PE20001558A1 - Composiciones analgesicas que comprenden compuestos antiepilepticos - Google Patents

Composiciones analgesicas que comprenden compuestos antiepilepticos

Info

Publication number
PE20001558A1
PE20001558A1 PE2000000204A PE0002042000A PE20001558A1 PE 20001558 A1 PE20001558 A1 PE 20001558A1 PE 2000000204 A PE2000000204 A PE 2000000204A PE 0002042000 A PE0002042000 A PE 0002042000A PE 20001558 A1 PE20001558 A1 PE 20001558A1
Authority
PE
Peru
Prior art keywords
methyl
compositions including
analgesic compositions
antiepileptic compounds
alkyl
Prior art date
Application number
PE2000000204A
Other languages
English (en)
Inventor
Trevor Mundel
Mark Richard Hurtt
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PE20001558A1 publication Critical patent/PE20001558A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA COMBINACION DE i)UN COMPUESTO ANTIEPILEPTICO DE FORMULA I, DONDE: R1 ES H, ALQUILO, n ES 4-6, EL ANILLO CICLICO ES OPCIONALMENTE SUSTITUIDO; (H2N)(R13)-CH-C(R12)(R11)-CH2COOH, R11 ES ALQUILO C1-C6, FENILO, CICLOALQUILO C3-C6, R12 ES H, METILO; R13 ES H, METILO, CARBOXILO, O GABAPENTINA, PREGABALINA, ii)AL MENOS UNO O COMBINACIONES DE a)UN ANTAGONISTA DEL RECEPTOR N-METIL-D-ASPARTATO (NMDA); b)ANALGESICOS NO ESTEROIDEOS TAL COMO NAPROXENO, c)UN ANALGESICO NARCOTICO TAL COMO MORFINA. LA COMBINACION PUEDE SER UTIL PARA TRATAR EL DOLOR
PE2000000204A 1999-03-10 2000-03-08 Composiciones analgesicas que comprenden compuestos antiepilepticos PE20001558A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12373999P 1999-03-10 1999-03-10

Publications (1)

Publication Number Publication Date
PE20001558A1 true PE20001558A1 (es) 2001-01-28

Family

ID=22410582

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000000204A PE20001558A1 (es) 1999-03-10 2000-03-08 Composiciones analgesicas que comprenden compuestos antiepilepticos

Country Status (11)

Country Link
US (1) US6451857B1 (es)
EP (1) EP1161263A1 (es)
JP (1) JP2002538221A (es)
AR (1) AR022723A1 (es)
AU (1) AU3216600A (es)
BR (1) BR0008847A (es)
CA (1) CA2359485A1 (es)
CO (1) CO5150189A1 (es)
PE (1) PE20001558A1 (es)
UY (1) UY26052A1 (es)
WO (1) WO2000053225A1 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998003167A1 (en) 1996-07-24 1998-01-29 Warner-Lambert Company Isobutylgaba and its derivatives for the treatment of pain
ATE311867T1 (de) 1997-09-08 2005-12-15 Warner Lambert Co Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen
CA2373953A1 (en) * 1999-07-02 2001-01-11 Warner-Lambert Company A synergistic combination: gabapentin and pregabalin
ZA200108038B (en) * 2000-10-02 2003-04-01 Pfizer Prod Inc Prophylactic use of n-methyl-d-asparrate (NMDA) antagonists.
US8309570B2 (en) 2001-06-07 2012-11-13 Analgesic Neuropharmaceuticals, Llc Treatment of central neuropathic pain
MXPA04002009A (es) 2001-09-03 2004-07-08 Newron Pharm Spa Composicion farmaceutica que comprende gabapentina o un analogo de la misma y alfa-aminoamida y su uso como analgesico.
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US6730667B2 (en) * 2001-11-26 2004-05-04 William R. Deagle Iontophoresis disc pain blocker
CA2473536A1 (en) * 2002-01-16 2003-07-31 Endo Pharmaceuticals, Inc. Pharmaceutical composition and method for treating disorders of the central nervous system
JP4428053B2 (ja) * 2002-02-05 2010-03-10 味の素株式会社 ガバペンチン若しくはプレガバリンおよびｎ型カルシウムチャンネル拮抗剤を含有する医薬組成物
RU2286151C2 (ru) * 2002-02-22 2006-10-27 Уорнер-Ламберт Компани Ллс Комбинации альфа-2-дельта-лиганда с селективным ингибитором циклооксигеназы-2
US7799832B2 (en) 2003-10-23 2010-09-21 Valeant Pharmaceuticals North America Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
FR2862875B1 (fr) * 2003-12-02 2006-04-07 Mathey Acoustique Service Preparation pharmaceutique pour le traitement des acouphenes
WO2005102390A2 (en) * 2004-04-22 2005-11-03 Pfizer Japan, Inc. Combinations comprising alpha-2-delta ligands and nmda receptor antagonists
ES2556937T3 (es) 2005-12-22 2016-01-21 Newron Pharmaceuticals S.P.A. Derivados de 2-feniletilamino como moduladores de los canales de calcio y/o sodio
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
US7960436B2 (en) * 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
SG174095A1 (en) * 2006-08-23 2011-09-29 Valeant Pharmaceuticals Int Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
BRPI0719590A2 (pt) * 2006-11-28 2014-01-21 Valeant Pharmaceuticals Int Análogos de retigabina 1,4 diamino bicíclica como modulares de canal de potássio
MX2009006575A (es) * 2006-12-22 2009-07-02 Recordati Ireland Ltd Terapia de combinacion de trastornos del tracto urinario inferior con ligandos a2d y farmacos anti-inflamatorios no esteroidales (nsaids).
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
EP2116539A1 (en) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
JP2010043063A (ja) 2008-05-09 2010-02-25 Agency For Science Technology & Research 川崎病の診断及び治療
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
AU2009296457A1 (en) 2008-09-27 2010-04-01 Taraxos Inc. Topical formulations for treatment of neuropathy
CN105330603A (zh) 2008-10-08 2016-02-17 凯飞药业公司 Gaba偶联物及其使用方法
AU2014364647A1 (en) 2013-12-17 2016-06-23 Laboratorios Del Dr. Esteve, S.A. Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) and Sigma receptor ligands combinations
MA39146A1 (fr) * 2013-12-17 2017-11-30 Esteve Labor Dr Combinaisons de gabapentanoïdes et de ligands des récepteurs sigma
CA2951987C (en) 2014-06-16 2017-10-24 Farmaceuticos Rayere, S.A. Pharmaceutical composition that combines an anticonvulsant and a nicotinic acid derivative
MX2015016589A (es) 2015-12-02 2017-06-01 Samuel CHAIT AUERBACH Jaime Composicion oral veterinaria con gabapentina.
US10874626B2 (en) * 2016-04-07 2020-12-29 Nevakar Inc. Formulation for use in a method of treatment of pain
WO2017200700A1 (en) * 2016-05-16 2017-11-23 PixarBio Corporation Methods for treating incisional pain
WO2019067768A2 (en) * 2017-09-28 2019-04-04 Nevakar, Inc. FIXED DOSE COMBINATION FORMULATIONS FOR THE TREATMENT OF PAIN
EP3691748A4 (en) 2017-10-03 2021-07-07 Nevakar, Inc ACETAMINOPHEN-PREGABALIN COMBINATIONS AND METHODS OF TREATMENT OF PAIN

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4694010A (en) 1985-08-16 1987-09-15 New York University Anticonvulsant compositions and method
AU4078897A (en) * 1996-08-23 1998-03-06 Algos Pharmaceutical Corporation Anticonvulsant containing composition for treating neuropathic pain
AU8668598A (en) * 1997-08-20 1999-03-08 University Of Oklahoma, The Gaba analogs to prevent and treat gastrointestinal damage
ATE311867T1 (de) * 1997-09-08 2005-12-15 Warner Lambert Co Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen

Also Published As

Publication number Publication date
CO5150189A1 (es) 2002-04-29
EP1161263A1 (en) 2001-12-12
JP2002538221A (ja) 2002-11-12
UY26052A1 (es) 2000-08-21
US6451857B1 (en) 2002-09-17
CA2359485A1 (en) 2000-09-14
AR022723A1 (es) 2002-09-04
BR0008847A (pt) 2001-12-26
AU3216600A (en) 2000-09-28
WO2000053225A1 (en) 2000-09-14

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