PE20061196A1 - Tetrahidropiridoazepin-8-onas y compuestos relacionados para el tratamiento de la esquizofrenia - Google Patents
Tetrahidropiridoazepin-8-onas y compuestos relacionados para el tratamiento de la esquizofreniaInfo
- Publication number
- PE20061196A1 PE20061196A1 PE2006000353A PE2006000353A PE20061196A1 PE 20061196 A1 PE20061196 A1 PE 20061196A1 PE 2006000353 A PE2006000353 A PE 2006000353A PE 2006000353 A PE2006000353 A PE 2006000353A PE 20061196 A1 PE20061196 A1 PE 20061196A1
- Authority
- PE
- Peru
- Prior art keywords
- ona
- schizophrenia
- treatment
- tetrahidropiridoazepin
- onas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA I, DONDE G ES NAFTALEN, CROMAN, 2,3-DIHIDROBENZOFURAN, ENTRE OTROS; A ES -(CH2)mCH2-, -(CH2)mO-, -(CH2)mNH-; m ES 3-5; D ES N, C, CH; Q, Y, Z SON CADA UNO N, C; R1, R2 Y R3 SON CADA UNO H, HALO, CIANO, HIDROXI, ALCOXI C1-C4, ENTRE OTROS; R4, R5, R6, R7, R8 Y R9 SON CADA UNO H, FLUORO, HIDROXI, ALQUILO C1-C4, ENTRE OTROS; R10 ES H, ALQUILO C1-C4, ALCOXI C1-C4, ENTRE OTROS. SON COMPUESTOS PREFERIDOS: 2-[4-(4-NAFTALEN-1-ILPIPERAZIN-1-IL)BUTOXI]-5,6,7,9-TETRAHIDROPIRIDO[2,3-b]AZEPIN-8-ONA; 8-{4-[4-(2,3-DICLOROFENIL)PIPERAZIN-1-IL]PROPOXI}-1,3,4,5-TETRAHIDROBENZO[d][1,3]DIAZEPIN-2-ONA; 4,4-DIMETIL-8-[3-(4-NAFTALEN-1-ILPIPERAZIN-1-IL)PROPOXI]-1,3,4,5-TETRAHIDROBENZO-[d][1,3]DIAZEPIN-2-ONA; ENTRE OTROS. REFERIDA TAMBIEN A UNA COMPOSICION FARMACEUTICA Y A UN PROCEDIMIENTO DE PREPARACION. DICHOS COMPUESTOS SE UNEN AL RECEPTOR DE DOPAMINA D2 Y SON UTILES EN EL TRATAMIENTO DE TRASTORNOS DEPRESIVOS TALES COMO ESQUIZOFRENIA, TRASTORNO ALUCINATORIO, DELIRIO, DEMENCIA, ENTRE OTROS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66744705P | 2005-04-01 | 2005-04-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20061196A1 true PE20061196A1 (es) | 2006-12-16 |
Family
ID=36763625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2006000353A PE20061196A1 (es) | 2005-04-01 | 2006-03-30 | Tetrahidropiridoazepin-8-onas y compuestos relacionados para el tratamiento de la esquizofrenia |
Country Status (25)
Country | Link |
---|---|
US (1) | US20060234997A1 (es) |
EP (1) | EP1869041A1 (es) |
JP (1) | JP4109709B1 (es) |
KR (1) | KR20070112228A (es) |
CN (1) | CN101189237A (es) |
AP (1) | AP2007004160A0 (es) |
AR (1) | AR053835A1 (es) |
AU (1) | AU2006228426A1 (es) |
BR (1) | BRPI0607918A2 (es) |
CA (1) | CA2603049A1 (es) |
CR (1) | CR9407A (es) |
DO (1) | DOP2006000071A (es) |
EA (1) | EA200701856A1 (es) |
GT (1) | GT200600130A (es) |
IL (1) | IL185770A0 (es) |
MA (1) | MA29989B1 (es) |
MX (1) | MX2007012083A (es) |
NL (2) | NL1031489C2 (es) |
NO (1) | NO20075477L (es) |
PE (1) | PE20061196A1 (es) |
TN (1) | TNSN07366A1 (es) |
TW (1) | TW200714282A (es) |
UY (1) | UY29447A1 (es) |
WO (1) | WO2006103559A1 (es) |
ZA (1) | ZA200708033B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007116265A1 (en) * | 2006-03-31 | 2007-10-18 | Pfizer Products Inc. | Process for making a tetrahydro-pyridoazepin-8-one compound |
US8674790B2 (en) | 2009-12-28 | 2014-03-18 | Seiko Epson Corporation | Surface acoustic wave device, oscillator, module apparatus |
US9156822B2 (en) | 2010-07-02 | 2015-10-13 | The University Of North Carolina At Chapel Hill | Functionally selective ligands of dopamine D2 receptors |
WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
EP3402796B1 (en) | 2016-01-15 | 2020-11-18 | Pfizer Inc | 6,7,8,9-tetrahydro-5h-pyrido[2,3-d]azepine dopamine d3 ligands |
CN109071504B (zh) | 2016-02-05 | 2022-03-08 | 戴纳立制药公司 | 受体相互作用蛋白激酶1的抑制剂 |
DK3552017T3 (da) | 2016-12-09 | 2022-05-16 | Denali Therapeutics Inc | Forbindelser, der er anvendelige som ripk1-inhibitorer |
WO2022212538A1 (en) * | 2021-03-31 | 2022-10-06 | Blueprint Medicines Corporation | Diazepanone-fused pyrimidine compounds, compositions and medicinal applications thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2960178D1 (en) * | 1978-06-06 | 1981-04-09 | Hoechst Ag | New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation |
JPS57193461A (en) * | 1981-05-22 | 1982-11-27 | Otsuka Pharmaceut Co Ltd | Benzazepine derivative |
DK588486A (da) * | 1985-12-09 | 1987-06-10 | Otsuka Pharma Co Ltd | Anvendelse af en forbindelse til behandling af hypoxi |
US5006528A (en) * | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
US5350747A (en) * | 1989-07-07 | 1994-09-27 | Pfizer Inc | Heteroaryl piperazine antipsychotic agents |
AU645681B2 (en) * | 1991-05-02 | 1994-01-20 | John Wyeth & Brother Limited | Piperazine derivatives |
US5206366A (en) * | 1992-08-26 | 1993-04-27 | Pfizer Inc. | Process for preparing aryl piperazinyl-heterocyclic compounds |
FR2699918B1 (fr) * | 1992-12-30 | 1995-03-17 | Pf Medicament | Ligands sélectifs des récepteurs 5HY1D-5HT1B dérivés d'indole-pipérazine utiles comme médicaments. |
US5945422A (en) * | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
DE19747063A1 (de) * | 1997-10-24 | 1999-04-29 | Basf Ag | 3-substituierte Tetrahydropyridopyrimidinon-Derivate, ihre Herstellung und Verwendung |
US7160888B2 (en) * | 2003-08-22 | 2007-01-09 | Warner Lambert Company Llc | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia |
-
2006
- 2006-03-20 JP JP2008503619A patent/JP4109709B1/ja not_active Expired - Fee Related
- 2006-03-20 AU AU2006228426A patent/AU2006228426A1/en not_active Abandoned
- 2006-03-20 EP EP06727493A patent/EP1869041A1/en not_active Withdrawn
- 2006-03-20 MX MX2007012083A patent/MX2007012083A/es unknown
- 2006-03-20 AP AP2007004160A patent/AP2007004160A0/xx unknown
- 2006-03-20 CN CNA2006800197403A patent/CN101189237A/zh active Pending
- 2006-03-20 CA CA002603049A patent/CA2603049A1/en not_active Abandoned
- 2006-03-20 EA EA200701856A patent/EA200701856A1/ru unknown
- 2006-03-20 KR KR1020077022373A patent/KR20070112228A/ko not_active Application Discontinuation
- 2006-03-20 WO PCT/IB2006/000900 patent/WO2006103559A1/en active Application Filing
- 2006-03-20 BR BRPI0607918-0A patent/BRPI0607918A2/pt not_active Application Discontinuation
- 2006-03-28 DO DO2006000071A patent/DOP2006000071A/es unknown
- 2006-03-30 AR ARP060101253A patent/AR053835A1/es unknown
- 2006-03-30 UY UY29447A patent/UY29447A1/es not_active Application Discontinuation
- 2006-03-30 PE PE2006000353A patent/PE20061196A1/es not_active Application Discontinuation
- 2006-03-31 TW TW095111562A patent/TW200714282A/zh unknown
- 2006-03-31 US US11/395,931 patent/US20060234997A1/en not_active Abandoned
- 2006-03-31 NL NL1031489A patent/NL1031489C2/nl not_active IP Right Cessation
- 2006-03-31 GT GT200600130A patent/GT200600130A/es unknown
-
2007
- 2007-03-20 NL NL1033562A patent/NL1033562C2/nl not_active IP Right Cessation
- 2007-09-06 IL IL185770A patent/IL185770A0/en unknown
- 2007-09-18 ZA ZA200708033A patent/ZA200708033B/xx unknown
- 2007-09-28 TN TNP2007000366A patent/TNSN07366A1/fr unknown
- 2007-10-01 CR CR9407A patent/CR9407A/es not_active Application Discontinuation
- 2007-10-01 MA MA30264A patent/MA29989B1/fr unknown
- 2007-10-30 NO NO20075477A patent/NO20075477L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2603049A1 (en) | 2006-10-05 |
KR20070112228A (ko) | 2007-11-22 |
JP2008534574A (ja) | 2008-08-28 |
AP2007004160A0 (en) | 2007-10-31 |
MA29989B1 (fr) | 2008-12-01 |
US20060234997A1 (en) | 2006-10-19 |
IL185770A0 (en) | 2008-01-06 |
EP1869041A1 (en) | 2007-12-26 |
JP4109709B1 (ja) | 2008-07-02 |
NO20075477L (no) | 2007-12-13 |
GT200600130A (es) | 2007-02-14 |
WO2006103559A1 (en) | 2006-10-05 |
NL1033562A1 (nl) | 2007-06-21 |
NL1033562C2 (nl) | 2007-10-23 |
AR053835A1 (es) | 2007-05-23 |
NL1031489A1 (nl) | 2006-10-03 |
TNSN07366A1 (fr) | 2008-12-31 |
EA200701856A1 (ru) | 2008-02-28 |
TW200714282A (en) | 2007-04-16 |
BRPI0607918A2 (pt) | 2009-10-20 |
AU2006228426A1 (en) | 2006-10-05 |
CR9407A (es) | 2008-01-29 |
CN101189237A (zh) | 2008-05-28 |
ZA200708033B (en) | 2008-11-26 |
MX2007012083A (es) | 2007-11-20 |
DOP2006000071A (es) | 2006-10-15 |
NL1031489C2 (nl) | 2007-04-02 |
UY29447A1 (es) | 2006-10-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20061196A1 (es) | Tetrahidropiridoazepin-8-onas y compuestos relacionados para el tratamiento de la esquizofrenia | |
PE20120219A1 (es) | Inhibidores de beta-secretasa | |
MX2015015893A (es) | 2-fenilimidazo[1,2-a]pirimidinas como agentes formadores de imagen. | |
PE20070172A1 (es) | DERIVADOS BICICLICOS COMO INHIBIDORES DE p38 | |
PE20070004A1 (es) | Imidazoquinolinas como inhibidores de quinasa de lipido | |
PE20071156A1 (es) | COMPUESTOS DERIVADOS DE 4,5,6,7-TETRAHIDRO-1H-INDAZOL COMO POTENCIADORES DEL RECEPTOR DEL ACIDO a-AMINO-3-HIDROXI-5-METILISOXAZOL-4-PROPIONICO (AMPA) | |
PE20061150A1 (es) | Derivados de n-(n-sulfonilaminoarilmetil)ciclopropanocarboxamida sustituidos como antagonistas del receptor vainilloide tipo 1 (vdr1) | |
DE602006006850D1 (de) | Als modulatoren von dopamin-d3-rezeptoren geeignete azabicyclo-(3,1,0)-hexan-derivate | |
PE20071009A1 (es) | Compuestos derivados de fenoxipiperidinas como antagonistas de histamina h3 | |
AR035892A1 (es) | Derivados de oxazol, proceso para su preparacion, composiciones farmaceuticas que los comprenden, y el uso de dichos compuestos en la preparacion de medicamentos | |
PE20011371A1 (es) | Derivados de 3-(3-isopropil-5-metil-4h-1,2,4-triazol-4-il)-exo-8-azabiciclo[3.2.1]octano como antagonistas de los receptores de quimiocina ccr5 | |
PE20081851A1 (es) | Derivados de espiropiperidina-glicinamida | |
AR067662A1 (es) | Derivados de benzo[d]isoxazol-3-il-piperidina, medicamentos que los contienen y usos terapeuticos para enfermedades asociadas al sistema nervioso. | |
AR054560A1 (es) | Espiropiperidina como inhibidores de beta-secretasa para el tratamiento de la enfermedad de alzheimer | |
AR061486A1 (es) | Derivados de 2-pirazinacarboxamida | |
CO5700829A2 (es) | Derivados triciclicos de indol y su uso en eltratamiento de la enfermedad de alzheimer | |
PE20060483A1 (es) | Compuestos heterociclicos como antagonistas de nk1 | |
PE20061316A1 (es) | Derivados de pirazol como antagonistas del receptor de progesterona | |
PE20140609A1 (es) | Diazacarbazoles y metodos de uso | |
AR079260A1 (es) | Inhibidores de bencimidazol de la produccion de leucotrienos, un procedimiento para su preparacion, composiciones farmaceuticas que los comprenden y su empleo como medicamentos en el tratamiento de trastornos mediados por leucotrienos | |
AR059328A1 (es) | Derivados de antranilamida-2-amino-heteroareno-carboxamida, un proceso para su obtencion, composiciones farmaceuticas que los contienen y el uso de estos compuestos para la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por cetp | |
AR069480A1 (es) | Derivados de 2-amino-pirimidina | |
PE20061133A1 (es) | DERIVADOS DE AZABENZOXAZOLES COMO AGONISTAS DEL RECEPTOR a7 NICOTINICO | |
PE20100718A1 (es) | Derivados triciclicos de 1, 4-dihidropiridina [b, e]-condensados como inhibidores de aurora quinasas | |
PE20090592A1 (es) | Nuevos derivados de piperazina-amida |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |