PE20020500A1 - Derivados de piperidina, tetrahidroquinolina, tetrahidroisoquinolina como inhibidores de caspasas - Google Patents

Derivados de piperidina, tetrahidroquinolina, tetrahidroisoquinolina como inhibidores de caspasas

Info

Publication number
PE20020500A1
PE20020500A1 PE2001000916A PE2001000916A PE20020500A1 PE 20020500 A1 PE20020500 A1 PE 20020500A1 PE 2001000916 A PE2001000916 A PE 2001000916A PE 2001000916 A PE2001000916 A PE 2001000916A PE 20020500 A1 PE20020500 A1 PE 20020500A1
Authority
PE
Peru
Prior art keywords
piperidine
carbonyl
tetrahydroquinoline
tetrahydroisoquinoline
derivatives
Prior art date
Application number
PE2001000916A
Other languages
English (en)
Spanish (es)
Inventor
Jean-Damien Charrier
Ronald Knegtel
Michael Mortimore
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of PE20020500A1 publication Critical patent/PE20020500A1/es

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    • C07—ORGANIC CHEMISTRY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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PE2001000916A 2000-09-13 2001-09-12 Derivados de piperidina, tetrahidroquinolina, tetrahidroisoquinolina como inhibidores de caspasas PE20020500A1 (es)

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US23257300P 2000-09-13 2000-09-13

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PE20020500A1 true PE20020500A1 (es) 2002-06-25

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PE2001000916A PE20020500A1 (es) 2000-09-13 2001-09-12 Derivados de piperidina, tetrahidroquinolina, tetrahidroisoquinolina como inhibidores de caspasas

Country Status (8)

Country Link
US (1) US6800619B2 (OSRAM)
EP (1) EP1317454B1 (OSRAM)
JP (2) JP2004509120A (OSRAM)
AT (1) ATE510837T1 (OSRAM)
AU (1) AU2001290795A1 (OSRAM)
CA (1) CA2418720A1 (OSRAM)
PE (1) PE20020500A1 (OSRAM)
WO (1) WO2002022611A2 (OSRAM)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020058636A1 (en) * 1994-09-21 2002-05-16 Geoffrey P. Symonds Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
EP1317454B1 (en) * 2000-09-13 2011-05-25 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
FR2815541B1 (fr) * 2000-10-24 2008-02-29 Lipha Utilisation d'inhibiteurs de l'apoptose des pericytes pour le traitement et/ou la prevention de la retinopathie diabetique
EP1381602A1 (en) * 2001-04-19 2004-01-21 Vertex Pharmaceuticals Incorporated Heterocyclyldicarbamides as caspase inhibitors
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CA2418720A1 (en) 2002-03-21
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