PE20091928A1 - Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos - Google Patents
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicosInfo
- Publication number
- PE20091928A1 PE20091928A1 PE2009000744A PE2009000744A PE20091928A1 PE 20091928 A1 PE20091928 A1 PE 20091928A1 PE 2009000744 A PE2009000744 A PE 2009000744A PE 2009000744 A PE2009000744 A PE 2009000744A PE 20091928 A1 PE20091928 A1 PE 20091928A1
- Authority
- PE
- Peru
- Prior art keywords
- antagonists
- hormone receptor
- hydroxysustituted
- pyrimidines
- melanin
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 2
- 101000581402 Homo sapiens Melanin-concentrating hormone receptor 1 Proteins 0.000 title 1
- 102000044674 Melanin-concentrating hormone receptor 1 Human genes 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract 2
- -1 PIVOLATE Chemical compound 0.000 abstract 2
- GEAXLHPORCRESC-UHFFFAOYSA-N chlorocyclohexatriene Chemical class ClC1=CC=C=C[CH]1 GEAXLHPORCRESC-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-M dihydrogenphosphate Chemical compound OP(O)([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-M 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- CXHHBNMLPJOKQD-UHFFFAOYSA-M methyl carbonate Chemical compound COC([O-])=O CXHHBNMLPJOKQD-UHFFFAOYSA-M 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5694908P | 2008-05-29 | 2008-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20091928A1 true PE20091928A1 (es) | 2009-12-31 |
Family
ID=41017166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2009000744A PE20091928A1 (es) | 2008-05-29 | 2009-05-27 | Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos |
Country Status (17)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7851622B2 (en) * | 2007-04-25 | 2010-12-14 | Bristol-Myers Squibb Company | Non-basic melanin concentrating hormone receptor-1 antagonists |
| KR101735868B1 (ko) | 2010-02-17 | 2017-05-15 | 다케다 야쿠힌 고교 가부시키가이샤 | 복소고리 화합물 |
| US10406091B2 (en) | 2011-12-06 | 2019-09-10 | Conopco, Inc. | Skin anti-ageing composition |
| IL225900A0 (en) * | 2013-04-22 | 2014-03-31 | Perrigo Api Ltd | A process for the preparation of nicotine that includes the enzymatic reduction of 4-(methylamino)-1-(3-pyridinyl)-1-butanone |
| EP2921856B1 (en) * | 2014-03-18 | 2016-09-14 | Serum Institute Of India Private Limited | A quantitative assay for 4-pyrrolidinopyridine (4-ppy) in polysaccharide-protein conjugate vaccines |
| NZ732573A (en) * | 2014-12-30 | 2019-01-25 | Dow Agrosciences Llc | Use of picolinamide compounds with fungicidal activity |
| RU2702088C2 (ru) | 2014-12-30 | 2019-10-03 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Применение соединений пиколинамида в качестве фунгицидов |
| AU2021206286A1 (en) * | 2020-01-10 | 2024-08-08 | Consynance Therapeutics, Inc. | Therapeutic combinations of drugs and methods of using them |
| HUP2200222A1 (hu) | 2022-06-17 | 2023-12-28 | Richter Gedeon Nyrt | MCHR1 antagonisták a Prader-Willi szindróma kezelésére |
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| RU2266906C1 (ru) | 2004-04-29 | 2005-12-27 | Общество с ограниченной ответственностью "Исследовательский Институт Химического Разнообразия" (ООО "Исследовательский Институт Химического Разнообразия") | Анелированные карбамоилазагетероциклы, способы их получения (варианты), фармацевтическая композиция, фокусированная библиотека |
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| AR056155A1 (es) | 2005-10-26 | 2007-09-19 | Bristol Myers Squibb Co | Antagonistas del receptor 1 de la hormona de concentracion de melanina no basica |
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-
2009
- 2009-05-27 PE PE2009000744A patent/PE20091928A1/es not_active Application Discontinuation
- 2009-05-28 EA EA201001882A patent/EA201001882A1/ru unknown
- 2009-05-28 US US12/473,346 patent/US7989433B2/en active Active
- 2009-05-28 MX MX2010012803A patent/MX2010012803A/es not_active Application Discontinuation
- 2009-05-28 AU AU2009251331A patent/AU2009251331A1/en not_active Abandoned
- 2009-05-28 JP JP2011511814A patent/JP2011521962A/ja not_active Withdrawn
- 2009-05-28 EP EP09755726A patent/EP2310394A1/en not_active Withdrawn
- 2009-05-28 CA CA2726264A patent/CA2726264A1/en not_active Abandoned
- 2009-05-28 KR KR1020107029384A patent/KR20110021988A/ko not_active Withdrawn
- 2009-05-28 CN CN2009801280666A patent/CN102099360A/zh active Pending
- 2009-05-28 BR BRPI0913197A patent/BRPI0913197A2/pt not_active Application Discontinuation
- 2009-05-28 AR ARP090101925A patent/AR075260A1/es unknown
- 2009-05-28 WO PCT/US2009/045452 patent/WO2009146365A1/en not_active Ceased
- 2009-06-01 TW TW098118073A patent/TW201000487A/zh unknown
-
2010
- 2010-11-16 IL IL209354A patent/IL209354A0/en unknown
- 2010-11-24 ZA ZA2010/08451A patent/ZA201008451B/en unknown
- 2010-11-30 CO CO10151012A patent/CO6280492A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US7989433B2 (en) | 2011-08-02 |
| JP2011521962A (ja) | 2011-07-28 |
| EA201001882A1 (ru) | 2011-06-30 |
| IL209354A0 (en) | 2011-01-31 |
| CA2726264A1 (en) | 2009-12-03 |
| AU2009251331A1 (en) | 2009-12-03 |
| ZA201008451B (en) | 2012-04-25 |
| BRPI0913197A2 (pt) | 2016-01-12 |
| WO2009146365A1 (en) | 2009-12-03 |
| AR075260A1 (es) | 2011-03-23 |
| US20090298794A1 (en) | 2009-12-03 |
| MX2010012803A (es) | 2010-12-07 |
| CO6280492A2 (es) | 2011-05-20 |
| TW201000487A (en) | 2010-01-01 |
| EP2310394A1 (en) | 2011-04-20 |
| CN102099360A (zh) | 2011-06-15 |
| KR20110021988A (ko) | 2011-03-04 |
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