RS65207B1 - Formulacije bedakvilina sa dugim delovanjem - Google Patents
Formulacije bedakvilina sa dugim delovanjemInfo
- Publication number
- RS65207B1 RS65207B1 RS20240102A RSP20240102A RS65207B1 RS 65207 B1 RS65207 B1 RS 65207B1 RS 20240102 A RS20240102 A RS 20240102A RS P20240102 A RSP20240102 A RS P20240102A RS 65207 B1 RS65207 B1 RS 65207B1
- Authority
- RS
- Serbia
- Prior art keywords
- bedaquiline
- long
- acting formulations
- formulations
- acting
- Prior art date
Links
- QUIJNHUBAXPXFS-XLJNKUFUSA-N bedaquiline Chemical compound C1([C@H](C2=CC3=CC(Br)=CC=C3N=C2OC)[C@@](O)(CCN(C)C)C=2C3=CC=CC=C3C=CC=2)=CC=CC=C1 QUIJNHUBAXPXFS-XLJNKUFUSA-N 0.000 title 1
- 229960000508 bedaquiline Drugs 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17181354 | 2017-07-14 | ||
| EP18167463 | 2018-04-16 | ||
| EP21178526.6A EP3943070B1 (en) | 2017-07-14 | 2018-07-13 | Long-acting formulations of bedaquiline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS65207B1 true RS65207B1 (sr) | 2024-03-29 |
Family
ID=62874924
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20240102A RS65207B1 (sr) | 2017-07-14 | 2018-07-13 | Formulacije bedakvilina sa dugim delovanjem |
| RS20211178A RS62362B1 (sr) | 2017-07-14 | 2018-07-13 | Formulacije sa dugotrajnim dejstvom |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20211178A RS62362B1 (sr) | 2017-07-14 | 2018-07-13 | Formulacije sa dugotrajnim dejstvom |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US11141384B2 (sr) |
| EP (3) | EP4356968A3 (sr) |
| JP (3) | JP7102500B2 (sr) |
| KR (2) | KR102679979B1 (sr) |
| CN (2) | CN115252548A (sr) |
| AU (1) | AU2018298855B2 (sr) |
| BR (1) | BR112020000687A2 (sr) |
| CA (1) | CA3069069A1 (sr) |
| CO (1) | CO2020000328A2 (sr) |
| CY (1) | CY1124782T1 (sr) |
| DK (2) | DK3651736T3 (sr) |
| ES (2) | ES2970801T3 (sr) |
| FI (1) | FI3943070T3 (sr) |
| HR (2) | HRP20240058T1 (sr) |
| HU (2) | HUE055762T2 (sr) |
| JO (1) | JOP20200004B1 (sr) |
| LT (2) | LT3651736T (sr) |
| MD (1) | MD3651736T2 (sr) |
| PE (1) | PE20200336A1 (sr) |
| PH (1) | PH12020500076A1 (sr) |
| PL (2) | PL3943070T3 (sr) |
| RS (2) | RS65207B1 (sr) |
| SA (1) | SA520410975B1 (sr) |
| SI (2) | SI3651736T1 (sr) |
| UA (1) | UA126403C2 (sr) |
| WO (1) | WO2019012100A1 (sr) |
| ZA (1) | ZA202000215B (sr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020123336A1 (en) * | 2018-12-13 | 2020-06-18 | Qrumpharma Inc. | Compositions of bedaquiline, combinations comprising them, processes for their preparation, uses and methods of treatment comprising them |
| WO2022008643A1 (en) | 2020-07-09 | 2022-01-13 | Janssen Pharmaceutica Nv | Long-acting formulations |
| JP2023532982A (ja) | 2020-07-09 | 2023-08-01 | ヤンセン ファーマシューティカ エヌ．ベー． | 長時間作用型配合物 |
| EP4178540A1 (en) | 2020-07-09 | 2023-05-17 | JANSSEN Pharmaceutica NV | Long-acting formulations |
| US11793808B2 (en) | 2021-02-22 | 2023-10-24 | Mannkind Corp. | Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them |
| WO2024068699A1 (en) | 2022-09-28 | 2024-04-04 | Janssen Pharmaceutica Nv | Long-acting formulations |
| WO2024068693A1 (en) | 2022-09-28 | 2024-04-04 | Janssen Pharmaceutica Nv | Long-acting formulations |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| JP4484703B2 (ja) * | 2002-07-25 | 2010-06-16 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | キノリン誘導体およびミコバクテリア抑制剤としてのそれらの使用 |
| EE05394B1 (et) | 2004-12-24 | 2011-04-15 | Janssen Pharmaceutica N.V. | Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis |
| JP5410749B2 (ja) | 2005-05-25 | 2014-02-05 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | （アルファｓ，ベータｒ）−６−ブロモ−アルファ−［２−（ジメチルアミノ）エチル］−２−メトキシ−アルファ−１−ナフタレニル−ベータ−フェニル−３−キノリンエタノールの製造方法 |
| CL2007001847A1 (es) * | 2006-06-23 | 2008-02-08 | Tibotec Pharm Ltd | Composicion farmaceutica intramuscular o subcutanea que comprende tmc278 (rilpivirina); proceso para preparar la composicion; y uso para el tratamiento o prevencion de infeccion por vih. |
| BR112013026363B1 (pt) | 2011-04-15 | 2021-10-13 | Janssen Pharmaceutica Nv | Nanossuspensões compreendendo 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]amino]-2-pirimidinil] amino] benzonitrila, seu processo de preparação e composição farmacêutica para administração por injeção intramuscular ou subcutânea |
| MA41411B1 (fr) | 2015-01-27 | 2023-07-31 | Janssen Pharmaceutica Nv | Compositions dispersibles |
| WO2016179231A1 (en) * | 2015-05-04 | 2016-11-10 | Board Of Trustees Of Michigan State University | Compositions and methods for inhibiting bacterial growth |
| WO2017066926A1 (zh) * | 2015-10-20 | 2017-04-27 | 浙江海正药业股份有限公司 | 富马酸贝达喹啉的晶型及其制备方法 |
| US20200179273A1 (en) | 2017-06-06 | 2020-06-11 | Merck Sharp & DohmeCorp | Long-action implant for treatment of infectious diseases |
-
2018
- 2018-07-13 RS RS20240102A patent/RS65207B1/sr unknown
- 2018-07-13 KR KR1020207003364A patent/KR102679979B1/ko active IP Right Grant
- 2018-07-13 EP EP23206129.1A patent/EP4356968A3/en active Pending
- 2018-07-13 LT LTEPPCT/EP2018/069066T patent/LT3651736T/lt unknown
- 2018-07-13 PL PL21178526.6T patent/PL3943070T3/pl unknown
- 2018-07-13 PL PL18739856T patent/PL3651736T3/pl unknown
- 2018-07-13 HU HUE18739856A patent/HUE055762T2/hu unknown
- 2018-07-13 RS RS20211178A patent/RS62362B1/sr unknown
- 2018-07-13 MD MDE20200530T patent/MD3651736T2/ro unknown
- 2018-07-13 DK DK18739856.5T patent/DK3651736T3/da active
- 2018-07-13 AU AU2018298855A patent/AU2018298855B2/en active Active
- 2018-07-13 HU HUE21178526A patent/HUE064651T2/hu unknown
- 2018-07-13 DK DK21178526.6T patent/DK3943070T3/da active
- 2018-07-13 SI SI201830409T patent/SI3651736T1/sl unknown
- 2018-07-13 WO PCT/EP2018/069066 patent/WO2019012100A1/en unknown
- 2018-07-13 HR HRP20240058TT patent/HRP20240058T1/hr unknown
- 2018-07-13 FI FIEP21178526.6T patent/FI3943070T3/fi active
- 2018-07-13 KR KR1020247021329A patent/KR20240108542A/ko not_active Application Discontinuation
- 2018-07-13 HR HRP20211450TT patent/HRP20211450T1/hr unknown
- 2018-07-13 US US16/630,676 patent/US11141384B2/en active Active
- 2018-07-13 CA CA3069069A patent/CA3069069A1/en active Pending
- 2018-07-13 BR BR112020000687-4A patent/BR112020000687A2/pt unknown
- 2018-07-13 UA UAA202000901A patent/UA126403C2/uk unknown
- 2018-07-13 EP EP18739856.5A patent/EP3651736B1/en active Active
- 2018-07-13 JO JOP/2020/0004A patent/JOP20200004B1/ar active
- 2018-07-13 SI SI201930692T patent/SI3943070T1/sl unknown
- 2018-07-13 EP EP21178526.6A patent/EP3943070B1/en active Active
- 2018-07-13 CN CN202210671005.1A patent/CN115252548A/zh active Pending
- 2018-07-13 CN CN201880046696.8A patent/CN110869004B/zh active Active
- 2018-07-13 ES ES21178526T patent/ES2970801T3/es active Active
- 2018-07-13 JP JP2020501137A patent/JP7102500B2/ja active Active
- 2018-07-13 LT LTEP21178526.6T patent/LT3943070T/lt unknown
- 2018-07-13 ES ES18739856T patent/ES2891976T3/es active Active
- 2018-07-13 PE PE2020000033A patent/PE20200336A1/es unknown
-
2020
- 2020-01-06 SA SA520410975A patent/SA520410975B1/ar unknown
- 2020-01-09 PH PH12020500076A patent/PH12020500076A1/en unknown
- 2020-01-13 ZA ZA2020/00215A patent/ZA202000215B/en unknown
- 2020-01-14 CO CONC2020/0000328A patent/CO2020000328A2/es unknown
-
2021
- 2021-09-08 US US17/469,021 patent/US20220047522A1/en active Pending
- 2021-09-23 CY CY20211100837T patent/CY1124782T1/el unknown
-
2022
- 2022-07-06 JP JP2022108846A patent/JP7441276B2/ja active Active
-
2023
- 2023-12-22 JP JP2023216574A patent/JP2024038043A/ja active Pending
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