DK0845989T3 - Smertelindrende lægemiddelsammensætning - Google Patents
Smertelindrende lægemiddelsammensætningInfo
- Publication number
- DK0845989T3 DK0845989T3 DK96926846T DK96926846T DK0845989T3 DK 0845989 T3 DK0845989 T3 DK 0845989T3 DK 96926846 T DK96926846 T DK 96926846T DK 96926846 T DK96926846 T DK 96926846T DK 0845989 T3 DK0845989 T3 DK 0845989T3
- Authority
- DK
- Denmark
- Prior art keywords
- drug composition
- pain relieving
- relieving drug
- analgesic
- nmda
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 2
- 229940000425 combination drug Drugs 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/510,546 US5840731A (en) | 1995-08-02 | 1995-08-02 | Pain-alleviating drug composition and method for alleviating pain |
| PCT/US1996/012597 WO1997004780A2 (en) | 1995-08-02 | 1996-07-31 | Pain-alleviating drug composition and method for alleviating pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0845989T3 true DK0845989T3 (da) | 2002-04-29 |
Family
ID=24031191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96926846T DK0845989T3 (da) | 1995-08-02 | 1996-07-31 | Smertelindrende lægemiddelsammensætning |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US5840731A (da) |
| EP (1) | EP0845989B1 (da) |
| JP (1) | JP3924321B2 (da) |
| AT (1) | ATE214277T1 (da) |
| AU (1) | AU6686596A (da) |
| CA (1) | CA2228249C (da) |
| DE (1) | DE69619832T2 (da) |
| DK (1) | DK0845989T3 (da) |
| ES (1) | ES2170865T3 (da) |
| PT (1) | PT845989E (da) |
| WO (1) | WO1997004780A2 (da) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN605795A0 (en) | 1995-10-19 | 1995-11-09 | F.H. Faulding & Co. Limited | Analgesic pharmaceutical composition |
| WO1998053825A1 (en) * | 1997-05-27 | 1998-12-03 | Algos Pharmaceutical Corporation | Analgesic drug composition containing a capsaicinoid and potentiator therefor |
| US5900420A (en) * | 1997-06-19 | 1999-05-04 | Cole; William L. | Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine |
| US6204271B1 (en) * | 1997-09-16 | 2001-03-20 | Solvay Pharmaceuticals Gmbh | Analgesic composition and method for using same |
| RS49982B (sr) | 1997-09-17 | 2008-09-29 | Euro-Celtique S.A., | Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2 |
| US6245357B1 (en) * | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
| US8524277B2 (en) * | 1998-03-06 | 2013-09-03 | Alza Corporation | Extended release dosage form |
| US6007841A (en) * | 1998-03-13 | 1999-12-28 | Algos Pharmaceutical Corporation | Analgesic composition and method for treating pain |
| US6376467B1 (en) * | 1998-10-09 | 2002-04-23 | The Regents Of The University Of California | Use of inhibitors of protein kinase C epsilon to treat pain |
| WO2000003716A1 (en) * | 1998-07-16 | 2000-01-27 | Memorial Sloan-Kettering Cancer Center | Topical compositions comprising an opioid analgesic and an nmda antagonist |
| US6890951B2 (en) | 1998-08-05 | 2005-05-10 | Brookhaven Science Associates Llc | Treatment of addiction and addiction-related behavior |
| WO2001082914A2 (en) | 2000-04-28 | 2001-11-08 | Memorial Sloan-Kettering Cancer Center | Topical anesthetic/opioid formulations and uses thereof |
| US6525062B2 (en) | 2000-06-09 | 2003-02-25 | The Regents Of The University Of California | Method of treating pain using nalbuphine and opioid antagonists |
| JP2005506292A (ja) * | 2001-03-08 | 2005-03-03 | エモリー ユニバーシティ | pHに依存するNMDAレセプターアンタゴニスト |
| US7820688B2 (en) * | 2001-04-27 | 2010-10-26 | Memorial Sloan-Kettering Cancer Center | Topical anesthetic/opioid formulations and uses thereof |
| DE60239801D1 (de) * | 2001-06-05 | 2011-06-01 | Control Delivery Systems Watertown | Analgetika mit verzögerter wirkstoffabgabe |
| ATE491474T1 (de) * | 2001-06-07 | 2011-01-15 | Sang Christine Dr | Behandlung von neuropathischen schmerzen mittels eines n-methyl-d-aspartate (nmda)-rezeptor- antagonists |
| EP1415482A1 (en) * | 2001-07-27 | 2004-05-06 | Koninklijke Philips Electronics N.V. | Autostereoscopic image display with observer tracking system |
| US20050159439A1 (en) * | 2001-10-24 | 2005-07-21 | Marco Pappagallo | Management of postoperative pain |
| EP1448231A1 (en) * | 2001-11-19 | 2004-08-25 | Control Delivery Systems, Inc. | Topical delivery of codrugs |
| US20060167032A1 (en) * | 2002-01-16 | 2006-07-27 | Galer Bradley S | Pharmaceutical composition and method for treating disorders of the central nervous system |
| GB0206505D0 (en) * | 2002-03-19 | 2002-05-01 | Euro Celtique Sa | Pharmaceutical combination |
| US7666876B2 (en) | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
| US7220862B2 (en) * | 2002-06-05 | 2007-05-22 | Bristol-Myers Squibb Company | Calcitonin gene related peptide receptor antagonists |
| US7842808B2 (en) * | 2002-06-05 | 2010-11-30 | Bristol-Myers Squibb Company | Anti-migraine spirocycles |
| US6864271B2 (en) | 2002-11-12 | 2005-03-08 | The Foundation For The Lsu Health Sciences Center | Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives |
| SI1575569T1 (sl) | 2002-12-13 | 2010-12-31 | Durect Corp | Oralni sistem dostave zdravila, ki obsega visokoviskozne tekoče nosilne materiale |
| AU2003296954A1 (en) * | 2002-12-13 | 2004-07-09 | The Regents Of The University Of California | Analgesic combination comprising nalbuphine |
| GB0300531D0 (en) | 2003-01-10 | 2003-02-12 | West Pharm Serv Drug Res Ltd | Pharmaceutical compositions |
| US20040157784A1 (en) * | 2003-02-10 | 2004-08-12 | Jame Fine Chemicals, Inc. | Opiod tannate compositions |
| HUP0300929A3 (en) * | 2003-04-09 | 2005-06-28 | Richter Gedeon Vegyeszet | Analgetic and/or muscle relaxant pharmaceutical composition |
| US20040213828A1 (en) * | 2003-04-23 | 2004-10-28 | Smith David J. | Pain relief lollipop compositions and methods |
| US20040259809A1 (en) * | 2003-06-17 | 2004-12-23 | Pediamed Pharmaceuticals, Inc. | Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof |
| US9492541B2 (en) * | 2004-09-14 | 2016-11-15 | Sovereign Pharmaceuticals, Llc | Phenylepherine containing dosage form |
| US20050203115A1 (en) * | 2004-03-10 | 2005-09-15 | Sancilio Frederick D. | Narcotic-NSAID ion pairs |
| US7404970B2 (en) * | 2004-04-13 | 2008-07-29 | Konec, Inc. | Pain relief composition, method to form same, and method to use same |
| WO2006055672A2 (en) * | 2004-11-16 | 2006-05-26 | Limerick Neurosciences, Inc. | Methods and compositions for treating pain |
| US20070087977A1 (en) * | 2004-11-16 | 2007-04-19 | Wendye Robbins | Methods and compositions for treating pain |
| US20060223786A1 (en) * | 2005-04-01 | 2006-10-05 | Smith David J | Transdermal pain control method and device |
| US20090306119A1 (en) * | 2006-03-15 | 2009-12-10 | Michael Keane | Non-Codeine Opioid Analgesic Process And Formulations |
| US20070248657A1 (en) * | 2006-04-25 | 2007-10-25 | Smith David J | Multi-compartment transdermal pain control device |
| EP2039359A4 (en) * | 2006-07-12 | 2009-11-25 | Aska Pharm Co Ltd | ANALGICAL AGENT |
| EP2813144A1 (en) | 2006-10-09 | 2014-12-17 | Charleston Laboratories, Inc. | Analgesic compositions comprising an antihistamine |
| CN103497114A (zh) | 2007-06-29 | 2014-01-08 | 埃莫里大学 | 用于神经保护的nmda受体拮抗剂 |
| US20090110724A1 (en) * | 2007-10-31 | 2009-04-30 | Everett Laboratories, Inc. | Compositions and methods for treatment of pain |
| EP3326621A1 (en) | 2007-12-06 | 2018-05-30 | Durect Corporation | Oral pharmaceutical dosage forms |
| EP3090743A1 (en) | 2008-01-09 | 2016-11-09 | Charleston Laboratories, Inc. | Pharmaceutical compositions for treating headache and eliminating nausea |
| US20090191257A1 (en) * | 2008-01-29 | 2009-07-30 | Innovative Pharmaceuticals, Llc | Pain relief lollipop compositions and methods |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| US20100221313A1 (en) * | 2008-12-01 | 2010-09-02 | Innovative Pharmaceuticals, Llc | Transdermal reservoir patch |
| EP3417708B1 (en) * | 2009-03-12 | 2020-06-17 | Cumberland Pharmaceuticals, Inc. | Administration of intravenous ibuprofen |
| CA2767576C (en) | 2009-07-08 | 2020-03-10 | Charleston Laboratories Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
| US8871810B2 (en) | 2009-07-15 | 2014-10-28 | Cumberland Pharmaceuticals Inc. | Treating critically ill patients with intravenous ibuprofen |
| US10525054B2 (en) | 2011-11-07 | 2020-01-07 | Inheris Biopharma, Inc. | Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound |
| JP6593993B2 (ja) | 2011-11-07 | 2019-10-23 | ネクター セラピューティクス | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
| US9072710B2 (en) | 2012-03-16 | 2015-07-07 | Cumberland Pharmaceuticals Inc. | Injectable ibuprofen formulation |
| US9572885B2 (en) | 2013-03-15 | 2017-02-21 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| EP3086793B1 (en) | 2013-12-24 | 2022-05-11 | Virginia Commonwealth University | Use of oxygenated cholesterol sulfates (ocs) for the treatment of kidney dysfunction |
| AU2015277053B2 (en) | 2014-06-20 | 2020-01-23 | Lohocla Research Corporation | Multifunctional aminoquinoline therapeutic agents |
| AU2015290098B2 (en) | 2014-07-17 | 2018-11-01 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
| EP3423041A4 (en) | 2016-03-04 | 2019-09-11 | Charleston Laboratories, Inc. | PHARMACEUTICAL COMPOSITIONS |
| SG11201811760VA (en) | 2016-07-06 | 2019-01-30 | Durect Corp | Oral dosage form with drug composition, barrier layer and drug layer |
| AU2017364077A1 (en) | 2016-11-22 | 2019-06-20 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| WO2018191477A1 (en) * | 2017-04-14 | 2018-10-18 | Kempharm, Inc. | Dextrorphan prodrugs and processes for making and using them |
| EP3658612A4 (en) | 2017-07-25 | 2021-06-02 | Elektrofi, Inc. | FORMATION OF PARTICLES WITH SUBSTANCES |
| WO2019226969A1 (en) | 2018-05-24 | 2019-11-28 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| WO2020160323A2 (en) | 2019-01-31 | 2020-08-06 | Elektrofi, Inc. | Particle formation and morphology |
| JP7781743B2 (ja) | 2019-09-13 | 2025-12-08 | エレクトロフィ,インコーポレイテッド | 疾患の処置のための治療用生物学的作用剤の送達のための組成物及び方法 |
| CN115484934A (zh) | 2020-04-17 | 2022-12-16 | 伊勒卓菲公司 | 通过连续液滴形成和脱水形成颗粒的方法 |
| US11382873B1 (en) * | 2021-01-08 | 2022-07-12 | Vitalis Analgesics LLC | Oral administration of ketamine |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316888A (en) * | 1980-04-15 | 1982-02-23 | Nelson Research & Development Co. | Method and composition of reducing pain |
| CA1194799A (en) * | 1981-12-10 | 1985-10-08 | Eric L. Nelson | Method and composition for reducing menstrual pain |
| US4446140A (en) * | 1981-12-10 | 1984-05-01 | Nelson Research & Development Company | Method and composition for treating mouth pain |
| US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| CA1267092A (en) * | 1985-02-25 | 1990-03-27 | Martin D. Hynes | Analgesic composition containing codeine |
| US4994467A (en) * | 1989-05-31 | 1991-02-19 | Zimmerman Andrew W | Treating autism and other developmental disorders in children with NMDA receptor antagonists |
| US5013540A (en) * | 1989-11-30 | 1991-05-07 | Board Of Regents, The University Of Texas System | Using NMDA receptor antagonists to reduce damage due to laser treatment |
| US5164398A (en) * | 1991-04-01 | 1992-11-17 | Merck & Co., Inc. | Ibuprofen-antitussive combinations |
| DE122004000032I2 (de) * | 1991-09-06 | 2006-02-09 | Mcneilab Inc | Zusammensetzung die eine Tramadol-Verbindung und Acetaminophen enth{lt, und ihre Verwendung |
| WO1993017673A1 (en) * | 1992-03-03 | 1993-09-16 | Top Gold Pty., Limited | Sustained release analgesics |
| US5348747A (en) * | 1992-03-05 | 1994-09-20 | American Home Products Corporation | Pharmaceutical coating sugars |
| US5321012A (en) * | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| CA2115792C (en) * | 1993-03-05 | 2005-11-01 | David J. Mayer | Method for the treatment of pain |
| JPH10505087A (ja) * | 1994-09-02 | 1998-05-19 | バージニア カマンウェルス ユニバーシティ | 非麻薬性鎮痛剤および無痛エンハンサーを含有する疼痛緩和組成物 |
-
1995
- 1995-08-02 US US08/510,546 patent/US5840731A/en not_active Expired - Fee Related
-
1996
- 1996-07-31 JP JP50789697A patent/JP3924321B2/ja not_active Expired - Fee Related
- 1996-07-31 CA CA002228249A patent/CA2228249C/en not_active Expired - Fee Related
- 1996-07-31 AU AU66865/96A patent/AU6686596A/en not_active Abandoned
- 1996-07-31 DE DE69619832T patent/DE69619832T2/de not_active Expired - Fee Related
- 1996-07-31 WO PCT/US1996/012597 patent/WO1997004780A2/en not_active Ceased
- 1996-07-31 DK DK96926846T patent/DK0845989T3/da active
- 1996-07-31 AT AT96926846T patent/ATE214277T1/de not_active IP Right Cessation
- 1996-07-31 PT PT96926846T patent/PT845989E/pt unknown
- 1996-07-31 EP EP96926846A patent/EP0845989B1/en not_active Expired - Lifetime
- 1996-07-31 ES ES96926846T patent/ES2170865T3/es not_active Expired - Lifetime
-
1997
- 1997-07-07 US US08/888,728 patent/US5869498A/en not_active Expired - Fee Related
- 1997-07-07 US US08/889,041 patent/US5863922A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997004780A2 (en) | 1997-02-13 |
| US5869498A (en) | 1999-02-09 |
| EP0845989B1 (en) | 2002-03-13 |
| JPH11512081A (ja) | 1999-10-19 |
| AU6686596A (en) | 1997-02-26 |
| DE69619832T2 (de) | 2002-10-31 |
| US5840731A (en) | 1998-11-24 |
| WO1997004780A3 (en) | 1997-03-27 |
| EP0845989A2 (en) | 1998-06-10 |
| JP3924321B2 (ja) | 2007-06-06 |
| ES2170865T3 (es) | 2002-08-16 |
| CA2228249C (en) | 2002-12-03 |
| ATE214277T1 (de) | 2002-03-15 |
| CA2228249A1 (en) | 1997-02-13 |
| US5863922A (en) | 1999-01-26 |
| DE69619832D1 (de) | 2002-04-18 |
| PT845989E (pt) | 2002-07-31 |
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