PE20200336A1 - Formulaciones a largo plazo - Google Patents

Formulaciones a largo plazo

Info

Publication number
PE20200336A1
PE20200336A1 PE2020000033A PE2020000033A PE20200336A1 PE 20200336 A1 PE20200336 A1 PE 20200336A1 PE 2020000033 A PE2020000033 A PE 2020000033A PE 2020000033 A PE2020000033 A PE 2020000033A PE 20200336 A1 PE20200336 A1 PE 20200336A1
Authority
PE
Peru
Prior art keywords
long
pharmaceutical compositions
term formulations
formulations
term
Prior art date
Application number
PE2020000033A
Other languages
English (en)
Spanish (es)
Inventor
Koenraad Jozef Lodewijk Marcel Andries
Maristella Bernini
Esther Dina Guido Basstanie
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PE20200336A1 publication Critical patent/PE20200336A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PE2020000033A 2017-07-14 2018-07-13 Formulaciones a largo plazo PE20200336A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17181354 2017-07-14
EP18167463 2018-04-16
PCT/EP2018/069066 WO2019012100A1 (en) 2017-07-14 2018-07-13 EXTENDED ACTION FORMULATIONS

Publications (1)

Publication Number Publication Date
PE20200336A1 true PE20200336A1 (es) 2020-02-14

Family

ID=62874924

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2020000033A PE20200336A1 (es) 2017-07-14 2018-07-13 Formulaciones a largo plazo

Country Status (28)

Country Link
US (2) US11141384B2 (enExample)
EP (3) EP3651736B1 (enExample)
JP (3) JP7102500B2 (enExample)
KR (2) KR20240108542A (enExample)
CN (2) CN110869004B (enExample)
AU (1) AU2018298855B2 (enExample)
BR (1) BR112020000687A2 (enExample)
CO (1) CO2020000328A2 (enExample)
CY (1) CY1124782T1 (enExample)
DK (2) DK3943070T3 (enExample)
ES (2) ES2970801T3 (enExample)
FI (1) FI3943070T3 (enExample)
HR (2) HRP20240058T1 (enExample)
HU (2) HUE064651T2 (enExample)
JO (1) JOP20200004B1 (enExample)
LT (2) LT3651736T (enExample)
MD (1) MD3651736T2 (enExample)
MX (1) MX393782B (enExample)
PE (1) PE20200336A1 (enExample)
PH (1) PH12020500076A1 (enExample)
PL (2) PL3651736T3 (enExample)
RS (2) RS62362B1 (enExample)
SA (1) SA520410975B1 (enExample)
SI (2) SI3943070T1 (enExample)
SM (2) SMT202400033T1 (enExample)
UA (1) UA126403C2 (enExample)
WO (1) WO2019012100A1 (enExample)
ZA (1) ZA202000215B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3651736B1 (en) 2017-07-14 2021-06-23 Janssen Pharmaceutica NV Long-acting formulations
US20220023282A1 (en) * 2018-12-13 2022-01-27 Mannkind Corporation Compositions of Bedaquiline, Combinations Comprising Them, Processes for Their Preparation, Uses and Methods of Treatment Comprising Them
WO2022008645A1 (en) 2020-07-09 2022-01-13 Janssen Pharmaceutica Nv Long-acting formulations
US20240277614A1 (en) 2020-07-09 2024-08-22 Janssen Pharmaceutica Nv Long-acting formulations
AU2021303490A1 (en) 2020-07-09 2023-03-09 Janssen Pharmaceutica Nv Long-acting formulations
US20230346770A1 (en) * 2020-11-12 2023-11-02 Janssen Pharmaceutica Nv Combination of bedaquiline, ethambutol and a macrolide in the treatment of nontuberculous mycobacterial diseases
US11793808B2 (en) 2021-02-22 2023-10-24 Mannkind Corp. Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them
WO2024068693A1 (en) 2022-09-28 2024-04-04 Janssen Pharmaceutica Nv Long-acting formulations
CA3268292A1 (en) 2022-09-28 2024-04-04 Janssen Pharmaceutica Nv LONG-ACTING FORMULAS

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5346702A (en) 1992-12-04 1994-09-13 Sterling Winthrop Inc. Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization
US5352459A (en) 1992-12-16 1994-10-04 Sterling Winthrop Inc. Use of purified surface modifiers to prevent particle aggregation during sterilization
US6495534B2 (en) 2000-05-15 2002-12-17 Pharmacia & Upjohn Spa Stabilized aqueous suspensions for parenteral use
RS52431B (sr) 2002-07-25 2013-02-28 Janssen Pharmaceutica N.V. Derivati hinolina i njihova upotreba kao mikobakterijskih inhibitora
EE05394B1 (et) 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis
KR101534021B1 (ko) 2005-05-25 2015-07-06 얀센 파마슈티카 엔.브이. (알파 s, 베타 r)-6-브로모-알파-(2-(디메틸아미노)에틸)-2-메톡시-알파-1-나프탈레닐-베타-페닐-3-퀴놀린에탄올의 제조 방법
AP2618A (en) 2006-06-23 2013-03-18 Tibotec Pharmaceutical Ltd Aqueous suspensions of TMC278
UA97813C2 (uk) 2006-12-05 2012-03-26 Янссен Фармацевтика Н.В. Фумаратна сіль (альфа s, бета r)-6-бром-альфа-[2-(диметиламіно)етил]-2-метоксі-альфа-1-нафталеніл-бета-феніл-3-хінолінетанолу
TW201023912A (en) 2008-12-05 2010-07-01 Alcon Res Ltd Pharmaceutical suspension
US9421194B2 (en) 2010-04-05 2016-08-23 Rutgers, The State University Of New Jersey Lung targeting dual drug delivery system
TWI577377B (zh) 2010-09-16 2017-04-11 Viiv醫療保健公司 醫藥組合物
ES2823805T3 (es) 2011-04-15 2021-05-10 Janssen Pharmaceutica Nv Nanosuspensiones de fármacos secadas por congelamiento
JP2017523207A (ja) 2014-08-08 2017-08-17 ファーマサイクリックス エルエルシー ブルトン型チロシンキナーゼ阻害薬の組み合わせ及びそれらの使用
AU2016212116B2 (en) * 2015-01-27 2021-07-15 Janssen Pharmaceutica Nv Dispersible compositions
WO2016179231A1 (en) * 2015-05-04 2016-11-10 Board Of Trustees Of Michigan State University Compositions and methods for inhibiting bacterial growth
HK1254620A1 (zh) 2015-10-14 2019-07-26 结核病药物开发全球联盟公司 联合抗菌组合物以及短疗程抗菌方案
CN108349898B (zh) * 2015-10-20 2021-03-23 浙江海正药业股份有限公司 富马酸贝达喹啉的晶型及其制备方法
US20200179273A1 (en) 2017-06-06 2020-06-11 Merck Sharp & DohmeCorp Long-action implant for treatment of infectious diseases
EP3651736B1 (en) 2017-07-14 2021-06-23 Janssen Pharmaceutica NV Long-acting formulations
AU2021303490A1 (en) 2020-07-09 2023-03-09 Janssen Pharmaceutica Nv Long-acting formulations
US20240277614A1 (en) 2020-07-09 2024-08-22 Janssen Pharmaceutica Nv Long-acting formulations
WO2022008645A1 (en) 2020-07-09 2022-01-13 Janssen Pharmaceutica Nv Long-acting formulations

Also Published As

Publication number Publication date
ES2891976T3 (es) 2022-02-01
JP7441276B2 (ja) 2024-02-29
CA3069069A1 (en) 2019-01-17
EP4356968A2 (en) 2024-04-24
UA126403C2 (uk) 2022-09-28
DK3651736T3 (da) 2021-09-27
JP7102500B2 (ja) 2022-07-19
SMT202400033T1 (it) 2024-03-13
CO2020000328A2 (es) 2020-01-31
FI3943070T3 (fi) 2024-01-24
JP2022130709A (ja) 2022-09-06
KR20200028964A (ko) 2020-03-17
JOP20200004A1 (ar) 2020-01-14
HRP20211450T1 (hr) 2022-01-07
MX393782B (es) 2025-03-24
SI3651736T1 (sl) 2021-11-30
EP3943070A1 (en) 2022-01-26
CN115252548A (zh) 2022-11-01
ZA202000215B (en) 2021-07-28
LT3943070T (lt) 2024-02-12
PL3943070T3 (pl) 2024-05-06
RS65207B1 (sr) 2024-03-29
DK3943070T3 (da) 2024-01-22
KR102679979B1 (ko) 2024-06-28
LT3651736T (lt) 2021-10-11
SMT202100557T1 (it) 2021-11-12
EP3651736A1 (en) 2020-05-20
ES2970801T3 (es) 2024-05-30
SI3943070T1 (sl) 2024-03-29
RS62362B1 (sr) 2021-10-29
MD3651736T2 (ro) 2021-12-31
HUE064651T2 (hu) 2024-04-28
JP2020526538A (ja) 2020-08-31
EP3651736B1 (en) 2021-06-23
AU2018298855B2 (en) 2024-07-18
SA520410975B1 (ar) 2022-07-16
EP3943070B1 (en) 2023-11-22
CN110869004A (zh) 2020-03-06
CY1124782T1 (el) 2022-11-25
US20210085620A1 (en) 2021-03-25
CN110869004B (zh) 2022-06-14
US12171887B2 (en) 2024-12-24
JP7620692B2 (ja) 2025-01-23
WO2019012100A1 (en) 2019-01-17
BR112020000687A2 (pt) 2020-07-14
JP2024038043A (ja) 2024-03-19
JOP20200004B1 (ar) 2023-09-17
HRP20240058T1 (hr) 2024-03-29
EP4356968A3 (en) 2024-07-10
KR20240108542A (ko) 2024-07-09
PH12020500076A1 (en) 2020-11-09
AU2018298855A1 (en) 2020-01-16
PL3651736T3 (pl) 2021-12-20
US11141384B2 (en) 2021-10-12
US20220047522A1 (en) 2022-02-17
HUE055762T2 (hu) 2021-12-28

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