PE20011308A1 - Composicion que comprende un antihipertensivo y un carboxialquileter util para tratar enfermedades vasculares - Google Patents

Composicion que comprende un antihipertensivo y un carboxialquileter util para tratar enfermedades vasculares

Info

Publication number
PE20011308A1
PE20011308A1 PE2001000363A PE2001000363A PE20011308A1 PE 20011308 A1 PE20011308 A1 PE 20011308A1 PE 2001000363 A PE2001000363 A PE 2001000363A PE 2001000363 A PE2001000363 A PE 2001000363A PE 20011308 A1 PE20011308 A1 PE 20011308A1
Authority
PE
Peru
Prior art keywords
composition
carboxialkyleter
antihypertensive
useful
preference
Prior art date
Application number
PE2001000363A
Other languages
English (en)
Inventor
Bruce Jeffrey Auerbach
Michael John Ryan
Karen Diane Hitchcock
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PE20011308A1 publication Critical patent/PE20011308A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7275Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA COMPOSICION QUE COMPRENDE a)CARBOXIALQUILETER DE FORMULA I; n Y m SON 2-9; R1, R2, R3, R4 SON ALQUILO C1-C6, ALQUENILO C1-C6, ALQUINILO C2-C6 O R1 Y R2 O R3 Y R4 FORMAN CARBOCICLO C3-C6; Y1 E Y2 SON COOH, CHO, TETRAZOL, COOR5; R5 ES ALQUILO C1-C6, ALQUENILO C2-C6, ALQUINILO C2-C6 DE PREFERENCIA ACIDO 6,6'-OXIBIS(2,2-DIMETILHEXANOICO) DE MONOCALCIO; QUE PRODUCE UN AUMENTO DEL COLESTEROL DE LIPOPROTEINA DE ALTA DENSIDAD; b)ANTIHIPERTENSIVO COMO BLOQUEANTE DEL CANAL DE CALCIO, UN INHIBIDOR DE ACE, UN O-BLOQUEANTE, UN ß-BLOQUEANTE; UN AGENTE DIURETICO; DE PREFERENCIA AMLODIPINA, CLORHIDRATO DE QUINALAPRIL; QUE PRODUCE UNA REDUCCION DE LA PRESION SANGUINEA. LA COMPOSICION PUEDE SER UTIL PARA TRATAR TRASTORNOS Y PREVENIR LA INSUFICIENCIA CARDIACA CONGESTIVA; ANGINA, HIPERTENSION, RIESGO CARDIACO, ATEROSCLEROSIS
PE2001000363A 2000-04-26 2001-04-24 Composicion que comprende un antihipertensivo y un carboxialquileter util para tratar enfermedades vasculares PE20011308A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19985500P 2000-04-26 2000-04-26
US24228000P 2000-10-20 2000-10-20

Publications (1)

Publication Number Publication Date
PE20011308A1 true PE20011308A1 (es) 2002-01-18

Family

ID=26895229

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001000363A PE20011308A1 (es) 2000-04-26 2001-04-24 Composicion que comprende un antihipertensivo y un carboxialquileter util para tratar enfermedades vasculares

Country Status (34)

Country Link
EP (1) EP1280522B1 (es)
JP (1) JP2003531170A (es)
KR (1) KR20020091245A (es)
CN (1) CN1426299A (es)
AP (1) AP2002002665A0 (es)
AR (1) AR031104A1 (es)
AT (1) ATE283691T1 (es)
AU (1) AU2001247658A1 (es)
BG (1) BG107264A (es)
BR (1) BR0110234A (es)
CA (1) CA2405559A1 (es)
CZ (1) CZ20023459A3 (es)
DE (1) DE60107559T2 (es)
DO (1) DOP2001000150A (es)
EA (1) EA005245B1 (es)
EE (1) EE200200611A (es)
ES (1) ES2231470T3 (es)
HR (1) HRP20020936A2 (es)
HU (1) HUP0300403A3 (es)
IL (1) IL152474A0 (es)
IS (1) IS6570A (es)
MA (1) MA26894A1 (es)
MX (1) MXPA02009662A (es)
NO (1) NO20025135L (es)
NZ (1) NZ521713A (es)
OA (1) OA12252A (es)
PA (1) PA8516001A1 (es)
PE (1) PE20011308A1 (es)
PL (1) PL357906A1 (es)
PT (1) PT1280522E (es)
SK (1) SK15132002A3 (es)
SV (1) SV2002000367A (es)
TN (1) TNSN01061A1 (es)
WO (1) WO2001080847A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1481962A1 (en) * 1997-12-12 2004-12-01 Warner-Lambert Company LLC New cholesterolemia-lowering carboxyalkylether compound
US8278310B2 (en) * 2007-06-21 2012-10-02 Actimis Pharmaceuticals, Inc. Amine salts of a CRTH2 antagonist
DE102008026033B4 (de) * 2008-05-30 2017-08-24 Voith Patent Gmbh Antriebsstrang mit einer hydrodynamischen Maschine
SI23149A (sl) * 2009-09-21 2011-03-31 Silverstone Pharma Nove benzatinske soli ACE inhibitorjev, postopek za njihovo pripravo in njihova uporaba za zdravljenje kardiovaskularnih bolezni

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298497A (en) * 1990-05-15 1994-03-29 E. R. Squibb & Sons, Inc. Method for preventing onset of hypertension employing a cholesterol lowering drug
US5648387A (en) * 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
NZ503982A (en) * 1997-12-12 2002-03-28 Warner Lambert Co Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus

Also Published As

Publication number Publication date
DE60107559D1 (de) 2005-01-05
MXPA02009662A (es) 2003-03-10
NZ521713A (en) 2004-09-24
ES2231470T3 (es) 2005-05-16
EE200200611A (et) 2004-06-15
DOP2001000150A (es) 2002-08-15
ATE283691T1 (de) 2004-12-15
CN1426299A (zh) 2003-06-25
IS6570A (is) 2002-09-27
AU2001247658A1 (en) 2001-11-07
MA26894A1 (fr) 2004-12-20
BR0110234A (pt) 2003-03-05
PT1280522E (pt) 2005-02-28
WO2001080847A3 (en) 2002-07-18
JP2003531170A (ja) 2003-10-21
OA12252A (en) 2006-05-11
BG107264A (en) 2003-07-31
PA8516001A1 (es) 2002-09-17
SV2002000367A (es) 2002-08-26
CA2405559A1 (en) 2001-11-01
EA200200953A1 (ru) 2003-04-24
AP2002002665A0 (en) 2002-12-31
DE60107559T2 (de) 2005-04-14
NO20025135D0 (no) 2002-10-25
EP1280522A2 (en) 2003-02-05
TNSN01061A1 (en) 2005-11-10
NO20025135L (no) 2002-11-27
PL357906A1 (en) 2004-08-09
EA005245B1 (ru) 2004-12-30
HRP20020936A2 (en) 2004-12-31
AR031104A1 (es) 2003-09-10
EP1280522B1 (en) 2004-12-01
SK15132002A3 (sk) 2003-08-05
KR20020091245A (ko) 2002-12-05
HUP0300403A2 (hu) 2003-06-28
WO2001080847A2 (en) 2001-11-01
HUP0300403A3 (en) 2005-03-29
IL152474A0 (en) 2003-05-29
CZ20023459A3 (cs) 2003-05-14

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