PE20020758A1 - Metodo de fabricacion de vacuna combinada - Google Patents
Metodo de fabricacion de vacuna combinadaInfo
- Publication number
- PE20020758A1 PE20020758A1 PE2002000008A PE2002000008A PE20020758A1 PE 20020758 A1 PE20020758 A1 PE 20020758A1 PE 2002000008 A PE2002000008 A PE 2002000008A PE 2002000008 A PE2002000008 A PE 2002000008A PE 20020758 A1 PE20020758 A1 PE 20020758A1
- Authority
- PE
- Peru
- Prior art keywords
- antigen
- combined vaccine
- manufacturing
- tetano
- diphtheria
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
- A61K39/0017—Combination vaccines based on whole cell diphtheria-tetanus-pertussis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
- A61K39/0018—Combination vaccines based on acellular diphtheria-tetanus-pertussis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
SE REFIERE A UN METODO DE FABRICACION DE UNA VACUNA COMBINADA QUE COMPRENDE LOS PASOS DE: a) ABSORCION QUE PERMITE ADSORBER INDEPENDIENTEMENTE CADA ANTIGENO PROTECTIVO AL ADSORBENTE RESPECTIVO DE DIFERENTES ENFERMEDADES DE MANERA INDEPENDIENTE UN ABSORBENTE COMO GEL DE HIDROXIDO DE ALUMINIO Y b) COMBINACION DE CADA ANTIGENO ABSORBIDO CON EL ADSORBENTE. EL ANTIGENO SE SELECCIONA DE DIFTERIA, TETANO, ANTIGENO DE TOS CONVULSIVA, ANTIGENO DE HEPATITIS B. LA CONCENTRACION DEL ION DE ALUMINIO DESPUES DE LA ELABORACION ESTA ENTRE 0.5 mg/ml Y 1.25 mg/ml. LA PREPARACION COMPRENDE ADEMAS ANADIR UN SURFACTANTE NEUTRAL COMO POLISORBATO 20, POLISORBATO 80 Y TRITON X-100. LA VACUNA COMBINADA ES CAPAZ DE PREVENIR SIMULTANEAMENTE MULTIPLES ENFERMEDADES COMO DIFTERIA, TETANO, TOS CONVULSIVA, HEPATITIS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2001-0001290A KR100401423B1 (ko) | 2001-01-10 | 2001-01-10 | 혼합 백신의 제조 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20020758A1 true PE20020758A1 (es) | 2002-08-29 |
Family
ID=19704448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2002000008A PE20020758A1 (es) | 2001-01-10 | 2002-01-09 | Metodo de fabricacion de vacuna combinada |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20040048336A1 (es) |
| EP (1) | EP1349572B1 (es) |
| JP (1) | JP3977257B2 (es) |
| KR (1) | KR100401423B1 (es) |
| CN (1) | CN1228086C (es) |
| AR (1) | AR032391A1 (es) |
| AT (1) | ATE373485T1 (es) |
| AU (1) | AU2002219693B2 (es) |
| BR (1) | BR0206391A (es) |
| CA (1) | CA2434421C (es) |
| DE (1) | DE60222529T2 (es) |
| ES (1) | ES2291466T3 (es) |
| IL (1) | IL156791A0 (es) |
| MX (1) | MXPA03006154A (es) |
| MY (1) | MY143688A (es) |
| PE (1) | PE20020758A1 (es) |
| PL (1) | PL211005B1 (es) |
| RU (1) | RU2264226C2 (es) |
| UY (1) | UY27118A1 (es) |
| WO (1) | WO2002055105A1 (es) |
| ZA (1) | ZA200305072B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2118963T3 (es) | 1992-05-23 | 1998-10-01 | Smithkline Beecham Biolog | Vacunas combinadas, que contienen antigeno de superficie de la hepatitis b y otros antigenos. |
| GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
| GB0522765D0 (en) | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
| WO2007138621A1 (en) * | 2006-05-31 | 2007-12-06 | Silvio Buzzi | Pharmaceutical use of protein molecules immunologically correlated to diphtheria toxin |
| GB0616306D0 (en) * | 2006-08-16 | 2006-09-27 | Novartis Ag | Vaccines |
| PL2097102T3 (pl) * | 2006-09-07 | 2012-10-31 | Glaxosmithkline Biologicals Sa | Szczepionka skojarzona o zmniejszonej ilości antygenu wirusa polio |
| GB0822633D0 (en) * | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
| IT1398927B1 (it) | 2009-06-25 | 2013-03-28 | Consorzio Interuniversitario Per Lo Sviluppo Dei Sistemi A Grande Interfase Csgi | Espressione batterica di un gene artificiale per la produzione di crm197 e derivati. |
| GB0917647D0 (en) | 2009-10-08 | 2009-11-25 | Glaxosmithkline Biolog Sa | Expression system |
| CN102363041A (zh) * | 2011-11-17 | 2012-02-29 | 成都欧林生物科技股份有限公司 | 不含防腐剂疫苗的制作工艺 |
| KR101518473B1 (ko) | 2013-03-14 | 2015-05-07 | (주)바이오인디스트 | 애완견의 바이러스성 전염병 예방 및 치료용 복합 난황 항체 조성물 및 그 제조방법 |
| AU2015252119A1 (en) | 2014-11-07 | 2016-05-26 | Takeda Vaccines, Inc. | Hand, foot, and mouth vaccines and methods of manufacture and use thereof |
| MA40920A (fr) * | 2014-11-07 | 2017-09-12 | Takeda Vaccines Inc | Vaccins de la main, du pied et de la bouche, et procédés de fabrication et d'utilisation de ceux-ci |
| KR20220076405A (ko) * | 2020-11-30 | 2022-06-08 | 주식회사 엘지화학 | 알루미늄 부형제를 이용하여 다가 혼합백신 내 백일해 균 유래 엔도톡신 제거 방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU188847B (en) * | 1983-02-22 | 1986-05-28 | Human Oltoanyagtermeloe Es Kutato Intezet,Hu | Process for producing liophylized combined vaccines |
| CA1213234A (en) * | 1983-03-30 | 1986-10-28 | Akihiro Ginnaga | Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine |
| US4649192A (en) * | 1985-05-30 | 1987-03-10 | Smith Kline-Rit | Method for the isolation and purification of hepatitis B surface antigen using polysorbate |
| CA1338800C (en) * | 1986-06-17 | 1996-12-17 | Michael Houghton | Hepatitis delta and diagnostics and vaccines |
| JPH085804B2 (ja) * | 1988-04-28 | 1996-01-24 | 財団法人化学及血清療法研究所 | Ａ型及びｂ型肝炎混合アジュバントワクチン |
| EP0484621A3 (en) * | 1990-07-11 | 1992-08-26 | American Cyanamid Company | Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens |
| ES2118963T3 (es) * | 1992-05-23 | 1998-10-01 | Smithkline Beecham Biolog | Vacunas combinadas, que contienen antigeno de superficie de la hepatitis b y otros antigenos. |
| JP4229341B2 (ja) * | 1996-03-23 | 2009-02-25 | 財団法人阪大微生物病研究会 | 破傷風毒素の機能的フラグメント抗原及び破傷風ワクチン |
| GB9611501D0 (en) * | 1996-06-03 | 1996-08-07 | Smithkline Beecham Biolog | Vaccine compositions |
| JP3280675B2 (ja) * | 1996-07-02 | 2002-05-13 | コノート ラボラトリーズ リミテッド | 多価ｄｔｐポリオワクチン |
| GB9623233D0 (en) * | 1996-11-07 | 1997-01-08 | Smithkline Beecham Biolog | Vaccine composition |
| DE69735191T2 (de) * | 1997-09-15 | 2006-10-05 | Sanofi Pasteur Msd | Verfahren zur Herstellung multivalenter Impfstoffe |
| GB9806456D0 (en) * | 1998-03-25 | 1998-05-27 | Smithkline Beecham Biolog | Vaccine composition |
-
2001
- 2001-01-10 KR KR10-2001-0001290A patent/KR100401423B1/ko active IP Right Grant
-
2002
- 2002-01-08 MY MYPI20020056A patent/MY143688A/en unknown
- 2002-01-09 WO PCT/KR2002/000034 patent/WO2002055105A1/en active IP Right Grant
- 2002-01-09 ES ES02729589T patent/ES2291466T3/es not_active Expired - Lifetime
- 2002-01-09 JP JP2002555838A patent/JP3977257B2/ja not_active Expired - Fee Related
- 2002-01-09 EP EP02729589A patent/EP1349572B1/en not_active Revoked
- 2002-01-09 US US10/465,930 patent/US20040048336A1/en not_active Abandoned
- 2002-01-09 CA CA2434421A patent/CA2434421C/en not_active Expired - Fee Related
- 2002-01-09 AU AU2002219693A patent/AU2002219693B2/en not_active Ceased
- 2002-01-09 UY UY27118A patent/UY27118A1/es not_active IP Right Cessation
- 2002-01-09 BR BR0206391-3A patent/BR0206391A/pt active Search and Examination
- 2002-01-09 DE DE60222529T patent/DE60222529T2/de not_active Revoked
- 2002-01-09 RU RU2003124660/15A patent/RU2264226C2/ru active
- 2002-01-09 MX MXPA03006154A patent/MXPA03006154A/es active IP Right Grant
- 2002-01-09 PL PL369433A patent/PL211005B1/pl not_active IP Right Cessation
- 2002-01-09 AT AT02729589T patent/ATE373485T1/de not_active IP Right Cessation
- 2002-01-09 CN CNB028035933A patent/CN1228086C/zh not_active Expired - Fee Related
- 2002-01-09 PE PE2002000008A patent/PE20020758A1/es active IP Right Grant
- 2002-01-09 AR ARP020100060A patent/AR032391A1/es unknown
-
2003
- 2003-01-09 IL IL15679103A patent/IL156791A0/xx not_active IP Right Cessation
- 2003-06-30 ZA ZA200305072A patent/ZA200305072B/en unknown
-
2009
- 2009-03-19 US US12/407,445 patent/US20090181050A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1349572B1 (en) | 2007-09-19 |
| US20090181050A1 (en) | 2009-07-16 |
| ES2291466T3 (es) | 2008-03-01 |
| CN1228086C (zh) | 2005-11-23 |
| WO2002055105A1 (en) | 2002-07-18 |
| ATE373485T1 (de) | 2007-10-15 |
| CN1484531A (zh) | 2004-03-24 |
| UY27118A1 (es) | 2002-08-30 |
| KR100401423B1 (ko) | 2003-10-17 |
| CA2434421C (en) | 2012-02-21 |
| AR032391A1 (es) | 2003-11-05 |
| BR0206391A (pt) | 2004-07-27 |
| DE60222529D1 (de) | 2007-10-31 |
| EP1349572A1 (en) | 2003-10-08 |
| MXPA03006154A (es) | 2003-09-16 |
| DE60222529T2 (de) | 2008-06-19 |
| MY143688A (en) | 2011-06-30 |
| IL156791A0 (en) | 2004-02-08 |
| RU2264226C2 (ru) | 2005-11-20 |
| ZA200305072B (en) | 2003-09-17 |
| PL211005B1 (pl) | 2012-03-30 |
| KR20020060298A (ko) | 2002-07-18 |
| JP3977257B2 (ja) | 2007-09-19 |
| CA2434421A1 (en) | 2002-07-18 |
| AU2002219693B2 (en) | 2006-03-16 |
| RU2003124660A (ru) | 2005-01-10 |
| JP2004517866A (ja) | 2004-06-17 |
| US20040048336A1 (en) | 2004-03-11 |
| PL369433A1 (en) | 2005-04-18 |
| EP1349572A4 (en) | 2004-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |