PE20040121A1 - Formulaciones farmaceuticas de liberacion controlada del 5,8,14-triazatetraciclo [10.3.1.02,11.04.9]-hexadeca-2-(11),3,5,7,9-pentaeno - Google Patents

Formulaciones farmaceuticas de liberacion controlada del 5,8,14-triazatetraciclo [10.3.1.02,11.04.9]-hexadeca-2-(11),3,5,7,9-pentaeno

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Publication number
PE20040121A1
PE20040121A1 PE2002001135A PE2002001135A PE20040121A1 PE 20040121 A1 PE20040121 A1 PE 20040121A1 PE 2002001135 A PE2002001135 A PE 2002001135A PE 2002001135 A PE2002001135 A PE 2002001135A PE 20040121 A1 PE20040121 A1 PE 20040121A1
Authority
PE
Peru
Prior art keywords
matrix
triazatetraciclo
pentaene
hexadeca
controlled release
Prior art date
Application number
PE2002001135A
Other languages
English (en)
Inventor
Ende Mary Tanya Am
Michael Christopher Roy
Scott Wendell Smith
Ernest Shing Quan
Sara Kristen Moses
Kenneth Craig Waterman
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PE20040121A1 publication Critical patent/PE20040121A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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Abstract

SE REFIERE a: UNA FORMA DE DOSIFICACION DE LIBERACION CONTROLADA PARA LA ADMINISTRACION DE 5,8,14-TRIAZATETRACICLO[10.3.1.0(2,11).0(4,9)]-HEXADECA-2(11),3,5,7,9-PENTAENO,TAMBIEN CONOCIDO COMO 7,8,9,10-TETRAHIDRO-6,10-METANO-6H-PIRAZINO[2,3-h][3]-BENZAZEPINA O SU SAL TARTRATO O CITRATO LIBERANDOSE A UNA VELOCIDAD DE MENOS DE ALREDEDOR 6 MG/HORA, SU MEDIO DE ADMINISTRACION COMPRENDE UN COMPRIMIDO RECUBIERTO, COMPRIMIDO MATRIZ, MULTIPARTICULADO MATRIZ O MULTIPARTICULADO RECUBIERTO MATRIZ, PUDIENDO SER LA MATRIZ HIDROFILA. b: UNA FORMA DE DOSIFICACION DE LIBERACION INMEDIATA, CON UN NIVEL TOTAL DE CARBOHIDRATOS REDUCTORES MENOR DE UN 20% EN PESO,DE PREFERENCIA COMPRENDE UN 77-91% DE EXCIPIENTE COMO MANITOL, SORBITOL, CELULOSA MICROCRISTALINA, ALMIDON, FOSFATO DICALCICO BASICO, ENTRE OTROS.LA FORMULACION PUEDE SER UTIL PARA REDUCIR LA ADICION A LA NICOTINA O AYUDAR EN EL CESE O REDUCCION DEL USO DEL TABACO EN TANTO QUE SE REDUCEN LAS NAUSEAS COMO EFECTO ADVERSO,O PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS EN EL INTESTINO, COLITIS ULCEROSA, PIODERMIA GANGRENOSA, ENFERMEDAD DE CROHN, SINDROME DE INTESTINO IRRITABLE, DISTONIA ESPASTICA.
PE2002001135A 2001-11-30 2002-11-26 Formulaciones farmaceuticas de liberacion controlada del 5,8,14-triazatetraciclo [10.3.1.02,11.04.9]-hexadeca-2-(11),3,5,7,9-pentaeno PE20040121A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33465201P 2001-11-30 2001-11-30

Publications (1)

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PE20040121A1 true PE20040121A1 (es) 2004-03-22

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PE2002001135A PE20040121A1 (es) 2001-11-30 2002-11-26 Formulaciones farmaceuticas de liberacion controlada del 5,8,14-triazatetraciclo [10.3.1.02,11.04.9]-hexadeca-2-(11),3,5,7,9-pentaeno

Country Status (30)

Country Link
US (1) US7771748B2 (es)
EP (1) EP1448235B1 (es)
JP (2) JP2005528330A (es)
KR (2) KR100892517B1 (es)
CN (2) CN1596128A (es)
AR (1) AR037592A1 (es)
AT (1) ATE356625T1 (es)
AU (1) AU2002351008B2 (es)
BR (1) BR0214806A (es)
CA (1) CA2467490C (es)
DE (1) DE60218885T2 (es)
DK (1) DK1448235T3 (es)
ES (1) ES2282492T3 (es)
GT (1) GT200200247A (es)
IL (1) IL161857A0 (es)
MX (1) MXPA04003807A (es)
MY (1) MY130619A (es)
NO (1) NO20042739L (es)
NZ (1) NZ532435A (es)
PA (1) PA8559501A1 (es)
PE (1) PE20040121A1 (es)
PL (1) PL208080B1 (es)
PT (1) PT1448235E (es)
RU (2) RU2272629C2 (es)
SI (1) SI1448235T1 (es)
SV (1) SV2004001418A (es)
TW (1) TWI327471B (es)
UY (1) UY27553A1 (es)
WO (1) WO2003045437A1 (es)
ZA (1) ZA200403068B (es)

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