AR063294A1 - Composiciones de carbamatos de fenilalquilo - Google Patents

Composiciones de carbamatos de fenilalquilo

Info

Publication number
AR063294A1
AR063294A1 ARP070104554A ARP070104554A AR063294A1 AR 063294 A1 AR063294 A1 AR 063294A1 AR P070104554 A ARP070104554 A AR P070104554A AR P070104554 A ARP070104554 A AR P070104554A AR 063294 A1 AR063294 A1 AR 063294A1
Authority
AR
Argentina
Prior art keywords
phenyl
alkyl
independently selected
group
compound
Prior art date
Application number
ARP070104554A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39111848&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR063294(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of AR063294A1 publication Critical patent/AR063294A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Composicion de un compuesto carbamato de fenilalquilo que produce una estabilidad mejorada, donde la composicion comprende un compuesto carbamato de fenilalquilo en una mezcla con una cantidad efectiva de uno o más excipientes y donde por lo menos un excipiente es fosfato de calcio dibásico dihidratado. Reivindicacion 29: Un método de preparacion de una composicion que comprende el paso de mezclar una cantidad efectiva de uno o más excipientes donde por lo menos un excipiente es fosfato de calcio dibásico dihidratado con un compuesto de formula (1) o una de sus formas donde fenilo está sustituido en X con uno a cinco átomos de halogeno independientemente seleccionados del grupo que consiste en fluor, cloro, bromo y yodo; y R1 y R2 se seleccionan independientemente del grupo que consiste en hidrogeno y alquilo C1-4; donde alquilo C1-4 está opcionalmente sustituido con fenilo, donde el fenilo está opcionalmente sustituido con sustituyentes seleccionados independientemente del grupo que consiste en halogeno, alquilo C1-4, alcoxi C1-4, amino, nitro y ciano. Reivindicacion 33: Uso de una composicion que comprende una cantidad efectiva de uno o más excipientes donde por lo menos un excipiente es fosfato de calcio dibásico dihidratado y un compuesto de formula (1) o una de sus formas donde fenilo está sustituido en X con uno a cinco átomos de halogeno independientemente seleccionados del grupo que consiste en fluor, cloro, bromo y yodo; y R1 y R2 se seleccionan independientemente del grupo que consiste en hidrogeno y alquilo C1-4; donde alquilo C1-4 está opcionalmente sustituido con fenilo, donde el fenilo está opcionalmente sustituido con sustituyentes seleccionados independientemente del grupo que consiste en halogeno, alquilo C1-4, alcoxi C1-4, amino, nitro y ciano, en la preparacion de un medicamento para el tratamiento de un trastorno del SNC. Reivindicacion 35: El uso de la reivindicacion 33, donde el compuesto es el compuesto de la reivindicacion 4.
ARP070104554A 2006-10-13 2007-10-12 Composiciones de carbamatos de fenilalquilo AR063294A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82935506P 2006-10-13 2006-10-13

Publications (1)

Publication Number Publication Date
AR063294A1 true AR063294A1 (es) 2009-01-21

Family

ID=39111848

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070104554A AR063294A1 (es) 2006-10-13 2007-10-12 Composiciones de carbamatos de fenilalquilo

Country Status (23)

Country Link
US (1) US20080090903A1 (es)
EP (1) EP2089002A1 (es)
JP (1) JP2010506846A (es)
KR (1) KR20090067210A (es)
CN (1) CN101663026A (es)
AR (1) AR063294A1 (es)
AU (1) AU2007313018A1 (es)
BR (1) BRPI0719236A2 (es)
CA (1) CA2673526A1 (es)
CL (1) CL2007002943A1 (es)
CO (1) CO6190539A2 (es)
CR (1) CR10793A (es)
EA (1) EA200970378A1 (es)
IL (1) IL198144A0 (es)
MX (1) MX2009003929A (es)
NI (1) NI200900055A (es)
NO (1) NO20091492L (es)
PE (1) PE20080887A1 (es)
SV (1) SV2009003222A (es)
TW (1) TW200831134A (es)
UY (1) UY30643A1 (es)
WO (1) WO2008048802A1 (es)
ZA (1) ZA200903284B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263652B2 (en) * 2007-10-31 2012-09-11 Sk Biopharmaceuticals Co., Ltd. Stabilized pediatric suspension of carisbamate
US9018253B2 (en) 2010-07-02 2015-04-28 Bio-Pharm Solutions Co., Ltd. Phenylcarbamate compound and muscle relaxant containing the same
ES2711619T3 (es) * 2010-07-02 2019-05-06 Bio Pharm Solutions Co Ltd Compuesto carbamato de fenilo y relajante muscular que contiene dicho compuesto
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CN104136413B (zh) 2011-12-27 2016-10-26 比皮艾思药物研发有限公司 用于预防或治疗癫痫症的苯基氨基甲酸酯化合物
WO2014097137A2 (en) * 2012-12-18 2014-06-26 Mahesh Kandula Compositions and methods for the treatment of seizures and neurologic diseases
CN109939092B (zh) 2013-03-12 2022-03-22 比皮艾思药物研发有限公司 用于预防或治疗小儿癫痫和癫痫相关综合征的苯基氨基甲酸酯化合物
CN105164103B (zh) * 2013-03-12 2019-12-06 比皮艾思药物研发有限公司 苯基氨基甲酸酯化合物和含有其的预防或治疗记忆缺失相关疾病的组合物
US10351519B2 (en) * 2016-02-29 2019-07-16 Bio-Pharm Solutions Co., Ltd. Sulfamate derivative compounds, processes for preparing them and their uses
CA3016124C (en) * 2016-02-29 2022-06-07 Bio-Pharm Solutions Co., Ltd. Carbamate derivative compounds, processes for preparing them and their uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US20010034365A1 (en) * 1996-01-16 2001-10-25 Choi Yong Moon Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US20020147229A1 (en) * 2000-08-17 2002-10-10 Allerton Charlotte Moira Norfor Pharmaceuticals
CN1564691A (zh) * 2001-10-08 2005-01-12 太阳医药工业有限公司 一种止痉挛剂的间隔药物释出系统

Also Published As

Publication number Publication date
KR20090067210A (ko) 2009-06-24
BRPI0719236A2 (pt) 2014-07-08
AU2007313018A1 (en) 2008-04-24
CL2007002943A1 (es) 2008-04-18
SV2009003222A (es) 2009-10-15
NI200900055A (es) 2010-02-01
TW200831134A (en) 2008-08-01
CA2673526A1 (en) 2008-04-24
NO20091492L (no) 2009-07-09
US20080090903A1 (en) 2008-04-17
CR10793A (es) 2009-09-29
MX2009003929A (es) 2009-06-26
UY30643A1 (es) 2008-05-02
IL198144A0 (en) 2009-12-24
JP2010506846A (ja) 2010-03-04
ZA200903284B (en) 2010-07-28
WO2008048802A1 (en) 2008-04-24
EP2089002A1 (en) 2009-08-19
EA200970378A1 (ru) 2009-10-30
CO6190539A2 (es) 2010-08-19
PE20080887A1 (es) 2008-06-28
CN101663026A (zh) 2010-03-03

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