OA10916A - Cationic virosomes as transfer system for genetic material - Google Patents

Cationic virosomes as transfer system for genetic material Download PDF

Info

Publication number
OA10916A
OA10916A OA9800214A OA9800214A OA10916A OA 10916 A OA10916 A OA 10916A OA 9800214 A OA9800214 A OA 9800214A OA 9800214 A OA9800214 A OA 9800214A OA 10916 A OA10916 A OA 10916A
Authority
OA
OAPI
Prior art keywords
membrane
lipid
cell
virosomes
vesicle
Prior art date
Application number
OA9800214A
Other languages
English (en)
Inventor
Ernst Rudolf Walti
Reinhard Gluck
Peter Klein
Original Assignee
Nika Health Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nika Health Products Ltd filed Critical Nika Health Products Ltd
Publication of OA10916A publication Critical patent/OA10916A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
OA9800214A 1996-05-08 1998-11-06 Cationic virosomes as transfer system for genetic material OA10916A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96107282 1996-05-08

Publications (1)

Publication Number Publication Date
OA10916A true OA10916A (en) 2003-02-21

Family

ID=8222763

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9800214A OA10916A (en) 1996-05-08 1998-11-06 Cationic virosomes as transfer system for genetic material

Country Status (28)

Country Link
US (1) US6210708B1 (de)
EP (1) EP0902682A2 (de)
JP (1) JP2000509404A (de)
KR (1) KR100536983B1 (de)
CN (1) CN1271992C (de)
AR (1) AR007054A1 (de)
AU (1) AU710170B2 (de)
BG (1) BG102880A (de)
BR (1) BR9709224A (de)
CA (1) CA2253561A1 (de)
CO (1) CO4600638A1 (de)
CZ (1) CZ299809B6 (de)
EA (1) EA003130B1 (de)
GT (1) GT199700058A (de)
HR (1) HRP970234B1 (de)
HU (1) HUP9901790A3 (de)
ID (1) ID17934A (de)
NO (1) NO327726B1 (de)
NZ (1) NZ332666A (de)
OA (1) OA10916A (de)
PA (1) PA8429201A1 (de)
PE (1) PE65198A1 (de)
PL (1) PL199201B1 (de)
SK (1) SK152698A3 (de)
SV (1) SV1997000032A (de)
TN (1) TNSN97080A1 (de)
WO (1) WO1997041834A1 (de)
ZA (1) ZA973885B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030113347A1 (en) * 1991-05-08 2003-06-19 Schweiz. Serum- & Impfinstitut Bern Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
AU9224398A (en) * 1997-09-08 1999-03-29 Promega Corporation Method of (in vivo) transformation utilizing lipid vehicles
SE513149C2 (sv) * 1997-12-05 2000-07-17 Katarina Edwards Läkemedelsdistributionssystem med tvåstegsmålsökning, till specifika celler eller vävnad och till dess cellkärna
GB9813100D0 (en) * 1998-06-18 1998-08-19 Secr Defence Method of forming liposomes
PL355231A1 (en) * 1999-10-08 2004-04-05 Nika Health Products Limited Cationic dosper virosomes
DE50002682D1 (de) * 1999-12-17 2003-07-31 Schott Glas Induktiv aktivierbare zündkapsel für insassen-rückhaltesysteme und prüfschaltung für diese zündkapsel
WO2001052901A1 (en) * 2000-01-21 2001-07-26 Hisamitsu Pharmaceutical Co., Inc. Drugs for gene therapy
WO2003010306A1 (en) * 2001-07-23 2003-02-06 Onyx Pharmaceuticals, Inc. Viral mutants that selectively replicate in targeted human cancer cells
KR100411234B1 (ko) * 2001-08-14 2003-12-18 한국과학기술원 올리고뉴클레오티드 혼성화 미셀 및 그의 제조방법
WO2003038103A1 (en) * 2001-10-29 2003-05-08 Atso Raasmaja Method for gene transfection using synergistic combinations of cationic lipids and cationic polymers
US20040028687A1 (en) * 2002-01-15 2004-02-12 Waelti Ernst Rudolf Methods and compositions for the targeted delivery of therapeutic substances to specific cells and tissues
US20040176283A1 (en) * 2002-04-01 2004-09-09 Robinson John A. Methods and compositions for the design of synthetic vaccines
EP1562550A1 (de) * 2002-11-21 2005-08-17 Pevion Biotech Ltd. Fusogene bläschen mit hoher fusionseffizienz, methoden zu deren herstellung und arzneimittelzusammensetzungen, dieselben enthaltend
US8133733B2 (en) 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
US20090208478A1 (en) * 2003-10-24 2009-08-20 Gencia Corporation Transducible polypeptides for modifying metabolism
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
US8507277B2 (en) 2003-10-24 2013-08-13 Gencia Corporation Nonviral vectors for delivering polynucleotides
CA2543257C (en) 2003-10-24 2013-12-31 Gencia Corporation Methods and compositions for delivering polynucleotides
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
DE102004057303A1 (de) * 2004-11-26 2006-06-01 Merck Patent Gmbh Stabile Kristallmodifikationen von DOTAP Chlorid
US20070172520A1 (en) * 2005-11-18 2007-07-26 University Of South Florida Immunotargeting of Nonionic Surfactant Vesicles
US8481023B2 (en) 2006-09-15 2013-07-09 Ottawa Hospital Research Institute Oncolytic rhabdovirus
KR101242113B1 (ko) * 2010-10-22 2013-03-19 고마바이오텍(주) 유전자 전달용 양이온성 센다이 f/hn 바이로좀 복합체
WO2013032643A2 (en) * 2011-08-31 2013-03-07 Dicerna Pharmaceuticals, Inc. Lipids capable of conformational change and their use in formulations to deliver therapeutic agents to cells
WO2013050048A2 (en) * 2011-10-07 2013-04-11 Skau Aps Identification and attenuation of the immunosuppressive domains in fusion proteins of enveloped rna viruses
AU2017336199B2 (en) 2016-09-27 2020-08-20 Camurus Ab Mixtures and formulations comprising an alkyl ammonium EDTA salt
CN109055432B (zh) * 2018-08-16 2020-10-13 南京科佰生物科技有限公司 慢病毒感染试剂及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261975A (en) 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
PL296382A1 (en) * 1991-02-02 1993-11-02 Nika Health Products Ltd Li Li Artificial membrane beads containing functionally active peptides responsible for fusion as a drug administering system
EP0538437B1 (de) * 1991-05-08 1999-08-04 SCHWEIZ. SERUM- & IMPFINSTITUT BERN Wiederhergestellte Influenza-Virosomen mit immunostimulierenden und immunoverstärkenden Eigenschaften und diese enthaltende Impfstoffe
WO1993014744A1 (en) 1992-02-04 1993-08-05 Chiron Corporation Non-toxic lipid vaccine formulations
US5631237A (en) 1992-12-22 1997-05-20 Dzau; Victor J. Method for producing in vivo delivery of therapeutic agents via liposomes
US5578475A (en) * 1993-07-12 1996-11-26 Life Technologies, Inc. Composition and methods for transfecting eukaryotic cells
WO1995032706A1 (en) * 1994-05-31 1995-12-07 Inex Pharmaceuticals Corp. Virosome-mediated intracellular delivery of therapeutic agents
FR2726764B1 (fr) 1994-11-14 1997-01-31 Pasteur Merieux Serums Vacc Adjuvant pour composition vaccinale

Also Published As

Publication number Publication date
AU2776697A (en) 1997-11-26
CZ361498A3 (cs) 1999-03-17
CN1225007A (zh) 1999-08-04
PE65198A1 (es) 1998-10-16
HRP970234A2 (en) 1998-06-30
NZ332666A (en) 2000-05-26
CA2253561A1 (en) 1997-11-13
AU710170B2 (en) 1999-09-16
EP0902682A2 (de) 1999-03-24
CN1271992C (zh) 2006-08-30
EA199800992A1 (ru) 1999-06-24
BG102880A (en) 1999-05-31
US6210708B1 (en) 2001-04-03
PL199201B1 (pl) 2008-08-29
NO985137L (no) 1999-01-04
PL329853A1 (en) 1999-04-12
HRP970234B1 (en) 2002-04-30
ID17934A (id) 1998-02-12
TNSN97080A1 (fr) 2005-03-15
JP2000509404A (ja) 2000-07-25
SK152698A3 (en) 1999-05-07
CO4600638A1 (es) 1998-05-08
HUP9901790A2 (hu) 1999-08-30
KR100536983B1 (ko) 2006-06-29
SV1997000032A (es) 1998-03-27
HUP9901790A3 (en) 2010-11-29
CZ299809B6 (cs) 2008-12-03
EA003130B1 (ru) 2003-02-27
NO985137D0 (no) 1998-11-04
GT199700058A (es) 1998-10-29
KR20000010780A (ko) 2000-02-25
NO327726B1 (no) 2009-09-14
AR007054A1 (es) 1999-10-13
WO1997041834A1 (en) 1997-11-13
PA8429201A1 (es) 2000-05-24
ZA973885B (en) 1998-11-06
BR9709224A (pt) 1999-08-10

Similar Documents

Publication Publication Date Title
AU710170B2 (en) Cationic virosomes as transfer system for genetic material
US6008202A (en) Stable lipid-comprising drug delivery complexes and methods for their production
US8771728B2 (en) Stable lipid-comprising drug delivery complexes and methods for their production
US5908777A (en) Lipidic vector for nucleic acid delivery
KR100424802B1 (ko) 핵산-함유조성물,이의제조방법및용도
JP2003535832A (ja) ポリヌクレオチドおよび薬物の標的化リポソームへのカプセル化
JP2008501729A (ja) カチオン性脂質および使用方法
CN120615011A (zh) 脂质组合物及用于递送到免疫细胞的方法
AU778399B2 (en) Cationic DOSPER virosomes
HK1021317A (en) Cationic virosomes as transfer system for genetic material