PE11096A1 - Genes que codifican el complejo o-cetoacido deshidrogenasa de cadena ramificada de streptomyces avermitilis - Google Patents
Genes que codifican el complejo o-cetoacido deshidrogenasa de cadena ramificada de streptomyces avermitilisInfo
- Publication number
- PE11096A1 PE11096A1 PE1994245983A PE24598394A PE11096A1 PE 11096 A1 PE11096 A1 PE 11096A1 PE 1994245983 A PE1994245983 A PE 1994245983A PE 24598394 A PE24598394 A PE 24598394A PE 11096 A1 PE11096 A1 PE 11096A1
- Authority
- PE
- Peru
- Prior art keywords
- branched
- chain
- ketoacide
- dehydrogenase complex
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/04—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
- C12Y102/04004—3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (1.2.4.4), i.e. branched-chain-alpha-ketoacid dehydrogenase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
SE REFIERE A UN SEGMENTO DE ADN AISLADO CON SECUENCIAS DE ACIDOS NUCLEICOS QUE CODIFICA UN COMPLEJO O CETOACIDO DESHIDROGENASA DE CADENA RAMIFICADA, QUE INCLUYE UNA REGION DE ADN QUE REGULA LA EXPRESION DE DICHO COMPLEJO EN UN MICROORGANISMO QUE PERTENECE AL GENERO STREPTOMICES ESPECIE AVERMITILIS. TAMBIEN SE REFIERE A NUEVOS PROCEDIMIENTOS DE POTENCIAR LA PRODUCCION DE AVERMECTINA NATURAL, A LA PRODUCCION DE UN MUTANTE bkd DE STREPTOMICES AVERMITILIS Y A LA PRODUCCION DE NUEVAS AVERMECTINAS POR FERMENTACION TAL COMO LAS QUE SE PRODUCEN ANADIENDO AL MEDIO: S-(+)-2-METIL BUTIRICO O ACIDO CICLOHEXANO CARBOXILICO
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16860293A | 1993-12-16 | 1993-12-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE11096A1 true PE11096A1 (es) | 1996-04-12 |
Family
ID=22612168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1994245983A PE11096A1 (es) | 1993-12-16 | 1994-07-06 | Genes que codifican el complejo o-cetoacido deshidrogenasa de cadena ramificada de streptomyces avermitilis |
Country Status (21)
Country | Link |
---|---|
US (1) | US5707839A (es) |
EP (1) | EP0734443A1 (es) |
JP (1) | JP2800921B2 (es) |
KR (1) | KR100209842B1 (es) |
CN (2) | CN1056189C (es) |
AU (2) | AU6805894A (es) |
BR (1) | BR9408337A (es) |
CA (1) | CA2177269A1 (es) |
CO (1) | CO4340655A1 (es) |
CZ (1) | CZ174496A3 (es) |
EC (1) | ECSP941123A (es) |
EG (1) | EG22869A (es) |
FI (1) | FI942725A (es) |
HU (1) | HUT76092A (es) |
IL (3) | IL109991A (es) |
NO (2) | NO962544L (es) |
NZ (3) | NZ329117A (es) |
PE (1) | PE11096A1 (es) |
PL (1) | PL178993B1 (es) |
WO (1) | WO1995016781A1 (es) |
ZA (1) | ZA944092B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5466102A (en) * | 1993-12-16 | 1995-11-14 | Kennametal Inc. | System for coupling machine tools |
KR20040053390A (ko) * | 1998-02-13 | 2004-06-23 | 화이자 프로덕츠 인코포레이티드 | 아베르멕틴의 비2:비1의 비를 제어할 수 있는 스트렙토마이세스 아베르미틸리스 유전자 |
US6248579B1 (en) | 1998-02-13 | 2001-06-19 | Pfizer Inc | Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins |
US6197591B1 (en) | 1998-09-14 | 2001-03-06 | Pfizer Inc. | Streptomyces avermitilis regulatory genes for increased avermectin production |
ES2272299T3 (es) * | 1999-08-12 | 2007-05-01 | Pfizer Products Inc. | Gen de streptomyces avermitilis que dirige la relacion de avermectinas b2:b1. |
DE10356092B4 (de) * | 2003-12-01 | 2008-04-03 | Siemens Audiologische Technik Gmbh | Hörgerät mit drahtlosem Übertragungssystem |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0463707A1 (en) * | 1985-12-17 | 1992-01-02 | Lubrizol Genetics Inc. | Production of polyketide antibiotics |
US5077278A (en) * | 1987-01-23 | 1991-12-31 | Pfizer Inc. | Non-natural demethylavermectins compositions and method of use |
IN167980B (es) * | 1987-01-23 | 1991-01-19 | Pfizer | |
DE3881147T2 (de) * | 1987-10-23 | 1993-09-02 | Pfizer | Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen. |
US5252474A (en) * | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
DE69023036T2 (de) * | 1989-03-31 | 1996-06-13 | Merck & Co Inc | Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung. |
-
1994
- 1994-06-09 FI FI942725A patent/FI942725A/fi unknown
- 1994-06-10 ZA ZA944092A patent/ZA944092B/xx unknown
- 1994-06-13 IL IL10999194A patent/IL109991A/xx not_active IP Right Cessation
- 1994-06-16 NZ NZ329117A patent/NZ329117A/en not_active IP Right Cessation
- 1994-06-16 BR BR9408337A patent/BR9408337A/pt unknown
- 1994-06-16 NZ NZ266526A patent/NZ266526A/en not_active IP Right Cessation
- 1994-06-16 CA CA002177269A patent/CA2177269A1/en not_active Abandoned
- 1994-06-16 JP JP7516632A patent/JP2800921B2/ja not_active Expired - Fee Related
- 1994-06-16 NZ NZ329675A patent/NZ329675A/xx not_active IP Right Cessation
- 1994-06-16 CZ CZ961744A patent/CZ174496A3/cs unknown
- 1994-06-16 KR KR1019960703207A patent/KR100209842B1/ko not_active IP Right Cessation
- 1994-06-16 PL PL94314977A patent/PL178993B1/pl unknown
- 1994-06-16 HU HU9601644A patent/HUT76092A/hu unknown
- 1994-06-16 EP EP94916371A patent/EP0734443A1/en not_active Withdrawn
- 1994-06-16 CN CN94194516A patent/CN1056189C/zh not_active Expired - Fee Related
- 1994-06-16 AU AU68058/94A patent/AU6805894A/en not_active Abandoned
- 1994-06-16 WO PCT/IB1994/000157 patent/WO1995016781A1/en not_active Application Discontinuation
- 1994-07-06 PE PE1994245983A patent/PE11096A1/es not_active Application Discontinuation
- 1994-07-20 EC EC1994001123A patent/ECSP941123A/es unknown
- 1994-08-11 EG EG49194A patent/EG22869A/xx active
- 1994-12-06 CO CO94055391A patent/CO4340655A1/es unknown
-
1995
- 1995-06-06 US US08/470,892 patent/US5707839A/en not_active Expired - Fee Related
-
1996
- 1996-06-14 NO NO962544A patent/NO962544L/no not_active Application Discontinuation
-
1998
- 1998-05-11 CN CN98108414A patent/CN1210150A/zh active Pending
- 1998-11-27 AU AU94219/98A patent/AU9421998A/en not_active Abandoned
-
2003
- 2003-01-27 IL IL15416203A patent/IL154162A0/xx unknown
- 2003-01-27 IL IL15416103A patent/IL154161A0/xx unknown
-
2007
- 2007-02-12 NO NO20070802A patent/NO20070802L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1995016781A1 (en) | 1995-06-22 |
HU9601644D0 (en) | 1996-08-28 |
AU9421998A (en) | 1999-03-04 |
PL178993B1 (pl) | 2000-07-31 |
IL154162A0 (en) | 2003-07-31 |
CN1210150A (zh) | 1999-03-10 |
ECSP941123A (es) | 1994-12-15 |
NZ329117A (en) | 1998-04-27 |
FI942725A0 (fi) | 1994-06-09 |
EP0734443A1 (en) | 1996-10-02 |
CZ174496A3 (cs) | 1999-05-12 |
IL154161A0 (en) | 2003-07-31 |
FI942725A (fi) | 1995-06-17 |
HUT76092A (en) | 1997-06-30 |
NO20070802L (no) | 1996-06-14 |
PL314977A1 (en) | 1996-09-30 |
CN1056189C (zh) | 2000-09-06 |
NZ266526A (en) | 1997-12-19 |
JPH09500283A (ja) | 1997-01-14 |
NZ329675A (en) | 1998-10-28 |
BR9408337A (pt) | 1997-08-19 |
IL109991A (en) | 2005-08-31 |
KR100209842B1 (ko) | 1999-07-15 |
AU6805894A (en) | 1995-07-03 |
CN1137806A (zh) | 1996-12-11 |
JP2800921B2 (ja) | 1998-09-21 |
NO962544D0 (no) | 1996-06-14 |
EG22869A (en) | 2003-09-30 |
ZA944092B (en) | 1995-12-11 |
CA2177269A1 (en) | 1995-06-22 |
US5707839A (en) | 1998-01-13 |
NO962544L (no) | 1996-06-14 |
IL109991A0 (en) | 1994-10-07 |
CO4340655A1 (es) | 1996-07-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |