BRPI1014887A8 - composição farmacêutica para uso no tratamento de neoplasias e uso de um composto provendo di-hidroartemesinina via dosagem sublingual, transmucosal, bucal ou nasal - Google Patents
composição farmacêutica para uso no tratamento de neoplasias e uso de um composto provendo di-hidroartemesinina via dosagem sublingual, transmucosal, bucal ou nasalInfo
- Publication number
- BRPI1014887A8 BRPI1014887A8 BRPI1014887A BRPI1014887A BRPI1014887A8 BR PI1014887 A8 BRPI1014887 A8 BR PI1014887A8 BR PI1014887 A BRPI1014887 A BR PI1014887A BR PI1014887 A BRPI1014887 A BR PI1014887A BR PI1014887 A8 BRPI1014887 A8 BR PI1014887A8
- Authority
- BR
- Brazil
- Prior art keywords
- buccal
- transmucosal
- pharmaceutical composition
- nasal dosage
- sublingual
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
"composição farmacêutica para uso no tratamento de neoplasias e uso de um composto proven- do di-hidroartemesinina via dosagem sublingual, trans- mucosal, bucal ou nasal". a presente invenção refere-se a composições farmacêuticas para o tratamento de doenças neoplásicas, infestações por chistossoma e doença de lyme, que inclui compostos capazes de prover dihidroartemesin!na e triglicerídeos de cadeia média formulados para entregua transmucosal sublingual, bucal ou nasal, especialmente por um spray. também são providos dispositivos de aplicação contendo as composições.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/GB2009/050415 WO2010122275A1 (en) | 2009-04-23 | 2009-04-23 | Pharmaceutical preparation |
GB0906971.7A GB2469791B (en) | 2009-04-23 | 2009-04-23 | Transmucosal formulation of compounds providing dihydroartemesinin for use in the treatment of neoplastic disease |
PCT/GB2010/050672 WO2010122356A1 (en) | 2009-04-23 | 2010-04-23 | Sublingual spray formulation comprising dihydroartemesinin |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI1014887A2 BRPI1014887A2 (pt) | 2016-04-19 |
BRPI1014887A8 true BRPI1014887A8 (pt) | 2019-02-12 |
Family
ID=42244197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1014887A BRPI1014887A8 (pt) | 2009-04-23 | 2010-04-23 | composição farmacêutica para uso no tratamento de neoplasias e uso de um composto provendo di-hidroartemesinina via dosagem sublingual, transmucosal, bucal ou nasal |
Country Status (24)
Country | Link |
---|---|
US (4) | US20120157518A1 (pt) |
EP (1) | EP2424523B1 (pt) |
JP (1) | JP5795760B2 (pt) |
CN (1) | CN102395362B (pt) |
AU (1) | AU2010240654C1 (pt) |
BR (1) | BRPI1014887A8 (pt) |
CA (1) | CA2756925A1 (pt) |
DK (1) | DK2424523T3 (pt) |
ES (1) | ES2390046T3 (pt) |
HK (1) | HK1164140A1 (pt) |
HR (1) | HRP20120711T1 (pt) |
IL (1) | IL215453A (pt) |
ME (1) | ME02008B (pt) |
MX (1) | MX2011010961A (pt) |
MY (1) | MY155646A (pt) |
NZ (1) | NZ595469A (pt) |
PL (1) | PL2424523T3 (pt) |
PT (1) | PT2424523E (pt) |
RS (1) | RS52430B (pt) |
RU (1) | RU2501550C2 (pt) |
SG (1) | SG175162A1 (pt) |
SI (1) | SI2424523T1 (pt) |
WO (1) | WO2010122356A1 (pt) |
ZA (1) | ZA201107088B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0720967D0 (en) * | 2007-10-25 | 2007-12-05 | Protophama Ltd | Anti-material pharmaceutical composition |
CN102458358A (zh) * | 2009-04-23 | 2012-05-16 | 伦敦制药有限公司 | 包含中性油的舌下药学组合物 |
AU2014204733B2 (en) * | 2013-01-14 | 2016-09-08 | Clinics Operations Limited | Cancer drug and uses |
US20170326102A1 (en) | 2014-11-27 | 2017-11-16 | Cipla Limited | Pharmaceutical Composition Comprising an Artemisinin Derivative for Nasal or Pulmonary Delivery |
JP2020033304A (ja) * | 2018-08-30 | 2020-03-05 | 医療法人ふじいやさか | 薬剤又はサプリメント、組成物、及び水素供給器の使用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
CH692321A5 (de) * | 1997-11-03 | 2002-05-15 | Mepha Ag | Pharmazeutisch wirksame Zusammensetzung, welche eine gegen Malariaparasiten wirksame Substanz enthält. |
EP1095042B9 (en) * | 1998-07-14 | 2006-07-05 | Bayer HealthCare AG | Antiparasitic artemisinin derivatives (endoperoxides) |
EP1351678A2 (en) * | 2001-01-02 | 2003-10-15 | Elizabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens |
WO2003101357A1 (en) * | 2002-05-31 | 2003-12-11 | University Of Mississippi | Transmucosal delivery of cannabinoids |
CN101843904A (zh) * | 2002-06-06 | 2010-09-29 | 华盛顿大学 | 使用青蒿素样化合物预防或延缓癌症显现的方法 |
WO2004075921A1 (en) * | 2003-02-26 | 2004-09-10 | Vrije Universiteit Brussel | Inclusion complex of artemisinin or derivates thereof with cyclodextrins |
US20060084675A1 (en) * | 2004-10-18 | 2006-04-20 | Thomas Efferth | Combined treatment with artesunate and an epidermal growth factor receptor kinase inhibitor |
US20060233895A1 (en) * | 2005-04-15 | 2006-10-19 | Brown Paul R | Herbal remedy for treating Lyme disease |
PL1933809T3 (pl) * | 2005-10-11 | 2012-09-28 | Yissum Research Development Company Of The Hebrew Univ Of Jerusalem | Kompozycje do dostarczania donosowego |
CN100418524C (zh) * | 2005-10-26 | 2008-09-17 | 重庆医药工业研究院有限责任公司 | 一种稳定的青蒿素及青蒿素衍生物的药物组合物 |
-
2010
- 2010-04-23 CN CN201080017965.1A patent/CN102395362B/zh not_active Expired - Fee Related
- 2010-04-23 PL PL10715337T patent/PL2424523T3/pl unknown
- 2010-04-23 SI SI201030076T patent/SI2424523T1/sl unknown
- 2010-04-23 EP EP10715337A patent/EP2424523B1/en active Active
- 2010-04-23 MY MYPI2011005080A patent/MY155646A/en unknown
- 2010-04-23 SG SG2011073954A patent/SG175162A1/en unknown
- 2010-04-23 ES ES10715337T patent/ES2390046T3/es active Active
- 2010-04-23 MX MX2011010961A patent/MX2011010961A/es active IP Right Grant
- 2010-04-23 RS RS20120393A patent/RS52430B/en unknown
- 2010-04-23 RU RU2011139637/15A patent/RU2501550C2/ru active
- 2010-04-23 AU AU2010240654A patent/AU2010240654C1/en not_active Ceased
- 2010-04-23 PT PT10715337T patent/PT2424523E/pt unknown
- 2010-04-23 NZ NZ595469A patent/NZ595469A/xx not_active IP Right Cessation
- 2010-04-23 WO PCT/GB2010/050672 patent/WO2010122356A1/en active Application Filing
- 2010-04-23 ME MEP-2012-393A patent/ME02008B/me unknown
- 2010-04-23 JP JP2012506584A patent/JP5795760B2/ja not_active Expired - Fee Related
- 2010-04-23 DK DK10715337.1T patent/DK2424523T3/da active
- 2010-04-23 CA CA2756925A patent/CA2756925A1/en not_active Abandoned
- 2010-04-23 BR BRPI1014887A patent/BRPI1014887A8/pt not_active Application Discontinuation
- 2010-04-23 US US13/265,518 patent/US20120157518A1/en not_active Abandoned
-
2011
- 2011-09-28 ZA ZA2011/07088A patent/ZA201107088B/en unknown
- 2011-10-02 IL IL215453A patent/IL215453A/en active IP Right Grant
-
2012
- 2012-05-18 HK HK12104912.3A patent/HK1164140A1/xx not_active IP Right Cessation
- 2012-09-06 HR HRP20120711AT patent/HRP20120711T1/hr unknown
-
2015
- 2015-07-30 US US14/813,424 patent/US20160022629A1/en not_active Abandoned
-
2017
- 2017-09-06 US US15/697,240 patent/US20170368023A1/en not_active Abandoned
-
2018
- 2018-10-18 US US16/164,610 patent/US20190142737A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |