LT3943070T - Ilgo veikimo bedakvilino preparatai - Google Patents

Ilgo veikimo bedakvilino preparatai

Info

Publication number
LT3943070T
LT3943070T LTEP21178526.6T LT21178526T LT3943070T LT 3943070 T LT3943070 T LT 3943070T LT 21178526 T LT21178526 T LT 21178526T LT 3943070 T LT3943070 T LT 3943070T
Authority
LT
Lithuania
Prior art keywords
bedaquiline
long
acting formulations
formulations
acting
Prior art date
Application number
LTEP21178526.6T
Other languages
English (en)
Inventor
Koenraad Andries
Esther Basstanie
Maristella BERNINI
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LT3943070T publication Critical patent/LT3943070T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LTEP21178526.6T 2017-07-14 2018-07-13 Ilgo veikimo bedakvilino preparatai LT3943070T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17181354 2017-07-14
EP18167463 2018-04-16

Publications (1)

Publication Number Publication Date
LT3943070T true LT3943070T (lt) 2024-02-12

Family

ID=62874924

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2018/069066T LT3651736T (lt) 2017-07-14 2018-07-13 Ilgai veikiančios kompozicijos
LTEP21178526.6T LT3943070T (lt) 2017-07-14 2018-07-13 Ilgo veikimo bedakvilino preparatai

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2018/069066T LT3651736T (lt) 2017-07-14 2018-07-13 Ilgai veikiančios kompozicijos

Country Status (27)

Country Link
US (2) US11141384B2 (lt)
EP (3) EP4356968A2 (lt)
JP (3) JP7102500B2 (lt)
KR (1) KR20200028964A (lt)
CN (2) CN110869004B (lt)
AU (1) AU2018298855A1 (lt)
BR (1) BR112020000687A2 (lt)
CA (1) CA3069069A1 (lt)
CO (1) CO2020000328A2 (lt)
CY (1) CY1124782T1 (lt)
DK (2) DK3651736T3 (lt)
ES (2) ES2891976T3 (lt)
FI (1) FI3943070T3 (lt)
HR (2) HRP20211450T1 (lt)
HU (2) HUE064651T2 (lt)
JO (1) JOP20200004B1 (lt)
LT (2) LT3651736T (lt)
MD (1) MD3651736T2 (lt)
PE (1) PE20200336A1 (lt)
PH (1) PH12020500076A1 (lt)
PL (2) PL3943070T3 (lt)
RS (2) RS65207B1 (lt)
SA (1) SA520410975B1 (lt)
SI (2) SI3651736T1 (lt)
UA (1) UA126403C2 (lt)
WO (1) WO2019012100A1 (lt)
ZA (1) ZA202000215B (lt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020123336A1 (en) * 2018-12-13 2020-06-18 Qrumpharma Inc. Compositions of bedaquiline, combinations comprising them, processes for their preparation, uses and methods of treatment comprising them
CA3184868A1 (en) 2020-07-09 2022-01-13 Rene Holm Long-acting formulations
JP2023532982A (ja) 2020-07-09 2023-08-01 ヤンセン ファーマシューティカ エヌ.ベー. 長時間作用型配合物
CN115867259A (zh) 2020-07-09 2023-03-28 詹森药业有限公司 长效配制品
US11793808B2 (en) 2021-02-22 2023-10-24 Mannkind Corp. Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them
WO2024068693A1 (en) 2022-09-28 2024-04-04 Janssen Pharmaceutica Nv Long-acting formulations
WO2024068699A1 (en) 2022-09-28 2024-04-04 Janssen Pharmaceutica Nv Long-acting formulations

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
AP2421A (en) 2002-07-25 2012-06-08 Janssen Pharmaceutica Nl Quinoline derivatives and their use as mycobacterial inhibitors.
EE05394B1 (et) 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis
NZ563819A (en) 2005-05-25 2011-01-28 Janssen Pharmaceutica Nv Process for preparing (alpha S, beta R)-6-bromo-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-napthalenyl-beta-phenyl-3-quinolineethanol (R207910)
PL2040671T3 (pl) * 2006-06-23 2018-08-31 Janssen Sciences Ireland Uc Wodne zawiesiny TMC278
MX362344B (es) 2011-04-15 2019-01-11 Janssen Pharmaceutica Nv Nanosuspensiones de farmacos secadas por congelamiento.
IL310920A (en) 2015-01-27 2024-04-01 Janssen Pharmaceutica Nv dispersible preparations
US10653679B2 (en) * 2015-05-04 2020-05-19 Board Of Trustees Of Michigan State University Compositions and methods for inhibiting bacterial growth
KR102106318B1 (ko) * 2015-10-20 2020-05-06 쯔지앙 하이썬 파머슈티컬 컴퍼니, 리미티드 베다퀼린 푸마레이트의 결정형 및 그의 제조방법
WO2018226512A1 (en) 2017-06-06 2018-12-13 Merck Sharp & Dohme Corp. Long-action implant for treatment of infectious diseases

Also Published As

Publication number Publication date
JP2024038043A (ja) 2024-03-19
ES2970801T3 (es) 2024-05-30
JOP20200004B1 (ar) 2023-09-17
PL3651736T3 (pl) 2021-12-20
HRP20240058T1 (hr) 2024-03-29
CN115252548A (zh) 2022-11-01
US20220047522A1 (en) 2022-02-17
SA520410975B1 (ar) 2022-07-16
RS62362B1 (sr) 2021-10-29
EP3651736B1 (en) 2021-06-23
UA126403C2 (uk) 2022-09-28
DK3651736T3 (da) 2021-09-27
DK3943070T3 (da) 2024-01-22
HUE064651T2 (hu) 2024-04-28
CO2020000328A2 (es) 2020-01-31
EP3943070B1 (en) 2023-11-22
HRP20211450T1 (hr) 2022-01-07
CY1124782T1 (el) 2022-11-25
EP3651736A1 (en) 2020-05-20
ZA202000215B (en) 2021-07-28
WO2019012100A1 (en) 2019-01-17
JP2022130709A (ja) 2022-09-06
MD3651736T2 (ro) 2021-12-31
BR112020000687A2 (pt) 2020-07-14
KR20200028964A (ko) 2020-03-17
ES2891976T3 (es) 2022-02-01
SI3943070T1 (sl) 2024-03-29
CN110869004A (zh) 2020-03-06
US20210085620A1 (en) 2021-03-25
FI3943070T3 (fi) 2024-01-24
EP4356968A2 (en) 2024-04-24
EP3943070A1 (en) 2022-01-26
RS65207B1 (sr) 2024-03-29
JOP20200004A1 (ar) 2020-01-14
CA3069069A1 (en) 2019-01-17
SI3651736T1 (sl) 2021-11-30
JP2020526538A (ja) 2020-08-31
US11141384B2 (en) 2021-10-12
PH12020500076A1 (en) 2020-11-09
CN110869004B (zh) 2022-06-14
PE20200336A1 (es) 2020-02-14
JP7441276B2 (ja) 2024-02-29
PL3943070T3 (pl) 2024-05-06
JP7102500B2 (ja) 2022-07-19
LT3651736T (lt) 2021-10-11
AU2018298855A1 (en) 2020-01-16
HUE055762T2 (hu) 2021-12-28

Similar Documents

Publication Publication Date Title
IL273541A (en) formulations
IL268697A (en) Formulations
IL269630A (en) Niraprib formulations
IL269621A (en) Niraparib formulations
IL265609A (en) New formulations
FI3943070T3 (fi) Pitkävaikutteisia bedakiliiniformulaatioita
IL273282A (en) Niraprib formulations
GB201607918D0 (en) Novel formulations
GB201707189D0 (en) Novel formulations
ZA201905379B (en) 1-amino-1-cyclopropanecaboxylic acid formulations
GB201707188D0 (en) Novel formulations
IL272857A (en) Cofanalisib formulations
IL267279A (en) Pharmaceutical formulations of suvorexant
GB201707187D0 (en) Novel formulations
PT3678644T (pt) Formulações de copanlisib
IL258420A (en) Stable formulations of fingolimod
PT3943070T (pt) Formulações de ação prolongada de bedaquilina
GB201716291D0 (en) Novel formulations
GB201707564D0 (en) Novel formulations
GB201707562D0 (en) Novel formulations
GB201707190D0 (en) Novel Formulations
GB201714461D0 (en) Formulations
GB201617866D0 (en) Novel formulations
GB201611620D0 (en) Novel formulations of valsartan
GB201611600D0 (en) Novel formulations of valsartan