧洲公司 具有三种溶剂的农业化学配制剂
BR112012003069B1 (pt) 2009-08-14 2018-05-22 Bayer Intellectual Property Gmbh Concentrados de suspensão de metribuzina, de alta concentração, sem silicato de alumínio.
CA2802787C (en) 2010-06-18 2020-02-25 Bayer Intellectual Property Gmbh Active substance combinations with insecticide and acaricide properties
DE102011014354A1 (de) 2011-03-17 2012-09-20 Clariant International Ltd. Suspensionskonzentrate
GB201111439D0 (en) 2011-07-04 2011-08-17 Syngenta Ltd Formulation
WO2013093578A1 (en) 2011-12-22 2013-06-27 Vive Crop Protection Inc. Strobilurin formulations
EP3476219B1 (en) 2012-01-17 2023-08-30 Syngenta Participations AG Pesticidal mixtures including spiroheterocyclic pyrrolidine diones
EP2836073A1 (en) 2012-03-05 2015-02-18 Ceradis B.V. Polyelectrolyte complexes for biocide enhancement
US9961900B2 (en) 2012-06-11 2018-05-08 Vive Crop Protection Inc. Herbicide formulations
EP2863953A1 (de) 2012-06-22 2015-04-29 Basf Se Wirkstoffhaltige festen dispersionen auf basis von diethylaminoethylmethacrylat-copolymeren
WO2014002111A1 (en) * 2012-06-26 2014-01-03 Rallis India Limited Process of preparation of azimsulfuron
FR3011555A1 (fr) 2013-10-04 2015-04-10 Rhodia Operations Polymeres sequences pour le controle du filtrat
EP3099167A4 (en) 2014-01-29 2017-09-06 Verdesian Life Siciences, LLC Adjuvants for plant growth regulators
CN104982431A (zh) 2015-06-09 2015-10-21 天津市华宇农药有限公司 一种含有异丙草胺和莠去津的除草剂组合物及其制备方法
AR114185A1 (es) 2018-01-23 2020-07-29 Adama Makhteshim Ltd Síntesis de 5-cloro-2-[(3,4,4-trifluoro-3-buten-1-il)tio]-tiazol

Also Published As

Publication number Publication date
US11352335B2 (en) 2022-06-07
WO2019145857A3 (en) 2019-09-26
IL276196A (en) 2020-09-30
BR112020015004A2 (pt) 2020-12-29
US20210070719A1 (en) 2021-03-11
IL276196B1 (en) 2023-09-01
CN111885917B (zh) 2023-07-28
CN111885917A (zh) 2020-11-03
WO2019145857A2 (en) 2019-08-01
IL276196B2 (en) 2024-01-01
MX2020007630A (es) 2020-09-14
AR114185A1 (es) 2020-07-29
AU2019212442A1 (en) 2020-08-06
CA3089436A1 (en) 2019-08-01

Similar Documents

Publication Publication Date Title
PE20211750A1 (es) Sintesis de 5-cloro-2-[(3,4,4-trifluoro-3-buten-1-il)tio]-tiazol
HN2011000699A (es) El compuesto (s)-1-({4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il}-amida) de 2-amida del acido pirrolidin-1,2-dicarboxilico en forma libre o de sal y composiciones y composicion farmaceutica que lo contiene.
MA33364B1 (fr) Dérivés aminobutyriques substitués en tant qu'inhibiteurs de néprilysine
AR074696A1 (es) Derivados heterociclicos de isoxazol para su uso como reguladores del crecimiento de plantas.
BRPI0817096B8 (pt) análogo de tiazolidinodiona e composição farmacêutica que o compreende
AR089372A1 (es) Composiciones de cuidado oral
EA200801828A2 (ru) Соединения 1,2,4,5-тетрагидро-3h-бензазепина, способ их получения и фармацевтические композиции, содержащие эти соединения
AR099134A1 (es) Procedimiento para la preparación de n-[(3-aminooxetán-3-il)metil]-2-(1,1-dioxo-3,5-dihidro-1,4-benzotiazepín-4-il)-6-metil-quinazolín-4-amina
CO6400227A2 (es) Análogos de nucleosidos
AR087470A1 (es) Derivados imidazolicos bifenilenicos y composiciones farmaceuticas que los contienen
DK2190426T3 (da) Griseofulvin-analoger til behandling af cancer ved hæmning af centrosomal clusterdannelse
PE20230322A1 (es) Aminotiazoles sustituidos como inhibidores de dgkzeta para la activacion inmune
AR078318A1 (es) Compuestos carbonatos de anti-biopelicula para su uso en composiciones de cuidado oral
AR076181A1 (es) Compuestos derivados de mentol y uso de los mismos como agentes activos orales y sistemicos. metodo. composicion.
BR112012027383A2 (pt) composição para o controle de doenças de plantas e uso da mesma
AR089409A1 (es) Agente de control de enfermedades de las plantas
BRPI0508232A (pt) sìntese de epotilonas, intermediários das mesmas, análogos e usos das mesmas
CL2021000109A1 (es) Compuestos de isoxazolina para controlar plagas de invertebrados
AR087346A1 (es) Formulaciones de compuestos de tiofeno
CO6612211A2 (es) Derivado de amida que tiene una acción hipoglucémica y/o una acción protectora de células b o pancreas
BRPI1014887A8 (pt) composição farmacêutica para uso no tratamento de neoplasias e uso de um composto provendo di-hidroartemesinina via dosagem sublingual, transmucosal, bucal ou nasal
MX2021007335A (es) Forma amorfa y proceso.
AR066054A1 (es) Proceso para preparar galantamina
CY1112146T1 (el) Βακτηριοκτονος συνθεση για αγροτικη ή κηπουρικη χρηση και μεθοδος ελεγχου ασθενειας φυτου
MX2020004842A (es) Compuestos heterociclicos antiinfecciosos y sus usos.