LT3651736T - Ilgai veikiančios kompozicijos - Google Patents

Ilgai veikiančios kompozicijos

Info

Publication number
LT3651736T
LT3651736T LTEPPCT/EP2018/069066T LT18069066T LT3651736T LT 3651736 T LT3651736 T LT 3651736T LT 18069066 T LT18069066 T LT 18069066T LT 3651736 T LT3651736 T LT 3651736T
Authority
LT
Lithuania
Prior art keywords
long
term compositions
compositions
term
Prior art date
Application number
LTEPPCT/EP2018/069066T
Other languages
English (en)
Lithuanian (lt)
Inventor
Koenraad Andries
Maristella BERNINI
Esther Basstanie
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LT3651736T publication Critical patent/LT3651736T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LTEPPCT/EP2018/069066T 2017-07-14 2018-07-13 Ilgai veikiančios kompozicijos LT3651736T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17181354 2017-07-14
EP18167463 2018-04-16
PCT/EP2018/069066 WO2019012100A1 (en) 2017-07-14 2018-07-13 EXTENDED ACTION FORMULATIONS

Publications (1)

Publication Number Publication Date
LT3651736T true LT3651736T (lt) 2021-10-11

Family

ID=62874924

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2018/069066T LT3651736T (lt) 2017-07-14 2018-07-13 Ilgai veikiančios kompozicijos
LTEP21178526.6T LT3943070T (lt) 2017-07-14 2018-07-13 Ilgo veikimo bedakvilino preparatai

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP21178526.6T LT3943070T (lt) 2017-07-14 2018-07-13 Ilgo veikimo bedakvilino preparatai

Country Status (29)

Country Link
US (2) US11141384B2 (enExample)
EP (3) EP3651736B1 (enExample)
JP (3) JP7102500B2 (enExample)
KR (2) KR102679979B1 (enExample)
CN (2) CN110869004B (enExample)
AU (1) AU2018298855B2 (enExample)
BR (1) BR112020000687A2 (enExample)
CA (1) CA3069069A1 (enExample)
CO (1) CO2020000328A2 (enExample)
CY (1) CY1124782T1 (enExample)
DK (2) DK3651736T3 (enExample)
ES (2) ES2891976T3 (enExample)
FI (1) FI3943070T3 (enExample)
HR (2) HRP20240058T1 (enExample)
HU (2) HUE064651T2 (enExample)
JO (1) JOP20200004B1 (enExample)
LT (2) LT3651736T (enExample)
MD (1) MD3651736T2 (enExample)
MX (1) MX393782B (enExample)
PE (1) PE20200336A1 (enExample)
PH (1) PH12020500076A1 (enExample)
PL (2) PL3651736T3 (enExample)
RS (2) RS65207B1 (enExample)
SA (1) SA520410975B1 (enExample)
SI (2) SI3943070T1 (enExample)
SM (2) SMT202400033T1 (enExample)
UA (1) UA126403C2 (enExample)
WO (1) WO2019012100A1 (enExample)
ZA (1) ZA202000215B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3943070T1 (sl) 2017-07-14 2024-03-29 Janssen Pharmaceutica Nv, Dolgo delujoče formulacije bedakilina
JP7654544B2 (ja) * 2018-12-13 2025-04-01 マンカインド コーポレイション ベダキリンの組成物、それらを含む組み合わせ、それらを調製するための方法、それらを含む使用及び治療方法
CA3182854A1 (en) * 2020-07-09 2022-01-13 Rene Holm Long-acting formulations
US20240277614A1 (en) * 2020-07-09 2024-08-22 Janssen Pharmaceutica Nv Long-acting formulations
MX2023000439A (es) 2020-07-09 2023-02-09 Janssen Pharmaceutica Nv Formulaciones a largo plazo.
KR20230107275A (ko) * 2020-11-12 2023-07-14 얀센 파마슈티카 엔.브이. 비결핵성 마이코박테리아 질환의 치료에서 베다퀼린, 에탐부톨 및 마크롤라이드의 조합물
US11793808B2 (en) 2021-02-22 2023-10-24 Mannkind Corp. Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them
WO2024068699A1 (en) 2022-09-28 2024-04-04 Janssen Pharmaceutica Nv Long-acting formulations
WO2024068693A1 (en) 2022-09-28 2024-04-04 Janssen Pharmaceutica Nv Long-acting formulations

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5346702A (en) 1992-12-04 1994-09-13 Sterling Winthrop Inc. Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization
US5352459A (en) 1992-12-16 1994-10-04 Sterling Winthrop Inc. Use of purified surface modifiers to prevent particle aggregation during sterilization
US6495534B2 (en) 2000-05-15 2002-12-17 Pharmacia & Upjohn Spa Stabilized aqueous suspensions for parenteral use
DK2301544T3 (da) * 2002-07-25 2013-01-02 Janssen Pharmaceutica Nv Quinolinderivater som mellemprodukter til mykobakterielle inhibitorer
EE05394B1 (et) 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis
PT1888604E (pt) 2005-05-25 2012-05-28 Janssen Pharmaceutica Nv Processo para preparar (alfa s, beta r)-6-bromo-alfa-[2- (dimetilamino)etil]-2-metoxi-alfa-1-naftalenil-beta-fenil- 3-quinolinoetanol
HUE068406T2 (hu) 2006-06-23 2024-12-28 Janssen Sciences Ireland Unlimited Co A TMC278 vizes szuszpenziója
UA97813C2 (uk) 2006-12-05 2012-03-26 Янссен Фармацевтика Н.В. Фумаратна сіль (альфа s, бета r)-6-бром-альфа-[2-(диметиламіно)етил]-2-метоксі-альфа-1-нафталеніл-бета-феніл-3-хінолінетанолу
TW201023912A (en) 2008-12-05 2010-07-01 Alcon Res Ltd Pharmaceutical suspension
US9421194B2 (en) 2010-04-05 2016-08-23 Rutgers, The State University Of New Jersey Lung targeting dual drug delivery system
TWI577377B (zh) 2010-09-16 2017-04-11 Viiv醫療保健公司 醫藥組合物
CA2832410C (en) 2011-04-15 2019-07-23 Janssen Pharmaceutica Nv Freeze dried drug nanosuspensions
EP3177366A4 (en) 2014-08-08 2018-04-04 Pharmacyclics LLC Bruton's tyrosine kinase inhibitor combinations and uses thereof
FI3250182T3 (fi) 2015-01-27 2023-06-28 Janssen Pharmaceutica Nv Dispergoituvia koostumuksia
US10653679B2 (en) * 2015-05-04 2020-05-19 Board Of Trustees Of Michigan State University Compositions and methods for inhibiting bacterial growth
HK1254620A1 (zh) 2015-10-14 2019-07-26 结核病药物开发全球联盟公司 联合抗菌组合物以及短疗程抗菌方案
RU2018111482A (ru) * 2015-10-20 2019-11-21 Чжэцзян Хисунь Фармасьютикал Ко., Лтд. Кристаллические формы бедаквилин фумарата и способы их получения
WO2018226512A1 (en) 2017-06-06 2018-12-13 Merck Sharp & Dohme Corp. Long-action implant for treatment of infectious diseases
SI3943070T1 (sl) 2017-07-14 2024-03-29 Janssen Pharmaceutica Nv, Dolgo delujoče formulacije bedakilina
MX2023000439A (es) 2020-07-09 2023-02-09 Janssen Pharmaceutica Nv Formulaciones a largo plazo.
US20240277614A1 (en) 2020-07-09 2024-08-22 Janssen Pharmaceutica Nv Long-acting formulations
CA3182854A1 (en) 2020-07-09 2022-01-13 Rene Holm Long-acting formulations

Also Published As

Publication number Publication date
EP4356968A3 (en) 2024-07-10
US11141384B2 (en) 2021-10-12
ES2970801T3 (es) 2024-05-30
US20220047522A1 (en) 2022-02-17
WO2019012100A1 (en) 2019-01-17
SI3943070T1 (sl) 2024-03-29
JP2022130709A (ja) 2022-09-06
JP7102500B2 (ja) 2022-07-19
EP3943070B1 (en) 2023-11-22
US12171887B2 (en) 2024-12-24
SMT202100557T1 (it) 2021-11-12
RS65207B1 (sr) 2024-03-29
ZA202000215B (en) 2021-07-28
KR20200028964A (ko) 2020-03-17
SI3651736T1 (sl) 2021-11-30
PL3943070T3 (pl) 2024-05-06
JP2024038043A (ja) 2024-03-19
MD3651736T2 (ro) 2021-12-31
AU2018298855B2 (en) 2024-07-18
HUE055762T2 (hu) 2021-12-28
DK3943070T3 (da) 2024-01-22
HRP20211450T1 (hr) 2022-01-07
SMT202400033T1 (it) 2024-03-13
US20210085620A1 (en) 2021-03-25
EP3651736B1 (en) 2021-06-23
CA3069069A1 (en) 2019-01-17
JP7441276B2 (ja) 2024-02-29
HRP20240058T1 (hr) 2024-03-29
EP4356968A2 (en) 2024-04-24
HUE064651T2 (hu) 2024-04-28
SA520410975B1 (ar) 2022-07-16
BR112020000687A2 (pt) 2020-07-14
RS62362B1 (sr) 2021-10-29
ES2891976T3 (es) 2022-02-01
CN110869004A (zh) 2020-03-06
PH12020500076A1 (en) 2020-11-09
EP3651736A1 (en) 2020-05-20
DK3651736T3 (da) 2021-09-27
JOP20200004B1 (ar) 2023-09-17
JOP20200004A1 (ar) 2020-01-14
CO2020000328A2 (es) 2020-01-31
CN115252548A (zh) 2022-11-01
LT3943070T (lt) 2024-02-12
KR20240108542A (ko) 2024-07-09
CN110869004B (zh) 2022-06-14
KR102679979B1 (ko) 2024-06-28
EP3943070A1 (en) 2022-01-26
UA126403C2 (uk) 2022-09-28
MX393782B (es) 2025-03-24
JP2020526538A (ja) 2020-08-31
JP7620692B2 (ja) 2025-01-23
PE20200336A1 (es) 2020-02-14
FI3943070T3 (fi) 2024-01-24
CY1124782T1 (el) 2022-11-25
PL3651736T3 (pl) 2021-12-20
AU2018298855A1 (en) 2020-01-16

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