OA11997A - Streptomyces avermitillis gene directing the ratioof B2:B1 avermectins. - Google Patents
Streptomyces avermitillis gene directing the ratioof B2:B1 avermectins. Download PDFInfo
- Publication number
- OA11997A OA11997A OA1200200024A OA1200200024A OA11997A OA 11997 A OA11997 A OA 11997A OA 1200200024 A OA1200200024 A OA 1200200024A OA 1200200024 A OA1200200024 A OA 1200200024A OA 11997 A OA11997 A OA 11997A
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- OA
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- Prior art keywords
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/372,934 US6248579B1 (en) | 1998-02-13 | 1999-08-12 | Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins |
Publications (1)
Publication Number | Publication Date |
---|---|
OA11997A true OA11997A (en) | 2006-04-18 |
Family
ID=23470234
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA1200200024A OA11997A (en) | 1999-08-12 | 2000-07-19 | Streptomyces avermitillis gene directing the ratioof B2:B1 avermectins. |
Country Status (37)
Country | Link |
---|---|
US (8) | US6248579B1 (sh) |
EP (1) | EP1200605B1 (sh) |
JP (2) | JP3688640B2 (sh) |
KR (1) | KR100486006B1 (sh) |
CN (1) | CN1186447C (sh) |
AP (2) | AP2002002417A0 (sh) |
AR (1) | AR021450A1 (sh) |
AT (1) | ATE283363T1 (sh) |
AU (1) | AU779756B2 (sh) |
BG (1) | BG106478A (sh) |
BR (1) | BR0013093A (sh) |
CA (1) | CA2381427A1 (sh) |
CO (1) | CO5290296A1 (sh) |
CZ (1) | CZ2002297A3 (sh) |
DE (1) | DE60016231T2 (sh) |
EA (1) | EA004569B1 (sh) |
ES (1) | ES2231214T3 (sh) |
GT (2) | GT200000138CA (sh) |
HK (1) | HK1046536B (sh) |
HR (1) | HRP20020131A2 (sh) |
HU (1) | HUP0202517A2 (sh) |
IL (1) | IL147562A0 (sh) |
IS (1) | IS6249A (sh) |
MA (1) | MA26811A1 (sh) |
MX (1) | MXPA02001514A (sh) |
NO (1) | NO20020665D0 (sh) |
OA (1) | OA11997A (sh) |
PA (1) | PA8499201A1 (sh) |
PE (1) | PE20010697A1 (sh) |
PL (1) | PL353770A1 (sh) |
PT (1) | PT1200605E (sh) |
SK (1) | SK1382002A3 (sh) |
TN (1) | TNSN00170A1 (sh) |
UY (1) | UY26287A1 (sh) |
WO (1) | WO2001012822A1 (sh) |
YU (1) | YU8402A (sh) |
ZA (1) | ZA200201071B (sh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60031126T2 (de) * | 1999-08-12 | 2007-02-08 | Pfizer Products Inc., Groton | Streptomyces avermitilis gen zum regulieren des verhältnisses der b2:b1 avermectinen |
WO2003065991A2 (en) | 2002-02-05 | 2003-08-14 | Bristol-Myers Squibb Company | N-substituted3-hydroxy-4-pyridinones and pharmaceuticals containing thereof |
EP1476539B1 (en) | 2002-02-12 | 2009-03-25 | Pfizer Products Inc. | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
US7943160B2 (en) * | 2002-05-09 | 2011-05-17 | Scimetrics Limited Corp. | Pest control methods |
WO2004067549A2 (de) * | 2003-01-31 | 2004-08-12 | Max-Delbrück-Centrum für Molekulare Medizin | Peptide gegen kälteunverträglichkeit hervorrufende autoantikörper und ihre verwendung |
KR100759130B1 (ko) | 2005-02-12 | 2007-09-19 | 휴메드 주식회사 | 항 인테그린 항체 코팅스텐트 및 그의 제조방법 |
CN106148216B (zh) | 2015-03-27 | 2019-06-04 | 浙江海正药业股份有限公司 | 一种链霉菌及其生产米尔贝霉素a3的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5525506A (en) | 1987-01-23 | 1996-06-11 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
US5234831A (en) | 1987-01-23 | 1993-08-10 | Pfizer Inc | Cultures for production of B avermectins |
US5238848A (en) | 1987-01-23 | 1993-08-24 | Pfizer Inc | Cultures for production of avermectins |
US5240850A (en) | 1987-10-23 | 1993-08-31 | Pfizer Inc. | Cultures for production of avermectin aglycones |
DE3881147T2 (de) | 1987-10-23 | 1993-09-02 | Pfizer | Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen. |
US5252474A (en) | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
DE69023036T2 (de) | 1989-03-31 | 1996-06-13 | Merck & Co Inc | Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung. |
ES2204914T3 (es) | 1993-07-30 | 2004-05-01 | Pfizer Inc. | Genes que codifican el complejo alfa cetoacido deshidrogenasa de cadena ramificada de streptomyces avermitilis. |
KR100186946B1 (ko) * | 1993-10-05 | 1999-04-01 | 알렌 제이.스피겔 | 도라멕틴의 구충활성 중간체 및 도라멕틴의 제조방법 |
FI942725A (fi) | 1993-12-16 | 1995-06-17 | Pfizer | Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta |
KR20040099389A (ko) * | 1998-02-13 | 2004-11-26 | 화이자 프로덕츠 인코포레이티드 | 스트렙토마이세스 하이그로스코피쿠스 유전자 |
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1999
- 1999-08-12 US US09/372,934 patent/US6248579B1/en not_active Expired - Fee Related
-
2000
- 2000-07-19 CZ CZ2002297A patent/CZ2002297A3/cs unknown
- 2000-07-19 CA CA002381427A patent/CA2381427A1/en not_active Abandoned
- 2000-07-19 AT AT00942331T patent/ATE283363T1/de not_active IP Right Cessation
- 2000-07-19 MX MXPA02001514A patent/MXPA02001514A/es active IP Right Grant
- 2000-07-19 AP APAP/P/2002/002417A patent/AP2002002417A0/en unknown
- 2000-07-19 SK SK138-2002A patent/SK1382002A3/sk unknown
- 2000-07-19 CN CNB008117632A patent/CN1186447C/zh not_active Expired - Fee Related
- 2000-07-19 PT PT00942331T patent/PT1200605E/pt unknown
- 2000-07-19 YU YU8402A patent/YU8402A/sh unknown
- 2000-07-19 ES ES00942331T patent/ES2231214T3/es not_active Expired - Lifetime
- 2000-07-19 HU HU0202517A patent/HUP0202517A2/hu unknown
- 2000-07-19 WO PCT/IB2000/000996 patent/WO2001012822A1/en active IP Right Grant
- 2000-07-19 OA OA1200200024A patent/OA11997A/en unknown
- 2000-07-19 EA EA200200057A patent/EA004569B1/ru not_active IP Right Cessation
- 2000-07-19 EP EP00942331A patent/EP1200605B1/en not_active Expired - Lifetime
- 2000-07-19 KR KR10-2002-7001946A patent/KR100486006B1/ko not_active IP Right Cessation
- 2000-07-19 DE DE60016231T patent/DE60016231T2/de not_active Expired - Fee Related
- 2000-07-19 AP APAP/P/2002/002419A patent/AP2002002419A0/en unknown
- 2000-07-19 JP JP2001516909A patent/JP3688640B2/ja not_active Expired - Fee Related
- 2000-07-19 PL PL00353770A patent/PL353770A1/xx unknown
- 2000-07-19 IL IL14756200A patent/IL147562A0/xx unknown
- 2000-07-19 BR BR0013093-1A patent/BR0013093A/pt not_active Application Discontinuation
- 2000-07-19 AU AU57021/00A patent/AU779756B2/en not_active Ceased
- 2000-08-04 PA PA20008499201A patent/PA8499201A1/es unknown
- 2000-08-04 CO CO00058850A patent/CO5290296A1/es not_active Application Discontinuation
- 2000-08-10 UY UY26287A patent/UY26287A1/es not_active Application Discontinuation
- 2000-08-10 PE PE2000000813A patent/PE20010697A1/es not_active Application Discontinuation
- 2000-08-10 AR ARP000104129A patent/AR021450A1/es unknown
- 2000-08-11 GT GT200000138CM patent/GT200000138CA/es unknown
- 2000-08-11 TN TNTNSN00170A patent/TNSN00170A1/fr unknown
- 2000-08-11 GT GT200000138A patent/GT200000138A/es unknown
-
2001
- 2001-01-22 US US09/766,916 patent/US6509159B2/en not_active Expired - Fee Related
- 2001-01-22 US US09/766,898 patent/US6511841B2/en not_active Expired - Fee Related
-
2002
- 2002-01-25 IS IS6249A patent/IS6249A/is unknown
- 2002-02-07 MA MA26511A patent/MA26811A1/fr unknown
- 2002-02-07 ZA ZA200201071A patent/ZA200201071B/en unknown
- 2002-02-11 NO NO20020665A patent/NO20020665D0/no not_active Application Discontinuation
- 2002-02-12 HR HR20020131A patent/HRP20020131A2/hr not_active Application Discontinuation
- 2002-03-05 BG BG106478A patent/BG106478A/bg unknown
- 2002-10-30 HK HK02107834.3A patent/HK1046536B/zh not_active IP Right Cessation
- 2002-11-27 US US10/306,013 patent/US20030134313A1/en not_active Abandoned
- 2002-11-27 US US10/306,247 patent/US7029887B2/en not_active Expired - Fee Related
- 2002-11-27 US US10/306,246 patent/US20030129635A1/en not_active Abandoned
- 2002-11-27 US US10/306,249 patent/US6833263B2/en not_active Expired - Fee Related
-
2004
- 2004-12-14 US US11/011,960 patent/US7259241B2/en not_active Expired - Fee Related
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2005
- 2005-02-16 JP JP2005039041A patent/JP2005198658A/ja not_active Withdrawn
Also Published As
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