PE20080850A1 - Agentes que comprenden compuestos marcados con 18f y metodos relacionados - Google Patents
Agentes que comprenden compuestos marcados con 18f y metodos relacionadosInfo
- Publication number
- PE20080850A1 PE20080850A1 PE2007001212A PE2007001212A PE20080850A1 PE 20080850 A1 PE20080850 A1 PE 20080850A1 PE 2007001212 A PE2007001212 A PE 2007001212A PE 2007001212 A PE2007001212 A PE 2007001212A PE 20080850 A1 PE20080850 A1 PE 20080850A1
- Authority
- PE
- Peru
- Prior art keywords
- methyl
- hydroxy
- compounds
- cyane
- dioxo
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-M iodide Chemical compound [I-] XMBWDFGMSWQBCA-UHFFFAOYSA-M 0.000 abstract 1
- VLTRZXGMWDSKGL-UHFFFAOYSA-M perchlorate Inorganic materials [O-]Cl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-M 0.000 abstract 1
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57545—Neuropeptide Y
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06090166A EP1897885A1 (en) | 2006-09-08 | 2006-09-08 | Compounds and methods for F labelled agents |
| EP07090079A EP1985624A3 (en) | 2007-04-23 | 2007-04-23 | Single step method of radiofluorination of biologically active compounds or biomolecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20080850A1 true PE20080850A1 (es) | 2008-09-02 |
Family
ID=39031005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2007001212A PE20080850A1 (es) | 2006-09-08 | 2007-09-10 | Agentes que comprenden compuestos marcados con 18f y metodos relacionados |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8557776B2 (enExample) |
| EP (5) | EP2289564A3 (enExample) |
| JP (2) | JP5603074B2 (enExample) |
| KR (1) | KR20090058553A (enExample) |
| AR (1) | AR062726A1 (enExample) |
| AU (1) | AU2007294124A1 (enExample) |
| BR (1) | BRPI0716554A2 (enExample) |
| CA (2) | CA2662449A1 (enExample) |
| CL (1) | CL2007002620A1 (enExample) |
| CO (1) | CO6150196A2 (enExample) |
| CR (1) | CR10654A (enExample) |
| IL (4) | IL197363A0 (enExample) |
| MA (1) | MA30780B1 (enExample) |
| MX (1) | MX2009002492A (enExample) |
| NO (1) | NO20091428L (enExample) |
| PE (1) | PE20080850A1 (enExample) |
| RU (1) | RU2009112716A (enExample) |
| TN (1) | TN2009000063A1 (enExample) |
| TW (1) | TW200829277A (enExample) |
| WO (1) | WO2008028688A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007294124A1 (en) | 2006-09-08 | 2008-03-13 | Bayer Schering Pharma Aktiengesellschaft | Compounds and methods for 18F labeled agents |
| KR20090119966A (ko) * | 2007-03-01 | 2009-11-23 | 바이엘 쉐링 파마 악티엔게젤샤프트 | 진단 영상화제로서의 18ｆ 플루오로-벤조일 표지된 생물학적 활성 화합물, 벤조트리아졸-1-일옥시-벤조일, 2,5-디옥소-피롤리딘-1-일옥시)벤조일 및 트리메틸암모니오-벤조일 전구체 |
| GB201013808D0 (en) | 2010-08-18 | 2010-09-29 | Ge Healthcare Ltd | Peptide radiotracer compositions |
| WO2012094334A1 (en) * | 2011-01-04 | 2012-07-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | One-step 18f labeling of biological substrates and uses of 18f labeled biological substrates |
| US20140097078A1 (en) * | 2011-06-09 | 2014-04-10 | Ge Healthcare Limited | Distillation device and method |
| EP2970345B1 (en) * | 2013-03-15 | 2019-06-19 | Cancer Targeted Technology LLC | 18f-labeled psma-targeted pet imaging agents |
| GB201314936D0 (en) | 2013-08-21 | 2013-10-02 | Ge Healthcare Ltd | Radiolabelling method |
| GB201322456D0 (en) | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Radiotracer compositions and methods |
| WO2018152339A1 (en) * | 2017-02-17 | 2018-08-23 | Yale University | Radiolabeled pharmaceuticals and methods of making and using same |
| SG11202000167SA (en) | 2017-07-11 | 2020-02-27 | Synthorx Inc | Incorporation of unnatural nucleotides and methods thereof |
| KR20250145137A (ko) | 2017-08-03 | 2025-10-13 | 신톡스, 인크. | 자가면역 질환의 치료를 위한 사이토카인 접합체 |
| AU2019256714A1 (en) * | 2018-04-20 | 2020-11-12 | The General Hospital Corporation | Acetylated prodrugs for delivery across the blood-brain barrier |
| US20200246467A1 (en) | 2019-02-06 | 2020-08-06 | Synthorx, Inc. | Il-2 conjugates and methods of use thereof |
| CN113150065B (zh) * | 2021-03-11 | 2022-07-08 | 武汉英纳氏药业有限公司 | 一种合成肽及其应用 |
| WO2022246118A2 (en) * | 2021-05-20 | 2022-11-24 | The Regents Of The University Of California | Pet imaging tracers |
| EP4692065A1 (en) | 2023-03-31 | 2026-02-11 | Nissan Chemical Corporation | Pyrazole compound and harmful organism control agent |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5723578A (en) * | 1987-09-24 | 1998-03-03 | The Administrators Of Tulane Educational Fund | Peptide analogs of bombesin |
| US5084555A (en) | 1989-08-21 | 1992-01-28 | The Administrators Of The Tulane Educational Fund | An octapeptide bombesin analog |
| WO1989002897A1 (en) | 1987-09-24 | 1989-04-06 | The Administrators Of The Tulane Educational Fund | Therapeutic peptides |
| JP2919889B2 (ja) * | 1988-10-14 | 1999-07-19 | アドミニストレイターズ オブ ザ テューレイン エデュケイショナル ファンド | 治療用ペプチド |
| EP0474769B1 (en) * | 1989-06-02 | 1995-11-08 | Georgetown University | A method for the detection of anti-streptokinase antibodies |
| US6232071B1 (en) | 1990-06-11 | 2001-05-15 | Gilead Sciences, Inc. | Tenascin-C nucleic acid ligands |
| US5244883A (en) | 1990-11-29 | 1993-09-14 | The Administrators Of The Tulane Educational Fund | Nonapeptide bombesin antagonists |
| TW432073B (en) | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| BR9814484A (pt) | 1997-12-24 | 2000-10-10 | Vertex Pharma | "pró-drogas de inibidores de aspartil protease" |
| WO1999033795A1 (en) | 1997-12-24 | 1999-07-08 | Vertex Pharmaceuticals Incorporated | Prodrugs of aspartyl protease inhibitors |
| WO1999033792A2 (en) | 1997-12-24 | 1999-07-08 | Vertex Pharmaceuticals Incorporated | Prodrugs os aspartyl protease inhibitors |
| US6436989B1 (en) | 1997-12-24 | 2002-08-20 | Vertex Pharmaceuticals, Incorporated | Prodrugs of aspartyl protease inhibitors |
| US6639076B1 (en) | 1998-08-18 | 2003-10-28 | Eli Lilly And Company | Growth hormone secretagogues |
| US6855715B1 (en) | 1999-06-14 | 2005-02-15 | Eli Lilly And Company | Serine protease inhibitors |
| WO2002044144A2 (en) | 2000-11-30 | 2002-06-06 | Advanced Research And Technology Institute, Inc. | Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds |
| GB0115927D0 (en) * | 2001-06-29 | 2001-08-22 | Nycomed Amersham Plc | Solid-phase nucleophilic fluorination |
| GB0206750D0 (en) | 2002-03-22 | 2002-05-01 | Amersham Plc | Radiofluorination methods |
| WO2003087069A2 (en) * | 2002-04-09 | 2003-10-23 | Eli Lilly And Company | Dipeptidic growth hormone secretagogues |
| ES2299749T3 (es) * | 2002-08-09 | 2008-06-01 | Astellas Pharma Europe B.V. | Compuestos que se unen a p-selectina. |
| US20080063599A1 (en) | 2002-11-18 | 2008-03-13 | Jorge Setoain Quinquer | Compounds Which Can Be Used To Diagnose And Monitor Diseases Associated With The Formation Of Amyloid Protein Fibrils |
| EP1597270A2 (en) * | 2003-02-20 | 2005-11-23 | University of South Florida | Peptidomimetic inhibitors of stat3 activity and their medical uses |
| GB0305704D0 (en) * | 2003-03-13 | 2003-04-16 | Amersham Plc | Radiofluorination methods |
| WO2006083424A2 (en) | 2004-12-28 | 2006-08-10 | The Trustees Of Columbia University In The City Of New York | Radiolabeled compounds and uses thereof |
| JP2009505962A (ja) | 2005-07-29 | 2009-02-12 | バイエル・ヘルスケア・エルエルシー | 肥満を治療するためのビフェニルアミノ酸誘導体の製造および使用 |
| US20080029548A1 (en) | 2006-05-05 | 2008-02-07 | Ann De Wree | Fabric treatment dispensing package |
| AU2007294124A1 (en) | 2006-09-08 | 2008-03-13 | Bayer Schering Pharma Aktiengesellschaft | Compounds and methods for 18F labeled agents |
-
2007
- 2007-09-07 AU AU2007294124A patent/AU2007294124A1/en not_active Abandoned
- 2007-09-07 EP EP20100183074 patent/EP2289564A3/en not_active Withdrawn
- 2007-09-07 US US11/851,910 patent/US8557776B2/en active Active
- 2007-09-07 EP EP10183062.8A patent/EP2279759A3/en not_active Withdrawn
- 2007-09-07 EP EP11193716.5A patent/EP2455105B1/en active Active
- 2007-09-07 JP JP2009527069A patent/JP5603074B2/ja active Active
- 2007-09-07 RU RU2009112716/15A patent/RU2009112716A/ru not_active Application Discontinuation
- 2007-09-07 KR KR1020097007141A patent/KR20090058553A/ko not_active Ceased
- 2007-09-07 CA CA002662449A patent/CA2662449A1/en not_active Abandoned
- 2007-09-07 WO PCT/EP2007/008042 patent/WO2008028688A2/en not_active Ceased
- 2007-09-07 MX MX2009002492A patent/MX2009002492A/es not_active Application Discontinuation
- 2007-09-07 BR BRPI0716554-4A2A patent/BRPI0716554A2/pt not_active IP Right Cessation
- 2007-09-07 CA CA2858907A patent/CA2858907A1/en not_active Abandoned
- 2007-09-07 EP EP07802326.4A patent/EP2063918B1/en active Active
- 2007-09-07 EP EP16153790.7A patent/EP3056509A1/en not_active Ceased
- 2007-09-10 CL CL200702620A patent/CL2007002620A1/es unknown
- 2007-09-10 AR ARP070103993A patent/AR062726A1/es unknown
- 2007-09-10 PE PE2007001212A patent/PE20080850A1/es not_active Application Discontinuation
- 2007-09-10 TW TW096133780A patent/TW200829277A/zh unknown
-
2009
- 2009-02-27 TN TN2009000063A patent/TN2009000063A1/fr unknown
- 2009-03-03 IL IL197363A patent/IL197363A0/en unknown
- 2009-03-05 CR CR10654A patent/CR10654A/es not_active Application Discontinuation
- 2009-03-06 CO CO09023386A patent/CO6150196A2/es unknown
- 2009-04-06 MA MA31764A patent/MA30780B1/fr unknown
- 2009-04-07 NO NO20091428A patent/NO20091428L/no not_active Application Discontinuation
-
2011
- 2011-02-03 IL IL211033A patent/IL211033A0/en unknown
- 2011-03-03 IL IL211526A patent/IL211526A0/en unknown
- 2011-03-03 IL IL211527A patent/IL211527A0/en unknown
-
2013
- 2013-08-16 JP JP2013169253A patent/JP5722966B2/ja active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR051839A1 (es) | Metodo para preparar n-fenilpirazol -1- carboxamidas | |
| PE20100809A1 (es) | Inhibidores de glutamato de metaloproteinasas de matriz y agrecanasas | |
| RU2370485C2 (ru) | Амидоацетонитрильные производные | |
| AR031295A1 (es) | Pirrolcarboxamidas y pirrolcarbotioxamidas | |
| AR072099A1 (es) | Compuestos para modulacion de cinasas | |
| PE20040374A1 (es) | DERIVADOS DE ACIL-4-CARBOXIFENILUREA COMO INHIBIDORES DE LA GLUCOGENO FOSFORILASA a | |
| MA31763B1 (fr) | Inhibiteurs de kinase de type polo | |
| AR064086A1 (es) | Formulaciones liquidas de artropodicidas de carboxamida | |
| CY1109898T1 (el) | Τεταρτοταγεις ενωσεις αμμωνιου και η χρηση τους ως αντιμουσκαρινικοι παραγοντες | |
| AR066793A1 (es) | Agentes de 3- ciano-4-triazolil fenilsoxazolina para el control de plagas de invertebrados | |
| CL2010000426A1 (es) | Anticuerpo humano que se une al ligando para el ox40 (ox40l o gp34) humano; metodo de produccion; y composicion farmaceutica que lo comprende (div. sol. n°2389-05). | |
| AR078201A1 (es) | Compuestos de 2-piridona y su uso en el tratamiento de enfermedades mediadas por la elastasa de neutrofilos | |
| PE20040892A1 (es) | Antagonistas del receptor muscarinico m3 de acetilcolina | |
| ES2184310T3 (es) | Formulacion autoemulsionante para compuestos lipofilos acidos. | |
| AR043049A1 (es) | Derivados de hidantoina, proceso de preparacion del mismo y composicion farmaceutica | |
| PE20081477A1 (es) | Formulacion liofilizada mab abeta | |
| PE20140381A1 (es) | Dispersiones solidas extruidas por fusion que contienen un agente inductor de apoptosis | |
| AR063449A1 (es) | Proceso quimico para derivados de quinazolina, intermediarios | |
| AR049578A1 (es) | Derivados de hidantoina, procesos de obtencion y composiciones farmaceuticas | |
| PE20090758A1 (es) | Un proceso para la preparacion de compuestos de aminodiol protegidos con oxazolina, utiles como intermediarios para florfenicol | |
| NI200800008A (es) | Métodos para la neuroprotección | |
| AR063906A1 (es) | Compuestos quimicos derivados del indazol, una composicion farmaceutica y procesos de prpeparacion de los compuestos | |
| PE20140792A1 (es) | Composiciones farmaceuticas | |
| BR112022013547A2 (pt) | Métodos para potencializar a farmacocinética, para aumentar a concentração plasmática e a vigília ou diminuir a sonolência excessiva, e, composição | |
| CL2007002620A1 (es) | Compuesto marcado con isotopo de fluor; metodo para preparar dicho compuesto; composicion que comprende dicho compuesto; metodo de tomar imagenes de enfermedades que comprende el compuesto antes mencionado; kit que comprende dicho compuesto. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |