OA13018A - Formulation and methods for the treatment of thrombocythemia. - Google Patents
Formulation and methods for the treatment of thrombocythemia. Download PDFInfo
- Publication number
- OA13018A OA13018A OA1200500203A OA1200500203A OA13018A OA 13018 A OA13018 A OA 13018A OA 1200500203 A OA1200500203 A OA 1200500203A OA 1200500203 A OA1200500203 A OA 1200500203A OA 13018 A OA13018 A OA 13018A
- Authority
- OA
- OAPI
- Prior art keywords
- anagrelide
- base form
- use according
- acceptable sait
- pharmaceutically acceptable
- Prior art date
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Classifications
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- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
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| EP (1) | EP1589973B2 (de) |
| JP (1) | JP4624978B2 (de) |
| KR (1) | KR20050111317A (de) |
| CN (1) | CN1738623A (de) |
| AP (1) | AP2103A (de) |
| AT (1) | ATE463246T1 (de) |
| AU (1) | AU2004206783B2 (de) |
| BR (1) | BRPI0406634A (de) |
| CA (1) | CA2513708C (de) |
| CO (1) | CO5640120A2 (de) |
| CY (1) | CY1110162T1 (de) |
| DE (1) | DE602004026405D1 (de) |
| DK (1) | DK1589973T4 (de) |
| EA (2) | EA010871B1 (de) |
| ES (1) | ES2344062T5 (de) |
| HR (1) | HRP20050633A2 (de) |
| IL (1) | IL169153A (de) |
| MX (1) | MXPA05007287A (de) |
| NO (1) | NO330805B1 (de) |
| OA (1) | OA13018A (de) |
| PL (1) | PL377933A1 (de) |
| PT (1) | PT1589973E (de) |
| RS (1) | RS20050524A (de) |
| SG (1) | SG153661A1 (de) |
| SI (1) | SI1589973T2 (de) |
| WO (1) | WO2004064841A1 (de) |
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| US10813960B2 (en) * | 2000-10-04 | 2020-10-27 | Paul Edward Stamets | Integrative fungal solutions for protecting bees and overcoming colony collapse disorder (CCD) |
| FR2870125B1 (fr) * | 2004-05-12 | 2010-03-26 | Dermaconcept Jmc | Formulation du type spot-on utile en cosmetologie et en dermatologie |
| US20060030574A1 (en) * | 2004-08-04 | 2006-02-09 | Shire Holdings Ag | Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors |
| US7700608B2 (en) * | 2004-08-04 | 2010-04-20 | Shire Holdings Ag | Quinazoline derivatives and their use in the treatment of thrombocythemia |
| EP2061560A2 (de) * | 2006-09-05 | 2009-05-27 | Abbott Laboratories | Bcl-hemmer zur behandlung von thrombozytenüberschuss |
| US8304420B2 (en) | 2006-11-28 | 2012-11-06 | Shire Llc | Substituted quinazolines for reducing platelet count |
| US7910597B2 (en) * | 2006-11-28 | 2011-03-22 | Shire Llc | Substituted quinazolines |
| GB0623749D0 (en) * | 2006-11-28 | 2007-01-10 | Shire Llc | Substituted quinazolines |
| GB0623750D0 (en) * | 2006-11-28 | 2007-01-10 | Shire Llc | Substituted quinazolines |
| US20150098997A1 (en) | 2013-10-07 | 2015-04-09 | Teikoku Pharma Usa, Inc. | Methods and Compositions for Treating Attention Deficit Hyperactivity Disorder, Anxiety and Insomnia Using Dexmedetomidine Transdermal Compositions |
| TWI704933B (zh) * | 2013-10-07 | 2020-09-21 | 美商帝國製藥美國股份有限公司 | 右美托咪啶經皮輸送裝置及使用其之方法 |
| WO2015054061A1 (en) | 2013-10-07 | 2015-04-16 | Teikoku Pharma Usa, Inc. | Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine |
| US11752182B2 (en) | 2014-03-10 | 2023-09-12 | Turtle Bear Holdings, Llc | Integrative fungal solutions for protecting bees |
| CN107206000A (zh) * | 2014-12-22 | 2017-09-26 | 阿鲁兹特拉生物有限公司 | 预防和治疗血小板增多的癌症患者中的转移性疾病 |
| KR20250105683A (ko) | 2016-10-31 | 2025-07-08 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 덱스메데토미딘 경피 전달 장치를 이용한 통증을 관리하는 방법 |
| CN108776180B (zh) * | 2018-03-20 | 2020-12-04 | 广西壮族自治区食品药品检验所 | 一种同时测定曲咪新乳膏中多种透皮吸收促进剂的检测方法 |
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| US3731683A (en) * | 1971-06-04 | 1973-05-08 | Alza Corp | Bandage for the controlled metering of topical drugs to the skin |
| USRE31617E (en) * | 1972-02-04 | 1984-06-26 | Bristol-Myers Company | Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones |
| US3932407A (en) * | 1973-11-19 | 1976-01-13 | Bristol-Myers Company | Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones |
| JPS49132019A (de) * | 1973-02-26 | 1974-12-18 | ||
| DE2400887A1 (de) * | 1974-01-09 | 1975-08-28 | Bayer Ag | Verfahren zur herstellung von nitroderivaten aromatischer verbindungen |
| JPS5752352B2 (de) * | 1974-02-28 | 1982-11-06 | ||
| US3983120A (en) * | 1974-11-06 | 1976-09-28 | Bristol-Myers Company | Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones |
| US3983119A (en) * | 1974-11-06 | 1976-09-28 | Bristol-Myers Company | Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones |
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-
2004
- 2004-01-23 PT PT04704524T patent/PT1589973E/pt unknown
- 2004-01-23 SG SG200701186-9A patent/SG153661A1/en unknown
- 2004-01-23 ES ES04704524T patent/ES2344062T5/es not_active Expired - Lifetime
- 2004-01-23 RS YUP-2005/0524A patent/RS20050524A/sr unknown
- 2004-01-23 HR HR20050633A patent/HRP20050633A2/xx not_active Application Discontinuation
- 2004-01-23 EA EA200501166A patent/EA010871B1/ru not_active IP Right Cessation
- 2004-01-23 EA EA200801731A patent/EA200801731A1/ru unknown
- 2004-01-23 JP JP2006500442A patent/JP4624978B2/ja not_active Expired - Fee Related
- 2004-01-23 US US10/762,566 patent/US20040209907A1/en not_active Abandoned
- 2004-01-23 MX MXPA05007287A patent/MXPA05007287A/es active IP Right Grant
- 2004-01-23 KR KR1020057012923A patent/KR20050111317A/ko not_active Ceased
- 2004-01-23 AU AU2004206783A patent/AU2004206783B2/en not_active Ceased
- 2004-01-23 AT AT04704524T patent/ATE463246T1/de active
- 2004-01-23 BR BR0406634-0A patent/BRPI0406634A/pt not_active IP Right Cessation
- 2004-01-23 AP AP2005003362A patent/AP2103A/en active
- 2004-01-23 SI SI200431451T patent/SI1589973T2/sl unknown
- 2004-01-23 EP EP04704524A patent/EP1589973B2/de not_active Expired - Lifetime
- 2004-01-23 CA CA2513708A patent/CA2513708C/en not_active Expired - Fee Related
- 2004-01-23 DK DK04704524.0T patent/DK1589973T4/da active
- 2004-01-23 DE DE602004026405T patent/DE602004026405D1/de not_active Expired - Lifetime
- 2004-01-23 WO PCT/CA2004/000096 patent/WO2004064841A1/en not_active Ceased
- 2004-01-23 CN CNA2004800023455A patent/CN1738623A/zh active Pending
- 2004-01-23 PL PL377933A patent/PL377933A1/pl not_active IP Right Cessation
- 2004-01-23 OA OA1200500203A patent/OA13018A/en unknown
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2005
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- 2005-07-28 ZA ZA200506056A patent/ZA200506056B/en unknown
- 2005-08-16 CO CO05080891A patent/CO5640120A2/es not_active Application Discontinuation
- 2005-08-18 NO NO20053874A patent/NO330805B1/no not_active IP Right Cessation
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2010
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