PE20001468A1 - Compuestos no peptidicos como secretagogos de la hormona del crecimiento - Google Patents
Compuestos no peptidicos como secretagogos de la hormona del crecimientoInfo
- Publication number
- PE20001468A1 PE20001468A1 PE2000000127A PE0001272000A PE20001468A1 PE 20001468 A1 PE20001468 A1 PE 20001468A1 PE 2000000127 A PE2000000127 A PE 2000000127A PE 0001272000 A PE0001272000 A PE 0001272000A PE 20001468 A1 PE20001468 A1 PE 20001468A1
- Authority
- PE
- Peru
- Prior art keywords
- growth hormone
- secretagogs
- peptidic compounds
- refers
- phenyl
- Prior art date
Links
- 102000018997 Growth Hormone Human genes 0.000 title abstract 3
- 108010051696 Growth Hormone Proteins 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000000122 growth hormone Substances 0.000 title abstract 3
- -1 PYRROLIDINYL Chemical group 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- 229940122361 Bisphosphonate Drugs 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241001494479 Pecora Species 0.000 abstract 1
- 150000004663 bisphosphonates Chemical class 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 244000144977 poultry Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12081399P | 1999-02-19 | 1999-02-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20001468A1 true PE20001468A1 (es) | 2000-12-20 |
Family
ID=22392709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000000127A PE20001468A1 (es) | 1999-02-19 | 2000-02-18 | Compuestos no peptidicos como secretagogos de la hormona del crecimiento |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1153034B1 (https=) |
| JP (1) | JP2002539089A (https=) |
| CN (1) | CN1179972C (https=) |
| AR (1) | AR023369A1 (https=) |
| AT (1) | ATE375996T1 (https=) |
| AU (1) | AU765642B2 (https=) |
| BR (1) | BR0008321A (https=) |
| CA (1) | CA2362303A1 (https=) |
| CO (1) | CO5160260A1 (https=) |
| DE (1) | DE60036785D1 (https=) |
| IL (1) | IL144350A0 (https=) |
| PE (1) | PE20001468A1 (https=) |
| WO (1) | WO2000049037A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6639076B1 (en) | 1998-08-18 | 2003-10-28 | Eli Lilly And Company | Growth hormone secretagogues |
| US6828331B1 (en) | 1999-02-19 | 2004-12-07 | Eli Lilly And Company | Growth hormone secretagogues |
| EP1289526A4 (en) | 2000-05-30 | 2005-03-16 | Merck & Co Inc | MELANOCORTIN RECEPTOR AGONISTS |
| PY0117895A (es) * | 2000-07-31 | 2003-11-03 | Pfizer Prod Inc | Derivados de imidazol |
| US6756385B2 (en) * | 2000-07-31 | 2004-06-29 | Pfizer Inc. | Imidazole derivatives |
| AU2001294532A1 (en) * | 2000-10-13 | 2002-04-29 | Eli Lilly And Company | Resolution process for preparation of substantially pure (r) and (s) enantiomersof 2-(4-nitroimidazolyl)-4-methoxyphenylpropionic acid and salts thereof |
| US7560490B2 (en) * | 2001-01-23 | 2009-07-14 | Gador S.A. | Composition comprising bisphosphonates for prevention and/or treatment of metabolic diseases of bones, process for preparing such composition and use thereof |
| US7125840B2 (en) | 2001-10-09 | 2006-10-24 | Eli Lilly And Company | Substituted dipeptides as growth hormone secretagogues |
| US7396846B2 (en) | 2002-04-09 | 2008-07-08 | Eli Lilly And Company | Growth hormone secretagogues |
| CN1934091B (zh) * | 2004-03-23 | 2012-02-08 | 辉瑞产品公司 | 治疗神经变性障碍的咪唑化合物 |
| WO2007034326A2 (en) | 2005-09-22 | 2007-03-29 | Pfizer Products Inc. | Imidazole compounds for the treatment of neurological disorders |
| KR20250030524A (ko) | 2019-08-09 | 2025-03-05 | 화이자 인코포레이티드 | (s)-2-(((s)-6,8-디플루오로-1,2,3,4-테트라하이드로나프탈렌-2-일)아미노)-n-(1-(2-메틸-1-(네오펜틸아미노)프로판-2-일)-1h-이미다졸-4-일)펜탄아미드의고체 상태 형태 및 이의 용도 |
| US11884634B2 (en) | 2019-08-09 | 2024-01-30 | Pfizer Inc. | Compositions of solid forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4- tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide |
| CA3230245A1 (en) | 2021-09-01 | 2023-03-09 | Springworks Therapeutics, Inc. | Synthesis of nirogacestat |
| US11504354B1 (en) | 2021-09-08 | 2022-11-22 | SpringWorks Therapeutics Inc.. | Chlorinated tetralin compounds and pharmaceutical compositions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL107836A (en) * | 1992-12-11 | 1998-01-04 | Merck & Co Inc | Spiro piperidines and homologues, their preparation and pharmaceutical preparations containing them |
| NZ258412A (en) * | 1992-12-11 | 1997-01-29 | Merck & Co Inc | Spiro-fused piperidine derivatives and pharmaceutical compositions |
| US5721250A (en) * | 1993-12-23 | 1998-02-24 | Merck & Co. Inc. | Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
| WO1998016527A1 (en) * | 1996-10-15 | 1998-04-23 | Fujisawa Pharmaceutical Co., Ltd. | Benzoxepine derivatives which promote release of growth hormone |
| ZA987385B (en) * | 1997-08-19 | 2000-04-18 | Lilly Co Eli | Growth hormone secretagogues. |
| ZA987383B (en) * | 1997-08-19 | 2000-02-17 | Lilly Co Eli | Treatment of congestive heart failure with growth hormone secretagogues. |
-
2000
- 2000-02-17 CO CO00011043A patent/CO5160260A1/es unknown
- 2000-02-18 PE PE2000000127A patent/PE20001468A1/es not_active Application Discontinuation
- 2000-02-18 WO PCT/US2000/004274 patent/WO2000049037A1/en not_active Ceased
- 2000-02-18 EP EP00913536A patent/EP1153034B1/en not_active Expired - Lifetime
- 2000-02-18 AR ARP000100708A patent/AR023369A1/es unknown
- 2000-02-18 CN CNB008037035A patent/CN1179972C/zh not_active Expired - Fee Related
- 2000-02-18 DE DE60036785T patent/DE60036785D1/de not_active Expired - Lifetime
- 2000-02-18 AT AT00913536T patent/ATE375996T1/de not_active IP Right Cessation
- 2000-02-18 JP JP2000599774A patent/JP2002539089A/ja active Pending
- 2000-02-18 IL IL14435000A patent/IL144350A0/xx unknown
- 2000-02-18 AU AU34968/00A patent/AU765642B2/en not_active Ceased
- 2000-02-18 BR BR0008321-6A patent/BR0008321A/pt not_active IP Right Cessation
- 2000-02-18 CA CA002362303A patent/CA2362303A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE375996T1 (de) | 2007-11-15 |
| JP2002539089A (ja) | 2002-11-19 |
| AU765642B2 (en) | 2003-09-25 |
| BR0008321A (pt) | 2002-01-29 |
| IL144350A0 (en) | 2002-05-23 |
| WO2000049037A1 (en) | 2000-08-24 |
| EP1153034B1 (en) | 2007-10-17 |
| CN1347420A (zh) | 2002-05-01 |
| CA2362303A1 (en) | 2000-08-24 |
| CO5160260A1 (es) | 2002-05-30 |
| AU3496800A (en) | 2000-09-04 |
| CN1179972C (zh) | 2004-12-15 |
| DE60036785D1 (de) | 2007-11-29 |
| AR023369A1 (es) | 2002-09-04 |
| EP1153034A1 (en) | 2001-11-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20001468A1 (es) | Compuestos no peptidicos como secretagogos de la hormona del crecimiento | |
| ATE211466T1 (de) | Depsipeptide, herstellung und anwendung | |
| BR0215517A (pt) | Composição anti-séptica, e, métodos para desinfetar tecido e para produzir uma composição anti-séptica | |
| UY28565A1 (es) | Nuevos compuestos | |
| PE20010126A1 (es) | Pirrolotriazinas como inhibidores de cinasas | |
| ATE395056T1 (de) | Verwendung von r-(+)-2-(3-diisopropylamino-1- phenylpropyl)-4-hydroxy-methyl- phenylisobuttersäureester hydrogenfumarat zur behandlung von harndrang-inkontinenz und anderen spasmogenen leiden | |
| PE20010286A1 (es) | Derivados de indoloxoacetil piperazina como agentes antivirales | |
| PA8593001A1 (es) | Derivados de pirimidina para el tratamiento del crecimiento celular anormal | |
| AR016977A1 (es) | Compuestos de indol 2,3-sustituidos como agentes anti-inflamatorios y analgesicos, composiciones farmaceuticas, uso, intermediarios utiles, procedimientosde preparacion | |
| PE20020419A1 (es) | Tiadiazoles y oxadiazoles como inhibidores de fosfodiesterasa-7 (pde7) | |
| PE20090189A1 (es) | Derivados de aza-piridopirimidinona como agonistas de hm74a | |
| DK0694545T3 (da) | Substituerede dibenzoxazepinforbindelser, farmaceutiske sammensætninger og anvendelsesmetoder | |
| PE20241304A1 (es) | Compuestos para el tratamiento del dolor, en particular el dolor neuropatico, y/u otras enfermedades o trastornos que se asocian con at2r y/o senalizacion mediada por at2r | |
| CO5550397A2 (es) | Orto-ciclopropil-tienil-carboxamidas con actividad fungicida | |
| DE50214138D1 (de) | Antimikrobiell wirksame 4-methyl-4-aryl-2-pentanole, deren herstellung und verwendung | |
| AR017904A1 (es) | Mezclas fungicidas y procedimentos para controlar hongos nocivos que las emplean. | |
| ES2090083T3 (es) | Derivados de cefalosporina, procedimiento para su preparacion y composicion antimicrobiana que contiene estos derivados. | |
| BRPI0413413A (pt) | feniloxazolidinonas de piperidino substituìdo tendo atividade antimicrobiana com eficácia in vivo melhorada | |
| ES2196049T3 (es) | Uso de 2-(2-alquilfenilamino)oxazolinas y -tiazolinas para la fabricacion de un medicamento con efecto alfa 2 adrenergico. | |
| PE20030858A1 (es) | Acidos 3-(imidazolil)-2-aminopropanoicos | |
| BR0004143A (pt) | Composição biocida estável, e, processo para estabilizar uma composição biocida | |
| MX9307475A (es) | Monofilamentos antimicrobianos para cepillos de dientes. | |
| ATE399526T1 (de) | Pharmazeutische und kosmetische formulierungen zur behandlung der nägel | |
| AR026451A1 (es) | Compuestos heterociclicos sililados | |
| BR0110385A (pt) | Composto, composição anti-helmìntica, acaricida ou inseticida, método de proteção de plantas ou animais de danos causados por parasitas, e, uso de um composto |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |