PA8534701A1 - DERIVADOS DE [1, 2, 4] TRIAZOLO [1,5-a] PIRIDINA - Google Patents

DERIVADOS DE [1, 2, 4] TRIAZOLO [1,5-a] PIRIDINA

Info

Publication number
PA8534701A1
PA8534701A1 PA20018534701A PA8534701A PA8534701A1 PA 8534701 A1 PA8534701 A1 PA 8534701A1 PA 20018534701 A PA20018534701 A PA 20018534701A PA 8534701 A PA8534701 A PA 8534701A PA 8534701 A1 PA8534701 A1 PA 8534701A1
Authority
PA
Panama
Prior art keywords
piridine
triazolo
derivatives
receiver
compounds
Prior art date
Application number
PA20018534701A
Other languages
English (en)
Inventor
Bernd Brodbeck
Matthias Heinrich Nettekoven
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PA8534701A1 publication Critical patent/PA8534701A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

LA INVENCION DESCRIBE COMPUESTOS DE LA FORMULA GENERAL I Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. LOS COMPUESTOS TIENEN UNA BUENA AFINIDAD POR EL RECEPTOR DE ADENOSINA Y SE PUEDEN USAR ADEMAS EN EL TRATAMIENTO DE ENFERMEDADES, RELACIONADAS CON ESTE RECEPTOR.
PA20018534701A 2000-12-15 2001-12-12 DERIVADOS DE [1, 2, 4] TRIAZOLO [1,5-a] PIRIDINA PA8534701A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00127567 2000-12-15

Publications (1)

Publication Number Publication Date
PA8534701A1 true PA8534701A1 (es) 2002-08-26

Family

ID=8170683

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20018534701A PA8534701A1 (es) 2000-12-15 2001-12-12 DERIVADOS DE [1, 2, 4] TRIAZOLO [1,5-a] PIRIDINA

Country Status (21)

Country Link
US (1) US6506772B1 (es)
EP (1) EP1347974B1 (es)
JP (1) JP4049672B2 (es)
KR (1) KR100540628B1 (es)
CN (1) CN1221551C (es)
AR (1) AR031799A1 (es)
AT (1) ATE281456T1 (es)
AU (2) AU3167402A (es)
BR (1) BR0116193A (es)
CA (1) CA2437006C (es)
DE (1) DE60106974T2 (es)
DK (1) DK1347974T3 (es)
ES (1) ES2230387T3 (es)
GT (1) GT200100253A (es)
MX (1) MXPA03005334A (es)
PA (1) PA8534701A1 (es)
PE (1) PE20020666A1 (es)
PT (1) PT1347974E (es)
UY (1) UY27074A1 (es)
WO (1) WO2002048145A1 (es)
ZA (1) ZA200304481B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4101755B2 (ja) * 2001-10-08 2008-06-18 エフ．ホフマン−ラ ロシュ アーゲー ８−アミノ−〔１，２，４〕トリアゾロ〔１，５−ａ〕ピリジン−６−カルボン酸アミド
US7199119B2 (en) * 2002-10-31 2007-04-03 Amgen Inc. Antiinflammation agents
GEP20094640B (en) 2004-07-15 2009-03-10 Bristol Myers Squibb Co Aryl-and heteroaryl-substituted tetrahydro isoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
EP2046788A1 (en) * 2006-07-12 2009-04-15 Syngeta Participations AG Triazolopyridine derivatives as herbicides
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
EP2429295B1 (en) * 2009-05-12 2013-12-25 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
WO2010132487A1 (en) * 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
MX2011011907A (es) * 2009-05-12 2012-01-20 Albany Molecular Res Inc 7-([1,2,4,]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2, 3,4-tetrahidroisoquinolina y uso de la misma.
EP2757882B1 (en) 2011-09-22 2020-11-04 Merck Sharp & Dohme Corp. Imidazopyridyl compounds as aldosterone synthase inhibitors
WO2013043520A1 (en) * 2011-09-22 2013-03-28 Merck Sharp & Dohme Corp. Triazolopyridyl compounds as aldosterone synthase inhibitors
JP7399589B2 (ja) * 2018-09-12 2023-12-18 日本化薬株式会社 有害生物防除剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226735D0 (en) 1992-12-22 1993-02-17 Ici Plc Azole derivatives
US5356894A (en) 1990-05-29 1994-10-18 Rodney Peter W Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist
AU2639299A (en) 1998-02-24 1999-09-15 Kyowa Hakko Kogyo Co. Ltd. Remedies/preventives for parkinson's disease
US6355653B1 (en) 1999-09-06 2002-03-12 Hoffmann-La Roche Inc. Amino-triazolopyridine derivatives

Also Published As

Publication number Publication date
BR0116193A (pt) 2003-09-23
CN1486314A (zh) 2004-03-31
WO2002048145A1 (en) 2002-06-20
ZA200304481B (en) 2004-09-09
KR20030061446A (ko) 2003-07-18
DE60106974T2 (de) 2005-11-03
US6506772B1 (en) 2003-01-14
GT200100253A (es) 2002-07-31
DE60106974D1 (de) 2004-12-09
MXPA03005334A (es) 2004-04-02
AR031799A1 (es) 2003-10-01
JP4049672B2 (ja) 2008-02-20
PE20020666A1 (es) 2002-07-27
EP1347974B1 (en) 2004-11-03
CA2437006C (en) 2009-10-27
UY27074A1 (es) 2002-07-31
AU3167402A (en) 2002-06-24
CN1221551C (zh) 2005-10-05
ES2230387T3 (es) 2005-05-01
CA2437006A1 (en) 2002-06-20
ATE281456T1 (de) 2004-11-15
KR100540628B1 (ko) 2006-01-11
JP2004521096A (ja) 2004-07-15
DK1347974T3 (da) 2005-03-14
AU2002231674B2 (en) 2006-07-06
PT1347974E (pt) 2005-02-28
EP1347974A1 (en) 2003-10-01

Similar Documents

Publication Publication Date Title
CR6617A (es) Derivados de pirazolo (4,3d) pirimidina
JO2503B1 (en) Benzathiazole derivatives
NZ517758A (en) Pyrazolopyrimidines useful as therapeutic agents
PL373414A1 (en) 8-methoxy-(1,2,4)triazolo(1,5-a)pyridine derivatives and their use as adenosine receptor ligands
LU91710I2 (fr) Pazopanib, facultativement sous forme d'un sel ou d'un solvate pharmaceutiquement acceptable de celui-ci
BG108269A (en) Pyrazolopyrimidines as therapeutic agents
GT200100137A (es) Pro-drogas de derivados de 4-fenil-piridina.
MX2007003321A (es) Derivados heterociclicos y su uso como agentes terapeuticos.
UY27222A1 (es) Pirazolopirimidinas como agentes terapéuticos
ECSP056246A (es) DERIVADOS DE PIRROLO [3,4-c]PIRAZOL ACTIVOS COMO INHIBIDORES DE QUINASA
HN2002000028A (es) Pirimidinas inhibidoras de metaloproteinasas
UY26851A1 (es) Derivados de la 4-fenilpiridina
PA8534701A1 (es) DERIVADOS DE [1, 2, 4] TRIAZOLO [1,5-a] PIRIDINA
DE60121461D1 (de) Kondensierte pyridoindolderivate
DE60112306D1 (de) Kondensierte pyrazindionderivate als pde5 inhibitore
ATE359791T1 (de) Pyrimidin-2,4-dion-derivate als matrix- metalloproteinase-hemmer
ATE279410T1 (de) 3-aminopyrazole als inhibitoren von cyclinabhängigen kinasen
ID29790A (id) PENGGUNAAN IMIDAZO(1,5-a)-PIRIDO(3,2-e)-PIRAZINON SEBAGAI OBAT
DE60112960D1 (de) Kondensierte pyridoindolderivate
RU2002118304A (ru) Способ подавления чувства страха
UY27034A1 (es) Derivados de pirimidina
ATE337320T1 (de) Indolderivate als pde5-inhibitoren
HUP0301257A2 (hu) Szubsztituált akriloil-disztamicin-származékokat és topoizomeráz I és II inhibitorokat tartalmazó kombinált tumorellenes kompozíciók
MXPA03004023A (es) Compuestos quimicos.
ATE330958T1 (de) Pyrazino 1'2':1,6öpyrido 3,4-böindolderivate