BR0206391A - Método para a fabricação de uma vacina combinada - Google Patents
Método para a fabricação de uma vacina combinadaInfo
- Publication number
- BR0206391A BR0206391A BR0206391-3A BR0206391A BR0206391A BR 0206391 A BR0206391 A BR 0206391A BR 0206391 A BR0206391 A BR 0206391A BR 0206391 A BR0206391 A BR 0206391A
- Authority
- BR
- Brazil
- Prior art keywords
- combined vaccine
- present
- diseases
- tetanus
- diphtheria
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
- A61K39/0017—Combination vaccines based on whole cell diphtheria-tetanus-pertussis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
- A61K39/0018—Combination vaccines based on acellular diphtheria-tetanus-pertussis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"MéTODO PARA A FABRICAçãO DE UMA VACINA COMBINADA". A presente invenção refere-se a um método para a fabricação de uma vacina combinada capaz de prevenir de forma concorrente diversas doenças de crianças, tais como difteria, tétano, tosse convulsiva, hepatite B e outras doenças, que devem ser evitadas em crianças. O método para a fabricação da vacina combinada, de acordo com a presente invenção, inclui as etapas de adsorver de forma independente cada um dos antígenos de proteção a um adsorvente de gel de hidróxido de alumínio com relação a diversas doenças, tais como a difteria, tétano, tosse convulsiva e hepatite B que devem ser evitadas em crianças, e combinando cada um dos antígenos de proteção adsorvido ao adsorvente depois da adsorção. Na presente invenção é possível evitar de forma concorrente múltiplas doenças, tais como a difteria, tétano, tosse convulsiva e hepatite B que devem ser evitadas em crianças, com a utilização de uma vacina combinada fabricada de acordo com a presente invenção.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2001-0001290A KR100401423B1 (ko) | 2001-01-10 | 2001-01-10 | 혼합 백신의 제조 방법 |
| PCT/KR2002/000034 WO2002055105A1 (en) | 2001-01-10 | 2002-01-09 | Manufacturing method of combined vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0206391A true BR0206391A (pt) | 2004-07-27 |
Family
ID=19704448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0206391-3A BR0206391A (pt) | 2001-01-10 | 2002-01-09 | Método para a fabricação de uma vacina combinada |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20040048336A1 (pt) |
| EP (1) | EP1349572B1 (pt) |
| JP (1) | JP3977257B2 (pt) |
| KR (1) | KR100401423B1 (pt) |
| CN (1) | CN1228086C (pt) |
| AR (1) | AR032391A1 (pt) |
| AT (1) | ATE373485T1 (pt) |
| AU (1) | AU2002219693B2 (pt) |
| BR (1) | BR0206391A (pt) |
| CA (1) | CA2434421C (pt) |
| DE (1) | DE60222529T2 (pt) |
| ES (1) | ES2291466T3 (pt) |
| IL (1) | IL156791A0 (pt) |
| MX (1) | MXPA03006154A (pt) |
| MY (1) | MY143688A (pt) |
| PE (1) | PE20020758A1 (pt) |
| PL (1) | PL211005B1 (pt) |
| RU (1) | RU2264226C2 (pt) |
| UY (1) | UY27118A1 (pt) |
| WO (1) | WO2002055105A1 (pt) |
| ZA (1) | ZA200305072B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA40596C2 (uk) | 1992-05-23 | 2001-08-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини та спосіб її одержання |
| GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
| GB0522765D0 (en) * | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
| CN101460180B (zh) * | 2006-05-31 | 2012-06-27 | 西尔维奥·布齐 | 与白喉毒素免疫相关的蛋白质分子的药物应用 |
| GB0616306D0 (en) * | 2006-08-16 | 2006-09-27 | Novartis Ag | Vaccines |
| WO2008028957A2 (en) * | 2006-09-07 | 2008-03-13 | Glaxosmithkline Biologicals S.A. | Vaccine |
| GB0822633D0 (en) * | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
| IT1398927B1 (it) | 2009-06-25 | 2013-03-28 | Consorzio Interuniversitario Per Lo Sviluppo Dei Sistemi A Grande Interfase Csgi | Espressione batterica di un gene artificiale per la produzione di crm197 e derivati. |
| GB0917647D0 (en) | 2009-10-08 | 2009-11-25 | Glaxosmithkline Biolog Sa | Expression system |
| CN102363041A (zh) * | 2011-11-17 | 2012-02-29 | 成都欧林生物科技股份有限公司 | 不含防腐剂疫苗的制作工艺 |
| KR101518473B1 (ko) | 2013-03-14 | 2015-05-07 | (주)바이오인디스트 | 애완견의 바이러스성 전염병 예방 및 치료용 복합 난황 항체 조성물 및 그 제조방법 |
| AR102547A1 (es) * | 2014-11-07 | 2017-03-08 | Takeda Vaccines Inc | Vacunas contra la enfermedad de manos, pies y boca y métodos de fabricación y su uso |
| AU2015252119A1 (en) | 2014-11-07 | 2016-05-26 | Takeda Vaccines, Inc. | Hand, foot, and mouth vaccines and methods of manufacture and use thereof |
| KR20220076405A (ko) * | 2020-11-30 | 2022-06-08 | 주식회사 엘지화학 | 알루미늄 부형제를 이용하여 다가 혼합백신 내 백일해 균 유래 엔도톡신 제거 방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU188847B (en) * | 1983-02-22 | 1986-05-28 | Human Oltoanyagtermeloe Es Kutato Intezet,Hu | Process for producing liophylized combined vaccines |
| CA1213234A (en) * | 1983-03-30 | 1986-10-28 | Akihiro Ginnaga | Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine |
| US4649192A (en) * | 1985-05-30 | 1987-03-10 | Smith Kline-Rit | Method for the isolation and purification of hepatitis B surface antigen using polysorbate |
| ES2061500T5 (es) * | 1986-06-17 | 2003-05-16 | Chiron Corp | Diagnosis y vacunas de la hepatitis delta, su preparacion y uso. |
| JPH085804B2 (ja) * | 1988-04-28 | 1996-01-24 | 財団法人化学及血清療法研究所 | Ａ型及びｂ型肝炎混合アジュバントワクチン |
| EP0484621A3 (en) * | 1990-07-11 | 1992-08-26 | American Cyanamid Company | Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens |
| UA40596C2 (uk) * | 1992-05-23 | 2001-08-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини та спосіб її одержання |
| JP4229341B2 (ja) * | 1996-03-23 | 2009-02-25 | 財団法人阪大微生物病研究会 | 破傷風毒素の機能的フラグメント抗原及び破傷風ワクチン |
| GB9611501D0 (en) * | 1996-06-03 | 1996-08-07 | Smithkline Beecham Biolog | Vaccine compositions |
| TR199802783T2 (xx) * | 1996-07-02 | 1999-03-22 | Connaught Laboratories Limited | �ok de�erli DTP polyo a��lar. |
| GB9623233D0 (en) * | 1996-11-07 | 1997-01-08 | Smithkline Beecham Biolog | Vaccine composition |
| DE69735191T2 (de) * | 1997-09-15 | 2006-10-05 | Sanofi Pasteur Msd | Verfahren zur Herstellung multivalenter Impfstoffe |
| GB9806456D0 (en) * | 1998-03-25 | 1998-05-27 | Smithkline Beecham Biolog | Vaccine composition |
-
2001
- 2001-01-10 KR KR10-2001-0001290A patent/KR100401423B1/ko active IP Right Grant
-
2002
- 2002-01-08 MY MYPI20020056A patent/MY143688A/en unknown
- 2002-01-09 CA CA2434421A patent/CA2434421C/en not_active Expired - Fee Related
- 2002-01-09 EP EP02729589A patent/EP1349572B1/en not_active Revoked
- 2002-01-09 RU RU2003124660/15A patent/RU2264226C2/ru active
- 2002-01-09 US US10/465,930 patent/US20040048336A1/en not_active Abandoned
- 2002-01-09 MX MXPA03006154A patent/MXPA03006154A/es active IP Right Grant
- 2002-01-09 PL PL369433A patent/PL211005B1/pl not_active IP Right Cessation
- 2002-01-09 ES ES02729589T patent/ES2291466T3/es not_active Expired - Lifetime
- 2002-01-09 AR ARP020100060A patent/AR032391A1/es unknown
- 2002-01-09 JP JP2002555838A patent/JP3977257B2/ja not_active Expired - Fee Related
- 2002-01-09 UY UY27118A patent/UY27118A1/es not_active IP Right Cessation
- 2002-01-09 AT AT02729589T patent/ATE373485T1/de not_active IP Right Cessation
- 2002-01-09 DE DE60222529T patent/DE60222529T2/de not_active Revoked
- 2002-01-09 PE PE2002000008A patent/PE20020758A1/es active IP Right Grant
- 2002-01-09 WO PCT/KR2002/000034 patent/WO2002055105A1/en active IP Right Grant
- 2002-01-09 AU AU2002219693A patent/AU2002219693B2/en not_active Ceased
- 2002-01-09 BR BR0206391-3A patent/BR0206391A/pt active Search and Examination
- 2002-01-09 CN CNB028035933A patent/CN1228086C/zh not_active Expired - Fee Related
-
2003
- 2003-01-09 IL IL15679103A patent/IL156791A0/xx not_active IP Right Cessation
- 2003-06-30 ZA ZA200305072A patent/ZA200305072B/en unknown
-
2009
- 2009-03-19 US US12/407,445 patent/US20090181050A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA03006154A (es) | 2003-09-16 |
| CN1228086C (zh) | 2005-11-23 |
| ES2291466T3 (es) | 2008-03-01 |
| AR032391A1 (es) | 2003-11-05 |
| RU2264226C2 (ru) | 2005-11-20 |
| KR20020060298A (ko) | 2002-07-18 |
| IL156791A0 (en) | 2004-02-08 |
| AU2002219693B2 (en) | 2006-03-16 |
| PL211005B1 (pl) | 2012-03-30 |
| EP1349572A4 (en) | 2004-09-15 |
| DE60222529T2 (de) | 2008-06-19 |
| ATE373485T1 (de) | 2007-10-15 |
| CA2434421C (en) | 2012-02-21 |
| UY27118A1 (es) | 2002-08-30 |
| ZA200305072B (en) | 2003-09-17 |
| DE60222529D1 (de) | 2007-10-31 |
| PL369433A1 (en) | 2005-04-18 |
| US20090181050A1 (en) | 2009-07-16 |
| US20040048336A1 (en) | 2004-03-11 |
| JP3977257B2 (ja) | 2007-09-19 |
| MY143688A (en) | 2011-06-30 |
| JP2004517866A (ja) | 2004-06-17 |
| RU2003124660A (ru) | 2005-01-10 |
| PE20020758A1 (es) | 2002-08-29 |
| CN1484531A (zh) | 2004-03-24 |
| EP1349572A1 (en) | 2003-10-08 |
| WO2002055105A1 (en) | 2002-07-18 |
| CA2434421A1 (en) | 2002-07-18 |
| KR100401423B1 (ko) | 2003-10-17 |
| EP1349572B1 (en) | 2007-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: LG CHEM, LTD. (KR) |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time |