CO5150189A1 - Composiciones analgesicas que comprenden compuestos antiepilepticos y metodos para usarlas - Google Patents
Composiciones analgesicas que comprenden compuestos antiepilepticos y metodos para usarlasInfo
- Publication number
- CO5150189A1 CO5150189A1 CO00016924A CO00016924A CO5150189A1 CO 5150189 A1 CO5150189 A1 CO 5150189A1 CO 00016924 A CO00016924 A CO 00016924A CO 00016924 A CO00016924 A CO 00016924A CO 5150189 A1 CO5150189 A1 CO 5150189A1
- Authority
- CO
- Colombia
- Prior art keywords
- methods
- effective amount
- analgesic compositions
- antiepileptic compounds
- compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una combinación de una cantidad efectiva de al menos un compuesto antiepiléptico con propiedades que alivian el dolor seleccionados entre gabapentina, pregabalina, carbamazepina, lamotrogina, fenitoína, fosfenitoina y análogos de los mismos, y una cantidad efectiva de al menos un compuesto seleccionado del grupo que consiste en antagonistas del receptor de N-metil-D-aspartato (NMDA), seleccionado entre dextrorfán, dextrometorfán, ketamina, ifenprodil, (15,25)-1-(4-hidroxifenil)2-(4-hidroxi-4-fenilpiperidina)-1-propanol, drogas antiinflamatorias no esteroides (NSAID) seleccionadas entre naproxeno, ibuprofeno, naprosin, diclorofenac, ketofreno, tolmetina, sulindac y análogos.<EMI FILE="00016924_1" ID="1" IMF=JPEG >
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12373999P | 1999-03-10 | 1999-03-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5150189A1 true CO5150189A1 (es) | 2002-04-29 |
Family
ID=22410582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO00016924A CO5150189A1 (es) | 1999-03-10 | 2000-03-08 | Composiciones analgesicas que comprenden compuestos antiepilepticos y metodos para usarlas |
Country Status (11)
Country | Link |
---|---|
US (1) | US6451857B1 (es) |
EP (1) | EP1161263A1 (es) |
JP (1) | JP2002538221A (es) |
AR (1) | AR022723A1 (es) |
AU (1) | AU3216600A (es) |
BR (1) | BR0008847A (es) |
CA (1) | CA2359485A1 (es) |
CO (1) | CO5150189A1 (es) |
PE (1) | PE20001558A1 (es) |
UY (1) | UY26052A1 (es) |
WO (1) | WO2000053225A1 (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998003167A1 (en) | 1996-07-24 | 1998-01-29 | Warner-Lambert Company | Isobutylgaba and its derivatives for the treatment of pain |
ATE311867T1 (de) | 1997-09-08 | 2005-12-15 | Warner Lambert Co | Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen |
CA2373953A1 (en) * | 1999-07-02 | 2001-01-11 | Warner-Lambert Company | A synergistic combination: gabapentin and pregabalin |
ZA200108038B (en) * | 2000-10-02 | 2003-04-01 | Pfizer Prod Inc | Prophylactic use of n-methyl-d-asparrate (NMDA) antagonists. |
US8309570B2 (en) | 2001-06-07 | 2012-11-13 | Analgesic Neuropharmaceuticals, Llc | Treatment of central neuropathic pain |
MXPA04002009A (es) | 2001-09-03 | 2004-07-08 | Newron Pharm Spa | Composicion farmaceutica que comprende gabapentina o un analogo de la misma y alfa-aminoamida y su uso como analgesico. |
TWI312285B (en) | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
US7612112B2 (en) | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
US6730667B2 (en) * | 2001-11-26 | 2004-05-04 | William R. Deagle | Iontophoresis disc pain blocker |
CA2473536A1 (en) * | 2002-01-16 | 2003-07-31 | Endo Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating disorders of the central nervous system |
JP4428053B2 (ja) * | 2002-02-05 | 2010-03-10 | 味の素株式会社 | ガバペンチン若しくはプレガバリンおよびn型カルシウムチャンネル拮抗剤を含有する医薬組成物 |
RU2286151C2 (ru) * | 2002-02-22 | 2006-10-27 | Уорнер-Ламберт Компани Ллс | Комбинации альфа-2-дельта-лиганда с селективным ингибитором циклооксигеназы-2 |
US7799832B2 (en) | 2003-10-23 | 2010-09-21 | Valeant Pharmaceuticals North America | Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
FR2862875B1 (fr) * | 2003-12-02 | 2006-04-07 | Mathey Acoustique Service | Preparation pharmaceutique pour le traitement des acouphenes |
WO2005102390A2 (en) * | 2004-04-22 | 2005-11-03 | Pfizer Japan, Inc. | Combinations comprising alpha-2-delta ligands and nmda receptor antagonists |
ES2556937T3 (es) | 2005-12-22 | 2016-01-21 | Newron Pharmaceuticals S.P.A. | Derivados de 2-feniletilamino como moduladores de los canales de calcio y/o sodio |
US20090176882A1 (en) | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
US7960436B2 (en) * | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
SG174095A1 (en) * | 2006-08-23 | 2011-09-29 | Valeant Pharmaceuticals Int | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
US8993593B2 (en) * | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
BRPI0719590A2 (pt) * | 2006-11-28 | 2014-01-21 | Valeant Pharmaceuticals Int | Análogos de retigabina 1,4 diamino bicíclica como modulares de canal de potássio |
MX2009006575A (es) * | 2006-12-22 | 2009-07-02 | Recordati Ireland Ltd | Terapia de combinacion de trastornos del tracto urinario inferior con ligandos a2d y farmacos anti-inflamatorios no esteroidales (nsaids). |
US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
US8563566B2 (en) * | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
EP2116539A1 (en) | 2008-04-25 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof |
JP2010043063A (ja) | 2008-05-09 | 2010-02-25 | Agency For Science Technology & Research | 川崎病の診断及び治療 |
US20100190752A1 (en) | 2008-09-05 | 2010-07-29 | Gruenenthal Gmbh | Pharmaceutical Combination |
AU2009296457A1 (en) | 2008-09-27 | 2010-04-01 | Taraxos Inc. | Topical formulations for treatment of neuropathy |
CN105330603A (zh) | 2008-10-08 | 2016-02-17 | 凯飞药业公司 | Gaba偶联物及其使用方法 |
AU2014364647A1 (en) | 2013-12-17 | 2016-06-23 | Laboratorios Del Dr. Esteve, S.A. | Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) and Sigma receptor ligands combinations |
MA39146A1 (fr) * | 2013-12-17 | 2017-11-30 | Esteve Labor Dr | Combinaisons de gabapentanoïdes et de ligands des récepteurs sigma |
CA2951987C (en) | 2014-06-16 | 2017-10-24 | Farmaceuticos Rayere, S.A. | Pharmaceutical composition that combines an anticonvulsant and a nicotinic acid derivative |
MX2015016589A (es) | 2015-12-02 | 2017-06-01 | Samuel CHAIT AUERBACH Jaime | Composicion oral veterinaria con gabapentina. |
US10874626B2 (en) * | 2016-04-07 | 2020-12-29 | Nevakar Inc. | Formulation for use in a method of treatment of pain |
WO2017200700A1 (en) * | 2016-05-16 | 2017-11-23 | PixarBio Corporation | Methods for treating incisional pain |
WO2019067768A2 (en) * | 2017-09-28 | 2019-04-04 | Nevakar, Inc. | FIXED DOSE COMBINATION FORMULATIONS FOR THE TREATMENT OF PAIN |
EP3691748A4 (en) | 2017-10-03 | 2021-07-07 | Nevakar, Inc | ACETAMINOPHEN-PREGABALIN COMBINATIONS AND METHODS OF TREATMENT OF PAIN |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4694010A (en) | 1985-08-16 | 1987-09-15 | New York University | Anticonvulsant compositions and method |
AU4078897A (en) * | 1996-08-23 | 1998-03-06 | Algos Pharmaceutical Corporation | Anticonvulsant containing composition for treating neuropathic pain |
AU8668598A (en) * | 1997-08-20 | 1999-03-08 | University Of Oklahoma, The | Gaba analogs to prevent and treat gastrointestinal damage |
ATE311867T1 (de) * | 1997-09-08 | 2005-12-15 | Warner Lambert Co | Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen |
-
2000
- 2000-01-27 WO PCT/US2000/002080 patent/WO2000053225A1/en not_active Application Discontinuation
- 2000-01-27 AU AU32166/00A patent/AU3216600A/en not_active Abandoned
- 2000-01-27 US US09/936,394 patent/US6451857B1/en not_active Expired - Fee Related
- 2000-01-27 EP EP00909998A patent/EP1161263A1/en not_active Ceased
- 2000-01-27 JP JP2000603714A patent/JP2002538221A/ja not_active Withdrawn
- 2000-01-27 BR BR0008847-1A patent/BR0008847A/pt not_active IP Right Cessation
- 2000-01-27 CA CA002359485A patent/CA2359485A1/en not_active Abandoned
- 2000-02-23 AR ARP000100763A patent/AR022723A1/es unknown
- 2000-03-08 PE PE2000000204A patent/PE20001558A1/es not_active Application Discontinuation
- 2000-03-08 UY UY26052A patent/UY26052A1/es not_active Application Discontinuation
- 2000-03-08 CO CO00016924A patent/CO5150189A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP1161263A1 (en) | 2001-12-12 |
JP2002538221A (ja) | 2002-11-12 |
PE20001558A1 (es) | 2001-01-28 |
UY26052A1 (es) | 2000-08-21 |
US6451857B1 (en) | 2002-09-17 |
CA2359485A1 (en) | 2000-09-14 |
AR022723A1 (es) | 2002-09-04 |
BR0008847A (pt) | 2001-12-26 |
AU3216600A (en) | 2000-09-28 |
WO2000053225A1 (en) | 2000-09-14 |
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