IL109991A - Dna sequence comprising a gene cluster encoding branched chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis - Google Patents

Dna sequence comprising a gene cluster encoding branched chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis

Info

Publication number
IL109991A
IL109991A IL10999194A IL10999194A IL109991A IL 109991 A IL109991 A IL 109991A IL 10999194 A IL10999194 A IL 10999194A IL 10999194 A IL10999194 A IL 10999194A IL 109991 A IL109991 A IL 109991A
Authority
IL
Israel
Prior art keywords
dna sequence
branched chain
gene cluster
streptomyces avermitilis
dehydrogenase complex
Prior art date
Application number
IL10999194A
Other languages
English (en)
Other versions
IL109991A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL109991A0 publication Critical patent/IL109991A0/xx
Priority to IL15416203A priority Critical patent/IL154162A0/xx
Priority to IL15416103A priority patent/IL154161A0/xx
Publication of IL109991A publication Critical patent/IL109991A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/04Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/040043-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (1.2.4.4), i.e. branched-chain-alpha-ketoacid dehydrogenase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
IL10999194A 1993-12-16 1994-06-13 Dna sequence comprising a gene cluster encoding branched chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis IL109991A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL15416203A IL154162A0 (en) 1993-12-16 2003-01-27 Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
IL15416103A IL154161A0 (en) 1993-12-16 2003-01-27 Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16860293A 1993-12-16 1993-12-16

Publications (2)

Publication Number Publication Date
IL109991A0 IL109991A0 (en) 1994-10-07
IL109991A true IL109991A (en) 2005-08-31

Family

ID=22612168

Family Applications (3)

Application Number Title Priority Date Filing Date
IL10999194A IL109991A (en) 1993-12-16 1994-06-13 Dna sequence comprising a gene cluster encoding branched chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
IL15416103A IL154161A0 (en) 1993-12-16 2003-01-27 Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
IL15416203A IL154162A0 (en) 1993-12-16 2003-01-27 Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL15416103A IL154161A0 (en) 1993-12-16 2003-01-27 Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
IL15416203A IL154162A0 (en) 1993-12-16 2003-01-27 Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis

Country Status (21)

Country Link
US (1) US5707839A (es)
EP (1) EP0734443A1 (es)
JP (1) JP2800921B2 (es)
KR (1) KR100209842B1 (es)
CN (2) CN1056189C (es)
AU (2) AU6805894A (es)
BR (1) BR9408337A (es)
CA (1) CA2177269A1 (es)
CO (1) CO4340655A1 (es)
CZ (1) CZ174496A3 (es)
EC (1) ECSP941123A (es)
EG (1) EG22869A (es)
FI (1) FI942725A (es)
HU (1) HUT76092A (es)
IL (3) IL109991A (es)
NO (2) NO962544D0 (es)
NZ (3) NZ329675A (es)
PE (1) PE11096A1 (es)
PL (1) PL178993B1 (es)
WO (1) WO1995016781A1 (es)
ZA (1) ZA944092B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466102A (en) * 1993-12-16 1995-11-14 Kennametal Inc. System for coupling machine tools
US6248579B1 (en) * 1998-02-13 2001-06-19 Pfizer Inc Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
CN1297485A (zh) * 1998-02-13 2001-05-30 辉瑞产品公司 介导除虫菌素b2:b1比例的除虫链霉菌基因
US6197591B1 (en) 1998-09-14 2001-03-06 Pfizer Inc. Streptomyces avermitilis regulatory genes for increased avermectin production
IL147563A0 (en) * 1999-08-12 2002-08-14 Pfizer Prod Inc Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
DE10356092B4 (de) * 2003-12-01 2008-04-03 Siemens Audiologische Technik Gmbh Hörgerät mit drahtlosem Übertragungssystem

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987003907A1 (en) * 1985-12-17 1987-07-02 Lubrizol Genetics, Inc. Isolation of genes for biosynthesis of polyketide antibiotics
IN167980B (es) * 1987-01-23 1991-01-19 Pfizer
US5077278A (en) * 1987-01-23 1991-12-31 Pfizer Inc. Non-natural demethylavermectins compositions and method of use
EP0313297B1 (en) * 1987-10-23 1993-05-19 Pfizer Inc. Process for production of avermectin aglycones and cultures therefor
DE69023036T2 (de) * 1989-03-31 1996-06-13 Merck & Co Inc Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung.
US5252474A (en) * 1989-03-31 1993-10-12 Merck & Co., Inc. Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use

Also Published As

Publication number Publication date
IL109991A0 (en) 1994-10-07
NZ329675A (en) 1998-10-28
EG22869A (en) 2003-09-30
CN1210150A (zh) 1999-03-10
IL154161A0 (en) 2003-07-31
NO20070802L (no) 1996-06-14
FI942725A (fi) 1995-06-17
JP2800921B2 (ja) 1998-09-21
PE11096A1 (es) 1996-04-12
CO4340655A1 (es) 1996-07-30
KR100209842B1 (ko) 1999-07-15
CZ174496A3 (cs) 1999-05-12
NZ329117A (en) 1998-04-27
NO962544L (no) 1996-06-14
BR9408337A (pt) 1997-08-19
AU6805894A (en) 1995-07-03
US5707839A (en) 1998-01-13
PL178993B1 (pl) 2000-07-31
AU9421998A (en) 1999-03-04
JPH09500283A (ja) 1997-01-14
ZA944092B (en) 1995-12-11
CA2177269A1 (en) 1995-06-22
ECSP941123A (es) 1994-12-15
NO962544D0 (no) 1996-06-14
CN1137806A (zh) 1996-12-11
EP0734443A1 (en) 1996-10-02
HUT76092A (en) 1997-06-30
PL314977A1 (en) 1996-09-30
FI942725A0 (fi) 1994-06-09
NZ266526A (en) 1997-12-19
HU9601644D0 (en) 1996-08-28
CN1056189C (zh) 2000-09-06
WO1995016781A1 (en) 1995-06-22
IL154162A0 (en) 2003-07-31

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Legal Events

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FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees