AP2007004160A0 - Tetrahydro-pyridoazepin-8-ones and related compounds for the treatment of schizophrenia - Google Patents
Tetrahydro-pyridoazepin-8-ones and related compounds for the treatment of schizophreniaInfo
- Publication number
- AP2007004160A0 AP2007004160A0 AP2007004160A AP2007004160A AP2007004160A0 AP 2007004160 A0 AP2007004160 A0 AP 2007004160A0 AP 2007004160 A AP2007004160 A AP 2007004160A AP 2007004160 A AP2007004160 A AP 2007004160A AP 2007004160 A0 AP2007004160 A0 AP 2007004160A0
- Authority
- AP
- ARIPO
- Prior art keywords
- pyridoazepin
- schizophrenia
- tetrahydro
- ones
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66744705P | 2005-04-01 | 2005-04-01 | |
| PCT/IB2006/000900 WO2006103559A1 (en) | 2005-04-01 | 2006-03-20 | Tetrahydro-pyridoazepin-8-ones and related compounds for the treatment of schizophrenia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AP2007004160A0 true AP2007004160A0 (en) | 2007-10-31 |
Family
ID=36763625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AP2007004160A AP2007004160A0 (en) | 2005-04-01 | 2006-03-20 | Tetrahydro-pyridoazepin-8-ones and related compounds for the treatment of schizophrenia |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20060234997A1 (xx) |
| EP (1) | EP1869041A1 (xx) |
| JP (1) | JP4109709B1 (xx) |
| KR (1) | KR20070112228A (xx) |
| CN (1) | CN101189237A (xx) |
| AP (1) | AP2007004160A0 (xx) |
| AR (1) | AR053835A1 (xx) |
| AU (1) | AU2006228426A1 (xx) |
| BR (1) | BRPI0607918A2 (xx) |
| CA (1) | CA2603049A1 (xx) |
| CR (1) | CR9407A (xx) |
| DO (1) | DOP2006000071A (xx) |
| EA (1) | EA200701856A1 (xx) |
| GT (1) | GT200600130A (xx) |
| IL (1) | IL185770A0 (xx) |
| MA (1) | MA29989B1 (xx) |
| MX (1) | MX2007012083A (xx) |
| NL (2) | NL1031489C2 (xx) |
| NO (1) | NO20075477L (xx) |
| PE (1) | PE20061196A1 (xx) |
| TN (1) | TNSN07366A1 (xx) |
| TW (1) | TW200714282A (xx) |
| UY (1) | UY29447A1 (xx) |
| WO (1) | WO2006103559A1 (xx) |
| ZA (1) | ZA200708033B (xx) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007116265A1 (en) * | 2006-03-31 | 2007-10-18 | Pfizer Products Inc. | Process for making a tetrahydro-pyridoazepin-8-one compound |
| US8674790B2 (en) | 2009-12-28 | 2014-03-18 | Seiko Epson Corporation | Surface acoustic wave device, oscillator, module apparatus |
| US9156822B2 (en) | 2010-07-02 | 2015-10-13 | The University Of North Carolina At Chapel Hill | Functionally selective ligands of dopamine D2 receptors |
| WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| EP3402796B1 (en) | 2016-01-15 | 2020-11-18 | Pfizer Inc | 6,7,8,9-tetrahydro-5h-pyrido[2,3-d]azepine dopamine d3 ligands |
| CN109071504B (zh) | 2016-02-05 | 2022-03-08 | 戴纳立制药公司 | 受体相互作用蛋白激酶1的抑制剂 |
| DK3552017T3 (da) | 2016-12-09 | 2022-05-16 | Denali Therapeutics Inc | Forbindelser, der er anvendelige som ripk1-inhibitorer |
| WO2022212538A1 (en) * | 2021-03-31 | 2022-10-06 | Blueprint Medicines Corporation | Diazepanone-fused pyrimidine compounds, compositions and medicinal applications thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2960178D1 (en) * | 1978-06-06 | 1981-04-09 | Hoechst Ag | New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation |
| JPS57193461A (en) * | 1981-05-22 | 1982-11-27 | Otsuka Pharmaceut Co Ltd | Benzazepine derivative |
| DK588486A (da) * | 1985-12-09 | 1987-06-10 | Otsuka Pharma Co Ltd | Anvendelse af en forbindelse til behandling af hypoxi |
| US5006528A (en) * | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US5350747A (en) * | 1989-07-07 | 1994-09-27 | Pfizer Inc | Heteroaryl piperazine antipsychotic agents |
| AU645681B2 (en) * | 1991-05-02 | 1994-01-20 | John Wyeth & Brother Limited | Piperazine derivatives |
| US5206366A (en) * | 1992-08-26 | 1993-04-27 | Pfizer Inc. | Process for preparing aryl piperazinyl-heterocyclic compounds |
| FR2699918B1 (fr) * | 1992-12-30 | 1995-03-17 | Pf Medicament | Ligands sélectifs des récepteurs 5HY1D-5HT1B dérivés d'indole-pipérazine utiles comme médicaments. |
| US5945422A (en) * | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
| DE19747063A1 (de) * | 1997-10-24 | 1999-04-29 | Basf Ag | 3-substituierte Tetrahydropyridopyrimidinon-Derivate, ihre Herstellung und Verwendung |
| US7160888B2 (en) * | 2003-08-22 | 2007-01-09 | Warner Lambert Company Llc | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia |
-
2006
- 2006-03-20 JP JP2008503619A patent/JP4109709B1/ja not_active Expired - Fee Related
- 2006-03-20 AU AU2006228426A patent/AU2006228426A1/en not_active Abandoned
- 2006-03-20 EP EP06727493A patent/EP1869041A1/en not_active Withdrawn
- 2006-03-20 MX MX2007012083A patent/MX2007012083A/es unknown
- 2006-03-20 AP AP2007004160A patent/AP2007004160A0/xx unknown
- 2006-03-20 CN CNA2006800197403A patent/CN101189237A/zh active Pending
- 2006-03-20 CA CA002603049A patent/CA2603049A1/en not_active Abandoned
- 2006-03-20 EA EA200701856A patent/EA200701856A1/ru unknown
- 2006-03-20 KR KR1020077022373A patent/KR20070112228A/ko not_active Application Discontinuation
- 2006-03-20 WO PCT/IB2006/000900 patent/WO2006103559A1/en active Application Filing
- 2006-03-20 BR BRPI0607918-0A patent/BRPI0607918A2/pt not_active Application Discontinuation
- 2006-03-28 DO DO2006000071A patent/DOP2006000071A/es unknown
- 2006-03-30 AR ARP060101253A patent/AR053835A1/es unknown
- 2006-03-30 UY UY29447A patent/UY29447A1/es not_active Application Discontinuation
- 2006-03-30 PE PE2006000353A patent/PE20061196A1/es not_active Application Discontinuation
- 2006-03-31 TW TW095111562A patent/TW200714282A/zh unknown
- 2006-03-31 US US11/395,931 patent/US20060234997A1/en not_active Abandoned
- 2006-03-31 NL NL1031489A patent/NL1031489C2/nl not_active IP Right Cessation
- 2006-03-31 GT GT200600130A patent/GT200600130A/es unknown
-
2007
- 2007-03-20 NL NL1033562A patent/NL1033562C2/nl not_active IP Right Cessation
- 2007-09-06 IL IL185770A patent/IL185770A0/en unknown
- 2007-09-18 ZA ZA200708033A patent/ZA200708033B/xx unknown
- 2007-09-28 TN TNP2007000366A patent/TNSN07366A1/fr unknown
- 2007-10-01 CR CR9407A patent/CR9407A/es not_active Application Discontinuation
- 2007-10-01 MA MA30264A patent/MA29989B1/fr unknown
- 2007-10-30 NO NO20075477A patent/NO20075477L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2603049A1 (en) | 2006-10-05 |
| KR20070112228A (ko) | 2007-11-22 |
| JP2008534574A (ja) | 2008-08-28 |
| MA29989B1 (fr) | 2008-12-01 |
| US20060234997A1 (en) | 2006-10-19 |
| IL185770A0 (en) | 2008-01-06 |
| EP1869041A1 (en) | 2007-12-26 |
| JP4109709B1 (ja) | 2008-07-02 |
| NO20075477L (no) | 2007-12-13 |
| GT200600130A (es) | 2007-02-14 |
| WO2006103559A1 (en) | 2006-10-05 |
| NL1033562A1 (nl) | 2007-06-21 |
| NL1033562C2 (nl) | 2007-10-23 |
| AR053835A1 (es) | 2007-05-23 |
| NL1031489A1 (nl) | 2006-10-03 |
| TNSN07366A1 (fr) | 2008-12-31 |
| EA200701856A1 (ru) | 2008-02-28 |
| TW200714282A (en) | 2007-04-16 |
| BRPI0607918A2 (pt) | 2009-10-20 |
| AU2006228426A1 (en) | 2006-10-05 |
| CR9407A (es) | 2008-01-29 |
| CN101189237A (zh) | 2008-05-28 |
| ZA200708033B (en) | 2008-11-26 |
| MX2007012083A (es) | 2007-11-20 |
| PE20061196A1 (es) | 2006-12-16 |
| DOP2006000071A (es) | 2006-10-15 |
| NL1031489C2 (nl) | 2007-04-02 |
| UY29447A1 (es) | 2006-10-31 |
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