CO5150189A1 - Composiciones analgesicas que comprenden compuestos antiepilepticos y metodos para usarlas - Google Patents
Composiciones analgesicas que comprenden compuestos antiepilepticos y metodos para usarlasInfo
- Publication number
- CO5150189A1 CO5150189A1 CO00016924A CO00016924A CO5150189A1 CO 5150189 A1 CO5150189 A1 CO 5150189A1 CO 00016924 A CO00016924 A CO 00016924A CO 00016924 A CO00016924 A CO 00016924A CO 5150189 A1 CO5150189 A1 CO 5150189A1
- Authority
- CO
- Colombia
- Prior art keywords
- methods
- effective amount
- analgesic compositions
- antiepileptic compounds
- compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una combinación de una cantidad efectiva de al menos un compuesto antiepiléptico con propiedades que alivian el dolor seleccionados entre gabapentina, pregabalina, carbamazepina, lamotrogina, fenitoína, fosfenitoina y análogos de los mismos, y una cantidad efectiva de al menos un compuesto seleccionado del grupo que consiste en antagonistas del receptor de N-metil-D-aspartato (NMDA), seleccionado entre dextrorfán, dextrometorfán, ketamina, ifenprodil, (15,25)-1-(4-hidroxifenil)2-(4-hidroxi-4-fenilpiperidina)-1-propanol, drogas antiinflamatorias no esteroides (NSAID) seleccionadas entre naproxeno, ibuprofeno, naprosin, diclorofenac, ketofreno, tolmetina, sulindac y análogos.<EMI FILE="00016924_1" ID="1" IMF=JPEG >
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12373999P | 1999-03-10 | 1999-03-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5150189A1 true CO5150189A1 (es) | 2002-04-29 |
Family
ID=22410582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO00016924A CO5150189A1 (es) | 1999-03-10 | 2000-03-08 | Composiciones analgesicas que comprenden compuestos antiepilepticos y metodos para usarlas |
Country Status (11)
Country | Link |
---|---|
US (1) | US6451857B1 (es) |
EP (1) | EP1161263A1 (es) |
JP (1) | JP2002538221A (es) |
AR (1) | AR022723A1 (es) |
AU (1) | AU3216600A (es) |
BR (1) | BR0008847A (es) |
CA (1) | CA2359485A1 (es) |
CO (1) | CO5150189A1 (es) |
PE (1) | PE20001558A1 (es) |
UY (1) | UY26052A1 (es) |
WO (1) | WO2000053225A1 (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0934061T6 (en) | 1996-07-24 | 2015-01-26 | Warner Lambert Co | Isobutylgaba and its derivatives for the treatment of pain |
EP1011658B1 (en) | 1997-09-08 | 2005-12-07 | Warner-Lambert Company Llc | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
MXPA02000170A (es) * | 1999-07-02 | 2002-07-02 | Warner Lambert Co | Una combinacion sinergica: gabapentin y pregablin. |
ZA200108038B (en) * | 2000-10-02 | 2003-04-01 | Pfizer Prod Inc | Prophylactic use of n-methyl-d-asparrate (NMDA) antagonists. |
CA2449987C (en) | 2001-06-07 | 2015-11-03 | Christine N. Sang | Treatment of central neuropathic pain |
SI1423168T1 (sl) * | 2001-09-03 | 2006-06-30 | Newron Pharm Spa | Farmacevtski sestavek, ki vsebuje gabapentin ali njegov analog in alfa-aminoamid, in njegova analgetska uporaba |
TWI312285B (en) | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
US7612112B2 (en) | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
US6730667B2 (en) * | 2001-11-26 | 2004-05-04 | William R. Deagle | Iontophoresis disc pain blocker |
WO2003061656A1 (en) * | 2002-01-16 | 2003-07-31 | Endo Pharmaceuticals Inc. | Pharmaceutical composition and method for treating disorders of the central nervous system |
AU2003207219A1 (en) | 2002-02-05 | 2003-09-02 | Ajinomoto Co., Inc. | Medicinal compositions containing gabapentin or pregabalin and n-type calcium channel antagonist |
CA2476438A1 (en) * | 2002-02-22 | 2003-08-28 | Warner-Lambert Company Llc | Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2 |
US20050089559A1 (en) | 2003-10-23 | 2005-04-28 | Istvan Szelenyi | Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
FR2862875B1 (fr) * | 2003-12-02 | 2006-04-07 | Mathey Acoustique Service | Preparation pharmaceutique pour le traitement des acouphenes |
WO2005102390A2 (en) * | 2004-04-22 | 2005-11-03 | Pfizer Japan, Inc. | Combinations comprising alpha-2-delta ligands and nmda receptor antagonists |
SI1963280T1 (sl) | 2005-12-22 | 2016-02-29 | Newron Pharmaceuticals S.P.A. | 2-feniletilamino derivati kot modulatorji kalcijevih in/ali natrijevih kanalčkov |
US20090176882A1 (en) | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
US7960436B2 (en) * | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
MX2009002002A (es) * | 2006-08-23 | 2009-07-22 | Valeant Pharmaceuticals Int | Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potasio. |
US8993593B2 (en) * | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
MX2009005652A (es) * | 2006-11-28 | 2009-08-07 | Valeant Pharmaceuticals Int | Analogos 1,4 diamino biciclicos de retigabina como moduladores de canales de potasio. |
EA017171B1 (ru) * | 2006-12-22 | 2012-10-30 | Рекордати Айерленд Лимитед | КОМБИНИРОВАННАЯ ТЕРАПИЯ ЗАБОЛЕВАНИЙ НИЖНИХ МОЧЕВЫВОДЯЩИХ ПУТЕЙ С ИСПОЛЬЗОВАНИЕМ ЛИГАНДОВ αδ И НЕСТЕРОИДНЫХ ПРОТИВОВОСПАЛИТЕЛЬНЫХ ПРЕПАРАТОВ (НПВП) |
US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
US8563566B2 (en) * | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
EP2116539A1 (en) | 2008-04-25 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof |
EP2116618A1 (en) | 2008-05-09 | 2009-11-11 | Agency for Science, Technology And Research | Diagnosis and treatment of Kawasaki disease |
US20100190752A1 (en) | 2008-09-05 | 2010-07-29 | Gruenenthal Gmbh | Pharmaceutical Combination |
CN102223791A (zh) | 2008-09-27 | 2011-10-19 | 塔阿克斯有限公司 | 用于神经病变治疗的局部用制剂 |
AU2009302241B2 (en) | 2008-10-08 | 2015-10-29 | Xgene Pharmaceutical Inc. | GABA conjugates and methods of use thereof |
MX2016007286A (es) * | 2013-12-17 | 2016-08-04 | Esteve Labor Dr | Combinaciones de gabapentinoides y ligandos de receptores sigma. |
AU2014364647A1 (en) | 2013-12-17 | 2016-06-23 | Laboratorios Del Dr. Esteve, S.A. | Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) and Sigma receptor ligands combinations |
CA2951987C (en) | 2014-06-16 | 2017-10-24 | Farmaceuticos Rayere, S.A. | Pharmaceutical composition that combines an anticonvulsant and a nicotinic acid derivative |
MX2015016589A (es) | 2015-12-02 | 2017-06-01 | Samuel CHAIT AUERBACH Jaime | Composicion oral veterinaria con gabapentina. |
US10052296B2 (en) * | 2016-04-07 | 2018-08-21 | Nevakar Inc. | Formulations for treating pain |
WO2017200700A1 (en) * | 2016-05-16 | 2017-11-23 | PixarBio Corporation | Methods for treating incisional pain |
US11590094B2 (en) | 2017-09-28 | 2023-02-28 | Nevakar Injectables Inc. | Fixed dose combination formulations for treating pain |
US11547686B2 (en) | 2017-10-03 | 2023-01-10 | Nevakar Injectables Inc. | Acetaminophen pregabalin combinations and methods of treating pain |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4694010A (en) * | 1985-08-16 | 1987-09-15 | New York University | Anticonvulsant compositions and method |
JP2001500121A (ja) * | 1996-08-23 | 2001-01-09 | アルゴス ファーマシューティカル コーポレーション | 神経障害性の痛みを治療する組成物を含む抗けいれん剤 |
WO1999008670A1 (en) | 1997-08-20 | 1999-02-25 | Guglietta, Antonio | Gaba analogs to prevent and treat gastrointestinal damage |
EP1011658B1 (en) | 1997-09-08 | 2005-12-07 | Warner-Lambert Company Llc | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
-
2000
- 2000-01-27 WO PCT/US2000/002080 patent/WO2000053225A1/en not_active Application Discontinuation
- 2000-01-27 US US09/936,394 patent/US6451857B1/en not_active Expired - Fee Related
- 2000-01-27 AU AU32166/00A patent/AU3216600A/en not_active Abandoned
- 2000-01-27 JP JP2000603714A patent/JP2002538221A/ja not_active Withdrawn
- 2000-01-27 BR BR0008847-1A patent/BR0008847A/pt not_active IP Right Cessation
- 2000-01-27 EP EP00909998A patent/EP1161263A1/en not_active Ceased
- 2000-01-27 CA CA002359485A patent/CA2359485A1/en not_active Abandoned
- 2000-02-23 AR ARP000100763A patent/AR022723A1/es unknown
- 2000-03-08 PE PE2000000204A patent/PE20001558A1/es not_active Application Discontinuation
- 2000-03-08 CO CO00016924A patent/CO5150189A1/es unknown
- 2000-03-08 UY UY26052A patent/UY26052A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AR022723A1 (es) | 2002-09-04 |
EP1161263A1 (en) | 2001-12-12 |
BR0008847A (pt) | 2001-12-26 |
UY26052A1 (es) | 2000-08-21 |
CA2359485A1 (en) | 2000-09-14 |
US6451857B1 (en) | 2002-09-17 |
WO2000053225A1 (en) | 2000-09-14 |
JP2002538221A (ja) | 2002-11-12 |
AU3216600A (en) | 2000-09-28 |
PE20001558A1 (es) | 2001-01-28 |
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